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LitCovid-PubTator

LitCovid-PD-FMA-UBERON

LitCovid-PD-UBERON

LitCovid_AGAC

{"project":"LitCovid_AGAC","denotations":[{"id":"p19106s18","span":{"begin":2107,"end":2115},"obj":"NegReg"}],"text":"Chest CT examination is very important in the initial diagnosis of the new type of pneumonia, and CT changes are variable. By collecting chest CT of patients with 2019-nCov related pneumonia in our hospital, we summarized the common imaging changes of the patients. CT is often found to be positive when patients with 2019-nCoV develop persistent fever, cough, and unexplained weakness. Early CT lung manifestations are diverse: they may be lung ground glass shadow (Fig. 1a–c), pulmonary consolidation and nodules (Fig. 1d), and local consolidation in the center with ground glass density around (Fig. 1e). Depending on the course of the disease, pneumonia may involve one or more lobes simultaneously (Fig. 1a, c, g). When one or two lobes are involved, the effect on lung function is not serious, and the symptoms of shortness of breath and dyspnea are not severe. As the disease progresses, the consolidation area of the lung begins to absorb, reducing its density and gradually becoming a ground glass opacity, like “melted sugar” (Fig. 1f). At this point, if the patient receives effective treatment or if immunity successfully fights against the virus, the inflammation will be further absorbed and the extent will be minimized. The disease will improve, perhaps leaving the lung fiber cord focus (Fig. 1g). This very much resembles a bout of flu. If the treatment is not received promptly or if immunity fails to fight off the virus, in time, it becomes life-threatening. Lung can progress to a \"white lung\" appearance (Fig. 1h), however, this is only seen in a very small number of patients with diffuse alveolar damage involving multiple lobes. At this stage, the ventilation function will be seriously impaired, requiring continuous oxygen inhalation, and even extracorporeal membrane pulmonary oxygenation (ECMO).\nFigure 1. CT images of 2019-nCoV related pneumonia.a–c. ground glass opacities; (d) pulmonary consolidation and nodules; (e) local consolidation in the center with peripheral ground glass opacity; (f) as the disease progresses, the consolidation area of the lung begins to absorb, reducing its density and gradually becoming ground glass opacity, like a “melted sugar”; (g) the inflammation has absorbed, leaving the lung fiber cord focus; (h) the pneumonia deteriorated and the lungs progressed to the “white lung” stage"}

LitCovid-PD-MONDO

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T7","span":{"begin":83,"end":92},"obj":"Disease"},{"id":"T8","span":{"begin":181,"end":190},"obj":"Disease"},{"id":"T9","span":{"begin":648,"end":657},"obj":"Disease"},{"id":"T10","span":{"begin":1164,"end":1176},"obj":"Disease"},{"id":"T11","span":{"begin":1350,"end":1353},"obj":"Disease"},{"id":"T12","span":{"begin":2204,"end":2216},"obj":"Disease"},{"id":"T13","span":{"begin":2274,"end":2283},"obj":"Disease"}],"attributes":[{"id":"A7","pred":"mondo_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A10","pred":"mondo_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A11","pred":"mondo_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A12","pred":"mondo_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"},{"id":"A13","pred":"mondo_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"}],"text":"Chest CT examination is very important in the initial diagnosis of the new type of pneumonia, and CT changes are variable. By collecting chest CT of patients with 2019-nCov related pneumonia in our hospital, we summarized the common imaging changes of the patients. CT is often found to be positive when patients with 2019-nCoV develop persistent fever, cough, and unexplained weakness. Early CT lung manifestations are diverse: they may be lung ground glass shadow (Fig. 1a–c), pulmonary consolidation and nodules (Fig. 1d), and local consolidation in the center with ground glass density around (Fig. 1e). Depending on the course of the disease, pneumonia may involve one or more lobes simultaneously (Fig. 1a, c, g). When one or two lobes are involved, the effect on lung function is not serious, and the symptoms of shortness of breath and dyspnea are not severe. As the disease progresses, the consolidation area of the lung begins to absorb, reducing its density and gradually becoming a ground glass opacity, like “melted sugar” (Fig. 1f). At this point, if the patient receives effective treatment or if immunity successfully fights against the virus, the inflammation will be further absorbed and the extent will be minimized. The disease will improve, perhaps leaving the lung fiber cord focus (Fig. 1g). This very much resembles a bout of flu. If the treatment is not received promptly or if immunity fails to fight off the virus, in time, it becomes life-threatening. Lung can progress to a \"white lung\" appearance (Fig. 1h), however, this is only seen in a very small number of patients with diffuse alveolar damage involving multiple lobes. At this stage, the ventilation function will be seriously impaired, requiring continuous oxygen inhalation, and even extracorporeal membrane pulmonary oxygenation (ECMO).\nFigure 1. CT images of 2019-nCoV related pneumonia.a–c. ground glass opacities; (d) pulmonary consolidation and nodules; (e) local consolidation in the center with peripheral ground glass opacity; (f) as the disease progresses, the consolidation area of the lung begins to absorb, reducing its density and gradually becoming ground glass opacity, like a “melted sugar”; (g) the inflammation has absorbed, leaving the lung fiber cord focus; (h) the pneumonia deteriorated and the lungs progressed to the “white lung” stage"}

LitCovid-PD-CLO

LitCovid-PD-CHEBI

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T6","span":{"begin":1744,"end":1750},"obj":"Chemical"}],"attributes":[{"id":"A6","pred":"chebi_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"}],"text":"Chest CT examination is very important in the initial diagnosis of the new type of pneumonia, and CT changes are variable. By collecting chest CT of patients with 2019-nCov related pneumonia in our hospital, we summarized the common imaging changes of the patients. CT is often found to be positive when patients with 2019-nCoV develop persistent fever, cough, and unexplained weakness. Early CT lung manifestations are diverse: they may be lung ground glass shadow (Fig. 1a–c), pulmonary consolidation and nodules (Fig. 1d), and local consolidation in the center with ground glass density around (Fig. 1e). Depending on the course of the disease, pneumonia may involve one or more lobes simultaneously (Fig. 1a, c, g). When one or two lobes are involved, the effect on lung function is not serious, and the symptoms of shortness of breath and dyspnea are not severe. As the disease progresses, the consolidation area of the lung begins to absorb, reducing its density and gradually becoming a ground glass opacity, like “melted sugar” (Fig. 1f). At this point, if the patient receives effective treatment or if immunity successfully fights against the virus, the inflammation will be further absorbed and the extent will be minimized. The disease will improve, perhaps leaving the lung fiber cord focus (Fig. 1g). This very much resembles a bout of flu. If the treatment is not received promptly or if immunity fails to fight off the virus, in time, it becomes life-threatening. Lung can progress to a \"white lung\" appearance (Fig. 1h), however, this is only seen in a very small number of patients with diffuse alveolar damage involving multiple lobes. At this stage, the ventilation function will be seriously impaired, requiring continuous oxygen inhalation, and even extracorporeal membrane pulmonary oxygenation (ECMO).\nFigure 1. CT images of 2019-nCoV related pneumonia.a–c. ground glass opacities; (d) pulmonary consolidation and nodules; (e) local consolidation in the center with peripheral ground glass opacity; (f) as the disease progresses, the consolidation area of the lung begins to absorb, reducing its density and gradually becoming ground glass opacity, like a “melted sugar”; (g) the inflammation has absorbed, leaving the lung fiber cord focus; (h) the pneumonia deteriorated and the lungs progressed to the “white lung” stage"}

LitCovid-PD-GO-BP

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T2","span":{"begin":1164,"end":1176},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T3","span":{"begin":2204,"end":2216},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"Chest CT examination is very important in the initial diagnosis of the new type of pneumonia, and CT changes are variable. By collecting chest CT of patients with 2019-nCov related pneumonia in our hospital, we summarized the common imaging changes of the patients. CT is often found to be positive when patients with 2019-nCoV develop persistent fever, cough, and unexplained weakness. Early CT lung manifestations are diverse: they may be lung ground glass shadow (Fig. 1a–c), pulmonary consolidation and nodules (Fig. 1d), and local consolidation in the center with ground glass density around (Fig. 1e). Depending on the course of the disease, pneumonia may involve one or more lobes simultaneously (Fig. 1a, c, g). When one or two lobes are involved, the effect on lung function is not serious, and the symptoms of shortness of breath and dyspnea are not severe. As the disease progresses, the consolidation area of the lung begins to absorb, reducing its density and gradually becoming a ground glass opacity, like “melted sugar” (Fig. 1f). At this point, if the patient receives effective treatment or if immunity successfully fights against the virus, the inflammation will be further absorbed and the extent will be minimized. The disease will improve, perhaps leaving the lung fiber cord focus (Fig. 1g). This very much resembles a bout of flu. If the treatment is not received promptly or if immunity fails to fight off the virus, in time, it becomes life-threatening. Lung can progress to a \"white lung\" appearance (Fig. 1h), however, this is only seen in a very small number of patients with diffuse alveolar damage involving multiple lobes. At this stage, the ventilation function will be seriously impaired, requiring continuous oxygen inhalation, and even extracorporeal membrane pulmonary oxygenation (ECMO).\nFigure 1. CT images of 2019-nCoV related pneumonia.a–c. ground glass opacities; (d) pulmonary consolidation and nodules; (e) local consolidation in the center with peripheral ground glass opacity; (f) as the disease progresses, the consolidation area of the lung begins to absorb, reducing its density and gradually becoming ground glass opacity, like a “melted sugar”; (g) the inflammation has absorbed, leaving the lung fiber cord focus; (h) the pneumonia deteriorated and the lungs progressed to the “white lung” stage"}

LitCovid-sentences

{"project":"LitCovid-sentences","denotations":[{"id":"T17","span":{"begin":0,"end":122},"obj":"Sentence"},{"id":"T18","span":{"begin":123,"end":265},"obj":"Sentence"},{"id":"T19","span":{"begin":266,"end":386},"obj":"Sentence"},{"id":"T20","span":{"begin":387,"end":607},"obj":"Sentence"},{"id":"T21","span":{"begin":608,"end":719},"obj":"Sentence"},{"id":"T22","span":{"begin":720,"end":867},"obj":"Sentence"},{"id":"T23","span":{"begin":868,"end":1046},"obj":"Sentence"},{"id":"T24","span":{"begin":1047,"end":1235},"obj":"Sentence"},{"id":"T25","span":{"begin":1236,"end":1314},"obj":"Sentence"},{"id":"T26","span":{"begin":1315,"end":1354},"obj":"Sentence"},{"id":"T27","span":{"begin":1355,"end":1479},"obj":"Sentence"},{"id":"T28","span":{"begin":1480,"end":1654},"obj":"Sentence"},{"id":"T29","span":{"begin":1655,"end":1825},"obj":"Sentence"},{"id":"T30","span":{"begin":1826,"end":1835},"obj":"Sentence"},{"id":"T31","span":{"begin":1836,"end":2347},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Chest CT examination is very important in the initial diagnosis of the new type of pneumonia, and CT changes are variable. By collecting chest CT of patients with 2019-nCov related pneumonia in our hospital, we summarized the common imaging changes of the patients. CT is often found to be positive when patients with 2019-nCoV develop persistent fever, cough, and unexplained weakness. Early CT lung manifestations are diverse: they may be lung ground glass shadow (Fig. 1a–c), pulmonary consolidation and nodules (Fig. 1d), and local consolidation in the center with ground glass density around (Fig. 1e). Depending on the course of the disease, pneumonia may involve one or more lobes simultaneously (Fig. 1a, c, g). When one or two lobes are involved, the effect on lung function is not serious, and the symptoms of shortness of breath and dyspnea are not severe. As the disease progresses, the consolidation area of the lung begins to absorb, reducing its density and gradually becoming a ground glass opacity, like “melted sugar” (Fig. 1f). At this point, if the patient receives effective treatment or if immunity successfully fights against the virus, the inflammation will be further absorbed and the extent will be minimized. The disease will improve, perhaps leaving the lung fiber cord focus (Fig. 1g). This very much resembles a bout of flu. If the treatment is not received promptly or if immunity fails to fight off the virus, in time, it becomes life-threatening. Lung can progress to a \"white lung\" appearance (Fig. 1h), however, this is only seen in a very small number of patients with diffuse alveolar damage involving multiple lobes. At this stage, the ventilation function will be seriously impaired, requiring continuous oxygen inhalation, and even extracorporeal membrane pulmonary oxygenation (ECMO).\nFigure 1. CT images of 2019-nCoV related pneumonia.a–c. ground glass opacities; (d) pulmonary consolidation and nodules; (e) local consolidation in the center with peripheral ground glass opacity; (f) as the disease progresses, the consolidation area of the lung begins to absorb, reducing its density and gradually becoming ground glass opacity, like a “melted sugar”; (g) the inflammation has absorbed, leaving the lung fiber cord focus; (h) the pneumonia deteriorated and the lungs progressed to the “white lung” stage"}

LitCovid-PD-HP

{"project":"LitCovid-PD-HP","denotations":[{"id":"T6","span":{"begin":83,"end":92},"obj":"Phenotype"},{"id":"T7","span":{"begin":181,"end":190},"obj":"Phenotype"},{"id":"T8","span":{"begin":347,"end":352},"obj":"Phenotype"},{"id":"T9","span":{"begin":354,"end":359},"obj":"Phenotype"},{"id":"T10","span":{"begin":648,"end":657},"obj":"Phenotype"},{"id":"T11","span":{"begin":820,"end":839},"obj":"Phenotype"},{"id":"T12","span":{"begin":844,"end":851},"obj":"Phenotype"},{"id":"T13","span":{"begin":1605,"end":1628},"obj":"Phenotype"},{"id":"T14","span":{"begin":2274,"end":2283},"obj":"Phenotype"}],"attributes":[{"id":"A6","pred":"hp_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A7","pred":"hp_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A8","pred":"hp_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A9","pred":"hp_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/HP_0012735"},{"id":"A10","pred":"hp_id","subj":"T10","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A11","pred":"hp_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"id":"A12","pred":"hp_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/HP_0002094"},{"id":"A13","pred":"hp_id","subj":"T13","obj":"http://purl.obolibrary.org/obo/HP_0033006"},{"id":"A14","pred":"hp_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"Chest CT examination is very important in the initial diagnosis of the new type of pneumonia, and CT changes are variable. By collecting chest CT of patients with 2019-nCov related pneumonia in our hospital, we summarized the common imaging changes of the patients. CT is often found to be positive when patients with 2019-nCoV develop persistent fever, cough, and unexplained weakness. Early CT lung manifestations are diverse: they may be lung ground glass shadow (Fig. 1a–c), pulmonary consolidation and nodules (Fig. 1d), and local consolidation in the center with ground glass density around (Fig. 1e). Depending on the course of the disease, pneumonia may involve one or more lobes simultaneously (Fig. 1a, c, g). When one or two lobes are involved, the effect on lung function is not serious, and the symptoms of shortness of breath and dyspnea are not severe. As the disease progresses, the consolidation area of the lung begins to absorb, reducing its density and gradually becoming a ground glass opacity, like “melted sugar” (Fig. 1f). At this point, if the patient receives effective treatment or if immunity successfully fights against the virus, the inflammation will be further absorbed and the extent will be minimized. The disease will improve, perhaps leaving the lung fiber cord focus (Fig. 1g). This very much resembles a bout of flu. If the treatment is not received promptly or if immunity fails to fight off the virus, in time, it becomes life-threatening. Lung can progress to a \"white lung\" appearance (Fig. 1h), however, this is only seen in a very small number of patients with diffuse alveolar damage involving multiple lobes. At this stage, the ventilation function will be seriously impaired, requiring continuous oxygen inhalation, and even extracorporeal membrane pulmonary oxygenation (ECMO).\nFigure 1. CT images of 2019-nCoV related pneumonia.a–c. ground glass opacities; (d) pulmonary consolidation and nodules; (e) local consolidation in the center with peripheral ground glass opacity; (f) as the disease progresses, the consolidation area of the lung begins to absorb, reducing its density and gradually becoming ground glass opacity, like a “melted sugar”; (g) the inflammation has absorbed, leaving the lung fiber cord focus; (h) the pneumonia deteriorated and the lungs progressed to the “white lung” stage"}

PMC:7075276 / 2181-4528 JSONTXT

Annnotations TAB JSON ListView MergeView

PMC:7075276 / 2181-4528 JSON TXT