PMC:7039956 / 9452-10180
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7039956","sourcedb":"PMC","sourceid":"7039956","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7039956","text":"In this study, the analysis of public bulk-seq RNA datasets showed that the mucosa of oral cavity could express the ACE2 and was higher in tongue than other oral sites. The results of this study were consistent with the study of Zou et al.10 in general, many organs with higher expression of ACE2 than lung, such as intestine, heart, and kidney. According to the study of Zhao et al.11, the ACE2 expression in lung is concentrated in a small population of type II alveolar cells (AT2), that may cause the relatively low ACE2 expression of lung in bulk-seq RNA datasets analysis. Even though, the result of Zou et al. indicated that the respiratory tract should also be considered as a vulnerable target to 2019-nCoV infection10.","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"289","span":{"begin":116,"end":120},"obj":"Gene"},{"id":"290","span":{"begin":292,"end":296},"obj":"Gene"},{"id":"291","span":{"begin":391,"end":395},"obj":"Gene"},{"id":"292","span":{"begin":520,"end":524},"obj":"Gene"},{"id":"293","span":{"begin":706,"end":725},"obj":"Disease"}],"attributes":[{"id":"A289","pred":"tao:has_database_id","subj":"289","obj":"Gene:59272"},{"id":"A290","pred":"tao:has_database_id","subj":"290","obj":"Gene:59272"},{"id":"A291","pred":"tao:has_database_id","subj":"291","obj":"Gene:59272"},{"id":"A292","pred":"tao:has_database_id","subj":"292","obj":"Gene:59272"},{"id":"A293","pred":"tao:has_database_id","subj":"293","obj":"MESH:C000657245"},{"subj":"289","pred":"source","obj":"LitCovid-PubTator"},{"subj":"290","pred":"source","obj":"LitCovid-PubTator"},{"subj":"291","pred":"source","obj":"LitCovid-PubTator"},{"subj":"292","pred":"source","obj":"LitCovid-PubTator"},{"subj":"293","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T170","span":{"begin":47,"end":50},"obj":"Body_part"},{"id":"T171","span":{"begin":76,"end":82},"obj":"Body_part"},{"id":"T172","span":{"begin":86,"end":97},"obj":"Body_part"},{"id":"T173","span":{"begin":139,"end":145},"obj":"Body_part"},{"id":"T174","span":{"begin":302,"end":306},"obj":"Body_part"},{"id":"T175","span":{"begin":316,"end":325},"obj":"Body_part"},{"id":"T176","span":{"begin":327,"end":332},"obj":"Body_part"},{"id":"T177","span":{"begin":338,"end":344},"obj":"Body_part"},{"id":"T178","span":{"begin":410,"end":414},"obj":"Body_part"},{"id":"T179","span":{"begin":456,"end":478},"obj":"Body_part"},{"id":"T180","span":{"begin":473,"end":478},"obj":"Body_part"},{"id":"T181","span":{"begin":539,"end":543},"obj":"Body_part"},{"id":"T182","span":{"begin":556,"end":559},"obj":"Body_part"},{"id":"T183","span":{"begin":636,"end":653},"obj":"Body_part"}],"attributes":[{"id":"A170","pred":"fma_id","subj":"T170","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A171","pred":"fma_id","subj":"T171","obj":"http://purl.org/sig/ont/fma/fma85355"},{"id":"A172","pred":"fma_id","subj":"T172","obj":"http://purl.org/sig/ont/fma/fma20292"},{"id":"A173","pred":"fma_id","subj":"T173","obj":"http://purl.org/sig/ont/fma/fma54640"},{"id":"A174","pred":"fma_id","subj":"T174","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A175","pred":"fma_id","subj":"T175","obj":"http://purl.org/sig/ont/fma/fma7199"},{"id":"A176","pred":"fma_id","subj":"T176","obj":"http://purl.org/sig/ont/fma/fma7088"},{"id":"A177","pred":"fma_id","subj":"T177","obj":"http://purl.org/sig/ont/fma/fma7203"},{"id":"A178","pred":"fma_id","subj":"T178","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A179","pred":"fma_id","subj":"T179","obj":"http://purl.org/sig/ont/fma/fma62501"},{"id":"A180","pred":"fma_id","subj":"T180","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A181","pred":"fma_id","subj":"T181","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A182","pred":"fma_id","subj":"T182","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A183","pred":"fma_id","subj":"T183","obj":"http://purl.org/sig/ont/fma/fma265130"},{"subj":"T170","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T171","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T172","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T173","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T174","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T175","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T176","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T177","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T178","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T179","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T180","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T181","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T182","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T183","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T63","span":{"begin":76,"end":82},"obj":"Body_part"},{"id":"T64","span":{"begin":86,"end":97},"obj":"Body_part"},{"id":"T65","span":{"begin":139,"end":145},"obj":"Body_part"},{"id":"T66","span":{"begin":259,"end":265},"obj":"Body_part"},{"id":"T67","span":{"begin":302,"end":306},"obj":"Body_part"},{"id":"T68","span":{"begin":316,"end":325},"obj":"Body_part"},{"id":"T69","span":{"begin":327,"end":332},"obj":"Body_part"},{"id":"T70","span":{"begin":338,"end":344},"obj":"Body_part"},{"id":"T71","span":{"begin":410,"end":414},"obj":"Body_part"},{"id":"T72","span":{"begin":539,"end":543},"obj":"Body_part"},{"id":"T73","span":{"begin":636,"end":653},"obj":"Body_part"}],"attributes":[{"id":"A63","pred":"uberon_id","subj":"T63","obj":"http://purl.obolibrary.org/obo/UBERON_0000344"},{"id":"A64","pred":"uberon_id","subj":"T64","obj":"http://purl.obolibrary.org/obo/UBERON_0000167"},{"id":"A65","pred":"uberon_id","subj":"T65","obj":"http://purl.obolibrary.org/obo/UBERON_0001723"},{"id":"A66","pred":"uberon_id","subj":"T66","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"},{"id":"A67","pred":"uberon_id","subj":"T67","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A68","pred":"uberon_id","subj":"T68","obj":"http://purl.obolibrary.org/obo/UBERON_0000160"},{"id":"A69","pred":"uberon_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"A70","pred":"uberon_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"A71","pred":"uberon_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A72","pred":"uberon_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A73","pred":"uberon_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/UBERON_0000065"},{"subj":"T63","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T64","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T65","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T66","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T67","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T68","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T69","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T70","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T71","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T72","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T73","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T185","span":{"begin":76,"end":82},"obj":"http://purl.obolibrary.org/obo/UBERON_0000344"},{"id":"T186","span":{"begin":86,"end":97},"obj":"http://purl.obolibrary.org/obo/UBERON_0000167"},{"id":"T187","span":{"begin":86,"end":97},"obj":"http://www.ebi.ac.uk/efo/EFO_0000825"},{"id":"T188","span":{"begin":139,"end":145},"obj":"http://purl.obolibrary.org/obo/UBERON_0001723"},{"id":"T189","span":{"begin":259,"end":265},"obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"T190","span":{"begin":302,"end":306},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T191","span":{"begin":302,"end":306},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T192","span":{"begin":316,"end":325},"obj":"http://purl.obolibrary.org/obo/UBERON_0000160"},{"id":"T193","span":{"begin":316,"end":325},"obj":"http://www.ebi.ac.uk/efo/EFO_0000834"},{"id":"T194","span":{"begin":327,"end":332},"obj":"http://purl.obolibrary.org/obo/UBERON_0000948"},{"id":"T195","span":{"begin":327,"end":332},"obj":"http://purl.obolibrary.org/obo/UBERON_0007100"},{"id":"T196","span":{"begin":327,"end":332},"obj":"http://purl.obolibrary.org/obo/UBERON_0015228"},{"id":"T197","span":{"begin":327,"end":332},"obj":"http://www.ebi.ac.uk/efo/EFO_0000815"},{"id":"T198","span":{"begin":338,"end":344},"obj":"http://purl.obolibrary.org/obo/UBERON_0002113"},{"id":"T199","span":{"begin":338,"end":344},"obj":"http://www.ebi.ac.uk/efo/EFO_0000927"},{"id":"T200","span":{"begin":338,"end":344},"obj":"http://www.ebi.ac.uk/efo/EFO_0000929"},{"id":"T201","span":{"begin":383,"end":385},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T202","span":{"begin":410,"end":414},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T203","span":{"begin":410,"end":414},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T204","span":{"begin":434,"end":435},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T205","span":{"begin":473,"end":478},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T206","span":{"begin":539,"end":543},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T207","span":{"begin":539,"end":543},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T208","span":{"begin":683,"end":684},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T185","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T186","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T187","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T188","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T189","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T190","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T191","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T192","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T193","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T194","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T195","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T196","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T197","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T198","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T199","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T200","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T201","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T202","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T203","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T204","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T205","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T206","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T207","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T208","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T14","span":{"begin":461,"end":463},"obj":"Chemical"}],"attributes":[{"id":"A14","pred":"chebi_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CHEBI_74067"},{"subj":"T14","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T65","span":{"begin":0,"end":168},"obj":"Sentence"},{"id":"T66","span":{"begin":169,"end":345},"obj":"Sentence"},{"id":"T67","span":{"begin":346,"end":578},"obj":"Sentence"},{"id":"T68","span":{"begin":579,"end":728},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T65","pred":"source","obj":"LitCovid-sentences"},{"subj":"T66","pred":"source","obj":"LitCovid-sentences"},{"subj":"T67","pred":"source","obj":"LitCovid-sentences"},{"subj":"T68","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#99ec93","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#ec93b3"},{"id":"LitCovid-PD-UBERON","color":"#93cdec"},{"id":"LitCovid-PD-CLO","color":"#e7ec93"},{"id":"LitCovid-PD-CHEBI","color":"#d793ec"},{"id":"LitCovid-sentences","color":"#93ecbd"}]}]}}