PMC:7080035 / 4599-5777 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T26","span":{"begin":61,"end":67},"obj":"Body_part"},{"id":"T27","span":{"begin":138,"end":154},"obj":"Body_part"},{"id":"T28","span":{"begin":150,"end":154},"obj":"Body_part"},{"id":"T29","span":{"begin":248,"end":255},"obj":"Body_part"},{"id":"T30","span":{"begin":472,"end":475},"obj":"Body_part"},{"id":"T31","span":{"begin":505,"end":510},"obj":"Body_part"},{"id":"T32","span":{"begin":601,"end":611},"obj":"Body_part"},{"id":"T33","span":{"begin":840,"end":844},"obj":"Body_part"},{"id":"T34","span":{"begin":881,"end":885},"obj":"Body_part"},{"id":"T35","span":{"begin":1154,"end":1158},"obj":"Body_part"},{"id":"T36","span":{"begin":1174,"end":1178},"obj":"Body_part"}],"attributes":[{"id":"A26","pred":"fma_id","subj":"T26","obj":"http://purl.org/sig/ont/fma/fma228738"},{"id":"A27","pred":"fma_id","subj":"T27","obj":"http://purl.org/sig/ont/fma/fma62852"},{"id":"A28","pred":"fma_id","subj":"T28","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A29","pred":"fma_id","subj":"T29","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A30","pred":"fma_id","subj":"T30","obj":"http://purl.org/sig/ont/fma/fma62873"},{"id":"A31","pred":"fma_id","subj":"T31","obj":"http://purl.org/sig/ont/fma/fma9576"},{"id":"A32","pred":"fma_id","subj":"T32","obj":"http://purl.org/sig/ont/fma/fma7309"},{"id":"A33","pred":"fma_id","subj":"T33","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A34","pred":"fma_id","subj":"T34","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A35","pred":"fma_id","subj":"T35","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A36","pred":"fma_id","subj":"T36","obj":"http://purl.org/sig/ont/fma/fma7195"}],"text":"Case 1\nA 57-year-old man living in Wuhan presented with sore throat and fever (39.0 °C) lasting for 3 days. Laboratory testing revealed a white blood cell (WBC) count within the reference range and a slight elevation of high-sensitivity C-reactive protein (hsCRP; 6.65 mg/L, reference range 0–5 mg/L). A search for common respiratory pathogens, including Mycoplasma pneumoniae, Chlamydia pneumoniae, adenovirus, respiratory syncytial virus, and Coxsackie B-virus specific IgM, yielded negative results. A chest CT scan conducted in another hospital 2 days before revealed the presence of a GGO in the right lung, which required further diagnostic workout (differential diagnosis between a tumor and an infectious disease). 18F-FDG PET/CT identified peripheral GGOs with an increased 18F-FDG uptake (SUVmax range 2.2–4.6) in the right upper lung (Fig. 1a, b, arrows) and left lower lung (Fig. 1c; arrows). Unfortunately, SARS-CoV-2 nucleic acid testing was not performed. Antiviral, anti-inflammatory, and symptomatic treatment for 2 weeks led to complete resolution of symptoms.\nFig. 1 Peripheral GGOs with an increased 18F-FDG uptake in the right upper lung and left lower lung"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T21","span":{"begin":61,"end":67},"obj":"Body_part"},{"id":"T22","span":{"begin":144,"end":149},"obj":"Body_part"},{"id":"T23","span":{"begin":505,"end":510},"obj":"Body_part"},{"id":"T24","span":{"begin":601,"end":611},"obj":"Body_part"},{"id":"T25","span":{"begin":607,"end":611},"obj":"Body_part"},{"id":"T26","span":{"begin":840,"end":844},"obj":"Body_part"},{"id":"T27","span":{"begin":881,"end":885},"obj":"Body_part"},{"id":"T28","span":{"begin":1154,"end":1158},"obj":"Body_part"},{"id":"T29","span":{"begin":1174,"end":1178},"obj":"Body_part"}],"attributes":[{"id":"A21","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/UBERON_0000341"},{"id":"A22","pred":"uberon_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A23","pred":"uberon_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/UBERON_0001443"},{"id":"A24","pred":"uberon_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/UBERON_0002167"},{"id":"A25","pred":"uberon_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A26","pred":"uberon_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A27","pred":"uberon_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A28","pred":"uberon_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A29","pred":"uberon_id","subj":"T29","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"Case 1\nA 57-year-old man living in Wuhan presented with sore throat and fever (39.0 °C) lasting for 3 days. Laboratory testing revealed a white blood cell (WBC) count within the reference range and a slight elevation of high-sensitivity C-reactive protein (hsCRP; 6.65 mg/L, reference range 0–5 mg/L). A search for common respiratory pathogens, including Mycoplasma pneumoniae, Chlamydia pneumoniae, adenovirus, respiratory syncytial virus, and Coxsackie B-virus specific IgM, yielded negative results. A chest CT scan conducted in another hospital 2 days before revealed the presence of a GGO in the right lung, which required further diagnostic workout (differential diagnosis between a tumor and an infectious disease). 18F-FDG PET/CT identified peripheral GGOs with an increased 18F-FDG uptake (SUVmax range 2.2–4.6) in the right upper lung (Fig. 1a, b, arrows) and left lower lung (Fig. 1c; arrows). Unfortunately, SARS-CoV-2 nucleic acid testing was not performed. Antiviral, anti-inflammatory, and symptomatic treatment for 2 weeks led to complete resolution of symptoms.\nFig. 1 Peripheral GGOs with an increased 18F-FDG uptake in the right upper lung and left lower lung"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T22","span":{"begin":56,"end":67},"obj":"Disease"},{"id":"T23","span":{"begin":355,"end":376},"obj":"Disease"},{"id":"T24","span":{"begin":378,"end":398},"obj":"Disease"},{"id":"T25","span":{"begin":689,"end":694},"obj":"Disease"},{"id":"T26","span":{"begin":702,"end":720},"obj":"Disease"},{"id":"T27","span":{"begin":920,"end":928},"obj":"Disease"}],"attributes":[{"id":"A22","pred":"mondo_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/MONDO_0002258"},{"id":"A23","pred":"mondo_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/MONDO_0005867"},{"id":"A24","pred":"mondo_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/MONDO_0025598"},{"id":"A25","pred":"mondo_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/MONDO_0005070"},{"id":"A26","pred":"mondo_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A27","pred":"mondo_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"Case 1\nA 57-year-old man living in Wuhan presented with sore throat and fever (39.0 °C) lasting for 3 days. Laboratory testing revealed a white blood cell (WBC) count within the reference range and a slight elevation of high-sensitivity C-reactive protein (hsCRP; 6.65 mg/L, reference range 0–5 mg/L). A search for common respiratory pathogens, including Mycoplasma pneumoniae, Chlamydia pneumoniae, adenovirus, respiratory syncytial virus, and Coxsackie B-virus specific IgM, yielded negative results. A chest CT scan conducted in another hospital 2 days before revealed the presence of a GGO in the right lung, which required further diagnostic workout (differential diagnosis between a tumor and an infectious disease). 18F-FDG PET/CT identified peripheral GGOs with an increased 18F-FDG uptake (SUVmax range 2.2–4.6) in the right upper lung (Fig. 1a, b, arrows) and left lower lung (Fig. 1c; arrows). Unfortunately, SARS-CoV-2 nucleic acid testing was not performed. Antiviral, anti-inflammatory, and symptomatic treatment for 2 weeks led to complete resolution of symptoms.\nFig. 1 Peripheral GGOs with an increased 18F-FDG uptake in the right upper lung and left lower lung"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T38","span":{"begin":7,"end":8},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T39","span":{"begin":119,"end":126},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T40","span":{"begin":136,"end":137},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T41","span":{"begin":144,"end":149},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T42","span":{"begin":150,"end":154},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T43","span":{"begin":198,"end":199},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T44","span":{"begin":302,"end":303},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T45","span":{"begin":434,"end":439},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T46","span":{"begin":455,"end":456},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T47","span":{"begin":457,"end":462},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T48","span":{"begin":503,"end":504},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T49","span":{"begin":505,"end":510},"obj":"http://www.ebi.ac.uk/efo/EFO_0000965"},{"id":"T50","span":{"begin":588,"end":589},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T51","span":{"begin":601,"end":611},"obj":"http://purl.obolibrary.org/obo/UBERON_0002167"},{"id":"T52","span":{"begin":687,"end":688},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T53","span":{"begin":840,"end":844},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T54","span":{"begin":840,"end":844},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T55","span":{"begin":855,"end":856},"obj":"http://purl.obolibrary.org/obo/CLO_0001021"},{"id":"T56","span":{"begin":881,"end":885},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T57","span":{"begin":881,"end":885},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T58","span":{"begin":944,"end":955},"obj":"http://purl.obolibrary.org/obo/UBERON_0000473"},{"id":"T59","span":{"begin":1154,"end":1158},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T60","span":{"begin":1154,"end":1158},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T61","span":{"begin":1174,"end":1178},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T62","span":{"begin":1174,"end":1178},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"}],"text":"Case 1\nA 57-year-old man living in Wuhan presented with sore throat and fever (39.0 °C) lasting for 3 days. Laboratory testing revealed a white blood cell (WBC) count within the reference range and a slight elevation of high-sensitivity C-reactive protein (hsCRP; 6.65 mg/L, reference range 0–5 mg/L). A search for common respiratory pathogens, including Mycoplasma pneumoniae, Chlamydia pneumoniae, adenovirus, respiratory syncytial virus, and Coxsackie B-virus specific IgM, yielded negative results. A chest CT scan conducted in another hospital 2 days before revealed the presence of a GGO in the right lung, which required further diagnostic workout (differential diagnosis between a tumor and an infectious disease). 18F-FDG PET/CT identified peripheral GGOs with an increased 18F-FDG uptake (SUVmax range 2.2–4.6) in the right upper lung (Fig. 1a, b, arrows) and left lower lung (Fig. 1c; arrows). Unfortunately, SARS-CoV-2 nucleic acid testing was not performed. Antiviral, anti-inflammatory, and symptomatic treatment for 2 weeks led to complete resolution of symptoms.\nFig. 1 Peripheral GGOs with an increased 18F-FDG uptake in the right upper lung and left lower lung"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T24","span":{"begin":248,"end":255},"obj":"Chemical"},{"id":"T25","span":{"begin":731,"end":734},"obj":"Chemical"},{"id":"T26","span":{"begin":931,"end":943},"obj":"Chemical"},{"id":"T27","span":{"begin":939,"end":943},"obj":"Chemical"}],"attributes":[{"id":"A24","pred":"chebi_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A25","pred":"chebi_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_131701"},{"id":"A26","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_33696"},{"id":"A27","pred":"chebi_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"}],"text":"Case 1\nA 57-year-old man living in Wuhan presented with sore throat and fever (39.0 °C) lasting for 3 days. Laboratory testing revealed a white blood cell (WBC) count within the reference range and a slight elevation of high-sensitivity C-reactive protein (hsCRP; 6.65 mg/L, reference range 0–5 mg/L). A search for common respiratory pathogens, including Mycoplasma pneumoniae, Chlamydia pneumoniae, adenovirus, respiratory syncytial virus, and Coxsackie B-virus specific IgM, yielded negative results. A chest CT scan conducted in another hospital 2 days before revealed the presence of a GGO in the right lung, which required further diagnostic workout (differential diagnosis between a tumor and an infectious disease). 18F-FDG PET/CT identified peripheral GGOs with an increased 18F-FDG uptake (SUVmax range 2.2–4.6) in the right upper lung (Fig. 1a, b, arrows) and left lower lung (Fig. 1c; arrows). Unfortunately, SARS-CoV-2 nucleic acid testing was not performed. Antiviral, anti-inflammatory, and symptomatic treatment for 2 weeks led to complete resolution of symptoms.\nFig. 1 Peripheral GGOs with an increased 18F-FDG uptake in the right upper lung and left lower lung"}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T22","span":{"begin":56,"end":67},"obj":"Phenotype"},{"id":"T23","span":{"begin":72,"end":77},"obj":"Phenotype"},{"id":"T24","span":{"begin":366,"end":376},"obj":"Phenotype"},{"id":"T25","span":{"begin":388,"end":398},"obj":"Phenotype"},{"id":"T26","span":{"begin":689,"end":694},"obj":"Phenotype"}],"attributes":[{"id":"A22","pred":"hp_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/HP_0033050"},{"id":"A23","pred":"hp_id","subj":"T23","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A24","pred":"hp_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A25","pred":"hp_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A26","pred":"hp_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/HP_0002664"}],"text":"Case 1\nA 57-year-old man living in Wuhan presented with sore throat and fever (39.0 °C) lasting for 3 days. Laboratory testing revealed a white blood cell (WBC) count within the reference range and a slight elevation of high-sensitivity C-reactive protein (hsCRP; 6.65 mg/L, reference range 0–5 mg/L). A search for common respiratory pathogens, including Mycoplasma pneumoniae, Chlamydia pneumoniae, adenovirus, respiratory syncytial virus, and Coxsackie B-virus specific IgM, yielded negative results. A chest CT scan conducted in another hospital 2 days before revealed the presence of a GGO in the right lung, which required further diagnostic workout (differential diagnosis between a tumor and an infectious disease). 18F-FDG PET/CT identified peripheral GGOs with an increased 18F-FDG uptake (SUVmax range 2.2–4.6) in the right upper lung (Fig. 1a, b, arrows) and left lower lung (Fig. 1c; arrows). Unfortunately, SARS-CoV-2 nucleic acid testing was not performed. Antiviral, anti-inflammatory, and symptomatic treatment for 2 weeks led to complete resolution of symptoms.\nFig. 1 Peripheral GGOs with an increased 18F-FDG uptake in the right upper lung and left lower lung"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T6","span":{"begin":791,"end":797},"obj":"http://purl.obolibrary.org/obo/GO_0098739"},{"id":"T7","span":{"begin":791,"end":797},"obj":"http://purl.obolibrary.org/obo/GO_0098657"},{"id":"T8","span":{"begin":1128,"end":1134},"obj":"http://purl.obolibrary.org/obo/GO_0098739"},{"id":"T9","span":{"begin":1128,"end":1134},"obj":"http://purl.obolibrary.org/obo/GO_0098657"}],"text":"Case 1\nA 57-year-old man living in Wuhan presented with sore throat and fever (39.0 °C) lasting for 3 days. Laboratory testing revealed a white blood cell (WBC) count within the reference range and a slight elevation of high-sensitivity C-reactive protein (hsCRP; 6.65 mg/L, reference range 0–5 mg/L). A search for common respiratory pathogens, including Mycoplasma pneumoniae, Chlamydia pneumoniae, adenovirus, respiratory syncytial virus, and Coxsackie B-virus specific IgM, yielded negative results. A chest CT scan conducted in another hospital 2 days before revealed the presence of a GGO in the right lung, which required further diagnostic workout (differential diagnosis between a tumor and an infectious disease). 18F-FDG PET/CT identified peripheral GGOs with an increased 18F-FDG uptake (SUVmax range 2.2–4.6) in the right upper lung (Fig. 1a, b, arrows) and left lower lung (Fig. 1c; arrows). Unfortunately, SARS-CoV-2 nucleic acid testing was not performed. Antiviral, anti-inflammatory, and symptomatic treatment for 2 weeks led to complete resolution of symptoms.\nFig. 1 Peripheral GGOs with an increased 18F-FDG uptake in the right upper lung and left lower lung"}

{"project":"LitCovid-sentences","denotations":[{"id":"T44","span":{"begin":0,"end":6},"obj":"Sentence"},{"id":"T45","span":{"begin":7,"end":107},"obj":"Sentence"},{"id":"T46","span":{"begin":108,"end":301},"obj":"Sentence"},{"id":"T47","span":{"begin":302,"end":502},"obj":"Sentence"},{"id":"T48","span":{"begin":503,"end":722},"obj":"Sentence"},{"id":"T49","span":{"begin":723,"end":904},"obj":"Sentence"},{"id":"T50","span":{"begin":905,"end":970},"obj":"Sentence"},{"id":"T51","span":{"begin":971,"end":1078},"obj":"Sentence"},{"id":"T52","span":{"begin":1079,"end":1178},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Case 1\nA 57-year-old man living in Wuhan presented with sore throat and fever (39.0 °C) lasting for 3 days. Laboratory testing revealed a white blood cell (WBC) count within the reference range and a slight elevation of high-sensitivity C-reactive protein (hsCRP; 6.65 mg/L, reference range 0–5 mg/L). A search for common respiratory pathogens, including Mycoplasma pneumoniae, Chlamydia pneumoniae, adenovirus, respiratory syncytial virus, and Coxsackie B-virus specific IgM, yielded negative results. A chest CT scan conducted in another hospital 2 days before revealed the presence of a GGO in the right lung, which required further diagnostic workout (differential diagnosis between a tumor and an infectious disease). 18F-FDG PET/CT identified peripheral GGOs with an increased 18F-FDG uptake (SUVmax range 2.2–4.6) in the right upper lung (Fig. 1a, b, arrows) and left lower lung (Fig. 1c; arrows). Unfortunately, SARS-CoV-2 nucleic acid testing was not performed. Antiviral, anti-inflammatory, and symptomatic treatment for 2 weeks led to complete resolution of symptoms.\nFig. 1 Peripheral GGOs with an increased 18F-FDG uptake in the right upper lung and left lower lung"}

{"project":"LitCovid-PubTator","denotations":[{"id":"126","span":{"begin":1097,"end":1101},"obj":"Chemical"},{"id":"127","span":{"begin":1120,"end":1127},"obj":"Chemical"},{"id":"141","span":{"begin":237,"end":255},"obj":"Gene"},{"id":"142","span":{"begin":355,"end":376},"obj":"Species"},{"id":"143","span":{"begin":378,"end":398},"obj":"Species"},{"id":"144","span":{"begin":400,"end":410},"obj":"Species"},{"id":"145","span":{"begin":412,"end":439},"obj":"Species"},{"id":"146","span":{"begin":920,"end":930},"obj":"Species"},{"id":"147","span":{"begin":322,"end":333},"obj":"Species"},{"id":"148","span":{"begin":723,"end":730},"obj":"Chemical"},{"id":"149","span":{"begin":783,"end":790},"obj":"Chemical"},{"id":"150","span":{"begin":56,"end":67},"obj":"Disease"},{"id":"151","span":{"begin":72,"end":77},"obj":"Disease"},{"id":"152","span":{"begin":689,"end":694},"obj":"Disease"},{"id":"153","span":{"begin":702,"end":720},"obj":"Disease"}],"attributes":[{"id":"A127","pred":"tao:has_database_id","subj":"127","obj":"MESH:D019788"},{"id":"A141","pred":"tao:has_database_id","subj":"141","obj":"Gene:1401"},{"id":"A142","pred":"tao:has_database_id","subj":"142","obj":"Tax:2104"},{"id":"A143","pred":"tao:has_database_id","subj":"143","obj":"Tax:83558"},{"id":"A144","pred":"tao:has_database_id","subj":"144","obj":"Tax:10508"},{"id":"A145","pred":"tao:has_database_id","subj":"145","obj":"Tax:12814"},{"id":"A146","pred":"tao:has_database_id","subj":"146","obj":"Tax:2697049"},{"id":"A147","pred":"tao:has_database_id","subj":"147","obj":"Tax:12814"},{"id":"A148","pred":"tao:has_database_id","subj":"148","obj":"MESH:D019788"},{"id":"A149","pred":"tao:has_database_id","subj":"149","obj":"MESH:D019788"},{"id":"A150","pred":"tao:has_database_id","subj":"150","obj":"MESH:D010608"},{"id":"A151","pred":"tao:has_database_id","subj":"151","obj":"MESH:D005334"},{"id":"A152","pred":"tao:has_database_id","subj":"152","obj":"MESH:D009369"},{"id":"A153","pred":"tao:has_database_id","subj":"153","obj":"MESH:D003141"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Case 1\nA 57-year-old man living in Wuhan presented with sore throat and fever (39.0 °C) lasting for 3 days. Laboratory testing revealed a white blood cell (WBC) count within the reference range and a slight elevation of high-sensitivity C-reactive protein (hsCRP; 6.65 mg/L, reference range 0–5 mg/L). A search for common respiratory pathogens, including Mycoplasma pneumoniae, Chlamydia pneumoniae, adenovirus, respiratory syncytial virus, and Coxsackie B-virus specific IgM, yielded negative results. A chest CT scan conducted in another hospital 2 days before revealed the presence of a GGO in the right lung, which required further diagnostic workout (differential diagnosis between a tumor and an infectious disease). 18F-FDG PET/CT identified peripheral GGOs with an increased 18F-FDG uptake (SUVmax range 2.2–4.6) in the right upper lung (Fig. 1a, b, arrows) and left lower lung (Fig. 1c; arrows). Unfortunately, SARS-CoV-2 nucleic acid testing was not performed. Antiviral, anti-inflammatory, and symptomatic treatment for 2 weeks led to complete resolution of symptoms.\nFig. 1 Peripheral GGOs with an increased 18F-FDG uptake in the right upper lung and left lower lung"}