PMC:7074424 / 21846-22131 JSONTXT

{"project":"LitCovid-PubTator","denotations":[{"id":"474","span":{"begin":63,"end":83},"obj":"Gene"},{"id":"492","span":{"begin":47,"end":51},"obj":"Chemical"},{"id":"493","span":{"begin":124,"end":126},"obj":"Chemical"},{"id":"494","span":{"begin":128,"end":190},"obj":"Chemical"}],"attributes":[{"id":"A474","pred":"tao:has_database_id","subj":"474","obj":"Gene:918763"},{"id":"A492","pred":"tao:has_database_id","subj":"492","obj":"MESH:C434926"},{"id":"A493","pred":"tao:has_database_id","subj":"493","obj":"MESH:C012616"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"4KXJ.[26] On the basis of interactions between PJ34 and NTD of nucleocapsid protein, another inhibitor was designed that is H3 (6-chloro-7-(2-morpholin-4-yl-ethylamino) quinoxaline-5,8-dione), which also inhibits RNA binding.[2669] This highlights the importance of NTD in RNA binding."}

{"project":"2_test","denotations":[{"id":"32201449-24564608-47217107","span":{"begin":6,"end":8},"obj":"24564608"},{"id":"32201449-24564608-47217108","span":{"begin":226,"end":228},"obj":"24564608"},{"id":"32201449-26542199-47217109","span":{"begin":226,"end":230},"obj":"26542199"},{"id":"T31768","span":{"begin":6,"end":8},"obj":"24564608"},{"id":"T96844","span":{"begin":226,"end":228},"obj":"24564608"},{"id":"T90388","span":{"begin":226,"end":230},"obj":"26542199"}],"text":"4KXJ.[26] On the basis of interactions between PJ34 and NTD of nucleocapsid protein, another inhibitor was designed that is H3 (6-chloro-7-(2-morpholin-4-yl-ethylamino) quinoxaline-5,8-dione), which also inhibits RNA binding.[2669] This highlights the importance of NTD in RNA binding."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T648","span":{"begin":63,"end":83},"obj":"PG_4"},{"id":"T647","span":{"begin":93,"end":102},"obj":"CHEBI:35222;CHEBI:35222"},{"id":"T646","span":{"begin":142,"end":151},"obj":"CHEBI:34856;CHEBI:34856"},{"id":"T645","span":{"begin":151,"end":157},"obj":"CHEBI:53233;CHEBI:53233"},{"id":"T644","span":{"begin":157,"end":167},"obj":"CHEBI:27750;CHEBI:27750"},{"id":"T643","span":{"begin":167,"end":168},"obj":"CHEBI:53233;CHEBI:53233"},{"id":"T642","span":{"begin":169,"end":180},"obj":"CHEBI:36616;CHEBI:36616"},{"id":"T641","span":{"begin":180,"end":190},"obj":"CHEBI:53233;CHEBI:53233"}],"text":"4KXJ.[26] On the basis of interactions between PJ34 and NTD of nucleocapsid protein, another inhibitor was designed that is H3 (6-chloro-7-(2-morpholin-4-yl-ethylamino) quinoxaline-5,8-dione), which also inhibits RNA binding.[2669] This highlights the importance of NTD in RNA binding."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T237","span":{"begin":76,"end":83},"obj":"Body_part"},{"id":"T238","span":{"begin":124,"end":126},"obj":"Body_part"},{"id":"T239","span":{"begin":213,"end":216},"obj":"Body_part"},{"id":"T240","span":{"begin":273,"end":276},"obj":"Body_part"}],"attributes":[{"id":"A237","pred":"fma_id","subj":"T237","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A238","pred":"fma_id","subj":"T238","obj":"http://purl.org/sig/ont/fma/fma84131"},{"id":"A239","pred":"fma_id","subj":"T239","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A240","pred":"fma_id","subj":"T240","obj":"http://purl.org/sig/ont/fma/fma67095"}],"text":"4KXJ.[26] On the basis of interactions between PJ34 and NTD of nucleocapsid protein, another inhibitor was designed that is H3 (6-chloro-7-(2-morpholin-4-yl-ethylamino) quinoxaline-5,8-dione), which also inhibits RNA binding.[2669] This highlights the importance of NTD in RNA binding."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T118","span":{"begin":56,"end":59},"obj":"Disease"},{"id":"T120","span":{"begin":266,"end":269},"obj":"Disease"}],"attributes":[{"id":"A118","pred":"mondo_id","subj":"T118","obj":"http://purl.obolibrary.org/obo/MONDO_0008449"},{"id":"A119","pred":"mondo_id","subj":"T118","obj":"http://purl.obolibrary.org/obo/MONDO_0018075"},{"id":"A120","pred":"mondo_id","subj":"T120","obj":"http://purl.obolibrary.org/obo/MONDO_0008449"},{"id":"A121","pred":"mondo_id","subj":"T120","obj":"http://purl.obolibrary.org/obo/MONDO_0018075"}],"text":"4KXJ.[26] On the basis of interactions between PJ34 and NTD of nucleocapsid protein, another inhibitor was designed that is H3 (6-chloro-7-(2-morpholin-4-yl-ethylamino) quinoxaline-5,8-dione), which also inhibits RNA binding.[2669] This highlights the importance of NTD in RNA binding."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T255","span":{"begin":76,"end":83},"obj":"Chemical"},{"id":"T256","span":{"begin":93,"end":102},"obj":"Chemical"},{"id":"T257","span":{"begin":130,"end":136},"obj":"Chemical"},{"id":"T258","span":{"begin":169,"end":180},"obj":"Chemical"}],"attributes":[{"id":"A255","pred":"chebi_id","subj":"T255","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A256","pred":"chebi_id","subj":"T256","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A257","pred":"chebi_id","subj":"T257","obj":"http://purl.obolibrary.org/obo/CHEBI_47853"},{"id":"A258","pred":"chebi_id","subj":"T258","obj":"http://purl.obolibrary.org/obo/CHEBI_36616"}],"text":"4KXJ.[26] On the basis of interactions between PJ34 and NTD of nucleocapsid protein, another inhibitor was designed that is H3 (6-chloro-7-(2-morpholin-4-yl-ethylamino) quinoxaline-5,8-dione), which also inhibits RNA binding.[2669] This highlights the importance of NTD in RNA binding."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T59","span":{"begin":204,"end":224},"obj":"http://purl.obolibrary.org/obo/GO_1905215"}],"text":"4KXJ.[26] On the basis of interactions between PJ34 and NTD of nucleocapsid protein, another inhibitor was designed that is H3 (6-chloro-7-(2-morpholin-4-yl-ethylamino) quinoxaline-5,8-dione), which also inhibits RNA binding.[2669] This highlights the importance of NTD in RNA binding."}

{"project":"LitCovid-sentences","denotations":[{"id":"T128","span":{"begin":0,"end":285},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"4KXJ.[26] On the basis of interactions between PJ34 and NTD of nucleocapsid protein, another inhibitor was designed that is H3 (6-chloro-7-(2-morpholin-4-yl-ethylamino) quinoxaline-5,8-dione), which also inhibits RNA binding.[2669] This highlights the importance of NTD in RNA binding."}