> top > docs > PMC:7036705 > spans > 34-5534 > annotations

PMC:7036705 / 34-5534 JSONTXT

Annnotations TAB JSON ListView MergeView

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
11 121-132 Species denotes Coronavirus Tax:11118
12 154-159 Species denotes human Tax:9606
13 190-200 Species denotes 2019- nCoV Tax:2697049
14 249-258 Species denotes 2019-nCoV Tax:2697049
15 382-388 Species denotes people Tax:9606
16 743-749 Species denotes people Tax:9606
17 219-238 Disease denotes respiratory illness MESH:D012140
20 1007-1023 Species denotes novelcoronavirus Tax:2697049
21 928-934 Disease denotes deaths MESH:D003643
25 1162-1168 Species denotes people Tax:9606
26 1345-1351 Species denotes people Tax:9606
27 1410-1416 Species denotes people Tax:9606
30 1601-1609 Species denotes children Tax:9606
31 1775-1794 Disease denotes respiratory disease MESH:D012140
35 2156-2164 Species denotes patients Tax:9606
36 2205-2213 Species denotes children Tax:9606
37 2246-2266 Disease denotes Coronavirus diseases MESH:D018352
55 2387-2414 Species denotes SARS-associated coronavirus Tax:694009
56 2416-2424 Species denotes SARS-CoV Tax:694009
57 2691-2699 Species denotes patients Tax:9606
58 2830-2838 Species denotes patients Tax:9606
59 2917-2925 Species denotes children Tax:9606
60 3065-3073 Species denotes children Tax:9606
61 3146-3156 Species denotes SARS virus Tax:694009
62 3174-3181 Species denotes patient Tax:9606
63 2989-2995 Chemical denotes oxygen MESH:D010100
64 3015-3033 Chemical denotes methylprednisolone MESH:D008775
65 2268-2301 Disease denotes Severe acute respiratory syndrome MESH:D045169
66 2303-2307 Disease denotes SARS MESH:D045169
67 2443-2451 Disease denotes infected MESH:D007239
68 2536-2540 Disease denotes SARS MESH:D045169
69 2686-2690 Disease denotes SARS MESH:D045169
70 3038-3044 Disease denotes deaths MESH:D003643
71 3094-3098 Disease denotes SARS MESH:D045169
76 3338-3350 Species denotes Corona Virus Tax:11118
77 3406-3414 Species denotes children Tax:9606
78 3267-3299 Disease denotes Middle East Respiratory Syndrome MESH:D018352
79 3301-3305 Disease denotes MERS MESH:D018352
82 3566-3574 Species denotes children Tax:9606
83 3463-3474 Species denotes respiratory Tax:12814
97 3823-3831 Species denotes children Tax:9606
98 3973-3982 Species denotes 2019-nCov Tax:2697049
99 3995-4000 Species denotes child Tax:9606
100 4070-4079 Species denotes 2019-nCov Tax:2697049
101 4124-4131 Species denotes patient Tax:9606
102 4179-4184 Species denotes child Tax:9606
103 4281-4289 Species denotes children Tax:9606
104 3858-3867 Disease denotes infection MESH:D007239
105 3923-3932 Disease denotes infection MESH:D007239
106 4137-4146 Disease denotes pneumonia MESH:D011014
107 4164-4173 Disease denotes infection MESH:D007239
108 4268-4277 Disease denotes infection MESH:D007239
109 4397-4416 Disease denotes respiratory disease MESH:D012140
118 4616-4624 Species denotes children Tax:9606
119 4661-4674 Species denotes Coronaviruses Tax:11118
120 4676-4689 Species denotes Coronaviruses Tax:11118
121 4691-4695 Species denotes CoVs Tax:11118
122 4765-4792 Species denotes respiratory syncytial virus Tax:12814
123 4869-4877 Species denotes children Tax:9606
124 4950-4961 Species denotes respiratory Tax:12814
125 4794-4797 Species denotes RSV Tax:12814
128 5156-5164 Species denotes children Tax:9606
129 5018-5027 Disease denotes pneumonia MESH:D011014
132 5230-5238 Species denotes 2019-CoV Tax:2697049
133 5386-5394 Species denotes children Tax:9606

LitCovid-PMC-OGER-BB

Id Subject Object Predicate Lexical cue
T111 2303-2307 SP_10 denotes SARS
T110 2387-2391 SP_10 denotes SARS
T124 121-132 NCBITaxon:11118 denotes Coronavirus
T123 154-159 SP_6;NCBITaxon:9606 denotes human
T122 190-200 SP_7 denotes 2019- nCoV
T121 249-258 SP_7 denotes 2019-nCoV
T120 382-388 NCBITaxon:9606 denotes people
T119 743-749 NCBITaxon:9606 denotes people
T118 928-934 GO:0016265 denotes deaths
T117 1162-1168 NCBITaxon:9606 denotes people
T116 1345-1351 NCBITaxon:9606 denotes people
T115 1410-1416 NCBITaxon:9606 denotes people
T114 1775-1786 UBERON:0001004 denotes respiratory
T113 2246-2257 NCBITaxon:11118 denotes Coronavirus
T112 2281-2292 UBERON:0001004 denotes respiratory
T109 2403-2414 NCBITaxon:11118 denotes coronavirus
T108 2416-2424 SP_10 denotes SARS-CoV
T107 2452-2463 NCBITaxon:1 denotes individuals
T106 2536-2540 SP_10 denotes SARS
T105 2686-2690 SP_10 denotes SARS
T104 3015-3033 CHEBI:12071;DG_36;CHEBI:12071 denotes methylprednisolone
T103 3038-3044 GO:0016265 denotes deaths
T102 3094-3098 SP_10 denotes SARS
T101 3146-3156 NCBITaxon:10633 denotes SARS virus
T100 3301-3305 SP_9 denotes MERS
T99 3338-3344 NCBITaxon:859912 denotes Corona
T98 3463-3474 UBERON:0001004 denotes respiratory
T97 3973-3982 SP_7 denotes 2019-nCov
T96 4070-4079 SP_7 denotes 2019-nCov
T95 4397-4408 UBERON:0001004 denotes respiratory
T94 4661-4674 NCBITaxon:11118 denotes Coronaviruses
T93 4676-4689 NCBITaxon:11118 denotes Coronaviruses
T92 4691-4695 NCBITaxon:11886 denotes CoVs
T91 4718-4725 NCBITaxon:10239 denotes viruses
T90 4742-4747 UBERON:0000170 denotes lungs
T89 4751-4763 NCBITaxon:7729 denotes rhinoviruses
T88 4765-4776 NCBITaxon:12814;UBERON:0001004 denotes respiratory
T87 4777-4786 NCBITaxon:12814 denotes syncytial
T86 4787-4792 NCBITaxon:10239 denotes virus
T85 4794-4797 NCBITaxon:11886 denotes RSV
T84 4804-4813 NCBITaxon:7719 denotes influenza
T83 4837-4843 SO:0001026 denotes genome
T82 4879-4885 GO:0045087 denotes Innate
T81 4886-4892 GO:0045087;UBERON:0002405 denotes immune
T80 4914-4920 GO:0045087 denotes innate
T79 4921-4927 GO:0045087;UBERON:0002405 denotes immune
T78 4928-4937 GO:0045087 denotes responses
T77 4950-4961 GO:0045333;UBERON:0001004 denotes respiratory
T76 4978-4985 NCBITaxon:10239 denotes viruses
T75 5041-5046 NCBITaxon:10239 denotes virus
T74 5055-5061 UBERON:0002405;GO:0006955 denotes immune
T73 5062-5070 GO:0006955 denotes response
T72 5079-5093 GO:0016271 denotes destruction of
T71 5094-5103 UBERON:0002048 denotes pulmonary
T70 5104-5110 UBERON:0000479 denotes tissue
T69 5183-5190 CHEBI:33695;CHEBI:33695 denotes message

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 4742-4747 Body_part denotes lungs http://purl.org/sig/ont/fma/fma68877
T2 4833-4836 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T3 4837-4843 Body_part denotes genome http://purl.org/sig/ont/fma/fma84116
T4 4973-4976 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T5 5104-5110 Body_part denotes tissue http://purl.org/sig/ont/fma/fma9637

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 5104-5110 Body_part denotes tissue http://purl.obolibrary.org/obo/UBERON_0000479

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 1775-1794 Disease denotes respiratory disease http://purl.obolibrary.org/obo/MONDO_0005087
T2 2268-2301 Disease denotes Severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T3 2303-2307 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T4 2387-2391 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T5 2416-2424 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T6 2416-2420 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T7 2536-2540 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T8 2686-2690 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T9 3094-3098 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T10 3146-3150 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T11 3858-3867 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T12 3923-3932 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T13 4137-4146 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249
T14 4164-4173 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T15 4268-4277 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T16 4397-4416 Disease denotes respiratory disease http://purl.obolibrary.org/obo/MONDO_0005087
T17 4804-4813 Disease denotes influenza http://purl.obolibrary.org/obo/MONDO_0005812
T18 5018-5027 Disease denotes pneumonia http://purl.obolibrary.org/obo/MONDO_0005249

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 0-1 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T2 154-159 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T3 563-564 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T4 948-949 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 1004-1006 http://purl.obolibrary.org/obo/CLO_0037161 denotes en
T6 1052-1055 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T7 1234-1237 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T8 1258-1259 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T9 1821-1824 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T10 1834-1835 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T11 2002-2003 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T12 2114-2116 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T13 2124-2126 http://purl.obolibrary.org/obo/CLO_0001022 denotes Li
T14 2124-2126 http://purl.obolibrary.org/obo/CLO_0007314 denotes Li
T15 2476-2478 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T16 2497-2498 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T17 2726-2728 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T18 3151-3156 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T19 3162-3163 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T20 3345-3350 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes Virus
T21 3534-3535 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T22 3993-3994 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T23 4001-4004 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T24 4122-4123 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T25 4177-4178 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T26 4322-4331 http://www.ebi.ac.uk/efo/EFO_0000876 denotes extremely
T27 4718-4725 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T28 4742-4747 http://www.ebi.ac.uk/efo/EFO_0000934 denotes lungs
T29 4787-4792 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T30 4978-4985 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes viruses
T31 5041-5046 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T32 5169-5170 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T33 5413-5414 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T34 5485-5486 http://purl.obolibrary.org/obo/CLO_0001020 denotes a

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 1004-1006 Chemical denotes en http://purl.obolibrary.org/obo/CHEBI_30347
T2 2124-2126 Chemical denotes Li http://purl.obolibrary.org/obo/CHEBI_30145
T3 2989-2995 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T4 3015-3033 Chemical denotes methylprednisolone http://purl.obolibrary.org/obo/CHEBI_6888

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 515-523 http://purl.obolibrary.org/obo/GO_0015297 denotes exchange
T2 4886-4900 http://purl.obolibrary.org/obo/GO_0042783 denotes immune evasion
T3 4914-4937 http://purl.obolibrary.org/obo/GO_0045087 denotes innate immune responses
T4 5055-5070 http://purl.obolibrary.org/obo/GO_0006955 denotes immune response

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T3 0-62 Sentence denotes A novel epidemic is challenging the global health care system.
T4 63-319 Sentence denotes Starting from probably November to December 2019, another Coronavirus entered the arena of human pathogens, to be then defined 2019- nCoV.1 The outbreak of respiratory illness caused by 2019-nCoV was initially detected in Wuhan City, Hubei Province, China.
T5 320-401 Sentence denotes China Republic arranged strong restrictions to limit domestic people circulation.
T6 402-633 Sentence denotes Within days, most European countries and the United States established an unrestricted scientific cooperation to exchange data and information, useful to design a defensive wall against the worldwide spreading of this new epidemic.
T7 634-852 Sentence denotes Spreading is favored by universal access to intercontinental mobility by airplane, and propensity of Chinese people to massively migrate within, but also outside, their subcontinent especially during national holidays.
T8 853-1031 Sentence denotes As of February 5, 2020, the number of confirmed cases was 24,554, with 492 deaths resulting in a crude fatality rate of 2% (https://www.ecdc.europa.eu/en/novelcoronavirus-china).
T9 1032-1156 Sentence denotes Spreading in Europe has been likely slowed down so far by the international coordinated effort, with only 28 cases reported.
T10 1157-1211 Sentence denotes Yet, people are scared by this novel, unknown disease.
T11 1212-1365 Sentence denotes Their daily lifestyle has been affected, with a marked decrease of unnecessary trips abroad, and reduction of events causing massive people accumulation.
T12 1366-1465 Sentence denotes Basic sanitary checks have been enforced on people entering European countries directly from China.
T13 1466-1542 Sentence denotes Questions have been raised even on the opportunity to keep the schools open.
T14 1543-1610 Sentence denotes The fear of unknown diseases is obviously even higher for children.
T15 1611-1795 Sentence denotes As an immediate result, parents are taking their kids to the emergency room of their local hospital more often and in the presence of minimal signs and symptoms of respiratory disease.
T16 1796-1920 Sentence denotes The public health system has arranged a sanitary chain to isolate and quickly screen all possible, but even suspected cases.
T17 1921-2019 Sentence denotes However, this emergency belt might result expensive and hard to be sustained for a very long time.
T18 2020-2267 Sentence denotes In their report of the characteristics of the first 425 cases observed in Wuhan as of January 22, 2020, Li et al. show that none of the patients had less than 15 years of age.2 Is this children-sparing pattern common to other Coronavirus diseases?
T19 2268-2426 Sentence denotes Severe acute respiratory syndrome (SARS) spread in Hong-Kong and then worldwide from March to June 2003, caused by the SARS-associated coronavirus (SARS-CoV).
T20 2427-2626 Sentence denotes Among over 1700 infected individuals, 6.9% were <18 years of age with a case fatality rate of 0%. (Source: e-SARS database, Hospital Authority, Hong Kong Special Administrative Region, data on file).
T21 2627-3034 Sentence denotes In their analysis of 6 case series reporting 135 pediatric SARS patients (80 laboratory-confirmed, 27 probable and 28 suspect) from Canada, Hong Kong, Taiwan and Singapore, Stockman et al. reported that patients 12 years of age or younger had milder disease and were less likely than older children to be admitted to an intensive care unit, receive supplemental oxygen or be treated with methylprednisolone.
T22 3035-3227 Sentence denotes No deaths were reported among children or adolescents with SARS.3 Only one published report of transmission of SARS virus from a pediatric patient was available at the time of writing in 2007.
T23 3228-3416 Sentence denotes In their retrospective analysis of the Middle East Respiratory Syndrome (MERS) spread in 2012, also caused by Corona Virus, Azhar et al. report that only 2% of cases occurred in children.4
T24 3417-3575 Sentence denotes This clearly shows that three different acute respiratory syndromes developed as epidemic in the last decades showed a reduced propensity to involve children.
T25 3576-3781 Sentence denotes Coming to the hottest topic, data from Wuhan show that at an early evaluation, the pediatric population, even in this very-high risk area, appears to be at an unexpectedly low risk to develop the disease.2
T26 3782-3818 Sentence denotes Why may this happen remains unclear.
T27 3819-3933 Sentence denotes Are children absolutely protected from infection or only from the risk to develop the disease following infection?
T28 3934-4033 Sentence denotes Formal demonstration of the ability of 2019-nCov to infect a child has been provided by Chan et al.
T29 4034-4440 Sentence denotes In their report, when screening for 2019-nCov the asymptomatic members of the family of a patient with pneumonia, they documented infection in a child who yet remained asymptomatic.5 Thus, this first and so far unique case shows that infection of children is possible although apparently extremely rare; furthermore, it was not followed by the development of the respiratory disease at the time of writing.
T30 4441-4545 Sentence denotes Persistence of maternal protective immunity extending to the entire pediatric age appears very unlikely.
T31 4546-4611 Sentence denotes No other positively protective effect may be easily hypothesized.
T32 4612-4675 Sentence denotes Are children cross-protected by having met other Coronaviruses?
T33 4676-4878 Sentence denotes Coronaviruses (CoVs) is one of the common viruses that invade the lungs as rhinoviruses, respiratory syncytial virus (RSV), and influenza, which all have an RNA genome and are very frequent in children.
T34 4879-4987 Sentence denotes Innate immune evasion links to the innate immune responses elicited by respiratory and other (RNA) viruses.6
T35 4988-5165 Sentence denotes One explanation could be that pneumonia results from virus-induced immune response causing destruction of pulmonary tissue.7 Such mechanisms could be less effective in children.
T36 5166-5500 Sentence denotes As a bottom-line message, although we do not know how massively 2019-CoV will spread and affect the population worldwide, we may try to reassure the population about the real risk represented by this novel ordeal: their children are apparently at a minimal risk to develop this new disease, and at virtually no risk of a fatal course.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 219-238 Phenotype denotes respiratory illness http://purl.obolibrary.org/obo/HP_0002086
T2 4137-4146 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090
T3 5018-5027 Phenotype denotes pneumonia http://purl.obolibrary.org/obo/HP_0002090