PMC:7074424 / 26880-27257
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 608 | 159-167 | Gene | denotes | helicase | Gene:164045 |
| 609 | 276-284 | Gene | denotes | helicase | Gene:164045 |
| 612 | 20-23 | Chemical | denotes | ATP | MESH:D000255 |
| 613 | 25-29 | Chemical | denotes | dATP | MESH:C026600 |
| 614 | 35-39 | Chemical | denotes | dCTP | MESH:C024107 |
| 615 | 78-82 | Chemical | denotes | NTPs | |
| 616 | 88-96 | Disease | denotes | Toxicity | MESH:D064420 |
| 617 | 220-228 | Disease | denotes | toxicity | MESH:D064420 |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32201449-20071563-47217144 | 84-86 | 20071563 | denotes | 88 |
| 32201449-16611118-47217145 | 230-232 | 16611118 | denotes | 87 |
| 32201449-27064001-47217146 | 374-376 | 27064001 | denotes | 89 |
| T33859 | 84-86 | 20071563 | denotes | 88 |
| T41240 | 230-232 | 16611118 | denotes | 87 |
| T97464 | 374-376 | 27064001 | denotes | 89 |
LitCovid-PMC-OGER-BB
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T835 | 63-73 | MOP:0000619 | denotes | hydrolyzed |
| T834 | 145-155 | CHEBI:35222;CHEBI:35222 | denotes | inhibitors |
| T833 | 191-201 | CHEBI:35222;CHEBI:35222 | denotes | inhibitors |
| T832 | 323-332 | CHEBI:23888;CHEBI:23888 | denotes | druggable |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T270 | 321-322 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | chebi_id |
|---|---|---|---|---|---|
| T341 | 20-23 | Chemical | denotes | ATP | http://purl.obolibrary.org/obo/CHEBI_15422|http://purl.obolibrary.org/obo/CHEBI_30616 |
| T343 | 25-29 | Chemical | denotes | dATP | http://purl.obolibrary.org/obo/CHEBI_16284|http://purl.obolibrary.org/obo/CHEBI_61404 |
| T345 | 35-39 | Chemical | denotes | dCTP | http://purl.obolibrary.org/obo/CHEBI_16311|http://purl.obolibrary.org/obo/CHEBI_61481 |
| T347 | 145-155 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
| T348 | 191-201 | Chemical | denotes | inhibitors | http://purl.obolibrary.org/obo/CHEBI_35222 |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T159 | 0-377 | Sentence | denotes | This enzyme prefers ATP, dATP, and dCTP as substrates; it also hydrolyzed all NTPs.[88] Toxicity issues are main obstacles in the development of inhibitors of helicase, and nonspecificity of inhibitors may cause serious toxicity.[87] However, despite theoretical limitations, helicase is being increasingly recognized as a druggable target for different disease conditions.[89] |