PMC:7080035 / 4606-5777 JSONTXT

Annnotations TAB JSON ListView MergeView

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7080035","sourcedb":"PMC","sourceid":"7080035","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7080035","text":"A 57-year-old man living in Wuhan presented with sore throat and fever (39.0 °C) lasting for 3 days. Laboratory testing revealed a white blood cell (WBC) count within the reference range and a slight elevation of high-sensitivity C-reactive protein (hsCRP; 6.65 mg/L, reference range 0–5 mg/L). A search for common respiratory pathogens, including Mycoplasma pneumoniae, Chlamydia pneumoniae, adenovirus, respiratory syncytial virus, and Coxsackie B-virus specific IgM, yielded negative results. A chest CT scan conducted in another hospital 2 days before revealed the presence of a GGO in the right lung, which required further diagnostic workout (differential diagnosis between a tumor and an infectious disease). 18F-FDG PET/CT identified peripheral GGOs with an increased 18F-FDG uptake (SUVmax range 2.2–4.6) in the right upper lung (Fig. 1a, b, arrows) and left lower lung (Fig. 1c; arrows). Unfortunately, SARS-CoV-2 nucleic acid testing was not performed. Antiviral, anti-inflammatory, and symptomatic treatment for 2 weeks led to complete resolution of symptoms.\nFig. 1 Peripheral GGOs with an increased 18F-FDG uptake in the right upper lung and left lower lung","divisions":[{"label":"label","span":{"begin":1072,"end":1078}}],"tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T26","span":{"begin":54,"end":60},"obj":"Body_part"},{"id":"T27","span":{"begin":131,"end":147},"obj":"Body_part"},{"id":"T28","span":{"begin":143,"end":147},"obj":"Body_part"},{"id":"T29","span":{"begin":241,"end":248},"obj":"Body_part"},{"id":"T30","span":{"begin":465,"end":468},"obj":"Body_part"},{"id":"T31","span":{"begin":498,"end":503},"obj":"Body_part"},{"id":"T32","span":{"begin":594,"end":604},"obj":"Body_part"},{"id":"T33","span":{"begin":833,"end":837},"obj":"Body_part"},{"id":"T34","span":{"begin":874,"end":878},"obj":"Body_part"},{"id":"T35","span":{"begin":1147,"end":1151},"obj":"Body_part"},{"id":"T36","span":{"begin":1167,"end":1171},"obj":"Body_part"}],"attributes":[{"id":"A26","pred":"fma_id","subj":"T26","obj":"http://purl.org/sig/ont/fma/fma228738"},{"id":"A27","pred":"fma_id","subj":"T27","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A28","pred":"fma_id","subj":"T28","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A29","pred":"fma_id","subj":"T29","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A30","pred":"fma_id","subj":"T30","obj":"http://purl.org/sig/ont/fma/fma62873"},{"id":"A31","pred":"fma_id","subj":"T31","obj":"http://purl.org/sig/ont/fma/fma9576"},{"id":"A32","pred":"fma_id","subj":"T32","obj":"http://purl.org/sig/ont/fma/fma7309"},{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A34","pred":"fma_id","subj":"T34","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A35","pred":"fma_id","subj":"T35","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A36","pred":"fma_id","subj":"T36","obj":"http://purl.org/sig/ont/fma/fma7195"},{"subj":"T26","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T27","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T28","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T29","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T30","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T31","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T32","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T33","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T34","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T35","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T36","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T21","span":{"begin":54,"end":60},"obj":"Body_part"},{"id":"T22","span":{"begin":137,"end":142},"obj":"Body_part"},{"id":"T23","span":{"begin":498,"end":503},"obj":"Body_part"},{"id":"T24","span":{"begin":594,"end":604},"obj":"Body_part"},{"id":"T25","span":{"begin":600,"end":604},"obj":"Body_part"},{"id":"T26","span":{"begin":833,"end":837},"obj":"Body_part"},{"id":"T27","span":{"begin":874,"end":878},"obj":"Body_part"},{"id":"T28","span":{"begin":1147,"end":1151},"obj":"Body_part"},{"id":"T29","span":{"begin":1167,"end":1171},"obj":"Body_part"}],"attributes":[{"id":"A21","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/UBERON_0000341"},{"id":"A22","pred":"uberon_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"},{"id":"A24","pred":"uberon_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/UBERON_0002167"},{"id":"A25","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A26","pred":"uberon_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A29","pred":"uberon_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"subj":"T21","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T22","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T23","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T24","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T26","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T27","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T28","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T29","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T22","span":{"begin":49,"end":60},"obj":"Disease"},{"id":"T23","span":{"begin":348,"end":369},"obj":"Disease"},{"id":"T24","span":{"begin":371,"end":391},"obj":"Disease"},{"id":"T25","span":{"begin":682,"end":687},"obj":"Disease"},{"id":"T26","span":{"begin":695,"end":713},"obj":"Disease"},{"id":"T27","span":{"begin":913,"end":921},"obj":"Disease"}],"attributes":[{"id":"A22","pred":"mondo_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/MONDO_0002258"},{"id":"A23","pred":"mondo_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/MONDO_0005867"},{"id":"A24","pred":"mondo_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/MONDO_0025598"},{"id":"A25","pred":"mondo_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/MONDO_0005070"},{"id":"A26","pred":"mondo_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A27","pred":"mondo_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"subj":"T22","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T23","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T24","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T26","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T27","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T38","span":{"begin":0,"end":1},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T39","span":{"begin":112,"end":119},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T40","span":{"begin":129,"end":130},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T41","span":{"begin":137,"end":142},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T42","span":{"begin":143,"end":147},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T43","span":{"begin":191,"end":192},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T44","span":{"begin":295,"end":296},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T45","span":{"begin":427,"end":432},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T46","span":{"begin":448,"end":449},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T47","span":{"begin":450,"end":455},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T48","span":{"begin":496,"end":497},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T49","span":{"begin":498,"end":503},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T50","span":{"begin":581,"end":582},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T51","span":{"begin":594,"end":604},"obj":"http://purl.obolibrary.org/obo/UBERON_0002167"},{"id":"T52","span":{"begin":680,"end":681},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T53","span":{"begin":833,"end":837},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T54","span":{"begin":833,"end":837},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T55","span":{"begin":848,"end":849},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T56","span":{"begin":874,"end":878},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T57","span":{"begin":874,"end":878},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T58","span":{"begin":937,"end":948},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T59","span":{"begin":1147,"end":1151},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T60","span":{"begin":1147,"end":1151},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T61","span":{"begin":1167,"end":1171},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T62","span":{"begin":1167,"end":1171},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"}],"attributes":[{"subj":"T38","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T39","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T40","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T45","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T46","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T47","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T48","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T49","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T50","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T51","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T52","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T53","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T54","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T55","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T56","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T57","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T58","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T59","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T60","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T61","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T62","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T24","span":{"begin":241,"end":248},"obj":"Chemical"},{"id":"T25","span":{"begin":724,"end":727},"obj":"Chemical"},{"id":"T26","span":{"begin":924,"end":936},"obj":"Chemical"},{"id":"T27","span":{"begin":932,"end":936},"obj":"Chemical"}],"attributes":[{"id":"A24","pred":"chebi_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A25","pred":"chebi_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_131701"},{"id":"A26","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_33696"},{"id":"A27","pred":"chebi_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"},{"subj":"T24","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T26","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T27","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T22","span":{"begin":49,"end":60},"obj":"Phenotype"},{"id":"T23","span":{"begin":65,"end":70},"obj":"Phenotype"},{"id":"T24","span":{"begin":359,"end":369},"obj":"Phenotype"},{"id":"T25","span":{"begin":381,"end":391},"obj":"Phenotype"},{"id":"T26","span":{"begin":682,"end":687},"obj":"Phenotype"}],"attributes":[{"id":"A22","pred":"hp_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/HP_0033050"},{"id":"A23","pred":"hp_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A24","pred":"hp_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A25","pred":"hp_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A26","pred":"hp_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/HP_0002664"},{"subj":"T22","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T23","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T24","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T26","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T6","span":{"begin":784,"end":790},"obj":"http://purl.obolibrary.org/obo/GO_0098739"},{"id":"T7","span":{"begin":784,"end":790},"obj":"http://purl.obolibrary.org/obo/GO_0098657"},{"id":"T8","span":{"begin":1121,"end":1127},"obj":"http://purl.obolibrary.org/obo/GO_0098739"},{"id":"T9","span":{"begin":1121,"end":1127},"obj":"http://purl.obolibrary.org/obo/GO_0098657"}],"attributes":[{"subj":"T6","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T9","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T45","span":{"begin":0,"end":100},"obj":"Sentence"},{"id":"T46","span":{"begin":101,"end":294},"obj":"Sentence"},{"id":"T47","span":{"begin":295,"end":495},"obj":"Sentence"},{"id":"T48","span":{"begin":496,"end":715},"obj":"Sentence"},{"id":"T49","span":{"begin":716,"end":897},"obj":"Sentence"},{"id":"T50","span":{"begin":898,"end":963},"obj":"Sentence"},{"id":"T51","span":{"begin":964,"end":1071},"obj":"Sentence"},{"id":"T52","span":{"begin":1072,"end":1171},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T45","pred":"source","obj":"LitCovid-sentences"},{"subj":"T46","pred":"source","obj":"LitCovid-sentences"},{"subj":"T47","pred":"source","obj":"LitCovid-sentences"},{"subj":"T48","pred":"source","obj":"LitCovid-sentences"},{"subj":"T49","pred":"source","obj":"LitCovid-sentences"},{"subj":"T50","pred":"source","obj":"LitCovid-sentences"},{"subj":"T51","pred":"source","obj":"LitCovid-sentences"},{"subj":"T52","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"126","span":{"begin":1090,"end":1094},"obj":"Chemical"},{"id":"127","span":{"begin":1113,"end":1120},"obj":"Chemical"},{"id":"141","span":{"begin":230,"end":248},"obj":"Gene"},{"id":"142","span":{"begin":348,"end":369},"obj":"Species"},{"id":"143","span":{"begin":371,"end":391},"obj":"Species"},{"id":"144","span":{"begin":393,"end":403},"obj":"Species"},{"id":"145","span":{"begin":405,"end":432},"obj":"Species"},{"id":"146","span":{"begin":913,"end":923},"obj":"Species"},{"id":"147","span":{"begin":315,"end":326},"obj":"Species"},{"id":"148","span":{"begin":716,"end":723},"obj":"Chemical"},{"id":"149","span":{"begin":776,"end":783},"obj":"Chemical"},{"id":"150","span":{"begin":49,"end":60},"obj":"Disease"},{"id":"151","span":{"begin":65,"end":70},"obj":"Disease"},{"id":"152","span":{"begin":682,"end":687},"obj":"Disease"},{"id":"153","span":{"begin":695,"end":713},"obj":"Disease"}],"attributes":[{"id":"A127","pred":"tao:has_database_id","subj":"127","obj":"MESH:D019788"},{"id":"A141","pred":"tao:has_database_id","subj":"141","obj":"Gene:1401"},{"id":"A142","pred":"tao:has_database_id","subj":"142","obj":"Tax:2104"},{"id":"A143","pred":"tao:has_database_id","subj":"143","obj":"Tax:83558"},{"id":"A144","pred":"tao:has_database_id","subj":"144","obj":"Tax:10508"},{"id":"A145","pred":"tao:has_database_id","subj":"145","obj":"Tax:12814"},{"id":"A146","pred":"tao:has_database_id","subj":"146","obj":"Tax:2697049"},{"id":"A147","pred":"tao:has_database_id","subj":"147","obj":"Tax:12814"},{"id":"A148","pred":"tao:has_database_id","subj":"148","obj":"MESH:D019788"},{"id":"A149","pred":"tao:has_database_id","subj":"149","obj":"MESH:D019788"},{"id":"A150","pred":"tao:has_database_id","subj":"150","obj":"MESH:D010608"},{"id":"A151","pred":"tao:has_database_id","subj":"151","obj":"MESH:D005334"},{"id":"A152","pred":"tao:has_database_id","subj":"152","obj":"MESH:D009369"},{"id":"A153","pred":"tao:has_database_id","subj":"153","obj":"MESH:D003141"},{"subj":"126","pred":"source","obj":"LitCovid-PubTator"},{"subj":"127","pred":"source","obj":"LitCovid-PubTator"},{"subj":"141","pred":"source","obj":"LitCovid-PubTator"},{"subj":"142","pred":"source","obj":"LitCovid-PubTator"},{"subj":"143","pred":"source","obj":"LitCovid-PubTator"},{"subj":"144","pred":"source","obj":"LitCovid-PubTator"},{"subj":"145","pred":"source","obj":"LitCovid-PubTator"},{"subj":"146","pred":"source","obj":"LitCovid-PubTator"},{"subj":"147","pred":"source","obj":"LitCovid-PubTator"},{"subj":"148","pred":"source","obj":"LitCovid-PubTator"},{"subj":"149","pred":"source","obj":"LitCovid-PubTator"},{"subj":"150","pred":"source","obj":"LitCovid-PubTator"},{"subj":"151","pred":"source","obj":"LitCovid-PubTator"},{"subj":"152","pred":"source","obj":"LitCovid-PubTator"},{"subj":"153","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#dd93ec","default":true},{"id":"LitCovid-PD-UBERON","color":"#93ecc3"},{"id":"LitCovid-PD-MONDO","color":"#eca993"},{"id":"LitCovid-PD-CLO","color":"#9396ec"},{"id":"LitCovid-PD-CHEBI","color":"#b0ec93"},{"id":"LitCovid-PD-HP","color":"#ec93ca"},{"id":"LitCovid-PD-GO-BP","color":"#93e4ec"},{"id":"LitCovid-sentences","color":"#ecd993"},{"id":"LitCovid-PubTator","color":"#bf93ec"}]}]}}