
PMC:7039956 / 6912-8240
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
185 | 1124-1128 | Gene | denotes | ACE2 | Gene:59272 |
186 | 1158-1162 | Gene | denotes | ACE2 | Gene:59272 |
187 | 1220-1224 | Gene | denotes | ACE2 | Gene:59272 |
188 | 1313-1317 | Gene | denotes | ACE2 | Gene:59272 |
189 | 1205-1211 | Gene | denotes | Violin | |
217 | 159-163 | Gene | denotes | ACE2 | Gene:59272 |
218 | 360-363 | Gene | denotes | SFN | Gene:104444 |
219 | 365-370 | Gene | denotes | KRT6A | Gene:16687 |
220 | 376-381 | Gene | denotes | KRT10 | Gene:16661 |
221 | 420-423 | Gene | denotes | FAP | Gene:14089 |
222 | 425-429 | Gene | denotes | PDPN | Gene:14726 |
223 | 431-437 | Gene | denotes | COL1A2 | Gene:12843 |
224 | 439-442 | Gene | denotes | DCN | Gene:13179 |
225 | 444-450 | Gene | denotes | COL3A1 | Gene:1281 |
226 | 452-458 | Gene | denotes | COL6A1 | Gene:1291 |
227 | 493-496 | Gene | denotes | CD2 | Gene:914 |
228 | 498-502 | Gene | denotes | CD3D | Gene:915 |
229 | 504-508 | Gene | denotes | CD3E | Gene:916 |
230 | 514-518 | Gene | denotes | CD3G | Gene:917 |
231 | 557-562 | Gene | denotes | CD163 | Gene:9332 |
232 | 564-569 | Gene | denotes | CSF1R | Gene:1436 |
233 | 581-587 | Gene | denotes | FCGR2A | Gene:2212 |
234 | 625-629 | Gene | denotes | CMA1 | Gene:1215 |
235 | 631-636 | Gene | denotes | MS4A2 | Gene:2206 |
236 | 638-644 | Gene | denotes | TPSAB1 | Gene:100503895 |
237 | 646-651 | Gene | denotes | TPSB2 | Gene:17229 |
238 | 686-692 | Gene | denotes | SLAMF7 | Gene:75345 |
239 | 694-699 | Gene | denotes | FCRL5 | Gene:329693 |
240 | 705-710 | Gene | denotes | CD79A | Gene:12518 |
241 | 758-764 | Gene | denotes | PECAM1 | Gene:18613 |
242 | 766-769 | Gene | denotes | VWF | Gene:22371 |
243 | 775-778 | Gene | denotes | ENG | Gene:13805 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T112 | 7-11 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T113 | 12-15 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T114 | 47-54 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T115 | 126-130 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T116 | 245-250 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T117 | 271-275 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T118 | 319-335 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
T119 | 330-335 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T120 | 384-395 | Body_part | denotes | fibroblasts | http://purl.org/sig/ont/fma/fma63877 |
T121 | 463-468 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T122 | 521-532 | Body_part | denotes | macrophages | http://purl.org/sig/ont/fma/fma63261 |
T123 | 590-600 | Body_part | denotes | mast cells | http://purl.org/sig/ont/fma/fma66784 |
T124 | 595-600 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T125 | 656-661 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T126 | 716-733 | Body_part | denotes | endothelial cells | http://purl.org/sig/ont/fma/fma66772 |
T127 | 728-733 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T128 | 801-805 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T129 | 825-829 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T130 | 875-879 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T131 | 880-883 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T132 | 905-912 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T133 | 947-951 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T134 | 981-985 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T135 | 995-1000 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T136 | 1045-1049 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T137 | 1074-1078 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T138 | 1113-1118 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T139 | 1253-1257 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T140 | 1284-1290 | Body_part | denotes | tongue | http://purl.org/sig/ont/fma/fma54640 |
T141 | 1291-1307 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
T142 | 1302-1307 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T57 | 1284-1290 | Body_part | denotes | tongue | http://purl.obolibrary.org/obo/UBERON_0001723 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T28 | 420-423 | Disease | denotes | FAP | http://purl.obolibrary.org/obo/MONDO_0021055 |
T29 | 498-502 | Disease | denotes | CD3D | http://purl.obolibrary.org/obo/MONDO_0014280 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T123 | 7-11 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T124 | 126-135 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell type |
T125 | 238-240 | http://purl.obolibrary.org/obo/CLO_0050507 | denotes | 22 |
T126 | 245-250 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T127 | 271-281 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell types |
T128 | 304-306 | http://purl.obolibrary.org/obo/CLO_0001236 | denotes | 2a |
T129 | 319-329 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
T130 | 330-335 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T131 | 344-349 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
T132 | 384-395 | http://purl.obolibrary.org/obo/CL_0000057 | denotes | fibroblasts |
T133 | 404-409 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
T134 | 461-468 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
T135 | 477-482 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
T136 | 541-546 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
T137 | 564-569 | http://purl.obolibrary.org/obo/PR_000002062 | denotes | CSF1R |
T138 | 571-575 | http://purl.obolibrary.org/obo/PR_000002064 | denotes | CD68 |
T139 | 595-600 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T140 | 609-614 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
T141 | 654-661 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B cells |
T142 | 670-675 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
T143 | 716-733 | http://purl.obolibrary.org/obo/CL_0000115 | denotes | endothelial cells |
T144 | 742-747 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | genes |
T145 | 801-805 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T146 | 825-835 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell types |
T147 | 875-879 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T148 | 939-940 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T149 | 947-957 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell types |
T150 | 981-985 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T151 | 995-1000 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T152 | 1032-1033 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | b |
T153 | 1045-1049 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T154 | 1074-1084 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell types |
T155 | 1113-1118 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T156 | 1253-1263 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell types |
T157 | 1284-1290 | http://purl.obolibrary.org/obo/UBERON_0001723 | denotes | tongue |
T158 | 1291-1301 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
T159 | 1302-1307 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T13 | 420-423 | Chemical | denotes | FAP | http://purl.obolibrary.org/obo/CHEBI_73617 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T54 | 0-164 | Sentence | denotes | Single cell RNA-seq was utilized for four oral tissues, and the data was analyzed to confirm the above results and assess the cell type-specific expression of ACE2. |
T55 | 165-780 | Sentence | denotes | After the data preprocessing (shown in section “Materials and methods”), 22 969 cells were acquired and 7 cell types were identified (Fig. 2a), including epithelial cells (marker genes including SFN, KRT6A, and KRT10), fibroblasts (marker genes including FAP, PDPN, COL1A2, DCN, COL3A1, COL6A1), T cells (marker genes including CD2, CD3D, CD3E, and CD3G), macrophages (marker genes including CD163, CSF1R, CD68, and FCGR2A), mast cells (marker genes including CMA1, MS4A2, TPSAB1, TPSB2), B cells (marker genes including SLAMF7, FCRL5, and CD79A) and endothelial cells (marker genes including PECAM1, VWF, and ENG). |
T56 | 781-860 | Sentence | denotes | The heatmap of main cell markers across the cell types can be found in Fig. 2b. |
T57 | 861-1328 | Sentence | denotes | Fig. 2 Single cell RNA-seq analysis of oral tissues from independent dataset. a Seven-cell types were identified by the cell markers; cells were clustered by UMAP method. b Heatmap of cell markers for identifying cell types. c Scatter plots of all the cells with ACE2 expression. d Violin plot of ACE2 expression across different oral sites. e Violin plot of ACE2 expression across different cell types. f Scatter plots of tongue epithelial cells with ACE2 expression |