PMC:7033720 / 7254-9688
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
90 | 1998-2001 | Gene | denotes | AST | Gene:26503 |
91 | 2105-2109 | Chemical | denotes | UREA | MESH:D014508 |
98 | 2226-2229 | Gene | denotes | AST | Gene:26503 |
99 | 2290-2300 | Chemical | denotes | creatinine | MESH:D003404 |
100 | 2329-2339 | Chemical | denotes | creatinine | MESH:D003404 |
101 | 2341-2345 | Chemical | denotes | UREA | MESH:D014508 |
102 | 2348-2352 | Chemical | denotes | Urea | MESH:D014508 |
103 | 2353-2361 | Chemical | denotes | nitrogen | MESH:D009584 |
128 | 351-355 | Gene | denotes | a 21 | Gene:28922 |
129 | 71-79 | Species | denotes | patients | Tax:9606 |
130 | 124-131 | Species | denotes | Patient | Tax:9606 |
131 | 337-344 | Species | denotes | Patient | Tax:9606 |
132 | 601-611 | Species | denotes | outpatient | Tax:9606 |
133 | 744-752 | Species | denotes | patients | Tax:9606 |
134 | 1031-1038 | Species | denotes | patient | Tax:9606 |
135 | 1320-1327 | Species | denotes | patient | Tax:9606 |
136 | 1416-1424 | Species | denotes | patients | Tax:9606 |
137 | 1548-1555 | Species | denotes | patient | Tax:9606 |
138 | 1562-1569 | Species | denotes | patient | Tax:9606 |
139 | 1126-1130 | Chemical | denotes | SpO2 | |
140 | 1139-1145 | Chemical | denotes | oxygen | MESH:D010100 |
141 | 61-70 | Disease | denotes | pneumonia | MESH:D011014 |
142 | 204-209 | Disease | denotes | fever | MESH:D005334 |
143 | 240-245 | Disease | denotes | cough | MESH:D003371 |
144 | 402-415 | Disease | denotes | febrile cough | MESH:D003371 |
145 | 425-430 | Disease | denotes | fever | MESH:D005334 |
146 | 860-876 | Disease | denotes | viral infections | MESH:D001102 |
147 | 954-963 | Disease | denotes | infection | MESH:D007239 |
148 | 1097-1116 | Disease | denotes | shortness of breath | MESH:D004417 |
149 | 1190-1206 | Disease | denotes | pleural effusion | MESH:D010996 |
150 | 1346-1372 | Disease | denotes | Type I respiratory failure | MESH:D012131 |
151 | 1451-1470 | Disease | denotes | Infectious Diseases | MESH:D003141 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T42 | 264-270 | Body_part | denotes | sputum | http://purl.org/sig/ont/fma/fma312401 |
T43 | 462-468 | Body_part | denotes | sputum | http://purl.org/sig/ont/fma/fma312401 |
T44 | 722-727 | Body_part | denotes | Chest | http://purl.org/sig/ont/fma/fma9576 |
T45 | 797-803 | Body_part | denotes | pleura | http://purl.org/sig/ont/fma/fma9583 |
T46 | 821-825 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T47 | 895-900 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
T48 | 1082-1088 | Body_part | denotes | mental | http://purl.org/sig/ont/fma/fma264279 |
T49 | 1214-1223 | Body_part | denotes | left lung | http://purl.org/sig/ont/fma/fma7310 |
T50 | 1831-1842 | Body_part | denotes | Neutrophils | http://purl.org/sig/ont/fma/fma62860 |
T51 | 1871-1883 | Body_part | denotes | T lymphocyte | http://purl.org/sig/ont/fma/fma62870 |
T52 | 1938-1946 | Body_part | denotes | Platelet | http://purl.org/sig/ont/fma/fma62851 |
T53 | 2200-2207 | Body_part | denotes | alanine | http://purl.org/sig/ont/fma/fma82749 |
T54 | 2368-2379 | Body_part | denotes | haemoglobin | http://purl.org/sig/ont/fma/fma62293 |
T55 | 2422-2427 | Body_part | denotes | blood | http://purl.org/sig/ont/fma/fma9670 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T3 | 264-270 | Body_part | denotes | sputum | http://purl.obolibrary.org/obo/UBERON_0007311 |
T4 | 462-468 | Body_part | denotes | sputum | http://purl.obolibrary.org/obo/UBERON_0007311 |
T5 | 722-727 | Body_part | denotes | Chest | http://purl.obolibrary.org/obo/UBERON_0001443 |
T6 | 797-803 | Body_part | denotes | pleura | http://purl.obolibrary.org/obo/UBERON_0000977 |
T7 | 821-831 | Body_part | denotes | lung field | http://purl.obolibrary.org/obo/UBERON_0022361 |
T8 | 821-825 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T9 | 1190-1206 | Body_part | denotes | pleural effusion | http://purl.obolibrary.org/obo/UBERON_0000175 |
T10 | 1214-1223 | Body_part | denotes | left lung | http://purl.obolibrary.org/obo/UBERON_0002168 |
T11 | 1219-1223 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T12 | 1286-1295 | Body_part | denotes | extension | http://purl.obolibrary.org/obo/UBERON_2000106 |
T13 | 2422-2427 | Body_part | denotes | blood | http://purl.obolibrary.org/obo/UBERON_0000178 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T9 | 61-70 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T10 | 860-876 | Disease | denotes | viral infections | http://purl.obolibrary.org/obo/MONDO_0005108 |
T11 | 954-963 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T12 | 1353-1372 | Disease | denotes | respiratory failure | http://purl.obolibrary.org/obo/MONDO_0021113 |
T13 | 1451-1461 | Disease | denotes | Infectious | http://purl.obolibrary.org/obo/MONDO_0005550 |
T14 | 2039-2041 | Disease | denotes | CK | http://purl.obolibrary.org/obo/MONDO_0017941 |
T15 | 2058-2060 | Disease | denotes | CK | http://purl.obolibrary.org/obo/MONDO_0017941 |
T16 | 2260-2262 | Disease | denotes | CK | http://purl.obolibrary.org/obo/MONDO_0017941 |
T17 | 2282-2284 | Disease | denotes | CK | http://purl.obolibrary.org/obo/MONDO_0017941 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T52 | 138-139 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T53 | 152-156 | http://purl.obolibrary.org/obo/UBERON_0003101 | denotes | male |
T54 | 152-156 | http://www.ebi.ac.uk/efo/EFO_0000970 | denotes | male |
T55 | 351-355 | http://purl.obolibrary.org/obo/CLO_0053711 | denotes | a 21 |
T56 | 365-371 | http://purl.obolibrary.org/obo/UBERON_0003100 | denotes | female |
T57 | 482-483 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T58 | 658-662 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T59 | 722-727 | http://www.ebi.ac.uk/efo/EFO_0000965 | denotes | Chest |
T60 | 797-803 | http://purl.obolibrary.org/obo/UBERON_0000977 | denotes | pleura |
T61 | 821-825 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T62 | 821-825 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T63 | 826-831 | http://purl.obolibrary.org/obo/UBERON_0007688 | denotes | field |
T64 | 840-842 | http://purl.obolibrary.org/obo/CLO_0050050 | denotes | S1 |
T65 | 895-900 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
T66 | 1158-1159 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T67 | 1190-1206 | http://purl.obolibrary.org/obo/UBERON_0000175 | denotes | pleural effusion |
T68 | 1214-1223 | http://purl.obolibrary.org/obo/UBERON_0002168 | denotes | left lung |
T69 | 1714-1718 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T70 | 1796-1800 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | test |
T71 | 1910-1912 | http://purl.obolibrary.org/obo/CLO_0003622 | denotes | Hb |
T72 | 2015-2017 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
T73 | 2036-2038 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
T74 | 2047-2049 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
T75 | 2050-2052 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
T76 | 2061-2063 | http://purl.obolibrary.org/obo/PR_000010213 | denotes | MB |
T77 | 2069-2071 | http://purl.obolibrary.org/obo/CLO_0053733 | denotes | 11 |
T78 | 2285-2287 | http://purl.obolibrary.org/obo/PR_000010213 | denotes | MB |
T79 | 2308-2310 | http://purl.obolibrary.org/obo/PR_000010213 | denotes | MB |
T80 | 2363-2365 | http://purl.obolibrary.org/obo/CLO_0003622 | denotes | Hb |
T81 | 2422-2427 | http://purl.obolibrary.org/obo/UBERON_0000178 | denotes | blood |
T82 | 2422-2427 | http://www.ebi.ac.uk/efo/EFO_0000296 | denotes | blood |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T15 | 152-156 | Chemical | denotes | male | http://purl.obolibrary.org/obo/CHEBI_30780 |
T16 | 1139-1145 | Chemical | denotes | oxygen | http://purl.obolibrary.org/obo/CHEBI_25805 |
T17 | 1998-2001 | Chemical | denotes | AST | http://purl.obolibrary.org/obo/CHEBI_76649 |
T18 | 2105-2109 | Chemical | denotes | UREA | http://purl.obolibrary.org/obo/CHEBI_16199 |
T19 | 2200-2207 | Chemical | denotes | alanine | http://purl.obolibrary.org/obo/CHEBI_16449 |
T20 | 2226-2229 | Chemical | denotes | AST | http://purl.obolibrary.org/obo/CHEBI_76649 |
T21 | 2232-2241 | Chemical | denotes | aspartate | http://purl.obolibrary.org/obo/CHEBI_132943|http://purl.obolibrary.org/obo/CHEBI_29995|http://purl.obolibrary.org/obo/CHEBI_72314 |
T24 | 2265-2273 | Chemical | denotes | creatine | http://purl.obolibrary.org/obo/CHEBI_16919|http://purl.obolibrary.org/obo/CHEBI_57947 |
T26 | 2290-2300 | Chemical | denotes | creatinine | http://purl.obolibrary.org/obo/CHEBI_16737 |
T27 | 2329-2339 | Chemical | denotes | creatinine | http://purl.obolibrary.org/obo/CHEBI_16737 |
T28 | 2341-2345 | Chemical | denotes | UREA | http://purl.obolibrary.org/obo/CHEBI_16199 |
T29 | 2348-2352 | Chemical | denotes | Urea | http://purl.obolibrary.org/obo/CHEBI_16199 |
T30 | 2353-2361 | Chemical | denotes | nitrogen | http://purl.obolibrary.org/obo/CHEBI_25555 |
T31 | 2368-2379 | Chemical | denotes | haemoglobin | http://purl.obolibrary.org/obo/CHEBI_35143 |
T32 | 2387-2394 | Chemical | denotes | lactate | http://purl.obolibrary.org/obo/CHEBI_24996 |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T7 | 61-70 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T8 | 204-209 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
T9 | 240-245 | Phenotype | denotes | cough | http://purl.obolibrary.org/obo/HP_0012735 |
T10 | 410-415 | Phenotype | denotes | cough | http://purl.obolibrary.org/obo/HP_0012735 |
T11 | 417-423 | Phenotype | denotes | chills | http://purl.obolibrary.org/obo/HP_0025143 |
T12 | 425-430 | Phenotype | denotes | fever | http://purl.obolibrary.org/obo/HP_0001945 |
T13 | 767-786 | Phenotype | denotes | pulmonary opacities | http://purl.obolibrary.org/obo/HP_0031457 |
T14 | 1097-1116 | Phenotype | denotes | shortness of breath | http://purl.obolibrary.org/obo/HP_0002098 |
T15 | 1190-1206 | Phenotype | denotes | pleural effusion | http://purl.obolibrary.org/obo/HP_0002202 |
T16 | 1353-1372 | Phenotype | denotes | respiratory failure | http://purl.obolibrary.org/obo/HP_0002878 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T2 | 860-876 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infections |
T3 | 2058-2063 | http://purl.obolibrary.org/obo/GO_0004111 | denotes | CK-MB |
T4 | 2282-2287 | http://purl.obolibrary.org/obo/GO_0004111 | denotes | CK-MB |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T66 | 0-123 | Sentence | denotes | On 2nd January 2020, samples were collected from two unusual pneumonia patients from Zhongnan Hospital of Wuhan University. |
T67 | 124-336 | Sentence | denotes | Patient 1 was a 39-year-old male staff at Huanan Seafood Market who experienced fever (up to 37.7°C) and aggravated cough with frothy white sputum for 5 days before admitted to the hospital on 25th December 2019. |
T68 | 337-547 | Sentence | denotes | Patient 2 was a 21-year-old female who developed an intermittent febrile cough, chills, fever (up to 40°C), and frothy white sputum after having a contact with Huanan Seafood Market staff on 22nd December 2019. |
T69 | 548-622 | Sentence | denotes | She was admitted on 28th December after unsuccessful outpatient treatment. |
T70 | 623-721 | Sentence | denotes | The results of clinical laboratory test on the first day of hospitalization are listed in Table 1. |
T71 | 722-901 | Sentence | denotes | Chest CT scan of both patients showed patchy pulmonary opacities below the pleura in the bilateral lung field (Figure S1), which suggests viral infections may occur in both lungs. |
T72 | 902-1007 | Sentence | denotes | However, the subsequent routine anti-viral and anti-infection treatment did not alleviate their symptoms. |
T73 | 1008-1157 | Sentence | denotes | On 31st December 2019, patient 1 had more severe symptoms, including poor mental states, shortness of breath, and 86% SpO2 without oxygen inhalation. |
T74 | 1158-1315 | Sentence | denotes | A CT re-examination showed mild pleural effusion in the left lung, an increase in the density of ground-glass opacities, and an extension of the patchy area. |
T75 | 1316-1389 | Sentence | denotes | The patient later experienced Type I respiratory failure on the same day. |
T76 | 1390-1505 | Sentence | denotes | On 2nd January 2020, both patients were transferred to Wuhan Infectious Diseases Hospital for continuing treatment. |
T77 | 1506-1684 | Sentence | denotes | To the date this manuscript was prepared, patient 1 and patient 2 were later discharged from the hospital in stable condition on 12th January and 11th January 2020, respectively. |
T78 | 1685-1693 | Sentence | denotes | Table 1. |
T79 | 1694-1755 | Sentence | denotes | Clinical laboratory test on the first day of hospitalization. |
T80 | 1756-1800 | Sentence | denotes | Items Case 1 Case 2 Normal range of lab test |
T81 | 1801-1830 | Sentence | denotes | WBC, ×109/L 5.23 2.89 3.5–9.5 |
T82 | 1831-1870 | Sentence | denotes | Neutrophils, ×109/L/L 3.58 1.92 1.8–6.3 |
T83 | 1871-1909 | Sentence | denotes | T lymphocyte, ×109/L 1.32 0.46 1.1–3.2 |
T84 | 1910-1937 | Sentence | denotes | Hb, g/L 138.6 127.5 115–150 |
T85 | 1938-1970 | Sentence | denotes | Platelet, ×109/L 170 117 125–350 |
T86 | 1971-1997 | Sentence | denotes | Albumin, g/L 65.9 47 40–55 |
T87 | 1998-2017 | Sentence | denotes | AST, U/L 92 33 7–45 |
T88 | 2018-2038 | Sentence | denotes | ALT, U/L 30 30 13–45 |
T89 | 2039-2057 | Sentence | denotes | CK, U/L 36 35 <171 |
T90 | 2058-2079 | Sentence | denotes | CK-MB, U/L 11 10 0–25 |
T91 | 2080-2104 | Sentence | denotes | LDH, U/L 313 247 110–245 |
T92 | 2105-2135 | Sentence | denotes | UREA, mmol/L 2.81 2.7 2.8–7.60 |
T93 | 2136-2164 | Sentence | denotes | CREA, μmol/L 73.9 57.2 49–90 |
T94 | 2165-2434 | Sentence | denotes | Definition of abbreviations: ALT = alanine aminotransferase; AST = aspartate aminotransferase; CK = creatine kinase; CK-MB = creatinine kinase–MB isoenzyme; CREA = creatinine; UREA = Urea nitrogen; Hb = haemoglobin; LDH = lactate dehydrogenase; WBC = white blood count. |