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PMC:7067204 / 16949-18513 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
957 1425-1427 Gene denotes of Gene:6688
958 1393-1395 Gene denotes of Gene:6688
959 1459-1468 Species denotes 2019-nCoV Tax:2697049
960 1484-1492 Species denotes SARS-CoV Tax:694009
961 1497-1513 Species denotes SARS-related CoV Tax:694009
991 511-513 Gene denotes as Gene:112935892
992 1154-1156 Gene denotes of Gene:6688
993 1229-1232 Gene denotes bat Gene:570
994 753-756 Gene denotes bat Gene:570
995 502-504 Gene denotes as Gene:112935892
996 1283-1286 Gene denotes The Gene:25085
997 1157-1160 Gene denotes the Gene:25085
998 821-824 Gene denotes the Gene:25085
999 635-637 Gene denotes to Gene:6999
1000 233-235 Gene denotes to Gene:6999
1001 215-217 Gene denotes to Gene:6999
1002 68-70 Gene denotes to Gene:6999
1003 92-96 Gene denotes SARS Gene:6301
1004 1298-1300 Gene denotes of Gene:6688
1005 864-866 Gene denotes of Gene:6688
1006 657-659 Gene denotes of Gene:6688
1007 242-244 Gene denotes of Gene:6688
1008 80-88 Species denotes SARS-CoV Tax:694009
1009 99-102 Species denotes CoV Tax:11118
1010 165-173 Species denotes SARS-CoV Tax:694009
1011 757-773 Species denotes SARS-related-CoV Tax:694009
1012 867-875 Species denotes SARS-CoV Tax:694009
1013 937-953 Species denotes SARS-related-CoV Tax:694009
1014 1233-1249 Species denotes SARS-related-CoV Tax:694009
1015 1321-1330 Species denotes 2019-nCoV Tax:2697049
1016 493-501 Disease denotes necrosis MESH:D009336
1017 564-572 Disease denotes necrosis MESH:D009336
1018 415-417 CellLine denotes E6 CVCL:4582
1019 426-430 CellLine denotes 293T CVCL:0063

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T81 29-36 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T82 103-110 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T83 272-276 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T84 431-436 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T85 827-843 Body_part denotes terminal nucleus http://purl.org/sig/ont/fma/fma54529
T86 1068-1076 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T87 1161-1170 Body_part denotes protein's http://purl.org/sig/ont/fma/fma67257
T88 1310-1317 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T89 1434-1441 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T90 1541-1548 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257

LitCovid_AGAC

Id Subject Object Predicate Lexical cue
p12744s11 205-214 CPA denotes replicate

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T75 80-88 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T76 92-96 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T77 165-173 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T78 757-761 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T79 867-875 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T80 937-941 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T81 1233-1237 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T82 1484-1492 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T83 1497-1501 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T194 6-7 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T195 255-260 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T196 272-282 http://purl.obolibrary.org/obo/CL_0000000 denotes cell types
T197 377-378 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T198 410-414 http://purl.obolibrary.org/obo/CLO_0009524 denotes Vero
T199 410-414 http://purl.obolibrary.org/obo/CLO_0050515 denotes Vero
T200 426-430 http://purl.obolibrary.org/obo/CLO_0050894 denotes 293T
T201 426-430 http://purl.obolibrary.org/obo/CLO_0051650 denotes 293T
T202 426-430 http://purl.obolibrary.org/obo/CLO_0052052 denotes 293T
T203 431-436 http://purl.obolibrary.org/obo/GO_0005623 denotes cells
T204 454-455 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T205 683-693 http://purl.obolibrary.org/obo/SO_0000418 denotes signalling
T206 753-756 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T207 857-863 http://purl.obolibrary.org/obo/SO_0000418 denotes signal
T208 877-879 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T209 897-905 http://purl.obolibrary.org/obo/CLO_0001658 denotes activity
T210 1011-1021 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T211 1110-1120 http://purl.obolibrary.org/obo/CLO_0001658 denotes activities
T212 1204-1205 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T213 1229-1232 http://purl.obolibrary.org/obo/NCBITaxon_9397 denotes bat
T214 1403-1404 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T215 1515-1516 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T216 1518-1519 http://purl.obolibrary.org/obo/CLO_0001020 denotes A

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T112 29-36 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T113 103-110 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T114 836-843 Chemical denotes nucleus http://purl.obolibrary.org/obo/CHEBI_33252
T115 886-896 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T116 980-990 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T117 1068-1076 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T118 1099-1109 Chemical denotes antagonist http://purl.obolibrary.org/obo/CHEBI_48706
T119 1310-1317 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T120 1434-1441 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T121 1541-1548 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T10 330-347 http://purl.obolibrary.org/obo/GO_0019079 denotes viral replication
T11 330-347 http://purl.obolibrary.org/obo/GO_0019058 denotes viral replication
T12 493-501 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T13 493-501 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T14 493-501 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T15 493-501 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T16 564-572 http://purl.obolibrary.org/obo/GO_0070265 denotes necrosis
T17 564-572 http://purl.obolibrary.org/obo/GO_0019835 denotes necrosis
T18 564-572 http://purl.obolibrary.org/obo/GO_0008219 denotes necrosis
T19 564-572 http://purl.obolibrary.org/obo/GO_0001906 denotes necrosis
T20 577-586 http://purl.obolibrary.org/obo/GO_0097194 denotes apoptosis
T21 577-586 http://purl.obolibrary.org/obo/GO_0006915 denotes apoptosis
T22 669-678 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis
T23 683-693 http://purl.obolibrary.org/obo/GO_0023052 denotes signalling
T24 836-856 http://purl.obolibrary.org/obo/GO_0051647 denotes nucleus localization
T25 844-856 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T26 1179-1191 http://purl.obolibrary.org/obo/GO_0051179 denotes localization
T27 1269-1281 http://purl.obolibrary.org/obo/GO_0009405 denotes pathogenesis

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T181 0-5 Sentence denotes Orf3b
T182 6-145 Sentence denotes A novel short putative protein with 4 helices and no homology to existing SARS-CoV or SARS-r-CoV protein was found within Orf3b (Figure 4).
T183 146-357 Sentence denotes It is notable that SARS-CoV deletion mutants lacking orf3b replicate to levels similar to those of wild-type virus in several cell types [19], suggesting that orf3b is dispensable for viral replication in vitro.
T184 358-613 Sentence denotes But orf3b may have a role in viral pathogenicity as Vero E6 but not 293T cells transfected with a construct expressing Orf3b underwent necrosis as early as 6 h after transfection and underwent simultaneous necrosis and apoptosis at later time points [20].
T185 614-699 Sentence denotes Orf3b was also shown to inhibit expression of IFN-β at synthesis and signalling [21].
T186 700-881 Sentence denotes Subsequently, orf3b homologues identified from three bat SARS-related-CoV strains were C-terminally truncated and lacked the C-terminal nucleus localization signal of SARS-CoV [22].
T187 882-1022 Sentence denotes IFN antagonist activity analysis demonstrated that one SARS-related-CoV orf3b still possessed IFN antagonist and IRF3-modulating activities.
T188 1023-1282 Sentence denotes These results indicated that different orf3b proteins display different IFN antagonist activities and this function is independent of the protein's nuclear localization, suggesting a potential link between bat SARS-related-CoV orf3b function and pathogenesis.
T189 1283-1373 Sentence denotes The importance of this new protein in 2019-nCoV will require further validation and study.
T190 1374-1383 Sentence denotes Figure 4.
T191 1384-1402 Sentence denotes Analysis of orf3b.
T192 1403-1405 Sentence denotes A.
T193 1406-1514 Sentence denotes Multiple alignment of orf3b protein sequence between 2019-nCoV (HKU-SZ-005b), SARS-CoV and SARS-related CoV.
T194 1515-1517 Sentence denotes B.
T195 1518-1564 Sentence denotes A novel putative short protein found in orf3b.

2_test

Id Subject Object Predicate Lexical cue
31987001-16282490-27754487 284-286 16282490 denotes 19
31987001-16965829-27754488 609-611 16965829 denotes 20
31987001-17108024-27754489 695-697 17108024 denotes 21
31987001-22012463-27754490 877-879 22012463 denotes 22

MyTest

Id Subject Object Predicate Lexical cue
31987001-16282490-27754487 284-286 16282490 denotes 19
31987001-16965829-27754488 609-611 16965829 denotes 20
31987001-17108024-27754489 695-697 17108024 denotes 21
31987001-22012463-27754490 877-879 22012463 denotes 22