PMC:7077191 / 21607-22431 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"656","span":{"begin":87,"end":92},"obj":"Gene"},{"id":"657","span":{"begin":94,"end":95},"obj":"Gene"},{"id":"658","span":{"begin":109,"end":110},"obj":"Gene"},{"id":"659","span":{"begin":168,"end":169},"obj":"Gene"},{"id":"660","span":{"begin":309,"end":310},"obj":"Gene"},{"id":"661","span":{"begin":62,"end":70},"obj":"Species"},{"id":"662","span":{"begin":476,"end":484},"obj":"Species"},{"id":"663","span":{"begin":385,"end":394},"obj":"Disease"},{"id":"664","span":{"begin":570,"end":589},"obj":"Disease"},{"id":"665","span":{"begin":648,"end":657},"obj":"Disease"},{"id":"666","span":{"begin":710,"end":725},"obj":"Disease"},{"id":"667","span":{"begin":797,"end":817},"obj":"Disease"}],"attributes":[{"id":"A656","pred":"tao:has_database_id","subj":"656","obj":"Gene:43740568"},{"id":"A657","pred":"tao:has_database_id","subj":"657","obj":"Gene:43740568"},{"id":"A658","pred":"tao:has_database_id","subj":"658","obj":"Gene:43740575"},{"id":"A659","pred":"tao:has_database_id","subj":"659","obj":"Gene:43740575"},{"id":"A660","pred":"tao:has_database_id","subj":"660","obj":"Gene:43740568"},{"id":"A661","pred":"tao:has_database_id","subj":"661","obj":"Tax:694009"},{"id":"A662","pred":"tao:has_database_id","subj":"662","obj":"Tax:694009"},{"id":"A663","pred":"tao:has_database_id","subj":"663","obj":"MESH:D007239"},{"id":"A664","pred":"tao:has_database_id","subj":"664","obj":"MESH:D056647"},{"id":"A665","pred":"tao:has_database_id","subj":"665","obj":"MESH:D007239"},{"id":"A666","pred":"tao:has_database_id","subj":"666","obj":"MESH:D055370"},{"id":"A667","pred":"tao:has_database_id","subj":"667","obj":"MESH:D012128"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Many studies have been performed to study the pathogenesis of SARS-CoV [94,95,96]. The spike (S) protein and N protein confer stability to the viral particle [97]. The N protein is a structural protein involved in virion assembly, and plays a pivotal role in virus transcription and assembly efficiency [97]. S protein can bind to the cellular receptors of sensitive cells and mediate infection of their target cells, after which it begins to replicate in the cytoplasm [98]. SARS-CoV mainly targets the lungs, immune organs, and small systemic blood vessels and causes systemic vasculitis and decrease of immune function [99]. More seriously, the infection leads to extensive pulmonary consolidation, diffuse alveolar damage, and the formation of a transparent membrane, finally deteriorating to respiratory distress [100]."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T59","span":{"begin":97,"end":104},"obj":"Body_part"},{"id":"T60","span":{"begin":111,"end":118},"obj":"Body_part"},{"id":"T61","span":{"begin":170,"end":177},"obj":"Body_part"},{"id":"T62","span":{"begin":194,"end":201},"obj":"Body_part"},{"id":"T63","span":{"begin":311,"end":318},"obj":"Body_part"},{"id":"T64","span":{"begin":367,"end":372},"obj":"Body_part"},{"id":"T65","span":{"begin":411,"end":416},"obj":"Body_part"},{"id":"T66","span":{"begin":460,"end":469},"obj":"Body_part"},{"id":"T67","span":{"begin":504,"end":509},"obj":"Body_part"},{"id":"T68","span":{"begin":545,"end":558},"obj":"Body_part"},{"id":"T69","span":{"begin":545,"end":550},"obj":"Body_part"},{"id":"T70","span":{"begin":710,"end":718},"obj":"Body_part"}],"attributes":[{"id":"A59","pred":"fma_id","subj":"T59","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A60","pred":"fma_id","subj":"T60","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A61","pred":"fma_id","subj":"T61","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A62","pred":"fma_id","subj":"T62","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A63","pred":"fma_id","subj":"T63","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A64","pred":"fma_id","subj":"T64","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A65","pred":"fma_id","subj":"T65","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A66","pred":"fma_id","subj":"T66","obj":"http://purl.org/sig/ont/fma/fma66835"},{"id":"A67","pred":"fma_id","subj":"T67","obj":"http://purl.org/sig/ont/fma/fma68877"},{"id":"A68","pred":"fma_id","subj":"T68","obj":"http://purl.org/sig/ont/fma/fma63183"},{"id":"A69","pred":"fma_id","subj":"T69","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A70","pred":"fma_id","subj":"T70","obj":"http://purl.org/sig/ont/fma/fma264783"}],"text":"Many studies have been performed to study the pathogenesis of SARS-CoV [94,95,96]. The spike (S) protein and N protein confer stability to the viral particle [97]. The N protein is a structural protein involved in virion assembly, and plays a pivotal role in virus transcription and assembly efficiency [97]. S protein can bind to the cellular receptors of sensitive cells and mediate infection of their target cells, after which it begins to replicate in the cytoplasm [98]. SARS-CoV mainly targets the lungs, immune organs, and small systemic blood vessels and causes systemic vasculitis and decrease of immune function [99]. More seriously, the infection leads to extensive pulmonary consolidation, diffuse alveolar damage, and the formation of a transparent membrane, finally deteriorating to respiratory distress [100]."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T17","span":{"begin":511,"end":524},"obj":"Body_part"},{"id":"T18","span":{"begin":518,"end":524},"obj":"Body_part"},{"id":"T19","span":{"begin":545,"end":558},"obj":"Body_part"},{"id":"T20","span":{"begin":545,"end":550},"obj":"Body_part"},{"id":"T21","span":{"begin":551,"end":558},"obj":"Body_part"}],"attributes":[{"id":"A17","pred":"uberon_id","subj":"T17","obj":"http://purl.obolibrary.org/obo/UBERON_0005057"},{"id":"A18","pred":"uberon_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"},{"id":"A19","pred":"uberon_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/UBERON_0001981"},{"id":"A20","pred":"uberon_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A21","pred":"uberon_id","subj":"T21","obj":"http://purl.obolibrary.org/obo/UBERON_0000055"}],"text":"Many studies have been performed to study the pathogenesis of SARS-CoV [94,95,96]. The spike (S) protein and N protein confer stability to the viral particle [97]. The N protein is a structural protein involved in virion assembly, and plays a pivotal role in virus transcription and assembly efficiency [97]. S protein can bind to the cellular receptors of sensitive cells and mediate infection of their target cells, after which it begins to replicate in the cytoplasm [98]. SARS-CoV mainly targets the lungs, immune organs, and small systemic blood vessels and causes systemic vasculitis and decrease of immune function [99]. More seriously, the infection leads to extensive pulmonary consolidation, diffuse alveolar damage, and the formation of a transparent membrane, finally deteriorating to respiratory distress [100]."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T280","span":{"begin":62,"end":70},"obj":"Disease"},{"id":"T281","span":{"begin":62,"end":66},"obj":"Disease"},{"id":"T282","span":{"begin":385,"end":394},"obj":"Disease"},{"id":"T283","span":{"begin":476,"end":484},"obj":"Disease"},{"id":"T284","span":{"begin":476,"end":480},"obj":"Disease"},{"id":"T285","span":{"begin":570,"end":589},"obj":"Disease"},{"id":"T286","span":{"begin":648,"end":657},"obj":"Disease"}],"attributes":[{"id":"A280","pred":"mondo_id","subj":"T280","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A281","pred":"mondo_id","subj":"T281","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A282","pred":"mondo_id","subj":"T282","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A283","pred":"mondo_id","subj":"T283","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A284","pred":"mondo_id","subj":"T284","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A285","pred":"mondo_id","subj":"T285","obj":"http://purl.obolibrary.org/obo/MONDO_0018882"},{"id":"A286","pred":"mondo_id","subj":"T286","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":"Many studies have been performed to study the pathogenesis of SARS-CoV [94,95,96]. The spike (S) protein and N protein confer stability to the viral particle [97]. The N protein is a structural protein involved in virion assembly, and plays a pivotal role in virus transcription and assembly efficiency [97]. S protein can bind to the cellular receptors of sensitive cells and mediate infection of their target cells, after which it begins to replicate in the cytoplasm [98]. SARS-CoV mainly targets the lungs, immune organs, and small systemic blood vessels and causes systemic vasculitis and decrease of immune function [99]. More seriously, the infection leads to extensive pulmonary consolidation, diffuse alveolar damage, and the formation of a transparent membrane, finally deteriorating to respiratory distress [100]."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T202","span":{"begin":181,"end":182},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T203","span":{"begin":241,"end":242},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T204","span":{"begin":259,"end":264},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T205","span":{"begin":367,"end":372},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T206","span":{"begin":411,"end":416},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T207","span":{"begin":504,"end":509},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T208","span":{"begin":518,"end":524},"obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"T209","span":{"begin":545,"end":558},"obj":"http://purl.obolibrary.org/obo/UBERON_0001981"},{"id":"T210","span":{"begin":545,"end":558},"obj":"http://www.ebi.ac.uk/efo/EFO_0000817"},{"id":"T211","span":{"begin":748,"end":749},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T212","span":{"begin":762,"end":770},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"}],"text":"Many studies have been performed to study the pathogenesis of SARS-CoV [94,95,96]. The spike (S) protein and N protein confer stability to the viral particle [97]. The N protein is a structural protein involved in virion assembly, and plays a pivotal role in virus transcription and assembly efficiency [97]. S protein can bind to the cellular receptors of sensitive cells and mediate infection of their target cells, after which it begins to replicate in the cytoplasm [98]. SARS-CoV mainly targets the lungs, immune organs, and small systemic blood vessels and causes systemic vasculitis and decrease of immune function [99]. More seriously, the infection leads to extensive pulmonary consolidation, diffuse alveolar damage, and the formation of a transparent membrane, finally deteriorating to respiratory distress [100]."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T98","span":{"begin":97,"end":104},"obj":"Chemical"},{"id":"T99","span":{"begin":111,"end":118},"obj":"Chemical"},{"id":"T100","span":{"begin":170,"end":177},"obj":"Chemical"},{"id":"T101","span":{"begin":194,"end":201},"obj":"Chemical"},{"id":"T102","span":{"begin":311,"end":318},"obj":"Chemical"}],"attributes":[{"id":"A98","pred":"chebi_id","subj":"T98","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A99","pred":"chebi_id","subj":"T99","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A100","pred":"chebi_id","subj":"T100","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A101","pred":"chebi_id","subj":"T101","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A102","pred":"chebi_id","subj":"T102","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"Many studies have been performed to study the pathogenesis of SARS-CoV [94,95,96]. The spike (S) protein and N protein confer stability to the viral particle [97]. The N protein is a structural protein involved in virion assembly, and plays a pivotal role in virus transcription and assembly efficiency [97]. S protein can bind to the cellular receptors of sensitive cells and mediate infection of their target cells, after which it begins to replicate in the cytoplasm [98]. SARS-CoV mainly targets the lungs, immune organs, and small systemic blood vessels and causes systemic vasculitis and decrease of immune function [99]. More seriously, the infection leads to extensive pulmonary consolidation, diffuse alveolar damage, and the formation of a transparent membrane, finally deteriorating to respiratory distress [100]."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T35","span":{"begin":579,"end":589},"obj":"Phenotype"},{"id":"T36","span":{"begin":594,"end":621},"obj":"Phenotype"},{"id":"T37","span":{"begin":702,"end":725},"obj":"Phenotype"},{"id":"T38","span":{"begin":797,"end":817},"obj":"Phenotype"}],"attributes":[{"id":"A35","pred":"hp_id","subj":"T35","obj":"http://purl.obolibrary.org/obo/HP_0002633"},{"id":"A36","pred":"hp_id","subj":"T36","obj":"http://purl.obolibrary.org/obo/HP_0002721"},{"id":"A37","pred":"hp_id","subj":"T37","obj":"http://purl.obolibrary.org/obo/HP_0033006"},{"id":"A38","pred":"hp_id","subj":"T38","obj":"http://purl.obolibrary.org/obo/HP_0002098"}],"text":"Many studies have been performed to study the pathogenesis of SARS-CoV [94,95,96]. The spike (S) protein and N protein confer stability to the viral particle [97]. The N protein is a structural protein involved in virion assembly, and plays a pivotal role in virus transcription and assembly efficiency [97]. S protein can bind to the cellular receptors of sensitive cells and mediate infection of their target cells, after which it begins to replicate in the cytoplasm [98]. SARS-CoV mainly targets the lungs, immune organs, and small systemic blood vessels and causes systemic vasculitis and decrease of immune function [99]. More seriously, the infection leads to extensive pulmonary consolidation, diffuse alveolar damage, and the formation of a transparent membrane, finally deteriorating to respiratory distress [100]."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T7","span":{"begin":46,"end":58},"obj":"http://purl.obolibrary.org/obo/GO_0009405"},{"id":"T8","span":{"begin":214,"end":229},"obj":"http://purl.obolibrary.org/obo/GO_0019068"},{"id":"T9","span":{"begin":265,"end":278},"obj":"http://purl.obolibrary.org/obo/GO_0006351"},{"id":"T10","span":{"begin":735,"end":744},"obj":"http://purl.obolibrary.org/obo/GO_0009058"}],"text":"Many studies have been performed to study the pathogenesis of SARS-CoV [94,95,96]. The spike (S) protein and N protein confer stability to the viral particle [97]. The N protein is a structural protein involved in virion assembly, and plays a pivotal role in virus transcription and assembly efficiency [97]. S protein can bind to the cellular receptors of sensitive cells and mediate infection of their target cells, after which it begins to replicate in the cytoplasm [98]. SARS-CoV mainly targets the lungs, immune organs, and small systemic blood vessels and causes systemic vasculitis and decrease of immune function [99]. More seriously, the infection leads to extensive pulmonary consolidation, diffuse alveolar damage, and the formation of a transparent membrane, finally deteriorating to respiratory distress [100]."}

{"project":"LitCovid-sentences","denotations":[{"id":"T199","span":{"begin":0,"end":82},"obj":"Sentence"},{"id":"T200","span":{"begin":83,"end":163},"obj":"Sentence"},{"id":"T201","span":{"begin":164,"end":308},"obj":"Sentence"},{"id":"T202","span":{"begin":309,"end":475},"obj":"Sentence"},{"id":"T203","span":{"begin":476,"end":627},"obj":"Sentence"},{"id":"T204","span":{"begin":628,"end":824},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Many studies have been performed to study the pathogenesis of SARS-CoV [94,95,96]. The spike (S) protein and N protein confer stability to the viral particle [97]. The N protein is a structural protein involved in virion assembly, and plays a pivotal role in virus transcription and assembly efficiency [97]. S protein can bind to the cellular receptors of sensitive cells and mediate infection of their target cells, after which it begins to replicate in the cytoplasm [98]. SARS-CoV mainly targets the lungs, immune organs, and small systemic blood vessels and causes systemic vasculitis and decrease of immune function [99]. More seriously, the infection leads to extensive pulmonary consolidation, diffuse alveolar damage, and the formation of a transparent membrane, finally deteriorating to respiratory distress [100]."}

{"project":"2_test","denotations":[{"id":"32098422-15018126-144407019","span":{"begin":72,"end":74},"obj":"15018126"},{"id":"32098422-17031779-144407020","span":{"begin":75,"end":77},"obj":"17031779"},{"id":"32098422-15141377-144407021","span":{"begin":78,"end":80},"obj":"15141377"},{"id":"32098422-19430490-144407022","span":{"begin":159,"end":161},"obj":"19430490"},{"id":"32098422-19430490-144407023","span":{"begin":304,"end":306},"obj":"19430490"},{"id":"32098422-12845623-144407024","span":{"begin":471,"end":473},"obj":"12845623"},{"id":"32098422-15141376-144407025","span":{"begin":623,"end":625},"obj":"15141376"},{"id":"32098422-15018129-144407026","span":{"begin":819,"end":822},"obj":"15018129"}],"text":"Many studies have been performed to study the pathogenesis of SARS-CoV [94,95,96]. The spike (S) protein and N protein confer stability to the viral particle [97]. The N protein is a structural protein involved in virion assembly, and plays a pivotal role in virus transcription and assembly efficiency [97]. S protein can bind to the cellular receptors of sensitive cells and mediate infection of their target cells, after which it begins to replicate in the cytoplasm [98]. SARS-CoV mainly targets the lungs, immune organs, and small systemic blood vessels and causes systemic vasculitis and decrease of immune function [99]. More seriously, the infection leads to extensive pulmonary consolidation, diffuse alveolar damage, and the formation of a transparent membrane, finally deteriorating to respiratory distress [100]."}