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PMC:7075884 / 14769-16162 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
595 1191-1198 Gene denotes dE1/E3) Gene:45300
596 1272-1275 Gene denotes C15 Gene:51316
597 1088-1091 Gene denotes C15 Gene:51316
598 886-889 Gene denotes C15 Gene:51316
599 771-774 Gene denotes C15 Gene:51316
600 666-687 Species denotes human adenovirus. (A) Tax:129875
601 827-832 Species denotes HSV-1 Tax:10298
602 1166-1189 Species denotes human adenovirus type 5 Tax:28285
603 640-642 Chemical denotes GA MESH:C112485
604 780-784 Chemical denotes DMSO MESH:D004121
605 1097-1101 Chemical denotes DMSO MESH:D004121
606 809-817 Disease denotes infected MESH:D007239
607 906-915 Disease denotes Infection MESH:D007239
618 333-340 Gene denotes dE1/E3) Gene:45300
619 434-437 Gene denotes C15 Gene:51316
620 225-228 Gene denotes C15 Gene:51316
621 92-102 Species denotes adenovirus Tax:10508
622 308-331 Species denotes human adenovirus type 5 Tax:28285
623 372-377 Species denotes HSV-1 Tax:10298
624 563-568 Species denotes HSV-1 Tax:10298
625 619-629 Species denotes adenovirus Tax:10508
626 24-26 Chemical denotes GA MESH:C112485
627 234-238 Chemical denotes DMSO MESH:D004121

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T105 161-166 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T106 252-257 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T107 474-479 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T108 707-712 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T109 798-803 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T110 1021-1026 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T111 1115-1120 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T51 906-915 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T223 44-49 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T224 59-65 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T225 80-88 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T226 156-160 http://purl.obolibrary.org/obo/CLO_0009524 denotes Vero
T227 156-160 http://purl.obolibrary.org/obo/CLO_0050515 denotes Vero
T228 161-166 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T229 252-257 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T230 284-285 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T231 308-313 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T232 337-339 http://purl.obolibrary.org/obo/CLO_0002861 denotes E3
T233 352-355 http://purl.obolibrary.org/obo/CLO_0053478 denotes GFP
T234 360-363 http://purl.obolibrary.org/obo/CLO_0053478 denotes GFP
T235 368-371 http://purl.obolibrary.org/obo/CLO_0053478 denotes GFP
T236 378-383 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T237 405-406 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T238 469-473 http://purl.obolibrary.org/obo/CLO_0009524 denotes Vero
T239 469-473 http://purl.obolibrary.org/obo/CLO_0050515 denotes Vero
T240 474-479 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T241 666-671 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T242 685-686 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T243 702-706 http://purl.obolibrary.org/obo/CLO_0009524 denotes Vero
T244 702-706 http://purl.obolibrary.org/obo/CLO_0050515 denotes Vero
T245 707-712 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T246 798-803 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T247 823-826 http://purl.obolibrary.org/obo/CLO_0053478 denotes GFP
T248 833-838 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T249 999-1000 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T250 1016-1020 http://purl.obolibrary.org/obo/CLO_0009524 denotes Vero
T251 1016-1020 http://purl.obolibrary.org/obo/CLO_0050515 denotes Vero
T252 1021-1026 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T253 1115-1120 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T254 1142-1143 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T255 1166-1171 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T256 1195-1197 http://purl.obolibrary.org/obo/CLO_0002861 denotes E3
T257 1210-1213 http://purl.obolibrary.org/obo/CLO_0053478 denotes GFP
T258 1218-1221 http://purl.obolibrary.org/obo/CLO_0053478 denotes GFP
T259 1243-1244 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T330 24-26 Chemical denotes GA http://purl.obolibrary.org/obo/CHEBI_5206|http://purl.obolibrary.org/obo/CHEBI_73855|http://purl.obolibrary.org/obo/CHEBI_5354
T333 70-79 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T334 222-224 Chemical denotes GA http://purl.obolibrary.org/obo/CHEBI_5206|http://purl.obolibrary.org/obo/CHEBI_73855|http://purl.obolibrary.org/obo/CHEBI_5354
T337 225-230 Chemical denotes C15:1 http://purl.obolibrary.org/obo/CHEBI_75088
T338 225-228 Chemical denotes C15 http://purl.obolibrary.org/obo/CHEBI_42504
T339 234-238 Chemical denotes DMSO http://purl.obolibrary.org/obo/CHEBI_28262
T340 431-433 Chemical denotes GA http://purl.obolibrary.org/obo/CHEBI_5206|http://purl.obolibrary.org/obo/CHEBI_73855|http://purl.obolibrary.org/obo/CHEBI_5354
T343 434-439 Chemical denotes C15:1 http://purl.obolibrary.org/obo/CHEBI_75088
T344 434-437 Chemical denotes C15 http://purl.obolibrary.org/obo/CHEBI_42504
T345 640-642 Chemical denotes GA http://purl.obolibrary.org/obo/CHEBI_5206|http://purl.obolibrary.org/obo/CHEBI_73855|http://purl.obolibrary.org/obo/CHEBI_5354
T348 768-770 Chemical denotes GA http://purl.obolibrary.org/obo/CHEBI_5206|http://purl.obolibrary.org/obo/CHEBI_73855|http://purl.obolibrary.org/obo/CHEBI_5354
T351 771-776 Chemical denotes C15:1 http://purl.obolibrary.org/obo/CHEBI_75088
T352 771-774 Chemical denotes C15 http://purl.obolibrary.org/obo/CHEBI_42504
T353 780-784 Chemical denotes DMSO http://purl.obolibrary.org/obo/CHEBI_28262
T354 883-885 Chemical denotes GA http://purl.obolibrary.org/obo/CHEBI_5206|http://purl.obolibrary.org/obo/CHEBI_73855|http://purl.obolibrary.org/obo/CHEBI_5354
T357 886-891 Chemical denotes C15:1 http://purl.obolibrary.org/obo/CHEBI_75088
T358 886-889 Chemical denotes C15 http://purl.obolibrary.org/obo/CHEBI_42504
T359 1085-1087 Chemical denotes GA http://purl.obolibrary.org/obo/CHEBI_5206|http://purl.obolibrary.org/obo/CHEBI_73855|http://purl.obolibrary.org/obo/CHEBI_5354
T362 1088-1093 Chemical denotes C15:1 http://purl.obolibrary.org/obo/CHEBI_75088
T363 1088-1091 Chemical denotes C15 http://purl.obolibrary.org/obo/CHEBI_42504
T364 1097-1101 Chemical denotes DMSO http://purl.obolibrary.org/obo/CHEBI_28262
T365 1269-1271 Chemical denotes GA http://purl.obolibrary.org/obo/CHEBI_5206|http://purl.obolibrary.org/obo/CHEBI_73855|http://purl.obolibrary.org/obo/CHEBI_5354
T368 1272-1277 Chemical denotes C15:1 http://purl.obolibrary.org/obo/CHEBI_75088
T369 1272-1275 Chemical denotes C15 http://purl.obolibrary.org/obo/CHEBI_42504

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T37 129-140 http://purl.obolibrary.org/obo/GO_0006897 denotes endocytosis

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T99 0-141 Sentence denotes To assess the effect of GA on non-enveloped virus, we also tested its antiviral activity on adenovirus, which is internalized by endocytosis.
T100 142-247 Sentence denotes Monolayers of Vero cells were incubated for 1 hour with medium containing 10 µM GA C15:1 or DMSO vehicle.
T101 248-453 Sentence denotes The cells then were inoculated with a replication-defective human adenovirus type 5 (dE1/E3) containing GFP (Ad-GFP) or GFP-HSV-1 virus, at an MOI of 0.5 in a medium containing 10 µM GA C15:1 for 24 hours.
T102 454-531 Sentence denotes The inoculated Vero cells were evaluated by fluorescence microscopy (Fig. 4).
T103 532-630 Sentence denotes The results showed significant HSV-1 inhibition, as well as inhibition of entry of the adenovirus.
T104 631-793 Sentence denotes Figure 4 GA inhibits non-enveloped human adenovirus. (A) Monolayers of Vero cells were incubated for 1 hour with medium containing 10 µM GA C15:1 or DMSO vehicle.
T105 794-905 Sentence denotes The cells were infected with GFP-HSV-1 virus at an MOI of 0.5 in medium containing 10 µM GA C15:1 for 24 hours.
T106 906-1110 Sentence denotes Infection was evaluated by light (lower panels) and fluorescence (upper panels) microscopy. (B) Monolayers of Vero cells were incubated for 1 hour with medium containing 10 µM of GA C15:1 or DMSO vehicle.
T107 1111-1291 Sentence denotes The cells were inoculated with a replication-defective human adenovirus type 5 (dE1/E3) containing GFP (Ad-GFP) at an MOI of 0.5 in a medium containing 10 µM GA C15:1 for 24 hours.
T108 1292-1393 Sentence denotes Inhibition of entry was evaluated by light (lower panels) and fluorescence (upper panels) microscopy.