PMC:7055038 / 9364-10566 JSONTXT

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The missing link to the market, the time of travel and onset of symptoms in the two COVID-19 cases together with the incubation period of mean 6.4 days (range: 5.6–7.7) [16] and the time of closest genome neighbours obtained from sequences in Wuhan, suggest that transmission within Wuhan beyond the Huanan Seafood Market is likely to have occurred in the first week of January or earlier. People travelling out of the city since then may have spread the virus further before travel restrictions were enforced on 23 January 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