PMC:7074424 / 15638-16072 JSONTXT

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{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T143","span":{"begin":96,"end":100},"obj":"Body_part"},{"id":"T144","span":{"begin":114,"end":119},"obj":"Body_part"},{"id":"T145","span":{"begin":240,"end":245},"obj":"Body_part"},{"id":"T146","span":{"begin":290,"end":297},"obj":"Body_part"},{"id":"T147","span":{"begin":397,"end":402},"obj":"Body_part"}],"attributes":[{"id":"A143","pred":"fma_id","subj":"T143","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A144","pred":"fma_id","subj":"T144","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A145","pred":"fma_id","subj":"T145","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A146","pred":"fma_id","subj":"T146","obj":"http://purl.org/sig/ont/fma/fma82743"},{"id":"A147","pred":"fma_id","subj":"T147","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":" al. identified 18 small molecules that targeted the S-ACE-2-mediated entry of virus into human cell.[53] In 293T cells expressing ACE-2, one of these agents (VE607) showed a significant inhibition of SARS-pseudovirus entry.[53] In Vero E6 cells, two other molecules tetra-O-galloyl beta-D-glucose and luteolin also inhibited SARS-pseudovirus and SARS-CoV infection.[53] In virus-infected Vero E6 cells, a siRNA against the S sequence"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T79","span":{"begin":201,"end":205},"obj":"Disease"},{"id":"T80","span":{"begin":326,"end":330},"obj":"Disease"},{"id":"T81","span":{"begin":347,"end":365},"obj":"Disease"},{"id":"T82","span":{"begin":347,"end":351},"obj":"Disease"},{"id":"T83","span":{"begin":356,"end":365},"obj":"Disease"}],"attributes":[{"id":"A79","pred":"mondo_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A80","pred":"mondo_id","subj":"T80","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A81","pred":"mondo_id","subj":"T81","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A82","pred":"mondo_id","subj":"T82","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A83","pred":"mondo_id","subj":"T83","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"}],"text":" al. identified 18 small molecules that targeted the S-ACE-2-mediated entry of virus into human cell.[53] In 293T cells expressing ACE-2, one of these agents (VE607) showed a significant inhibition of SARS-pseudovirus entry.[53] In Vero E6 cells, two other molecules tetra-O-galloyl beta-D-glucose and luteolin also inhibited SARS-pseudovirus and SARS-CoV infection.[53] In virus-infected Vero E6 cells, a siRNA against the S sequence"}

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