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LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
60 4830-4836 Chemical denotes oxygen MESH:D010100
2 57-65 Species denotes Patients Tax:9606
3 23-43 Disease denotes SARS-CoV-2 Infection MESH:C000657245
10 106-153 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
11 155-165 Species denotes SARS-CoV-2 Tax:2697049
12 547-555 Species denotes patients Tax:9606
13 694-704 Species denotes SARS-CoV-2 Tax:2697049
14 792-800 Species denotes SARS-CoV Tax:694009
15 761-783 Disease denotes coronavirus infections MESH:D018352
24 884-931 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
25 933-943 Species denotes SARS-CoV-2 Tax:2697049
26 1113-1121 Species denotes patients Tax:9606
27 1200-1210 Species denotes SARS-CoV-2 Tax:2697049
28 1517-1522 Species denotes human Tax:9606
29 1581-1589 Species denotes patients Tax:9606
30 828-853 Disease denotes novel coronavirus disease MESH:C000657245
31 855-863 Disease denotes COVID-19 MESH:C000657245
36 1707-1715 Species denotes patients Tax:9606
37 2165-2175 Species denotes SARS-CoV-2 Tax:2697049
38 2289-2299 Species denotes SARS-CoV-2 Tax:2697049
39 1749-1769 Disease denotes SARS-CoV-2 infection MESH:C000657245
54 2510-2515 Species denotes woman Tax:9606
55 2655-2662 Species denotes patient Tax:9606
56 2720-2727 Species denotes Patient Tax:9606
57 3425-3435 Species denotes SARS-CoV-2 Tax:2697049
58 3662-3668 Chemical denotes oxygen MESH:D010100
59 4073-4079 Chemical denotes oxygen MESH:D010100
61 2560-2579 Disease denotes SARS-CoV-2 infected MESH:C000657245
62 2865-2870 Disease denotes fever MESH:D005334
63 2979-2984 Disease denotes fever MESH:D005334
64 2998-3005 Disease denotes myalgia MESH:D063806
65 3185-3205 Disease denotes respiratory symptoms MESH:D012818
66 3558-3569 Disease denotes sub-pleural MESH:D010995
67 3734-3739 Disease denotes cough MESH:D003371
78 4972-4979 Species denotes Patient Tax:9606
79 5161-5168 Species denotes patient Tax:9606
80 5844-5851 Species denotes patient Tax:9606
81 5915-5925 Species denotes SARS-CoV-2 Tax:2697049
82 6096-6103 Species denotes Patient Tax:9606
83 6227-6237 Species denotes SARS-CoV-2 Tax:2697049
84 5279-5290 Disease denotes sore throat MESH:D010608
85 5308-5315 Disease denotes myalgia MESH:D063806
86 5445-5465 Disease denotes SARS-CoV-2 infection MESH:C000657245
87 6358-6363 Disease denotes cough MESH:D003371
110 7016-7024 Species denotes patients Tax:9606
111 7136-7144 Species denotes patients Tax:9606
112 7185-7195 Species denotes SARS-CoV-2 Tax:2697049
113 7324-7329 Species denotes human Tax:9606
114 7334-7341 Species denotes Patient Tax:9606
115 7892-7899 Species denotes Patient Tax:9606
116 8520-8527 Species denotes patient Tax:9606
117 8833-8841 Species denotes MERS-CoV Tax:1335626
118 9097-9104 Species denotes patient Tax:9606
119 9190-9200 Species denotes SARS-CoV-2 Tax:2697049
120 7414-7420 Chemical denotes oxygen MESH:D010100
121 8433-8439 Chemical denotes oxygen MESH:D010100
122 7305-7320 Disease denotes virus infection MESH:D001102
123 7390-7409 Disease denotes shortness of breath MESH:D004417
124 7716-7734 Disease denotes SARS-CoV infection MESH:C000657245
125 7848-7853 Disease denotes fever MESH:D005334
126 7858-7865 Disease denotes myalgia MESH:D063806
127 7983-7988 Disease denotes cough MESH:D003371
128 8000-8019 Disease denotes shortness of breath MESH:D004417
129 8401-8406 Disease denotes cough MESH:D003371
130 8408-8427 Disease denotes shortness of breath MESH:D004417
131 9124-9133 Disease denotes infection MESH:D007239
139 9315-9322 Species denotes Patient Tax:9606
140 9550-9557 Species denotes patient Tax:9606
141 9627-9634 Species denotes patient Tax:9606
142 9759-9766 Species denotes patient Tax:9606
143 10114-10121 Species denotes patient Tax:9606
144 9654-9665 Disease denotes sore throat MESH:D010608
145 10147-10152 Disease denotes cough MESH:D003371
157 10293-10301 Species denotes patients Tax:9606
158 10350-10358 Species denotes patients Tax:9606
159 10475-10483 Species denotes patients Tax:9606
160 10757-10767 Species denotes SARS-CoV-2 Tax:2697049
161 10841-10849 Species denotes patients Tax:9606
162 11515-11523 Species denotes patients Tax:9606
163 11617-11625 Species denotes patients Tax:9606
164 10438-10457 Chemical denotes Lopinavir/ritonavir MESH:C558899
165 10640-10659 Chemical denotes Lopinavir/ritonavir MESH:C558899
166 10681-10689 Disease denotes diarrhea MESH:D003967
167 11495-11514 Disease denotes SARS-CoV-2 infected MESH:C000657245
170 11747-11757 Species denotes SARS-CoV-2 Tax:2697049
171 11813-11821 Species denotes patients Tax:9606
173 12057-12065 Species denotes patients Tax:9606
175 13320-13322 CellLine denotes SY CVCL:7028
177 13377-13379 CellLine denotes SY CVCL:7028
179 13431-13433 CellLine denotes SY CVCL:7028
181 13605-13607 CellLine denotes SY CVCL:7028
212 14876-14884 Species denotes patients Tax:9606
213 14942-14949 Species denotes Patient Tax:9606
214 15000-15007 Species denotes Patient Tax:9606
215 14856-14875 Disease denotes SARS-CoV-2 infected MESH:C000657245
218 15165-15175 Species denotes SARS-CoV-2 Tax:2697049
219 15178-15225 Species denotes severe acute respiratory syndrome coronavirus 2 Tax:2697049
227 15232-15239 Species denotes Patient Tax:9606
228 15487-15494 Species denotes Patient Tax:9606
229 15534-15553 Chemical denotes Lopinavir/ritonavir MESH:C558899
230 15253-15258 Disease denotes fever MESH:D005334
231 15365-15372 Disease denotes myalgia MESH:D063806
232 15377-15388 Disease denotes sore throat MESH:D010608
233 15465-15470 Disease denotes fever MESH:D005334

LitCovid-PD-FMA-UBERON

Id Subject Object Predicate Lexical cue fma_id
T1 1517-1527 Body_part denotes human body http://purl.org/sig/ont/fma/fma305853
T2 1600-1623 Body_part denotes Upper respiratory tract http://purl.org/sig/ont/fma/fma45661
T3 1625-1628 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T4 1662-1665 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T5 1933-1936 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T6 1951-1957 Body_part denotes sputum http://purl.org/sig/ont/fma/fma312401
T7 1970-1973 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T8 1985-1990 Body_part denotes Serum http://purl.org/sig/ont/fma/fma63083
T9 1992-1998 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T10 2000-2005 Body_part denotes urine http://purl.org/sig/ont/fma/fma12274
T11 2011-2016 Body_part denotes stool http://purl.org/sig/ont/fma/fma64183
T12 2270-2273 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T13 2757-2760 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T14 3112-3115 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T15 3207-3210 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T16 3233-3239 Body_part denotes sputum http://purl.org/sig/ont/fma/fma312401
T17 3360-3365 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T18 3395-3398 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T19 3562-3576 Body_part denotes pleural spaces http://purl.org/sig/ont/fma/fma9740
T20 3632-3635 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T21 3902-3905 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T22 3910-3913 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T23 3985-3988 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T24 4008-4011 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T25 4257-4262 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T26 4352-4355 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T27 4378-4381 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T28 4480-4485 Body_part denotes stool http://purl.org/sig/ont/fma/fma64183
T29 4531-4535 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T30 4568-4573 Body_part denotes urine http://purl.org/sig/ont/fma/fma12274
T31 4578-4583 Body_part denotes stool http://purl.org/sig/ont/fma/fma64183
T32 4685-4690 Body_part denotes serum http://purl.org/sig/ont/fma/fma63083
T33 5284-5290 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T34 5643-5648 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T35 5779-5782 Body_part denotes RNA http://purl.org/sig/ont/fma/fma67095
T36 5947-5950 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T37 5955-5958 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T38 6047-6050 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T39 6077-6080 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T40 6132-6135 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T41 6164-6167 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T42 6301-6304 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T43 6309-6312 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T44 6382-6388 Body_part denotes sputum http://purl.org/sig/ont/fma/fma312401
T45 6390-6393 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T46 6447-6450 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T47 6470-6473 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T48 6649-6652 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T49 6731-6735 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T50 6746-6752 Body_part denotes plasma http://purl.org/sig/ont/fma/fma62970
T51 6757-6762 Body_part denotes stool http://purl.org/sig/ont/fma/fma64183
T52 8342-8345 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T53 8387-8390 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T54 8553-8556 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T55 8649-8652 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T56 8666-8671 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T57 8743-8746 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T58 8751-8754 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T59 8885-8888 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T60 8934-8937 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T61 8942-8945 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T62 9018-9022 Body_part denotes gene http://purl.org/sig/ont/fma/fma74402
T63 9040-9045 Body_part denotes urine http://purl.org/sig/ont/fma/fma12274
T64 9050-9055 Body_part denotes stool http://purl.org/sig/ont/fma/fma64183
T65 9287-9292 Body_part denotes urine http://purl.org/sig/ont/fma/fma12274
T66 9297-9302 Body_part denotes stool http://purl.org/sig/ont/fma/fma64183
T67 9659-9665 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T68 9862-9865 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T69 9870-9873 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T70 9951-9954 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T71 9999-10002 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T72 10060-10063 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T73 10190-10196 Body_part denotes sputum http://purl.org/sig/ont/fma/fma312401
T74 10703-10725 Body_part denotes gastrointestinal tract http://purl.org/sig/ont/fma/fma71132
T75 11776-11779 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T76 11784-11787 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T77 13259-13263 Body_part denotes Chin http://purl.org/sig/ont/fma/fma46495
T78 13299-13303 Body_part denotes Chin http://purl.org/sig/ont/fma/fma46495
T79 13356-13360 Body_part denotes Chin http://purl.org/sig/ont/fma/fma46495
T80 13485-13489 Body_part denotes Chin http://purl.org/sig/ont/fma/fma46495
T81 13609-13613 Body_part denotes Chin http://purl.org/sig/ont/fma/fma46495
T82 14225-14230 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T83 14268-14273 Body_part denotes urine http://purl.org/sig/ont/fma/fma12274
T84 14278-14283 Body_part denotes stool http://purl.org/sig/ont/fma/fma64183
T85 14489-14494 Body_part denotes blood http://purl.org/sig/ont/fma/fma9670
T86 14532-14537 Body_part denotes urine http://purl.org/sig/ont/fma/fma12274
T87 14542-14547 Body_part denotes stool http://purl.org/sig/ont/fma/fma64183
T88 14604-14609 Body_part denotes Chest http://purl.org/sig/ont/fma/fma9576
T89 15011-15014 Body_part denotes URT http://purl.org/sig/ont/fma/fma45661
T90 15017-15040 Body_part denotes upper respiratory tract http://purl.org/sig/ont/fma/fma45661
T91 15042-15045 Body_part denotes LRT http://purl.org/sig/ont/fma/fma273029
T92 15048-15071 Body_part denotes lower respiratory tract http://purl.org/sig/ont/fma/fma45662
T93 15098-15103 Body_part denotes chest http://purl.org/sig/ont/fma/fma9576
T94 15382-15388 Body_part denotes throat http://purl.org/sig/ont/fma/fma228738
T95 15515-15520 Body_part denotes stool http://purl.org/sig/ont/fma/fma64183

LitCovid-PD-UBERON

Id Subject Object Predicate Lexical cue uberon_id
T1 1600-1623 Body_part denotes Upper respiratory tract http://purl.obolibrary.org/obo/UBERON_0001557
T2 1606-1623 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T3 1625-1628 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T4 1925-1929 Body_part denotes tube http://purl.obolibrary.org/obo/UBERON_0000025
T5 1933-1936 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T6 1951-1957 Body_part denotes sputum http://purl.obolibrary.org/obo/UBERON_0007311
T7 1985-1990 Body_part denotes Serum http://purl.obolibrary.org/obo/UBERON_0001977
T8 2000-2005 Body_part denotes urine http://purl.obolibrary.org/obo/UBERON_0001088
T9 2011-2016 Body_part denotes stool http://purl.obolibrary.org/obo/UBERON_0001988
T10 3112-3115 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T11 3233-3239 Body_part denotes sputum http://purl.obolibrary.org/obo/UBERON_0007311
T12 3360-3365 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T13 3902-3905 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T14 4008-4011 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T15 4257-4262 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T16 4378-4381 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T17 4480-4485 Body_part denotes stool http://purl.obolibrary.org/obo/UBERON_0001988
T18 4568-4573 Body_part denotes urine http://purl.obolibrary.org/obo/UBERON_0001088
T19 4578-4583 Body_part denotes stool http://purl.obolibrary.org/obo/UBERON_0001988
T20 4685-4690 Body_part denotes serum http://purl.obolibrary.org/obo/UBERON_0001977
T21 5284-5290 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T22 5643-5648 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T23 5947-5950 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T24 6047-6050 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T25 6132-6135 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T26 6301-6304 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T27 6382-6388 Body_part denotes sputum http://purl.obolibrary.org/obo/UBERON_0007311
T28 6447-6450 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T29 6649-6652 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T30 6757-6762 Body_part denotes stool http://purl.obolibrary.org/obo/UBERON_0001988
T31 8666-8671 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T32 8743-8746 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T33 8934-8937 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T34 9040-9045 Body_part denotes urine http://purl.obolibrary.org/obo/UBERON_0001088
T35 9050-9055 Body_part denotes stool http://purl.obolibrary.org/obo/UBERON_0001988
T36 9287-9292 Body_part denotes urine http://purl.obolibrary.org/obo/UBERON_0001088
T37 9297-9302 Body_part denotes stool http://purl.obolibrary.org/obo/UBERON_0001988
T38 9659-9665 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T39 9862-9865 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T40 9951-9954 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T41 10060-10063 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T42 10190-10196 Body_part denotes sputum http://purl.obolibrary.org/obo/UBERON_0007311
T43 11776-11779 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T44 13259-13263 Body_part denotes Chin http://purl.obolibrary.org/obo/UBERON_0008199
T45 13299-13303 Body_part denotes Chin http://purl.obolibrary.org/obo/UBERON_0008199
T46 13356-13360 Body_part denotes Chin http://purl.obolibrary.org/obo/UBERON_0008199
T47 13485-13489 Body_part denotes Chin http://purl.obolibrary.org/obo/UBERON_0008199
T48 13609-13613 Body_part denotes Chin http://purl.obolibrary.org/obo/UBERON_0008199
T49 14225-14230 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T50 14268-14273 Body_part denotes urine http://purl.obolibrary.org/obo/UBERON_0001088
T51 14278-14283 Body_part denotes stool http://purl.obolibrary.org/obo/UBERON_0001988
T52 14489-14494 Body_part denotes blood http://purl.obolibrary.org/obo/UBERON_0000178
T53 14532-14537 Body_part denotes urine http://purl.obolibrary.org/obo/UBERON_0001088
T54 14542-14547 Body_part denotes stool http://purl.obolibrary.org/obo/UBERON_0001988
T55 14604-14609 Body_part denotes Chest http://purl.obolibrary.org/obo/UBERON_0001443
T56 15011-15014 Body_part denotes URT http://purl.obolibrary.org/obo/UBERON_0001557
T57 15017-15040 Body_part denotes upper respiratory tract http://purl.obolibrary.org/obo/UBERON_0001557
T58 15023-15040 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T59 15048-15071 Body_part denotes lower respiratory tract http://purl.obolibrary.org/obo/UBERON_0001558
T60 15054-15071 Body_part denotes respiratory tract http://purl.obolibrary.org/obo/UBERON_0000065
T61 15098-15103 Body_part denotes chest http://purl.obolibrary.org/obo/UBERON_0001443
T62 15382-15388 Body_part denotes throat http://purl.obolibrary.org/obo/UBERON_0000341
T63 15515-15520 Body_part denotes stool http://purl.obolibrary.org/obo/UBERON_0001988

LitCovid-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T1 23-31 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T2 34-43 Disease denotes Infection http://purl.obolibrary.org/obo/MONDO_0005550
T3 106-153 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T4 106-139 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T5 155-163 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T6 694-702 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T7 773-783 Disease denotes infections http://purl.obolibrary.org/obo/MONDO_0005550
T8 792-800 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T9 855-863 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T10 884-931 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T11 884-917 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T12 933-941 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T13 1200-1208 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T14 1749-1757 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T15 1760-1769 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T16 2165-2173 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T17 2289-2297 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T18 2560-2568 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T19 3425-3433 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T20 4474-4485 Disease denotes loose stool http://purl.obolibrary.org/obo/MONDO_0001673
T21 5216-5218 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T22 5279-5290 Disease denotes sore throat http://purl.obolibrary.org/obo/MONDO_0002258
T23 5445-5453 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T24 5456-5465 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T25 5915-5923 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T26 6227-6235 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T27 6341-6343 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T28 6897-6899 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T29 7185-7193 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T30 7305-7320 Disease denotes virus infection http://purl.obolibrary.org/obo/MONDO_0005108
T31 7311-7320 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T32 7716-7734 Disease denotes SARS-CoV infection http://purl.obolibrary.org/obo/MONDO_0005091
T33 7725-7734 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T34 9124-9133 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T35 9190-9198 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T36 9654-9665 Disease denotes sore throat http://purl.obolibrary.org/obo/MONDO_0002258
T37 10681-10689 Disease denotes diarrhea http://purl.obolibrary.org/obo/MONDO_0001673
T38 10757-10765 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T39 11244-11254 Disease denotes infectious http://purl.obolibrary.org/obo/MONDO_0005550
T40 11495-11503 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T41 11747-11755 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T42 12685-12694 Disease denotes infection http://purl.obolibrary.org/obo/MONDO_0005550
T43 12897-12907 Disease denotes Infectious http://purl.obolibrary.org/obo/MONDO_0005550
T44 12955-12965 Disease denotes Infectious http://purl.obolibrary.org/obo/MONDO_0005550
T45 13055-13063 Disease denotes COVID-19 http://purl.obolibrary.org/obo/MONDO_0100096
T46 13264-13266 Disease denotes BS http://purl.obolibrary.org/obo/MONDO_0008876
T47 13304-13306 Disease denotes BS http://purl.obolibrary.org/obo/MONDO_0008876
T48 13361-13363 Disease denotes BS http://purl.obolibrary.org/obo/MONDO_0008876
T49 13490-13492 Disease denotes BS http://purl.obolibrary.org/obo/MONDO_0008876
T50 13614-13616 Disease denotes BS http://purl.obolibrary.org/obo/MONDO_0008876
T51 14856-14864 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T52 15165-15173 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T53 15178-15225 Disease denotes severe acute respiratory syndrome coronavirus 2 http://purl.obolibrary.org/obo/MONDO_0100096
T54 15178-15211 Disease denotes severe acute respiratory syndrome http://purl.obolibrary.org/obo/MONDO_0005091
T55 15299-15301 Disease denotes he http://purl.obolibrary.org/obo/MONDO_0017319
T56 15377-15388 Disease denotes sore throat http://purl.obolibrary.org/obo/MONDO_0002258
T57 15509-15520 Disease denotes loose stool http://purl.obolibrary.org/obo/MONDO_0001673

LitCovid-PD-CLO

Id Subject Object Predicate Lexical cue
T1 210-213 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T2 979-982 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T3 1174-1186 http://purl.obolibrary.org/obo/OBI_0000245 denotes Organization
T4 1220-1221 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T5 1424-1429 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T6 1508-1513 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T7 1517-1522 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T8 1829-1834 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T9 1925-1929 http://purl.obolibrary.org/obo/UBERON_0000025 denotes tube
T10 1992-1998 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T11 2407-2412 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tests
T12 2488-2489 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T13 2490-2492 http://purl.obolibrary.org/obo/CLO_0001000 denotes 35
T14 2629-2630 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T15 3049-3051 http://purl.obolibrary.org/obo/CLO_0050510 denotes 18
T16 3088-3093 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T17 3259-3265 http://purl.obolibrary.org/obo/UBERON_0001005 denotes airway
T18 3360-3365 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T19 4249-4250 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T20 4257-4262 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T21 4531-4535 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T22 4986-4987 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T23 5091-5093 http://purl.obolibrary.org/obo/CLO_0050507 denotes 22
T24 5135-5136 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T25 5402-5408 http://purl.obolibrary.org/obo/UBERON_0000473 denotes tested
T26 5643-5648 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T27 5865-5873 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test was
T28 6181-6189 http://purl.obolibrary.org/obo/UBERON_0000473 denotes test was
T29 6251-6252 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T30 6424-6425 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T31 6615-6620 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T32 6731-6735 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T33 6746-6752 http://purl.obolibrary.org/obo/UBERON_0001969 denotes plasma
T34 6781-6786 http://purl.obolibrary.org/obo/OGG_0000000002 denotes genes
T35 6922-6924 http://purl.obolibrary.org/obo/CLO_0050509 denotes 27
T36 7305-7310 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T37 7324-7329 http://purl.obolibrary.org/obo/NCBITaxon_9606 denotes human
T38 7813-7816 http://purl.obolibrary.org/obo/CLO_0001000 denotes 3–5
T39 8162-8163 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T40 8318-8323 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T41 8571-8576 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T42 8666-8671 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T43 8876-8881 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T44 9018-9022 http://purl.obolibrary.org/obo/OGG_0000000002 denotes gene
T45 9572-9575 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T46 9625-9626 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T47 9757-9758 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T48 9830-9835 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T49 10018-10023 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T50 10214-10221 http://purl.obolibrary.org/obo/UBERON_0000473 denotes testing
T51 10703-10725 http://purl.obolibrary.org/obo/UBERON_0005409 denotes gastrointestinal tract
T52 10866-10871 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T53 10906-10911 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T54 11002-11007 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T55 11090-11095 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T56 11096-11099 http://purl.obolibrary.org/obo/CLO_0051582 denotes has
T57 11228-11233 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T58 11315-11320 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T59 11362-11367 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T60 11387-11388 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T61 11695-11700 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T62 11727-11728 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T63 11966-11971 http://purl.obolibrary.org/obo/NCBITaxon_10239 denotes virus
T64 12780-12781 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T65 13405-13407 http://purl.obolibrary.org/obo/CLO_0007029 denotes JM
T66 13405-13407 http://purl.obolibrary.org/obo/CLO_0050993 denotes JM
T67 13571-13573 http://purl.obolibrary.org/obo/CLO_0007029 denotes JM
T68 13571-13573 http://purl.obolibrary.org/obo/CLO_0050993 denotes JM
T69 14150-14151 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T70 14199-14200 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T71 14225-14230 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T72 14225-14230 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T73 14414-14415 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T74 14463-14464 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T75 14489-14494 http://purl.obolibrary.org/obo/UBERON_0000178 denotes blood
T76 14489-14494 http://www.ebi.ac.uk/efo/EFO_0000296 denotes blood
T77 14597-14603 http://purl.obolibrary.org/obo/CLO_0001236 denotes 2. (A)
T78 14604-14609 http://www.ebi.ac.uk/efo/EFO_0000965 denotes Chest
T79 14683-14684 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T80 14896-14897 http://purl.obolibrary.org/obo/CLO_0001020 denotes A
T81 14954-14955 http://purl.obolibrary.org/obo/CLO_0001021 denotes B
T82 15048-15071 http://purl.obolibrary.org/obo/UBERON_0001558 denotes lower respiratory tract
T83 15098-15103 http://www.ebi.ac.uk/efo/EFO_0000965 denotes chest
T84 15227-15228 http://purl.obolibrary.org/obo/CLO_0001020 denotes a
T85 15485-15486 http://purl.obolibrary.org/obo/CLO_0001021 denotes b

LitCovid-PD-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T1 3662-3668 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T2 4073-4079 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T3 4830-4836 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T4 5357-5393 Chemical denotes nonsteroidal anti-inflammatory agent http://purl.obolibrary.org/obo/CHEBI_35475
T5 5370-5393 Chemical denotes anti-inflammatory agent http://purl.obolibrary.org/obo/CHEBI_67079
T6 7414-7420 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T7 8231-8240 Chemical denotes antiviral http://purl.obolibrary.org/obo/CHEBI_22587
T8 8433-8439 Chemical denotes oxygen http://purl.obolibrary.org/obo/CHEBI_25805
T9 10438-10447 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T10 10448-10457 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T11 10640-10649 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T12 10650-10659 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409
T13 10771-10775 Chemical denotes drug http://purl.obolibrary.org/obo/CHEBI_23888
T14 12829-12831 Chemical denotes WA http://purl.obolibrary.org/obo/CHEBI_73710
T15 12983-12994 Chemical denotes application http://purl.obolibrary.org/obo/CHEBI_33232
T16 13312-13314 Chemical denotes MG http://purl.obolibrary.org/obo/CHEBI_73611
T17 13320-13322 Chemical denotes SY http://purl.obolibrary.org/obo/CHEBI_73652
T18 13324-13326 Chemical denotes Ko http://purl.obolibrary.org/obo/CHEBI_59348
T19 13369-13371 Chemical denotes MG http://purl.obolibrary.org/obo/CHEBI_73611
T20 13377-13379 Chemical denotes SY http://purl.obolibrary.org/obo/CHEBI_73652
T21 13381-13383 Chemical denotes Ko http://purl.obolibrary.org/obo/CHEBI_59348
T22 13405-13407 Chemical denotes JM http://purl.obolibrary.org/obo/CHEBI_31739
T23 13415-13417 Chemical denotes YS http://purl.obolibrary.org/obo/CHEBI_141457
T24 13423-13425 Chemical denotes HM http://purl.obolibrary.org/obo/CHEBI_74053
T25 13431-13433 Chemical denotes SY http://purl.obolibrary.org/obo/CHEBI_73652
T26 13439-13441 Chemical denotes MG http://purl.obolibrary.org/obo/CHEBI_73611
T27 13498-13500 Chemical denotes MG http://purl.obolibrary.org/obo/CHEBI_73611
T28 13502-13504 Chemical denotes Ko http://purl.obolibrary.org/obo/CHEBI_59348
T29 13545-13547 Chemical denotes Ko http://purl.obolibrary.org/obo/CHEBI_59348
T30 13571-13573 Chemical denotes JM http://purl.obolibrary.org/obo/CHEBI_31739
T31 13581-13583 Chemical denotes YS http://purl.obolibrary.org/obo/CHEBI_141457
T32 13589-13591 Chemical denotes HM http://purl.obolibrary.org/obo/CHEBI_74053
T33 13597-13599 Chemical denotes MG http://purl.obolibrary.org/obo/CHEBI_73611
T34 13605-13607 Chemical denotes SY http://purl.obolibrary.org/obo/CHEBI_73652
T35 15073-15075 Chemical denotes ND http://purl.obolibrary.org/obo/CHEBI_73419
T36 15312-15349 Chemical denotes non-steroidal anti-inflammatory agent http://purl.obolibrary.org/obo/CHEBI_35475
T37 15326-15349 Chemical denotes anti-inflammatory agent http://purl.obolibrary.org/obo/CHEBI_67079
T38 15534-15543 Chemical denotes Lopinavir http://purl.obolibrary.org/obo/CHEBI_31781
T39 15544-15553 Chemical denotes ritonavir http://purl.obolibrary.org/obo/CHEBI_45409

LitCovid-PD-GO-BP

Id Subject Object Predicate Lexical cue
T1 1492-1500 http://purl.obolibrary.org/obo/GO_0007610 denotes behavior
T2 2096-2109 http://purl.obolibrary.org/obo/GO_0003968 denotes transcriptase
T3 2096-2109 http://purl.obolibrary.org/obo/GO_0003899 denotes transcriptase
T4 10935-10945 http://purl.obolibrary.org/obo/GO_0046903 denotes secretions

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T1 0-74 Sentence denotes Viral Load Kinetics of SARS-CoV-2 Infection in First Two Patients in Korea
T2 76-84 Sentence denotes Abstract
T3 85-260 Sentence denotes As of February 2020, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak started in China in December 2019 has been spreading in many countries in the world.
T4 261-409 Sentence denotes With the numbers of confirmed cases are increasing, information on the epidemiologic investigation and clinical manifestation have been accumulated.
T5 410-478 Sentence denotes However, data on viral load kinetics in confirmed cases are lacking.
T6 479-644 Sentence denotes Here, we present the viral load kinetics of the first two confirmed patients with mild to moderate illnesses in Korea in whom distinct viral load kinetics are shown.
T7 645-801 Sentence denotes This report suggests that viral load kinetics of SARS-CoV-2 may be different from that of previously reported other coronavirus infections such as SARS-CoV.
T8 803-1156 Sentence denotes As of February 2020, the novel coronavirus disease (COVID-19) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) started in China in December 2019 has been spreading in many countries over the world.123 The numbers of confirmed cases are increasing over 70,000 including 31 Korean patients as of third week of February 2020.
T9 1157-1473 Sentence denotes The World Health Organization declared the SARS-CoV-2 outbreak a public health emergency of international concern on January 30, 2020.4 While the information on epidemiologic investigation and clinical manifestation are being accumulated, viral kinetics of the novel virus have not been systematically evaluated yet.
T10 1474-1599 Sentence denotes To understand the behavior of the virus in human body, we present the viral load kinetics of the first two patients in Korea.
T11 1600-1847 Sentence denotes Upper respiratory tract (URT) and lower respiratory specimen (LRT) specimens were collected from confirmed patients every day after the diagnosis of SARS-CoV-2 infection and sent to Korea Center for Disease Control for follow-up tests and culture.
T12 1848-2077 Sentence denotes Nasopharyngeal and oropharyngeal swabs were collected and placed in the same tube as URT specimen, and sputum was used as LRT specimen.5 Serum, plasma, urine, and stool samples were also collected sequentially during the illness.
T13 2078-2300 Sentence denotes Real-time reverse transcriptase polymerase chain reaction (rRT-PCR) was used to detect SARS-CoV-2 using the published sequences.6 The cycle threshold (Ct) values of rRT-PCR was converted into RNA copy number of SARS-CoV-2.
T14 2301-2370 Sentence denotes The detection limit of quantitative PCR reaction was 2,690 copies/mL.
T15 2371-2487 Sentence denotes Detailed methods and values for the tests are presented in the Supplementary Data 1 and Supplementary Tables 1 to 3.
T16 2488-2594 Sentence denotes A 35-year-old Chinese woman from Wuhan, China was confirmed to be first SARS-CoV-2 infected case in Korea.
T17 2595-2813 Sentence denotes The detailed exposure history and a clinical course of this patient is described in previous report.7 Viral load kinetics of Patient 1 is shown in Fig. 1A (viral RNA copies) and Supplementary Fig. 1 (reverse Ct value).
T18 2814-2924 Sentence denotes Briefly, she was quarantined at the airport due to fever (38.3°C) at the entry inspection on January 19, 2020.
T19 2925-3083 Sentence denotes She had no significant exposure history and developed fever, chills, and myalgia one day before the entry to Korea (January 18, 2020, day 1 of symptom onset).
T20 3084-3152 Sentence denotes The virus was detected from URT specimens on day 2 of symptom onset.
T21 3153-3310 Sentence denotes As she did not have significant respiratory symptoms, LRT specimen (spontaneous sputum) was obtained with airway clearance techniques of percussion on day 3.
T22 3311-3436 Sentence denotes Although any infiltration was not noticed on her chest X-ray (CXR) on the same day, LRT specimen was positive for SARS-CoV-2.
T23 3437-3708 Sentence denotes On day 4, high resolution computed tomography (HRCT) was taken and multiple ground-glass opacities were observed in both sub-pleural spaces.7 On day 5, the viral load was increased from day 3 in LRT specimen and she required oxygen supplement via nasal cannula (3 L/min).
T24 3709-3805 Sentence denotes She eventually developed cough on day 7, and infiltration was observed on CXR from the next day.
T25 3806-4023 Sentence denotes However, it appeared that the viral loads already started to decrease from around day 7 in both URT and LRT specimens. rRT-PCR continued to be positive at low level until day 13 (LRT specimens) and 14 (URT specimens).
T26 4024-4176 Sentence denotes On day 12, her CXR was worsened with increase in oxygen requirement up to 10 L/min, while the viral loads dropped significantly from the initial values.
T27 4177-4338 Sentence denotes Therefore, by the time when the significant infiltration was visible on a plain chest radiography, the viral load might be already on its lower end of detection.
T28 4339-4460 Sentence denotes From day 14 (LRT specimen) and day 15 (URT specimen), rRT-PCR became undetectable for two consecutive days, respectively.
T29 4461-4507 Sentence denotes She had mild loose stool from day 4 to day 19.
T30 4508-4675 Sentence denotes Although RdRp and/or E gene were detected occasionally from urine and stool specimens collected from day 5 to 12, none of specimen satisfied conditions for positivity.
T31 4676-4815 Sentence denotes Only one serum sample collected on day 8 showed positive rRT-PCR result, but the Ct value was adjacent to the cut-off value for positivity.
T32 4816-4971 Sentence denotes Her symptoms, oxygen requirement, and CXR findings significantly improved from day 17 and she was discharged on day 20 of symptom onset (February 6, 2019).
T33 4972-5100 Sentence denotes Patient 2 was a 55-year-old Korean man, who had been working at Wuhan, China, arrived in Korea via Shanghai on January 22, 2020.
T34 5101-5206 Sentence denotes The detailed exposure history and a clinical course of this patient is described in Supplementary Data 1.
T35 5207-5394 Sentence denotes Briefly, he did not have any significant exposure history and developed sore throat and intermittent myalgia since January 10 which was controlled by nonsteroidal anti-inflammatory agent.
T36 5395-5508 Sentence denotes He was tested on January 23, 2020, confirmed with SARS-CoV-2 infection next day and hospitalized on the same day.
T37 5509-5600 Sentence denotes Therefore, his admission day (January 24) was considered to be the day 15 of symptom onset.
T38 5601-5726 Sentence denotes His CXR on day 15 showed infiltration and chest HRCT on day 16 showed bilateral ground-glass opacity (Supplementary Fig. 3A).
T39 5727-5835 Sentence denotes The viral load kinetics are shown in Fig. 1B (viral RNA copies) and Supplementary Fig. 2 (reverse Ct value).
T40 5836-5969 Sentence denotes In this patient, the initial test was performed on day 14 of symptom onset and SARS-CoV-2 was detected in both URT and LRT specimens.
T41 5970-6226 Sentence denotes However, the initial viral loads were relatively lower (49,047 copies/mL for URT and 391,243 copies/mL for LRT) than those of Patient 1 (46,971,053 copies/mL for URT and 9,171,220 copies/mL for LRT) in whom the test was performed on day 2 of symptom onset.
T42 6227-6337 Sentence denotes SARS-CoV-2 was detected a few more times during hospitalization from both URT and LRT specimens at low levels.
T43 6338-6436 Sentence denotes As he had just mild cough with little or no sputum, LRT specimens were available only a few times.
T44 6437-6552 Sentence denotes From D18 (URT specimen) and D20 (LRT specimen), rRT-PCR became undetectable for two consecutive days, respectively.
T45 6553-6736 Sentence denotes On day 25, RdRp (Ct value of 36.69) and E (Ct value of 33.18) genes was detected again from the URT sample of day 25, it was interpreted as negative due to high Ct value of RdRp gene.
T46 6737-6863 Sentence denotes From his plasma and stool specimens, only E genes were once detected on day 17 and it was also interpreted as negative result.
T47 6864-6944 Sentence denotes His CXR improved from day 19 and he was discharged on day 27 (February 5, 2020).
T48 6945-7081 Sentence denotes This study presents the viral load kinetics of the first two confirmed patients in Korea in whom distinct viral load kinetics are shown.
T49 7082-7330 Sentence denotes Although the viral load and CXR findings in these two patients may not represent the whole spectrum of SARS-CoV-2 illness, our report will provide many important findings and opportunity to understand this newly discovered virus infection in human.
T50 7331-7504 Sentence denotes In Patient 1, we observed one example of moderate disease (shortness of breath and oxygen requirement up to 10 L/min) with corresponding radiograph findings and viral loads.
T51 7505-7637 Sentence denotes We could observe her clinical presentation from day 2 of symptom onset and the whole clinical picture was captured with viral loads.
T52 7638-7701 Sentence denotes There are several important implications from this observation.
T53 7702-7962 Sentence denotes First, unlike SARS-CoV infection,8 we found that viral load was highest during the early phase of the illness (3–5 days from first symptom onset, fever and myalgia were the only symptoms in Patient 1) and continued to decrease until the end of the second week.
T54 7963-8147 Sentence denotes While she developed cough as well as shortness of breath and infiltration appeared on CXR at the end of first week of illness, the viral load already started to decrease at this phase.
T55 8148-8305 Sentence denotes This may have a very important implication to determine the optimal time point for antiviral treatment intervention to prevent progression to severe disease.
T56 8306-8484 Sentence denotes Second, the virus was detected from LRT specimens even before the development of LRT symptoms (cough, shortness of breath, and oxygen requirement) or visible infiltration on CXR.
T57 8485-8691 Sentence denotes This may suggest that although the patient does not complain of any LRT symptoms, the virus is already there and causing insidious pathology, ultimately leading to LRT symptoms and chest infiltration later.
T58 8692-8815 Sentence denotes However, the viral load starts to decrease in both URT and LRT specimens at the same time, which may puzzle the clinicians.
T59 8816-8956 Sentence denotes Third, unlike in MERS-CoV revealing higher concentration of virus in LRT specimens,9 viral loads were similar in both URT and LRT specimens.
T60 8957-9134 Sentence denotes Fourth, low concentration of genetic materials, especially E gene, was detected in urine and stool from the end of the first week until the patient recovered from the infection.
T61 9135-9212 Sentence denotes However, rRT-PCR results did not meet the criteria for SARS-CoV-2 positivity.
T62 9213-9311 Sentence denotes Further studies need to be performed in non-respiratory specimens such as urine and stool samples.
T63 9312-9421 Sentence denotes In Patient 2, we observed one example of mild disease with corresponding radiograph findings and viral loads.
T64 9422-9533 Sentence denotes This may represent many real-world mild cases who may present to medical facility late in their disease course.
T65 9534-9609 Sentence denotes Therefore, this patient's information has also some important implications.
T66 9610-9740 Sentence denotes First, even in a patient with mild disease (sore throat only), visible infiltration on CXR was observed at the end of second week.
T67 9741-9935 Sentence denotes Second, even in a patient with mild disease, if visible infiltration on CXR is observed, virus is still detected in both URT and LRT specimens even at the end of second week after symptom onset.
T68 9936-10073 Sentence denotes Viral loads of URT were similar with and sometimes higher than LRT specimens, and virus was detectable for longer period in URT specimen.
T69 10074-10222 Sentence denotes This could be also probably because the patient did not have significant cough and had little amount of spontaneous sputum insufficient for testing.
T70 10223-10264 Sentence denotes There are also limitations in our report.
T71 10265-10429 Sentence denotes Since we only presented two patients (mild and moderate), the information from these patients may not be generalizable to many other cases, especially severe cases.
T72 10430-10606 Sentence denotes Second, Lopinavir/ritonavir was used in both patients on day 5 and day 17 from symptom onset, but its role cannot be determined in viral load reduction or clinical improvement.
T73 10607-10788 Sentence denotes In addition, since they received Lopinavir/ritonavir which can also cause diarrhea, how much of gastrointestinal tract symptom was in fact related to SARS-CoV-2 or drug side effect.
T74 10789-10946 Sentence denotes Third, we cannot estimate the time point when these patients were exposed to virus and when they started to shed the virus from their respiratory secretions.
T75 10947-11076 Sentence denotes These data are also urgently needed to understand this virus better and to implement the control strategies as early as possible.
T76 11077-11182 Sentence denotes Finally, the virus has not been readily cultured from these specimens, yet, although we are still trying.
T77 11183-11338 Sentence denotes It is not clear whether there was not viable virus (possibly infectious) or we were not successful to culture this newly discovered virus in the beginning.
T78 11339-11440 Sentence denotes Therefore, knowing the virus load that can give a positive culture result is important in the future.
T79 11441-11547 Sentence denotes There is scarce information on viral load kinetics in SARS-CoV-2 infected patients throughout the illness.
T80 11548-11701 Sentence denotes Therefore, although our report is based on observation from only two patients, this will provide valuable insight to understand the nature of this virus.
T81 11702-11841 Sentence denotes In conclusion, we report a unique pattern of SARS-CoV-2 viral kinetics in URT and LRT specimens from first two patients diagnosed in Korea.
T82 11842-11972 Sentence denotes While two cases were different in disease course, these data will provide valuable insight to understand the nature of this virus.
T83 11974-11990 Sentence denotes Ethics statement
T84 11991-12066 Sentence denotes The clinical data and images are presented under agreement of the patients.
T85 12068-12083 Sentence denotes ACKNOWLEDGMENTS
T86 12084-12274 Sentence denotes We greatly appreciate the efforts of all the hospital employees and their families at the Incheon Medical Center and National Medical Center, who are working tirelessly during this outbreak.
T87 12275-12420 Sentence denotes We thank to Yoonju Oh, Sung Hee Kim, Yoon Soog Kang, and Kwang Sil Kim (Incheon Medical Center) for collecting and preserving clinical specimens.
T88 12421-12558 Sentence denotes We thank Hyun Mee Park (Department of Radiology, National Medical Center) for the obtainment of excellent radiologic study result safely.
T89 12559-12703 Sentence denotes We also thank to Yunyoung Jang, and Eunhee Kim for the dedication to protect healthcare workers of National Medical Center by infection control.
T90 12704-12838 Sentence denotes We sincerely appreciate the discussion and critical feedback from Dr. Janet A Englund (Seattle Children’s Hospital, Seattle, WA, USA).
T91 12839-13132 Sentence denotes Lastly, we thank all the members of the Korean Society of Infectious Diseases (KSID), the groups of Korean Emerging Infectious Diseases (KoEID) application, and Korea National Clinical Management Network (KNCMN) for COVID-19, who are coping with the current global outbreak situation together.
T92 13133-13144 Sentence denotes Disclosure:
T93 13145-13209 Sentence denotes The authors have no potential conflicts of interest to disclose.
T94 13210-13231 Sentence denotes Author Contributions:
T95 13232-13250 Sentence denotes Conceptualization:
T96 13251-13275 Sentence denotes Kim JY, Chin BS, Kim YJ.
T97 13276-13290 Sentence denotes Data curation:
T98 13291-13330 Sentence denotes Kim JY, Chin BS, Han MG, Kim SY, Ko JH.
T99 13331-13347 Sentence denotes Formal analysis:
T100 13348-13387 Sentence denotes Kim JY, Chin BS, Han MG, Kim SY, Ko JH.
T101 13388-13400 Sentence denotes Methodology:
T102 13401-13442 Sentence denotes Kim JM, Chung YS, Kim HM, Kim SY, Han MG.
T103 13443-13468 Sentence denotes Writing - original draft:
T104 13469-13508 Sentence denotes Kim YJ, Kim JY, Chin BS, Han MG, Ko JH.
T105 13509-13536 Sentence denotes Writing - review & editing:
T106 13537-13617 Sentence denotes Kim JY, Ko JH, Kim Y, Kim YJ, Kim JM, Chung YS, Kim HM, Han MG, Kim SY, Chin BS.
T107 13619-13642 Sentence denotes SUPPLEMENTARY MATERIALS
T108 13643-13663 Sentence denotes Supplementary Data 1
T109 13664-13727 Sentence denotes Laboratory procedures and detailed clinical course of Patient 2
T110 13728-13749 Sentence denotes Supplementary Table 1
T111 13750-13839 Sentence denotes Clinical course and viral loads of Patient 1 according to the timeline from symptom onset
T112 13840-13861 Sentence denotes Supplementary Table 2
T113 13862-13951 Sentence denotes Clinical course and viral loads of Patient 2 according to the timeline from symptom onset
T114 13952-13973 Sentence denotes Supplementary Table 3
T115 13974-14029 Sentence denotes Estimated number of viral copy of respiratory specimens
T116 14030-14050 Sentence denotes Supplementary Fig. 1
T117 14051-14293 Sentence denotes Viral load kinetics according to the clinical course of Patient 1, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.
T118 14294-14314 Sentence denotes Supplementary Fig. 2
T119 14315-14557 Sentence denotes Viral load kinetics according to the clinical course of Patient 2, presented by reverse Ct value. (A) Viral load kinetics of respiratory specimen, (B) Viral load kinetics of blood specimen, (C) Viral load kinetics of urine and stool specimen.
T120 14558-14578 Sentence denotes Supplementary Fig. 3
T121 14579-14776 Sentence denotes Images of Patient 2. (A) Chest X-ray taken on admission, January 24, 2010 (day 15 from symptom onset). (B) High resolution computed tomography taken on January 25, 2010 (day 16 from symptom onset).
T122 14778-15010 Sentence denotes Fig. 1 Viral load kinetics according to the clinical course of the first two SARS-CoV-2 infected patients in Korea. (A) Viral load kinetics and clinical course of Patient 1. (B) Viral load kinetics and clinical course of Patient 2.
T123 15011-15226 Sentence denotes URT = upper respiratory tract, LRT = lower respiratory tract, ND = not detected, CXR = chest X-ray, GGO = ground glass opacity, CT = computed tomography, SARS-CoV-2 = severe acute respiratory syndrome coronavirus 2.
T124 15227-15412 Sentence denotes a)In Patient 2, the exact fever duration could not be estimated because he had taken non-steroidal anti-inflammatory agent to control his myalgia and sore throat before hospitalization.
T125 15413-15554 Sentence denotes When his physician discontinued the medication, the fever was observed; b)Patient 2 experienced loose stool after taking Lopinavir/ritonavir.

LitCovid-PD-HP

Id Subject Object Predicate Lexical cue hp_id
T1 2865-2870 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T2 2979-2984 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T3 2986-2992 Phenotype denotes chills http://purl.obolibrary.org/obo/HP_0025143
T4 2998-3005 Phenotype denotes myalgia http://purl.obolibrary.org/obo/HP_0003326
T5 3734-3739 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T6 5279-5290 Phenotype denotes sore throat http://purl.obolibrary.org/obo/HP_0033050
T7 5308-5315 Phenotype denotes myalgia http://purl.obolibrary.org/obo/HP_0003326
T8 6358-6363 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T9 7390-7409 Phenotype denotes shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T10 7848-7853 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T11 7858-7865 Phenotype denotes myalgia http://purl.obolibrary.org/obo/HP_0003326
T12 7983-7988 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T13 8000-8019 Phenotype denotes shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T14 8401-8406 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T15 8408-8427 Phenotype denotes shortness of breath http://purl.obolibrary.org/obo/HP_0002098
T16 9654-9665 Phenotype denotes sore throat http://purl.obolibrary.org/obo/HP_0033050
T17 10147-10152 Phenotype denotes cough http://purl.obolibrary.org/obo/HP_0012735
T18 10681-10689 Phenotype denotes diarrhea http://purl.obolibrary.org/obo/HP_0002014
T19 15253-15258 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945
T20 15365-15372 Phenotype denotes myalgia http://purl.obolibrary.org/obo/HP_0003326
T21 15377-15388 Phenotype denotes sore throat http://purl.obolibrary.org/obo/HP_0033050
T22 15465-15470 Phenotype denotes fever http://purl.obolibrary.org/obo/HP_0001945