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PMC:7091888 / 17556-19816 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
695 225-230 Gene denotes hACE2 Gene:59272
696 282-287 Gene denotes hDPP4 Gene:1803
697 437-447 Gene denotes hACE2/293T Gene:59272
698 519-529 Gene denotes hDPP4/293T Gene:1803
699 2093-2098 Gene denotes hACE2 Gene:59272
700 2183-2193 Gene denotes hDPP4/293T Gene:1803
701 11-21 Species denotes SARS-CoV-2 Tax:2697049
702 119-127 Species denotes SARS-CoV Tax:694009
703 160-170 Species denotes SARS-CoV-2 Tax:2697049
704 203-213 Species denotes SARS-CoV-2 Tax:2697049
705 243-251 Species denotes SARS-CoV Tax:694009
706 256-264 Species denotes MERS-CoV Tax:1335626
707 327-337 Species denotes SARS-CoV-2 Tax:2697049
708 369-379 Species denotes SARS-CoV-2 Tax:2697049
709 384-392 Species denotes SARS-CoV Tax:694009
710 481-489 Species denotes MERS-CoV Tax:1335626
711 542-550 Species denotes SARS-CoV Tax:694009
712 578-588 Species denotes SARS-CoV-2 Tax:2697049
713 593-601 Species denotes SARS-CoV Tax:694009
714 629-637 Species denotes MERS-CoV Tax:1335626
715 692-702 Species denotes SARS-CoV-2 Tax:2697049
716 707-715 Species denotes SARS-CoV Tax:694009
717 754-762 Species denotes MERS-CoV Tax:1335626
718 909-919 Species denotes SARS-CoV-2 Tax:2697049
719 942-950 Species denotes SARS-CoV Tax:694009
720 984-994 Species denotes SARS-CoV-2 Tax:2697049
721 1011-1019 Species denotes SARS-CoV Tax:694009
722 1077-1085 Species denotes MERS-CoV Tax:1335626
723 1125-1135 Species denotes SARS-CoV-2 Tax:2697049
724 1153-1161 Species denotes SARS-CoV Tax:694009
725 1175-1180 Species denotes mouse Tax:10090
726 1204-1208 Species denotes mice Tax:10090
727 1224-1233 Species denotes mammalian Tax:9606
728 1249-1257 Species denotes SARS-CoV Tax:694009
729 1293-1297 Species denotes mice Tax:10090
730 1313-1322 Species denotes mammalian Tax:9606
731 1546-1556 Species denotes SARS-CoV-2 Tax:2697049
732 1573-1581 Species denotes SARS-CoV Tax:694009
733 1725-1733 Species denotes SARS-CoV Tax:694009
734 1748-1753 Species denotes mouse Tax:10090
735 1848-1853 Species denotes mouse Tax:10090
736 2013-2023 Species denotes SARS-CoV-2 Tax:2697049
737 2048-2056 Species denotes SARS-CoV Tax:694009
738 2137-2145 Species denotes MERS-CoV Tax:1335626
739 1609-1617 Species denotes SARS-CoV Tax:694009
740 1767-1787 Disease denotes SARS-CoV-2 infection MESH:C000657245
741 2080-2089 Disease denotes infection MESH:D007239
742 2170-2179 Disease denotes infection MESH:D007239
743 231-235 CellLine denotes 293T CVCL:0063
744 288-292 CellLine denotes 293T CVCL:0063
745 2099-2103 CellLine denotes 293T CVCL:0063

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T136 175-182 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T137 236-241 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T138 293-298 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T139 342-349 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T140 449-454 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T141 531-536 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T142 555-562 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T143 968-975 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T144 1053-1060 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T145 1140-1147 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T146 1234-1238 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T147 1323-1327 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T148 1441-1444 Body_part denotes IgG http://purl.org/sig/ont/fma/fma62872
T149 1445-1453 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T150 1455-1457 Body_part denotes Ab http://purl.org/sig/ont/fma/fma62871
T151 1966-1974 Body_part denotes antibody http://purl.org/sig/ont/fma/fma62871
T152 2111-2116 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T153 2194-2199 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T286 11-19 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T287 11-15 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T288 119-127 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T289 119-123 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T290 160-168 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T291 160-164 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T292 203-211 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T293 203-207 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T294 243-251 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T295 243-247 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T296 327-335 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T297 327-331 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T298 369-377 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T299 369-373 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T300 384-392 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T301 384-388 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T302 542-550 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T303 542-546 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T304 578-586 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T305 578-582 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T306 593-601 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T307 593-597 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T308 692-700 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T309 692-696 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T310 707-715 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T311 707-711 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T312 909-917 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T313 909-913 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T314 942-950 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T315 942-946 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T316 984-992 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T317 984-988 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T318 1011-1019 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T319 1011-1015 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T320 1125-1133 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T321 1125-1129 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T322 1153-1161 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T323 1153-1157 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T324 1249-1257 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T325 1249-1253 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T326 1546-1554 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T327 1546-1550 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T328 1573-1581 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T329 1573-1577 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T330 1609-1617 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T331 1609-1613 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T332 1725-1733 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T333 1725-1729 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T334 1767-1775 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T335 1767-1771 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T336 1778-1787 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T337 2013-2021 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T338 2013-2017 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T339 2048-2056 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T340 2048-2052 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T341 2080-2089 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T342 2170-2179 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T340 105-113 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T341 129-130 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T342 231-235 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T343 231-235 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T344 231-235 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T345 236-241 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T346 288-292 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T347 288-292 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T348 288-292 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T349 293-298 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T350 443-447 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T351 443-447 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T352 443-447 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T353 449-454 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T354 456-457 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T355 525-529 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T356 525-529 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T357 525-529 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T358 531-536 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T359 538-539 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T360 657-658 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T361 925-926 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T362 928-929 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T363 956-957 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T364 959-960 http://purl.obolibrary.org/obo/CLO_0001021 denotes b
T365 1175-1180 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T366 1234-1238 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T367 1277-1283 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T368 1323-1327 http://purl.obolibrary.org/obo/GO_0005623 denotes cell
T369 1748-1753 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T370 1848-1853 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T371 2099-2103 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T372 2099-2103 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T373 2099-2103 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T374 2111-2116 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T375 2189-2193 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T376 2189-2193 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T377 2189-2193 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T378 2194-2199 http://purl.obolibrary.org/obo/GO_0005623 denotes cells

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T81 175-182 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T82 342-349 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T83 555-562 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T84 968-975 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T85 1053-1060 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T86 1140-1147 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T106 243-326 Sentence denotes SARS-CoV and MERS-CoV RBDs, as well as hDPP4/293T cells, were included as controls.
T107 327-541 Sentence denotes SARS-CoV-2 RBD protein inhibited entry of SARS-CoV-2 and SARS-CoV pseudoviruses into their respective target (hACE2/293T) cells (a), but not the entry of MERS-CoV pseudovirus into its target (hDPP4/293T) cells (a).
T108 542-660 Sentence denotes SARS-CoV RBD protein inhibited both SARS-CoV-2 and SARS-CoV pseudovirus entry, but not MERS-CoV pseudovirus entry (b).
T109 661-785 Sentence denotes MERS-CoV RBD inhibited neither SARS-CoV-2 nor SARS-CoV pseudovirus entry, but it did inhibit MERS-CoV pseudovirus entry (c).
T110 786-1195 Sentence denotes The data are presented as mean inhibition (%) ± s.e.m. (n = 4), and 50% inhibition concentration (IC50) was calculated for SARS-CoV-2 RBD (a, b, black), or SARS-CoV RBD (a, b, red), protein against SARS-CoV-2 pseudovirus and SARS-CoV pseudovirus and for MERS-CoV RBD protein (green) against MERS-CoV pseudovirus (c). d Cross-reactivity of SARS-CoV-2 RBD protein with SARS-CoV RBD-specific mouse sera by ELISA.
T111 1196-1284 Sentence denotes Sera of mice immunized with mammalian cell-expressed SARS-CoV RBD protein30 were tested.
T112 1285-1382 Sentence denotes Sera of mice immunized with mammalian cell-expressed MERS-CoV RBD protein31 were used as control.
T113 1383-1436 Sentence denotes The data are presented as mean A450 ± s.e.m. (n = 4).
T114 1437-1824 Sentence denotes The IgG antibody (Ab) titers were calculated as the endpoint dilution that remains positively detectable for SARS-CoV-2 RBD (black), or SARS-CoV RBD (red), binding to anti-SARS-CoV RBD sera (d) and for MERS-CoV RBD (green) binding to anti-MERS-CoV RBD sera (e). f Cross-neutralization of SARS-CoV RBD-immunized mouse sera against SARS-CoV-2 infection by pseudovirus neutralization assay.
T115 1825-1880 Sentence denotes MERS-CoV RBD-immunized mouse sera were used as control.
T116 1881-1948 Sentence denotes The data are presented as mean neutralization (%) ± s.e.m. (n = 4).
T117 1949-2200 Sentence denotes 50% neutralizing antibody titers (NT50) were calculated against SARS-CoV-2 pseudovirus (black), or SARS-CoV pseudovirus (red), (f) infection in hACE2/293T target cells, as well as against MERS-CoV pseudovirus (green) (g) infection in hDPP4/293T cells.
T118 2201-2260 Sentence denotes Experiments were repeated twice and yielded similar results

2_test

Id Subject Object Predicate Lexical cue
32203189-20374001-19774536 1269-1271 20374001 denotes 30
32203189-27750111-19774537 1358-1360 27750111 denotes 31