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PMC:7060195 / 3871-5297 JSONTXT

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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
99 676-677 Gene denotes E Gene:43740570
100 680-688 Gene denotes membrane Gene:43740571
101 690-691 Gene denotes M Gene:43740571
102 708-709 Gene denotes N Gene:43740575
103 716-721 Gene denotes spike Gene:43740568
104 723-724 Gene denotes S Gene:43740568
105 820-823 Gene denotes CD4 Gene:920
106 825-828 Gene denotes CD8 Gene:925
107 694-706 Gene denotes nucleocapsid Gene:43740575
108 24-34 Species denotes SARS-CoV-2 Tax:2697049
109 273-283 Species denotes SARS-CoV-2 Tax:2697049
110 305-313 Species denotes SARS-CoV Tax:694009
111 318-373 Species denotes Middle East respiratory syndrome coronavirus (MERS-CoV) Tax:1335626
112 617-627 Species denotes SARS-CoV-2 Tax:2697049
113 977-986 Disease denotes hepatitis MESH:D056486
114 77-87 CellLine denotes MN908947.3 CVCL:U508
115 89-99 CellLine denotes MN975262.1 CVCL:U508
116 114-124 CellLine denotes MN997409.1 CVCL:U508
117 126-136 CellLine denotes MN985325.1 CVCL:U508
118 138-148 CellLine denotes MN988669.1 CVCL:U508
119 150-160 CellLine denotes MN988668.1 CVCL:U508
120 162-172 CellLine denotes MN994468.1 CVCL:U508
121 174-184 CellLine denotes MN994467.1 CVCL:U508
122 186-196 CellLine denotes MN988713.1 CVCL:U508
123 202-212 CellLine denotes MN938384.1 CVCL:U508

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T7 35-42 Body_part denotes genomes http://purl.org/sig/ont/fma/fma84116
T8 422-425 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T9 439-445 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T10 464-475 Body_part denotes nucleotides http://purl.org/sig/ont/fma/fma82740
T11 648-656 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T12 739-747 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T13 832-836 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T14 1091-1094 Body_part denotes DNA http://purl.org/sig/ont/fma/fma74412
T15 1099-1103 Body_part denotes mRNA http://purl.org/sig/ont/fma/fma67122

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T8 977-986 Phenotype denotes hepatitis http://purl.obolibrary.org/obo/HP_0012115

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T23 24-32 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T24 273-281 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T25 305-313 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T26 617-625 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T27 977-988 Disease denotes hepatitis B http://purl.obolibrary.org/obo/MONDO_0005344
T28 977-986 Disease denotes hepatitis http://purl.obolibrary.org/obo/MONDO_0002251

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T24 243-248 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T25 426-431 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T26 437-438 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T27 608-609 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T28 628-631 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T29 680-688 http://purl.obolibrary.org/obo/UBERON_0000158 denotes membrane
T30 820-823 http://purl.obolibrary.org/obo/PR_000001004 denotes CD4
T31 825-828 http://purl.obolibrary.org/obo/CLO_0053438 denotes CD8
T32 830-836 http://purl.obolibrary.org/obo/CL_0000084 denotes T-cell
T33 987-988 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T34 1066-1072 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T9 464-475 Chemical denotes nucleotides http://purl.obolibrary.org/obo/CHEBI_36976
T10 648-656 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T11 739-747 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080
T12 761-769 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132
T13 921-930 Chemical denotes adjuvants http://purl.obolibrary.org/obo/CHEBI_60809
T14 997-1004 Chemical denotes antigen http://purl.obolibrary.org/obo/CHEBI_59132
T15 1091-1094 Chemical denotes DNA http://purl.obolibrary.org/obo/CHEBI_16991
T16 1364-1372 Chemical denotes antigens http://purl.obolibrary.org/obo/CHEBI_59132

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T7 546-555 http://purl.obolibrary.org/obo/GO_0009058 denotes synthesis

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T29 0-272 Sentence denotes Accumulated releases of SARS-CoV-2 genomes such as GenBank accession numbers MN908947.3, MN975262.1, NC_045512.2, MN997409.1, MN985325.1, MN988669.1, MN988668.1, MN994468.1, MN994467.1, MN988713.1, and MN938384.1 facilitate the development of virus-based subunit vaccines.
T30 273-607 Sentence denotes SARS-CoV-2, which is similar to SARS-CoV and Middle East respiratory syndrome coronavirus (MERS-CoV), is an enveloped, single- and positive-stranded RNA virus with a genome comprising 29,891 nucleotides, which encode the 12 putative open reading frames responsible for the synthesis of viral structural and nonstructural proteins7,10.
T31 608-728 Sentence denotes A mature SARS-CoV-2 has four structural proteins, namely, envelope (E), membrane (M), nucleocapsid (N), and spike (S)10.
T32 729-850 Sentence denotes All these proteins may serve as antigens to stimulate neutralizing antibodies and increase CD4+/CD8+ T-cell responses8,9.
T33 851-1086 Sentence denotes However, subunit vaccines require multiple booster shots and suitable adjuvants to work, and certain subunit vaccines such as hepatitis B surface antigen, PreS1, and PreS2 may fail to yield protective response when tested clinically11.
T34 1087-1205 Sentence denotes The DNA and mRNA vaccines that are easier to design and proceed into clinical trials very quickly remain experimental.
T35 1206-1303 Sentence denotes The viral vector-based vaccines could also be quickly constructed and used without an adjuvant12.
T36 1304-1426 Sentence denotes However, development of such vaccines might not start until antigens containing the neutralizing epitopes are identified8.