PMC:7075884 / 23460-24326 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7075884","sourcedb":"PMC","sourceid":"7075884","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7075884","text":"Viral protein synthesis was determined in HSV-infected cells following GA treatment. Untreated HEp-2 and 293T cells were infected with HSV-1 F’ at an MOI of 1 for 2 hours, allowing the virions to internalize into the cells, then washed with 199V medium and supplemented with 10 µM GA or vehicle. The viral replication was evaluated by Western Blot detection of HSV-1 proteins. Although the infection of HEp-2 and 293T cells had been initiated, the addition of 10 µM GA to the infected HEp-2 and 293T cells inhibited the virus replication from the point of exposure to GA (Fig. 7B,C). The observed effect could be the result of inhibition of secondary infections. 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