PMC:7054527 / 1374-2963 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7054527","sourcedb":"PMC","sourceid":"7054527","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7054527","text":"Introduction\nAn emergent pneumonia outbreak originated in Wuhan City, in the late December 20191. The pneumonia infection has rapidly spread from Wuhan to most other provinces and other 24 countries2,3. World Health Organization declared a public health emergency of international concern over this global pneumonia outbreak on 30th January 2020.\nThe typical clinical symptoms of the patients who suffered from the novel viral pneumonia were fever, cough, and myalgia or fatigue with abnormal chest CT, and the less common symptoms were sputum production, headache, hemoptysis, and diarrhea4–6. This new infectious agent is more likely to affect older males to cause severe respiratory diseases7,8. Some of the clinical symptoms were different from the severe acute respiratory syndrome (SARS) caused by SARS coronavirus (SARS-CoV) that happened in 2002–2003, indicating that a new person-to-person transmission infectious agent has caused this emergent viral pneumonia outbreak8,9. Chinese researchers have quickly isolated a new virus from the patient and sequenced its genome (29,903 nucleotides)10. The infectious agent of this viral pneumonia happenening in Wuhan was finally identified as a novel coronavirus (2019-nCOV), the seventh member of the family of coronaviruses that infect humans11. On 11th February 2020, WHO named the novel viral pneumonia as “Corona Virus Disease (COVID19)”, while the international Committee on Taxonomy of Viruses (ICTV) suggested this novel coronavirus name as “SARS-CoV-2” due to the phylogenetic and taxonomic analysis of this novel coronavirus12.","divisions":[{"label":"title","span":{"begin":0,"end":12}},{"label":"p","span":{"begin":13,"end":346}}],"tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"43","span":{"begin":25,"end":34},"obj":"Disease"},{"id":"44","span":{"begin":102,"end":121},"obj":"Disease"},{"id":"45","span":{"begin":306,"end":315},"obj":"Disease"},{"id":"71","span":{"begin":384,"end":392},"obj":"Species"},{"id":"72","span":{"begin":804,"end":820},"obj":"Species"},{"id":"73","span":{"begin":822,"end":830},"obj":"Species"},{"id":"74","span":{"begin":1046,"end":1053},"obj":"Species"},{"id":"75","span":{"begin":1197,"end":1214},"obj":"Species"},{"id":"76","span":{"begin":1216,"end":1225},"obj":"Species"},{"id":"77","span":{"begin":1264,"end":1277},"obj":"Species"},{"id":"78","span":{"begin":1290,"end":1296},"obj":"Species"},{"id":"79","span":{"begin":1475,"end":1492},"obj":"Species"},{"id":"80","span":{"begin":1502,"end":1512},"obj":"Species"},{"id":"81","span":{"begin":1569,"end":1586},"obj":"Species"},{"id":"82","span":{"begin":421,"end":436},"obj":"Disease"},{"id":"83","span":{"begin":442,"end":447},"obj":"Disease"},{"id":"84","span":{"begin":449,"end":454},"obj":"Disease"},{"id":"85","span":{"begin":460,"end":467},"obj":"Disease"},{"id":"86","span":{"begin":471,"end":478},"obj":"Disease"},{"id":"87","span":{"begin":556,"end":564},"obj":"Disease"},{"id":"88","span":{"begin":566,"end":576},"obj":"Disease"},{"id":"89","span":{"begin":582,"end":590},"obj":"Disease"},{"id":"90","span":{"begin":674,"end":694},"obj":"Disease"},{"id":"91","span":{"begin":954,"end":969},"obj":"Disease"},{"id":"92","span":{"begin":1138,"end":1147},"obj":"Disease"},{"id":"93","span":{"begin":1349,"end":1358},"obj":"Disease"},{"id":"94","span":{"begin":1363,"end":1383},"obj":"Disease"},{"id":"95","span":{"begin":1385,"end":1392},"obj":"Disease"}],"attributes":[{"id":"A43","pred":"tao:has_database_id","subj":"43","obj":"MESH:D011014"},{"id":"A44","pred":"tao:has_database_id","subj":"44","obj":"MESH:D011014"},{"id":"A45","pred":"tao:has_database_id","subj":"45","obj":"MESH:D011014"},{"id":"A71","pred":"tao:has_database_id","subj":"71","obj":"Tax:9606"},{"id":"A72","pred":"tao:has_database_id","subj":"72","obj":"Tax:694009"},{"id":"A73","pred":"tao:has_database_id","subj":"73","obj":"Tax:694009"},{"id":"A74","pred":"tao:has_database_id","subj":"74","obj":"Tax:9606"},{"id":"A75","pred":"tao:has_database_id","subj":"75","obj":"Tax:2697049"},{"id":"A76","pred":"tao:has_database_id","subj":"76","obj":"Tax:2697049"},{"id":"A77","pred":"tao:has_database_id","subj":"77","obj":"Tax:11118"},{"id":"A78","pred":"tao:has_database_id","subj":"78","obj":"Tax:9606"},{"id":"A79","pred":"tao:has_database_id","subj":"79","obj":"Tax:2697049"},{"id":"A80","pred":"tao:has_database_id","subj":"80","obj":"Tax:2697049"},{"id":"A81","pred":"tao:has_database_id","subj":"81","obj":"Tax:2697049"},{"id":"A83","pred":"tao:has_database_id","subj":"83","obj":"MESH:D005334"},{"id":"A84","pred":"tao:has_database_id","subj":"84","obj":"MESH:D003371"},{"id":"A85","pred":"tao:has_database_id","subj":"85","obj":"MESH:D063806"},{"id":"A86","pred":"tao:has_database_id","subj":"86","obj":"MESH:D005221"},{"id":"A87","pred":"tao:has_database_id","subj":"87","obj":"MESH:D006261"},{"id":"A88","pred":"tao:has_database_id","subj":"88","obj":"MESH:D006469"},{"id":"A89","pred":"tao:has_database_id","subj":"89","obj":"MESH:D003967"},{"id":"A90","pred":"tao:has_database_id","subj":"90","obj":"MESH:D012140"},{"id":"A92","pred":"tao:has_database_id","subj":"92","obj":"MESH:D011014"},{"id":"A93","pred":"tao:has_database_id","subj":"93","obj":"MESH:D011014"},{"id":"A94","pred":"tao:has_database_id","subj":"94","obj":"MESH:D018352"},{"id":"A95","pred":"tao:has_database_id","subj":"95","obj":"MESH:C000657245"},{"subj":"43","pred":"source","obj":"LitCovid-PubTator"},{"subj":"44","pred":"source","obj":"LitCovid-PubTator"},{"subj":"45","pred":"source","obj":"LitCovid-PubTator"},{"subj":"71","pred":"source","obj":"LitCovid-PubTator"},{"subj":"72","pred":"source","obj":"LitCovid-PubTator"},{"subj":"73","pred":"source","obj":"LitCovid-PubTator"},{"subj":"74","pred":"source","obj":"LitCovid-PubTator"},{"subj":"75","pred":"source","obj":"LitCovid-PubTator"},{"subj":"76","pred":"source","obj":"LitCovid-PubTator"},{"subj":"77","pred":"source","obj":"LitCovid-PubTator"},{"subj":"78","pred":"source","obj":"LitCovid-PubTator"},{"subj":"79","pred":"source","obj":"LitCovid-PubTator"},{"subj":"80","pred":"source","obj":"LitCovid-PubTator"},{"subj":"81","pred":"source","obj":"LitCovid-PubTator"},{"subj":"82","pred":"source","obj":"LitCovid-PubTator"},{"subj":"83","pred":"source","obj":"LitCovid-PubTator"},{"subj":"84","pred":"source","obj":"LitCovid-PubTator"},{"subj":"85","pred":"source","obj":"LitCovid-PubTator"},{"subj":"86","pred":"source","obj":"LitCovid-PubTator"},{"subj":"87","pred":"source","obj":"LitCovid-PubTator"},{"subj":"88","pred":"source","obj":"LitCovid-PubTator"},{"subj":"89","pred":"source","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