PMC:7054527 / 7822-9021 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7054527","sourcedb":"PMC","sourceid":"7054527","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7054527","text":"Since 2019-nCoV can be passed directly from person to person by respiratory droplets, emerging evidence suggested that it may also be transmitted through contact and fomites43,48. In addition, the asymptomatic incubation period for individuals infected with 2019-nCov has been reported to be ~1–14 days, and after 24 days individuals were reported, and it was confirmed that those without symptoms can spread the virus4,5,49. To et al. reported that live viruses were present in the saliva of infected individuals by viral culture method43. Furthermore, it has been confirmed that 2019-nCov enters the cell in the same path as SARS coronavirus, that is, through the ACE2 cell receptor25. 2019-nCoV can effectively use ACE2 as a receptor to invade cells, which may promote human-to-human transmission11. ACE2+ cells were found to be abundantly present throughout the respiratory tract, as well as the cells morphologically compatible with salivary gland duct epithelium in human mouth. ACE2+ epithelial cells of salivary gland ducts were demonstrated to be a class early targets of SARS-CoV infection50, and 2019-nCoV is likely to be the same situation, although no research has been reported so 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