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PMC:7075884 / 23460-24326 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
854 135-140 Species denotes HSV-1 Tax:10298
855 361-366 Species denotes HSV-1 Tax:10298
856 71-73 Chemical denotes GA MESH:C112485
857 466-468 Chemical denotes GA MESH:C112485
858 568-570 Chemical denotes GA MESH:C112485
859 42-54 Disease denotes HSV-infected MESH:C536395
860 121-129 Disease denotes infected MESH:D007239
861 390-399 Disease denotes infection MESH:D007239
862 476-484 Disease denotes infected MESH:D007239
863 641-661 Disease denotes secondary infections MESH:D060085
864 95-100 CellLine denotes HEp-2 CVCL:1906
865 105-109 CellLine denotes 293T CVCL:0063
866 403-408 CellLine denotes HEp-2 CVCL:1906
867 413-417 CellLine denotes 293T CVCL:0063
868 485-490 CellLine denotes HEp-2 CVCL:1906
869 495-499 CellLine denotes 293T CVCL:0063

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T185 6-13 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T186 55-60 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T187 110-115 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T188 217-222 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T189 367-375 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T190 418-423 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T191 500-505 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T192 705-713 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T193 848-855 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T59 390-399 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T60 651-661 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T356 55-60 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T357 95-100 http://purl.obolibrary.org/obo/CLO_0003707 denotes HEp-2
T358 95-100 http://purl.obolibrary.org/obo/CLO_0050927 denotes HEp-2
T359 105-109 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T360 105-109 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T361 105-109 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T362 110-115 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T363 217-222 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T364 403-408 http://purl.obolibrary.org/obo/CLO_0003707 denotes HEp-2
T365 403-408 http://purl.obolibrary.org/obo/CLO_0050927 denotes HEp-2
T366 413-417 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T367 413-417 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T368 413-417 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T369 418-423 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T370 485-490 http://purl.obolibrary.org/obo/CLO_0003707 denotes HEp-2
T371 485-490 http://purl.obolibrary.org/obo/CLO_0050927 denotes HEp-2
T372 495-499 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T373 495-499 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T374 495-499 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T375 500-505 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T376 520-525 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T377 734-735 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T378 799-800 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T602 6-13 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T603 71-73 Chemical denotes GA http://purl.obolibrary.org/obo/CHEBI_5206|http://purl.obolibrary.org/obo/CHEBI_73855|http://purl.obolibrary.org/obo/CHEBI_5354
T606 281-283 Chemical denotes GA http://purl.obolibrary.org/obo/CHEBI_5206|http://purl.obolibrary.org/obo/CHEBI_73855|http://purl.obolibrary.org/obo/CHEBI_5354
T609 367-375 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T610 466-468 Chemical denotes GA http://purl.obolibrary.org/obo/CHEBI_5206|http://purl.obolibrary.org/obo/CHEBI_73855|http://purl.obolibrary.org/obo/CHEBI_5354
T613 568-570 Chemical denotes GA http://purl.obolibrary.org/obo/CHEBI_5206|http://purl.obolibrary.org/obo/CHEBI_73855|http://purl.obolibrary.org/obo/CHEBI_5354
T616 705-713 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T617 848-855 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T102 0-23 http://purl.obolibrary.org/obo/GO_0019081 denotes Viral protein synthesis
T103 6-23 http://purl.obolibrary.org/obo/GO_0006412 denotes protein synthesis
T104 14-23 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T105 300-317 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T106 300-317 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T107 687-697 http://purl.obolibrary.org/obo/GO_0065007 denotes regulation
T108 745-762 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T109 745-762 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T110 842-865 http://purl.obolibrary.org/obo/GO_0019081 denotes viral protein synthesis
T111 848-865 http://purl.obolibrary.org/obo/GO_0006412 denotes protein synthesis
T112 856-865 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T169 0-84 Sentence denotes Viral protein synthesis was determined in HSV-infected cells following GA treatment.
T170 85-295 Sentence denotes Untreated HEp-2 and 293T cells were infected with HSV-1 F’ at an MOI of 1 for 2 hours, allowing the virions to internalize into the cells, then washed with 199V medium and supplemented with 10 µM GA or vehicle.
T171 296-376 Sentence denotes The viral replication was evaluated by Western Blot detection of HSV-1 proteins.
T172 377-583 Sentence denotes Although the infection of HEp-2 and 293T cells had been initiated, the addition of 10 µM GA to the infected HEp-2 and 293T cells inhibited the virus replication from the point of exposure to GA (Fig. 7B,C).
T173 584-662 Sentence denotes The observed effect could be the result of inhibition of secondary infections.
T174 663-866 Sentence denotes However, the early down regulation of HSV proteins, occurring prior to a complete viral replication cycle, suggests that there could be a secondary inhibitory mechanism targeting viral protein synthesis.