PMC:7075884 / 2572-2897 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"139","span":{"begin":168,"end":172},"obj":"Gene"},{"id":"140","span":{"begin":205,"end":214},"obj":"Gene"},{"id":"141","span":{"begin":216,"end":218},"obj":"Gene"},{"id":"145","span":{"begin":0,"end":2},"obj":"Chemical"}],"attributes":[{"id":"A139","pred":"tao:has_database_id","subj":"139","obj":"Gene:5564"},{"id":"A140","pred":"tao:has_database_id","subj":"140","obj":"Gene:351"},{"id":"A141","pred":"tao:has_database_id","subj":"141","obj":"Gene:351"},{"id":"A145","pred":"tao:has_database_id","subj":"145","obj":"MESH:C112485"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"GA has shown pleiotropic effects in vitro, including: antitumor effects through inhibition of lipogenesis; decreased expression of invasion associated proteins through AMPK activation; potential rescue of amyloid-β (Aβ) induced synaptic impairment; and inhibition of HIV protease activity as well as HIV viral replication4–7."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T11","span":{"begin":151,"end":159},"obj":"Body_part"},{"id":"T12","span":{"begin":267,"end":270},"obj":"Body_part"},{"id":"T13","span":{"begin":300,"end":303},"obj":"Body_part"}],"attributes":[{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A12","pred":"fma_id","subj":"T12","obj":"http://purl.org/sig/ont/fma/fma278683"},{"id":"A13","pred":"fma_id","subj":"T13","obj":"http://purl.org/sig/ont/fma/fma278683"}],"text":"GA has shown pleiotropic effects in vitro, including: antitumor effects through inhibition of lipogenesis; decreased expression of invasion associated proteins through AMPK activation; potential rescue of amyloid-β (Aβ) induced synaptic impairment; and inhibition of HIV protease activity as well as HIV viral replication4–7."}

{"project":"LitCovid_AGAC","denotations":[{"id":"p19178s17","span":{"begin":107,"end":116},"obj":"NegReg"},{"id":"p19178s18","span":{"begin":117,"end":127},"obj":"MPA"}],"text":"GA has shown pleiotropic effects in vitro, including: antitumor effects through inhibition of lipogenesis; decreased expression of invasion associated proteins through AMPK activation; potential rescue of amyloid-β (Aβ) induced synaptic impairment; and inhibition of HIV protease activity as well as HIV viral replication4–7."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T15","span":{"begin":205,"end":212},"obj":"Disease"}],"attributes":[{"id":"A15","pred":"mondo_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/MONDO_0019065"}],"text":"GA has shown pleiotropic effects in vitro, including: antitumor effects through inhibition of lipogenesis; decreased expression of invasion associated proteins through AMPK activation; potential rescue of amyloid-β (Aβ) induced synaptic impairment; and inhibition of HIV protease activity as well as HIV viral replication4–7."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T28","span":{"begin":3,"end":6},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T29","span":{"begin":173,"end":183},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T30","span":{"begin":216,"end":217},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T31","span":{"begin":280,"end":288},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"}],"text":"GA has shown pleiotropic effects in vitro, including: antitumor effects through inhibition of lipogenesis; decreased expression of invasion associated proteins through AMPK activation; potential rescue of amyloid-β (Aβ) induced synaptic impairment; and inhibition of HIV protease activity as well as HIV viral replication4–7."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T63","span":{"begin":0,"end":2},"obj":"Chemical"},{"id":"T66","span":{"begin":151,"end":159},"obj":"Chemical"}],"attributes":[{"id":"A63","pred":"chebi_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/CHEBI_5206"},{"id":"A64","pred":"chebi_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/CHEBI_73855"},{"id":"A65","pred":"chebi_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/CHEBI_5354"},{"id":"A66","pred":"chebi_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"GA has shown pleiotropic effects in vitro, including: antitumor effects through inhibition of lipogenesis; decreased expression of invasion associated proteins through AMPK activation; potential rescue of amyloid-β (Aβ) induced synaptic impairment; and inhibition of HIV protease activity as well as HIV viral replication4–7."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T14","span":{"begin":94,"end":105},"obj":"http://purl.obolibrary.org/obo/GO_0008610"},{"id":"T15","span":{"begin":168,"end":172},"obj":"http://purl.obolibrary.org/obo/GO_0050405"},{"id":"T16","span":{"begin":168,"end":172},"obj":"http://purl.obolibrary.org/obo/GO_0047322"},{"id":"T17","span":{"begin":168,"end":172},"obj":"http://purl.obolibrary.org/obo/GO_0004691"},{"id":"T18","span":{"begin":271,"end":288},"obj":"http://purl.obolibrary.org/obo/GO_0008233"}],"text":"GA has shown pleiotropic effects in vitro, including: antitumor effects through inhibition of lipogenesis; decreased expression of invasion associated proteins through AMPK activation; potential rescue of amyloid-β (Aβ) induced synaptic impairment; and inhibition of HIV protease activity as well as HIV viral replication4–7."}

{"project":"LitCovid-sentences","denotations":[{"id":"T21","span":{"begin":0,"end":325},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"GA has shown pleiotropic effects in vitro, including: antitumor effects through inhibition of lipogenesis; decreased expression of invasion associated proteins through AMPK activation; potential rescue of amyloid-β (Aβ) induced synaptic impairment; and inhibition of HIV protease activity as well as HIV viral replication4–7."}

{"project":"2_test","denotations":[{"id":"32179788-25895130-138463418","span":{"begin":321,"end":322},"obj":"25895130"},{"id":"32179788-29113214-138463418","span":{"begin":321,"end":322},"obj":"29113214"},{"id":"32179788-27833555-138463418","span":{"begin":321,"end":322},"obj":"27833555"},{"id":"32179788-22847190-138463418","span":{"begin":321,"end":322},"obj":"22847190"}],"text":"GA has shown pleiotropic effects in vitro, including: antitumor effects through inhibition of lipogenesis; decreased expression of invasion associated proteins through AMPK activation; potential rescue of amyloid-β (Aβ) induced synaptic impairment; and inhibition of HIV protease activity as well as HIV viral replication4–7."}