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PMC:7079563 / 22597-24948 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
703 531-540 Species denotes 2019-nCoV Tax:2697049
704 629-638 Species denotes 2019-nCoV Tax:2697049
705 740-749 Species denotes 2019-nCoV Tax:2697049
706 1114-1120 Species denotes People Tax:9606
707 1142-1150 Species denotes Patients Tax:9606
708 1642-1651 Species denotes 2019-nCoV Tax:2697049
709 1789-1794 Species denotes human Tax:9606
710 1795-1803 Species denotes patients Tax:9606
711 1948-1956 Species denotes MERS-CoV Tax:1335626
712 1984-1989 Species denotes mouse Tax:10090
713 1998-2003 Species denotes human Tax:9606
714 2304-2312 Species denotes patients Tax:9606
715 941-950 Chemical denotes lopinavir MESH:D061466
716 1203-1212 Chemical denotes ribavirin MESH:D012254
717 1226-1245 Chemical denotes lopinavir-ritonavir MESH:C558899
718 1680-1690 Chemical denotes remdesivir MESH:C000606551
719 1833-1843 Chemical denotes Remdesivir MESH:C000606551
720 2036-2046 Chemical denotes remdesivir MESH:C000606551
721 75-97 Disease denotes coronavirus infections MESH:D018352
722 1063-1072 Disease denotes pneumonia MESH:D011014
723 1624-1633 Disease denotes infection MESH:D007239
724 1736-1755 Disease denotes 2019-nCoV infection MESH:C000657245
725 1809-1826 Disease denotes 2019-nCoV disease MESH:C000657245
726 2074-2089 Disease denotes virus infection MESH:D001102
727 2162-2182 Disease denotes 2019-nCoV infections MESH:C000657245
728 2215-2224 Disease denotes infection MESH:D007239
729 2289-2303 Disease denotes critically ill MESH:D016638

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T39 791-794 Body_part denotes HIV http://purl.org/sig/ont/fma/fma278683
T40 1920-1923 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T41 1970-1975 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T42 2344-2350 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T20 451-456 Body_part denotes scale http://purl.obolibrary.org/obo/UBERON_0002542

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T77 87-97 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T78 845-849 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T79 1063-1072 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T80 1156-1160 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T81 1497-1499 Disease denotes GS http://purl.obolibrary.org/obo/MONDO_0005773
T82 1624-1633 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T83 1736-1755 Disease denotes 2019-nCoV infection http://purl.obolibrary.org/obo/MONDO_0100096
T84 1746-1755 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T85 1943-1947 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T86 2068-2073 Disease denotes Ebola http://purl.obolibrary.org/obo/MONDO_0005737
T87 2074-2089 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T88 2080-2089 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T89 2162-2182 Disease denotes 2019-nCoV infections http://purl.obolibrary.org/obo/MONDO_0100096
T90 2215-2224 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T164 69-74 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T165 143-144 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T166 254-255 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T167 283-284 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T168 428-429 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T169 510-518 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T170 588-591 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T171 612-620 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T172 721-731 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T173 980-982 http://purl.obolibrary.org/obo/CLO_0053794 denotes 41
T174 1608-1613 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T175 1789-1794 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T176 1828-1830 http://purl.obolibrary.org/obo/CLO_0053799 denotes 45
T177 1844-1847 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T178 1876-1877 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T179 1924-1931 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T180 1961-1975 http://purl.obolibrary.org/obo/CL_0000010 denotes cultured cells
T181 1984-1989 http://purl.obolibrary.org/obo/CLO_0007836 denotes mouse
T182 1998-2003 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T183 2004-2011 http://purl.obolibrary.org/obo/NCBITaxon_9443 denotes primate
T184 2074-2079 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T185 2249-2252 http://purl.obolibrary.org/obo/CL_0000784 denotes IPC
T186 2344-2350 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T38 32-41 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T39 245-250 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T40 344-348 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T41 479-484 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T42 551-555 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T43 577-587 Chemical denotes nelfinavir http://purl.obolibrary.org/obo/CHEBI_7496
T44 602-611 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T45 653-665 Chemical denotes pitavastatin http://purl.obolibrary.org/obo/CHEBI_32020
T46 667-677 Chemical denotes perampanel http://purl.obolibrary.org/obo/CHEBI_71013
T47 683-695 Chemical denotes praziquantel http://purl.obolibrary.org/obo/CHEBI_45267
T48 795-799 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T49 806-813 Chemical denotes Kaletra http://purl.obolibrary.org/obo/CHEBI_145924
T50 885-904 Chemical denotes protease inhibitors http://purl.obolibrary.org/obo/CHEBI_37670|http://purl.obolibrary.org/obo/CHEBI_60258
T52 894-904 Chemical denotes inhibitors http://purl.obolibrary.org/obo/CHEBI_35222
T53 906-915 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T54 941-950 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T55 1019-1026 Chemical denotes Kaletra http://purl.obolibrary.org/obo/CHEBI_145924
T56 1187-1192 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T57 1203-1212 Chemical denotes ribavirin http://purl.obolibrary.org/obo/CHEBI_63580
T58 1214-1224 Chemical denotes interferon http://purl.obolibrary.org/obo/CHEBI_52999
T59 1226-1245 Chemical denotes lopinavir-ritonavir http://purl.obolibrary.org/obo/CHEBI_145924
T60 1226-1235 Chemical denotes lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T61 1236-1245 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T62 1251-1266 Chemical denotes corticosteroids http://purl.obolibrary.org/obo/CHEBI_50858
T63 1296-1301 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T64 1332-1347 Chemical denotes antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044
T65 1332-1341 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T66 1342-1347 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T67 1354-1357 Chemical denotes FAD http://purl.obolibrary.org/obo/CHEBI_16238|http://purl.obolibrary.org/obo/CHEBI_57692|http://purl.obolibrary.org/obo/CHEBI_73627
T70 1367-1372 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T71 1383-1392 Chemical denotes ribavirin http://purl.obolibrary.org/obo/CHEBI_63580
T72 1394-1405 Chemical denotes penciclovir http://purl.obolibrary.org/obo/CHEBI_7956
T73 1430-1441 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T74 1470-1485 Chemical denotes antiviral drugs http://purl.obolibrary.org/obo/CHEBI_36044
T75 1470-1479 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T76 1480-1485 Chemical denotes drugs http://purl.obolibrary.org/obo/CHEBI_23888
T77 1497-1504 Chemical denotes GS-5734 http://purl.obolibrary.org/obo/CHEBI_145994
T78 1497-1499 Chemical denotes GS http://purl.obolibrary.org/obo/CHEBI_73516
T79 1519-1524 Chemical denotes T-705 http://purl.obolibrary.org/obo/CHEBI_134722
T80 1680-1690 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T81 1695-1706 Chemical denotes chloroquine http://purl.obolibrary.org/obo/CHEBI_3638
T82 1888-1902 Chemical denotes antiviral drug http://purl.obolibrary.org/obo/CHEBI_36044
T83 1888-1897 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T84 1898-1902 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T85 2036-2046 Chemical denotes remdesivir http://purl.obolibrary.org/obo/CHEBI_145994
T86 2249-2252 Chemical denotes IPC http://purl.obolibrary.org/obo/CHEBI_53004

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T172 0-98 Sentence denotes There are currently no approved antiviral treatments or vaccines for human coronavirus infections.
T173 99-274 Sentence denotes The development of safe, stable vaccines is a huge challenge and vaccines would ideally be broad-spectrum, so the research and development of new drugs is a very long process.
T174 275-391 Sentence denotes In such a sudden epidemic, scientists were not able to carry out new drug development by the traditional principles.
T175 392-541 Sentence denotes Therefore, there is another option: a systematic and large-scale screening of existing drugs to see whether they have activity against the 2019-nCoV.
T176 542-639 Sentence denotes Recently drug screening found that nelfinavir has potential antiviral activity against 2019-nCoV.
T177 640-755 Sentence denotes In addition, pitavastatin, perampanel, and praziquantel might also have moderate activities against 2019-nCoV [39].
T178 756-922 Sentence denotes Based on previous studies, an anti-HIV drug named Kaletra may have therapeutic effect on SARS and MERS, which is composed of two protease inhibitors, ritonavir (CAS#:
T179 923-957 Sentence denotes 155,213-67-5) and lopinavir (CAS#:
T180 958-1003 Sentence denotes 192,725-17-0) [[40], [41], [42], [43], [44]].
T181 1004-1141 Sentence denotes More recently, Kaletra was also recommended to treat Wuhan pneumonia by the National Health Commission of the People’s Republic of China.
T182 1142-1325 Sentence denotes Patients with SARS or MERS have used several drugs including ribavirin, interferon, lopinavir-ritonavir, and corticosteroids, but the efficacy of certain drugs is still controversial.
T183 1326-1652 Sentence denotes Other antiviral drugs, like FAD-approved drugs including ribavirin, penciclovir, nitrazine, nalfamusta, chloroquine, and the two broad-spectrum antiviral drugs redexivir (GS-5734) and favivir (T-705), are being evaluated by measuring the effects of these compounds on cytotoxicity, virus yield and infection rate of 2019-nCoV.
T184 1653-1832 Sentence denotes Recent results showed that remdesivir and chloroquine are effective in controlling 2019-nCoV infection in vitro and may be evaluated in human patients with 2019-nCoV disease [45].
T185 1833-2025 Sentence denotes Remdesivir has recently been recognized as a promising antiviral drug against multiple RNA viruses (including SARS/MERS-CoV) in cultured cells, and in mouse and non-human primate (NHP) models.
T186 2026-2114 Sentence denotes Currently remdesivir for the treatment of Ebola virus infection is in clinical research.
T187 2115-2183 Sentence denotes It is promising that these compounds can treat 2019-nCoV infections.
T188 2184-2351 Sentence denotes Moreover, the fifth edition of infection prevention and control (IPC) guidance announced that severe and critically ill patients could be treated with recovery plasma.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T27 1063-1072 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090

2_test

Id Subject Object Predicate Lexical cue
32087334-17597972-69695019 974-976 17597972 denotes 40
32087334-14985565-69695020 980-982 14985565 denotes 41
32087334-18706430-69695021 986-988 18706430 denotes 42
32087334-26483999-69695022 992-994 26483999 denotes 43
32087334-29382391-69695023 998-1000 29382391 denotes 44