PMC:7039956 / 4659-6007 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7039956","sourcedb":"PMC","sourceid":"7039956","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7039956","text":"NA-seq profile data of 13 organs including 695 para-carcinoma normal tissues as control from public TCGA were obtained for our analysis, and Fig. 1a showed that ACE2 could be expressed in various organs, the mean expression of different organs could be found in Table 1. According to the mean expression of ACE2, the mucosa of oral cavity could express ACE2, and the results were validated by the data of normal tissues from the FANTOM5 CAGE dataset (Fig. 1b).\nFig. 1 Bulk RNA-seq analysis of public datasets. a Violin plot of ACE2 expression in para-carcinoma normal tissues from TCGA, colored by organs. b Bar plot of ACE2 expression in normal tissues from FANTOM5 CAGE dataset, colored by organs. c Bar plot of ACE2 expression of para-carcinoma normal tissues from TCGA in different oral sites, colored by oral sites; d Boxplot of ACE2 in two kinds of oral sites from TCGA, colored by oral sites\nTable 1 Sample size and ACE2 expression of para-carcinoma normal tissues in different organs\nSample size ACE2 mean expression Standard deviation of expression\nIntestine 51 9.50 1.183\nKidney 129 9.20 2.410\nStomach 35 8.25 3.715\nBile duct 9 7.23 1.163\nLiver 50 6.86 1.351\nOral cavity 32 6.23 1.271\nLung 110 5.83 0.710\nThyroid 59 5.65 0.646\nEsophagus 11 5.31 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