PMC:7068984 / 16036-17154 JSONTXT

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In addition, a part of patients manifested gastrointestinal symptoms, with diarrhea (3.8%) and vomiting (5.0%). The clinical manifestations were in consistence with the previous data of 41, 99, and 138 patients analysis in Hubei province [46, 48, 50]. Fever and cough were the dominant symptoms whereas upper respiratory symptoms and gastrointestinal symptoms were rare, suggesting the differences in viral tropism as compared with SARS-CoV [51], MERS-CoV [52], and influenza [53]. The elderly and those with underlying disorders (i.e., hypertension, chronic obstructive pulmonary disease, diabetes, cardiovascular disease), developed rapidly into acute respiratory distress syndrome, septic shock, metabolic acidosis hard to correct and coagulation dysfunction, even leading to the death [48] (lower panel, Fig. 1)."}

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T90","span":{"begin":198,"end":204},"obj":"Body_part"},{"id":"T91","span":{"begin":259,"end":265},"obj":"Body_part"}],"attributes":[{"id":"A90","pred":"fma_id","subj":"T90","obj":"http://purl.org/sig/ont/fma/fma312401"},{"id":"A91","pred":"fma_id","subj":"T91","obj":"http://purl.org/sig/ont/fma/fma228738"}],"text":"A recent study led by Prof. Nan-Shan Zhong’s team, by sampling 1099 laboratory-confirmed cases, found that the common clinical manifestations included fever (88.7%), cough (67.8%), fatigue (38.1%), sputum production (33.4%), shortness of breath (18.6%), sore throat (13.9%), and headache (13.6%) [16]. In addition, a part of patients manifested gastrointestinal symptoms, with diarrhea (3.8%) and vomiting (5.0%). The clinical manifestations were in consistence with the previous data of 41, 99, and 138 patients analysis in Hubei province [46, 48, 50]. Fever and cough were the dominant symptoms whereas upper respiratory symptoms and gastrointestinal symptoms were rare, suggesting the differences in viral tropism as compared with SARS-CoV [51], MERS-CoV [52], and influenza [53]. The elderly and those with underlying disorders (i.e., hypertension, chronic obstructive pulmonary disease, diabetes, cardiovascular disease), developed rapidly into acute respiratory distress syndrome, septic shock, metabolic acidosis hard to correct and coagulation dysfunction, even leading to the death [48] (lower panel, Fig. 1)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T15","span":{"begin":198,"end":204},"obj":"Body_part"},{"id":"T16","span":{"begin":259,"end":265},"obj":"Body_part"}],"attributes":[{"id":"A15","pred":"uberon_id","subj":"T15","obj":"http://purl.obolibrary.org/obo/UBERON_0007311"},{"id":"A16","pred":"uberon_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/UBERON_0000341"}],"text":"A recent study led by Prof. Nan-Shan Zhong’s team, by sampling 1099 laboratory-confirmed cases, found that the common clinical manifestations included fever (88.7%), cough (67.8%), fatigue (38.1%), sputum production (33.4%), shortness of breath (18.6%), sore throat (13.9%), and headache (13.6%) [16]. In addition, a part of patients manifested gastrointestinal symptoms, with diarrhea (3.8%) and vomiting (5.0%). The clinical manifestations were in consistence with the previous data of 41, 99, and 138 patients analysis in Hubei province [46, 48, 50]. Fever and cough were the dominant symptoms whereas upper respiratory symptoms and gastrointestinal symptoms were rare, suggesting the differences in viral tropism as compared with SARS-CoV [51], MERS-CoV [52], and influenza [53]. The elderly and those with underlying disorders (i.e., hypertension, chronic obstructive pulmonary disease, diabetes, cardiovascular disease), developed rapidly into acute respiratory distress syndrome, septic shock, metabolic acidosis hard to correct and coagulation dysfunction, even leading to the death [48] (lower panel, Fig. 1)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T122","span":{"begin":254,"end":265},"obj":"Disease"},{"id":"T123","span":{"begin":377,"end":385},"obj":"Disease"},{"id":"T124","span":{"begin":734,"end":742},"obj":"Disease"},{"id":"T125","span":{"begin":768,"end":777},"obj":"Disease"},{"id":"T126","span":{"begin":839,"end":851},"obj":"Disease"},{"id":"T127","span":{"begin":853,"end":890},"obj":"Disease"},{"id":"T128","span":{"begin":873,"end":890},"obj":"Disease"},{"id":"T129","span":{"begin":892,"end":900},"obj":"Disease"},{"id":"T130","span":{"begin":902,"end":924},"obj":"Disease"},{"id":"T131","span":{"begin":950,"end":985},"obj":"Disease"},{"id":"T132","span":{"begin":956,"end":985},"obj":"Disease"},{"id":"T133","span":{"begin":1001,"end":1019},"obj":"Disease"},{"id":"T134","span":{"begin":1011,"end":1019},"obj":"Disease"}],"attributes":[{"id":"A122","pred":"mondo_id","subj":"T122","obj":"http://purl.obolibrary.org/obo/MONDO_0002258"},{"id":"A123","pred":"mondo_id","subj":"T123","obj":"http://purl.obolibrary.org/obo/MONDO_0001673"},{"id":"A124","pred":"mondo_id","subj":"T124","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A125","pred":"mondo_id","subj":"T125","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A126","pred":"mondo_id","subj":"T126","obj":"http://purl.obolibrary.org/obo/MONDO_0005044"},{"id":"A127","pred":"mondo_id","subj":"T127","obj":"http://purl.obolibrary.org/obo/MONDO_0005002"},{"id":"A128","pred":"mondo_id","subj":"T128","obj":"http://purl.obolibrary.org/obo/MONDO_0005275"},{"id":"A129","pred":"mondo_id","subj":"T129","obj":"http://purl.obolibrary.org/obo/MONDO_0005015"},{"id":"A130","pred":"mondo_id","subj":"T130","obj":"http://purl.obolibrary.org/obo/MONDO_0004995"},{"id":"A131","pred":"mondo_id","subj":"T131","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A132","pred":"mondo_id","subj":"T132","obj":"http://purl.obolibrary.org/obo/MONDO_0009971"},{"id":"A133","pred":"mondo_id","subj":"T133","obj":"http://purl.obolibrary.org/obo/MONDO_0000440"},{"id":"A134","pred":"mondo_id","subj":"T134","obj":"http://purl.obolibrary.org/obo/MONDO_0006022"}],"text":"A recent study led by Prof. Nan-Shan Zhong’s team, by sampling 1099 laboratory-confirmed cases, found that the common clinical manifestations included fever (88.7%), cough (67.8%), fatigue (38.1%), sputum production (33.4%), shortness of breath (18.6%), sore throat (13.9%), and headache (13.6%) [16]. In addition, a part of patients manifested gastrointestinal symptoms, with diarrhea (3.8%) and vomiting (5.0%). The clinical manifestations were in consistence with the previous data of 41, 99, and 138 patients analysis in Hubei province [46, 48, 50]. Fever and cough were the dominant symptoms whereas upper respiratory symptoms and gastrointestinal symptoms were rare, suggesting the differences in viral tropism as compared with SARS-CoV [51], MERS-CoV [52], and influenza [53]. The elderly and those with underlying disorders (i.e., hypertension, chronic obstructive pulmonary disease, diabetes, cardiovascular disease), developed rapidly into acute respiratory distress syndrome, septic shock, metabolic acidosis hard to correct and coagulation dysfunction, even leading to the death [48] (lower panel, Fig. 1)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T146","span":{"begin":0,"end":1},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T147","span":{"begin":315,"end":316},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T148","span":{"begin":488,"end":490},"obj":"http://purl.obolibrary.org/obo/CLO_0053794"},{"id":"T149","span":{"begin":545,"end":547},"obj":"http://purl.obolibrary.org/obo/CLO_0001382"},{"id":"T150","span":{"begin":759,"end":761},"obj":"http://purl.obolibrary.org/obo/CLO_0001407"},{"id":"T151","span":{"begin":1092,"end":1094},"obj":"http://purl.obolibrary.org/obo/CLO_0001382"}],"text":"A recent study led by Prof. Nan-Shan Zhong’s team, by sampling 1099 laboratory-confirmed cases, found that the common clinical manifestations included fever (88.7%), cough (67.8%), fatigue (38.1%), sputum production (33.4%), shortness of breath (18.6%), sore throat (13.9%), and headache (13.6%) [16]. In addition, a part of patients manifested gastrointestinal symptoms, with diarrhea (3.8%) and vomiting (5.0%). The clinical manifestations were in consistence with the previous data of 41, 99, and 138 patients analysis in Hubei province [46, 48, 50]. Fever and cough were the dominant symptoms whereas upper respiratory symptoms and gastrointestinal symptoms were rare, suggesting the differences in viral tropism as compared with SARS-CoV [51], MERS-CoV [52], and influenza [53]. The elderly and those with underlying disorders (i.e., hypertension, chronic obstructive pulmonary disease, diabetes, cardiovascular disease), developed rapidly into acute respiratory distress syndrome, septic shock, metabolic acidosis hard to correct and coagulation dysfunction, even leading to the death [48] (lower panel, Fig. 1)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T21","span":{"begin":709,"end":716},"obj":"http://purl.obolibrary.org/obo/GO_0009606"},{"id":"T22","span":{"begin":1040,"end":1051},"obj":"http://purl.obolibrary.org/obo/GO_0050817"}],"text":"A recent study led by Prof. Nan-Shan Zhong’s team, by sampling 1099 laboratory-confirmed cases, found that the common clinical manifestations included fever (88.7%), cough (67.8%), fatigue (38.1%), sputum production (33.4%), shortness of breath (18.6%), sore throat (13.9%), and headache (13.6%) [16]. In addition, a part of patients manifested gastrointestinal symptoms, with diarrhea (3.8%) and vomiting (5.0%). The clinical manifestations were in consistence with the previous data of 41, 99, and 138 patients analysis in Hubei province [46, 48, 50]. Fever and cough were the dominant symptoms whereas upper respiratory symptoms and gastrointestinal symptoms were rare, suggesting the differences in viral tropism as compared with SARS-CoV [51], MERS-CoV [52], and influenza [53]. The elderly and those with underlying disorders (i.e., hypertension, chronic obstructive pulmonary disease, diabetes, cardiovascular disease), developed rapidly into acute respiratory distress syndrome, septic shock, metabolic acidosis hard to correct and coagulation dysfunction, even leading to the death [48] (lower panel, Fig. 1)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T111","span":{"begin":0,"end":301},"obj":"Sentence"},{"id":"T112","span":{"begin":302,"end":413},"obj":"Sentence"},{"id":"T113","span":{"begin":414,"end":553},"obj":"Sentence"},{"id":"T114","span":{"begin":554,"end":783},"obj":"Sentence"},{"id":"T115","span":{"begin":784,"end":1118},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"A recent study led by Prof. Nan-Shan Zhong’s team, by sampling 1099 laboratory-confirmed cases, found that the common clinical manifestations included fever (88.7%), cough (67.8%), fatigue (38.1%), sputum production (33.4%), shortness of breath (18.6%), sore throat (13.9%), and headache (13.6%) [16]. In addition, a part of patients manifested gastrointestinal symptoms, with diarrhea (3.8%) and vomiting (5.0%). The clinical manifestations were in consistence with the previous data of 41, 99, and 138 patients analysis in Hubei province [46, 48, 50]. Fever and cough were the dominant symptoms whereas upper respiratory symptoms and gastrointestinal symptoms were rare, suggesting the differences in viral tropism as compared with SARS-CoV [51], MERS-CoV [52], and influenza [53]. The elderly and those with underlying disorders (i.e., hypertension, chronic obstructive pulmonary disease, diabetes, cardiovascular disease), developed rapidly into acute respiratory distress syndrome, septic shock, metabolic acidosis hard to correct and coagulation dysfunction, even leading to the death [48] (lower panel, Fig. 1)."}

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{"project":"2_test","denotations":[{"id":"32169119-31986264-70132220","span":{"begin":545,"end":547},"obj":"31986264"},{"id":"32169119-32007143-70132221","span":{"begin":549,"end":551},"obj":"32007143"},{"id":"32169119-12682352-70132222","span":{"begin":744,"end":746},"obj":"12682352"},{"id":"32169119-23891402-70132223","span":{"begin":759,"end":761},"obj":"23891402"},{"id":"32169119-27716101-70132224","span":{"begin":779,"end":781},"obj":"27716101"},{"id":"32169119-31986264-70132225","span":{"begin":1092,"end":1094},"obj":"31986264"}],"text":"A recent study led by Prof. Nan-Shan Zhong’s team, by sampling 1099 laboratory-confirmed cases, found that the common clinical manifestations included fever (88.7%), cough (67.8%), fatigue (38.1%), sputum production (33.4%), shortness of breath (18.6%), sore throat (13.9%), and headache (13.6%) [16]. In addition, a part of patients manifested gastrointestinal symptoms, with diarrhea (3.8%) and vomiting (5.0%). The clinical manifestations were in consistence with the previous data of 41, 99, and 138 patients analysis in Hubei province [46, 48, 50]. Fever and cough were the dominant symptoms whereas upper respiratory symptoms and gastrointestinal symptoms were rare, suggesting the differences in viral tropism as compared with SARS-CoV [51], MERS-CoV [52], and influenza [53]. The elderly and those with underlying disorders (i.e., hypertension, chronic obstructive pulmonary disease, diabetes, cardiovascular disease), developed rapidly into acute respiratory distress syndrome, septic shock, metabolic acidosis hard to correct and coagulation dysfunction, even leading to the death [48] (lower panel, Fig. 1)."}