PMC:7033720 / 13140-16434
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
234 | 2012-2018 | Species | denotes | b A 15 | Tax:447219 |
235 | 2221-2227 | Species | denotes | b A 20 | Tax:447224 |
236 | 1083-1088 | CellLine | denotes | WHU01 | CVCL:9726 |
237 | 1145-1150 | CellLine | denotes | WHU01 | CVCL:9726 |
238 | 1211-1216 | CellLine | denotes | WHU01 | CVCL:9726 |
239 | 1275-1280 | CellLine | denotes | WHU01 | CVCL:9726 |
240 | 1339-1344 | CellLine | denotes | WHU01 | CVCL:9726 |
241 | 1402-1407 | CellLine | denotes | WHU01 | CVCL:9726 |
242 | 1466-1471 | CellLine | denotes | WHU01 | CVCL:9726 |
243 | 1530-1535 | CellLine | denotes | WHU01 | CVCL:9726 |
244 | 1593-1598 | CellLine | denotes | WHU01 | CVCL:9726 |
245 | 1658-1663 | CellLine | denotes | WHU01 | CVCL:9726 |
246 | 1721-1726 | CellLine | denotes | WHU01 | CVCL:9726 |
247 | 1784-1789 | CellLine | denotes | WHU01 | CVCL:9726 |
248 | 1866-1871 | CellLine | denotes | WHU01 | CVCL:9726 |
249 | 1934-1939 | CellLine | denotes | WHU01 | CVCL:9726 |
250 | 2005-2010 | CellLine | denotes | WHU01 | CVCL:9726 |
251 | 2074-2079 | CellLine | denotes | WHU01 | CVCL:9726 |
252 | 2144-2149 | CellLine | denotes | WHU01 | CVCL:9726 |
253 | 2199-2219 | CellLine | denotes | 19.10 1.90E-47 WHU01 | CVCL:6820 |
254 | 2283-2288 | CellLine | denotes | WHU01 | CVCL:9726 |
255 | 2350-2355 | CellLine | denotes | WHU01 | CVCL:9726 |
256 | 2418-2423 | CellLine | denotes | WHU01 | CVCL:9726 |
257 | 2481-2486 | CellLine | denotes | WHU01 | CVCL:9726 |
259 | 938-943 | CellLine | denotes | WHU01 | CVCL:9726 |
269 | 367-375 | Species | denotes | patients | Tax:9606 |
270 | 402-405 | Species | denotes | CoV | Tax:11118 |
271 | 463-472 | Species | denotes | 2019-nCoV | Tax:2697049 |
272 | 833-844 | Species | denotes | coronaviral | Tax:11118 |
273 | 878-886 | Species | denotes | patients | Tax:9606 |
274 | 381-389 | Disease | denotes | infected | MESH:D007239 |
275 | 279-287 | CellLine | denotes | MN988668 | CVCL:U508 |
276 | 292-300 | CellLine | denotes | MN988669 | CVCL:U508 |
277 | 480-485 | CellLine | denotes | WHU01 | CVCL:9726 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T65 | 25-31 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
T66 | 107-117 | Body_part | denotes | nucleotide | http://purl.org/sig/ont/fma/fma82740 |
T67 | 204-210 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
T68 | 566-572 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
T69 | 663-669 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
T70 | 864-869 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
T71 | 903-913 | Body_part | denotes | nucleotide | http://purl.org/sig/ont/fma/fma82740 |
T72 | 954-961 | Body_part | denotes | genomes | http://purl.org/sig/ont/fma/fma84116 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T111 | 600-609 | http://www.ebi.ac.uk/efo/EFO_0000876 | denotes | extremely |
T112 | 826-832 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | active |
T113 | 864-869 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
T114 | 1098-1103 | http://purl.obolibrary.org/obo/CLO_0001012 | denotes | 221 1 |
T115 | 1110-1112 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
T116 | 1154-1155 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T117 | 1172-1173 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T118 | 1220-1221 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T119 | 1238-1239 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T120 | 1272-1274 | http://purl.obolibrary.org/obo/CLO_0050509 | denotes | 27 |
T121 | 1298-1299 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T122 | 1348-1350 | http://purl.obolibrary.org/obo/CLO_0009421 | denotes | TT |
T123 | 1348-1350 | http://purl.obolibrary.org/obo/CLO_0052184 | denotes | TT |
T124 | 1348-1350 | http://purl.obolibrary.org/obo/CLO_0052185 | denotes | TT |
T125 | 1363-1365 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | AA |
T126 | 1368-1370 | http://purl.obolibrary.org/obo/CLO_0009421 | denotes | TT |
T127 | 1368-1370 | http://purl.obolibrary.org/obo/CLO_0052184 | denotes | TT |
T128 | 1368-1370 | http://purl.obolibrary.org/obo/CLO_0052185 | denotes | TT |
T129 | 1553-1554 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T130 | 1602-1603 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T131 | 1620-1621 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T132 | 1681-1682 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T133 | 1943-1945 | http://purl.obolibrary.org/obo/CLO_0009421 | denotes | TT |
T134 | 1943-1945 | http://purl.obolibrary.org/obo/CLO_0052184 | denotes | TT |
T135 | 1943-1945 | http://purl.obolibrary.org/obo/CLO_0052185 | denotes | TT |
T136 | 1962-1964 | http://purl.obolibrary.org/obo/CLO_0001627 | denotes | AA |
T137 | 1967-1969 | http://purl.obolibrary.org/obo/CLO_0009421 | denotes | TT |
T138 | 1967-1969 | http://purl.obolibrary.org/obo/CLO_0052184 | denotes | TT |
T139 | 1967-1969 | http://purl.obolibrary.org/obo/CLO_0052185 | denotes | TT |
T140 | 2014-2015 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T141 | 2036-2037 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T142 | 2101-2102 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T143 | 2223-2224 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T144 | 2245-2246 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T145 | 2291-2292 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T146 | 2313-2314 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T147 | 2358-2359 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T148 | 2380-2384 | http://purl.obolibrary.org/obo/CLO_0001599 | denotes | A 54 |
T149 | 2424-2427 | http://purl.obolibrary.org/obo/CLO_0008954 | denotes | S C |
T150 | 2444-2445 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T151 | 2497-2498 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T152 | 2519-2520 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T153 | 2629-2630 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T154 | 2647-2648 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T155 | 2695-2696 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T156 | 2713-2714 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T157 | 2747-2749 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 41 |
T158 | 2774-2779 | http://purl.obolibrary.org/obo/CLO_0002087 | denotes | C 129 |
T159 | 2813-2814 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T160 | 2835-2836 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T161 | 2901-2902 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T162 | 3041-3042 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T163 | 3047-3050 | http://purl.obolibrary.org/obo/CLO_0001311 | denotes | 356 |
T164 | 3161-3162 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T165 | 3183-3184 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T166 | 3237-3238 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T167 | 3259-3260 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T33 | 107-117 | Chemical | denotes | nucleotide | http://purl.obolibrary.org/obo/CHEBI_36976 |
T34 | 903-913 | Chemical | denotes | nucleotide | http://purl.obolibrary.org/obo/CHEBI_36976 |
T35 | 1348-1350 | Chemical | denotes | TT | http://purl.obolibrary.org/obo/CHEBI_73665 |
T36 | 1363-1365 | Chemical | denotes | AA | http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816 |
T38 | 1368-1370 | Chemical | denotes | TT | http://purl.obolibrary.org/obo/CHEBI_73665 |
T39 | 1943-1945 | Chemical | denotes | TT | http://purl.obolibrary.org/obo/CHEBI_73665 |
T40 | 1962-1964 | Chemical | denotes | AA | http://purl.obolibrary.org/obo/CHEBI_15843|http://purl.obolibrary.org/obo/CHEBI_72816 |
T42 | 1967-1969 | Chemical | denotes | TT | http://purl.obolibrary.org/obo/CHEBI_73665 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T121 | 0-85 | Sentence | denotes | On 8th January 2020, the genome comparisons and evolutionary analyses were performed. |
T122 | 86-316 | Sentence | denotes | Although some single nucleotide polymorphism (SNP) profiles were identified in the mNGS data (Table 2), the consensus genome sequences obtained from the patient 1 and 2 were identical (GenBank MN988668 and MN988669, respectively). |
T123 | 317-424 | Sentence | denotes | These results indicated that these two individual patients were infected by the same CoV at separate times. |
T124 | 425-541 | Sentence | denotes | We named the two clinical isolates as 2019-nCoV strain WHU01 and WHU02, respectively, according to WHO announcement. |
T125 | 542-887 | Sentence | denotes | Based on the results of genome mapping, our data revealed extremely high viral abundance within the samples: the average genome coverage was 523.6X and 133.7X and the estimated abundance level were 1.5% and 0.62% of total reads sequenced for patient 1 and 2, respectively, suggesting active coronaviral replication in the lungs of both patients. |
T126 | 888-896 | Sentence | denotes | Table 2. |
T127 | 897-962 | Sentence | denotes | Minor nucleotide variant identified from WHU01 and WHU02 genomes. |
T128 | 963-1082 | Sentence | denotes | Strain Region Variant Start Poisiton End Position Length Change Coverage Polymorphism Type VariantFrequency (%) P-value |
T129 | 1083-1144 | Sentence | denotes | WHU01 1a T 221 221 1 C → T 27 SNP (transition) 14.80 6.70E-07 |
T130 | 1145-1210 | Sentence | denotes | WHU01 1a A 1103 1103 1 T → A 119 SNP (transversion) 5.00 5.40E-14 |
T131 | 1211-1274 | Sentence | denotes | WHU01 1a A 1820 1820 1 G → A 97 SNP (transition) 11.30 2.00E-27 |
T132 | 1275-1338 | Sentence | denotes | WHU01 1a G 3916 3916 1 A → G 113 SNP (transition) 5.30 3.90E-14 |
T133 | 1339-1401 | Sentence | denotes | WHU01 1a TT 3919 3920 2 AA → TT 110 Substitution 5.50 1.30E-13 |
T134 | 1402-1465 | Sentence | denotes | WHU01 1a T 3923 3923 1 C → T 108 SNP (transition) 5.60 3.00E-14 |
T135 | 1466-1529 | Sentence | denotes | WHU01 1a T 5701 5701 1 C → T 247 SNP (transition) 5.30 5.70E-29 |
T136 | 1530-1592 | Sentence | denotes | WHU01 1a G 8892 8892 1 A → G 69 SNP (transition) 5.80 5.40E-10 |
T137 | 1593-1657 | Sentence | denotes | WHU01 1a A 8895 8895 1 T → A 65 SNP (transversion) 6.20 4.20E-10 |
T138 | 1658-1720 | Sentence | denotes | WHU01 1a G 8975 8975 1 A → G 59 SNP (transition) 5.10 6.50E-08 |
T139 | 1721-1783 | Sentence | denotes | WHU01 1a C 9114 9114 1 T → C 43 SNP (transition) 7.00 7.70E-07 |
T140 | 1784-1865 | Sentence | denotes | WHU01 1a 11,081 11,081 1 (T)8 → (T)7 78 Deletion (tandem repeat) 12.80 1.20E-20 |
T141 | 1866-1933 | Sentence | denotes | WHU01 1a C 13,074 13,074 1 T → C 110 SNP (transition) 5.50 3.30E-14 |
T142 | 1934-2004 | Sentence | denotes | WHU01 1a TT 13,282 13,283 2 AA → TT 78 → 79 Substitution 5.10 9.40E-10 |
T143 | 2005-2073 | Sentence | denotes | WHU01 1b A 15,079 15,079 1 C → A 57 SNP (transversion) 8.80 1.30E-13 |
T144 | 2074-2143 | Sentence | denotes | WHU01 1b T 18,252 18,252 1 A → T 192 SNP (transversion) 6.30 5.50E-23 |
T145 | 2144-2213 | Sentence | denotes | WHU01 1b T 19,163 19,163 1 C → → T 89 SNP (transition) 19.10 1.90E-47 |
T146 | 2214-2282 | Sentence | denotes | WHU01 1b A 20,234 20,234 1 C → A 67 SNP (transversion) 6.00 1.20E-09 |
T147 | 2283-2349 | Sentence | denotes | WHU01 S A 22,315 22,315 1 G → A 182 SNP (transition) 6.60 4.70E-28 |
T148 | 2350-2417 | Sentence | denotes | WHU01 S A 22,447 22,447 1 C → A 54 SNP (transversion) 5.60 2.00E-07 |
T149 | 2418-2480 | Sentence | denotes | WHU01 S C 24,322 24,322 1 A → C 325 SNP (transversion) 38.50 0 |
T150 | 2481-2555 | Sentence | denotes | WHU01 Other ORF A 26,313 26,313 1 G → A 29 SNP (transition) 10.30 1.50E-08 |
T151 | 2556-2619 | Sentence | denotes | WHU02 1a T 1100 1100 1 C → T 390 SNP (transition) 6.70 1.50E-56 |
T152 | 2620-2685 | Sentence | denotes | WHU02 1a A 1103 1103 1 T → A 391 SNP (transversion) 5.90 3.10E-51 |
T153 | 2686-2749 | Sentence | denotes | WHU02 1a A 1820 1820 1 G → A 382 SNP (transition) 5.20 1.00E-41 |
T154 | 2750-2803 | Sentence | denotes | WHU02 1a C 6823 6822 0 +C 129 Insertion 5.40 2.50E-16 |
T155 | 2804-2873 | Sentence | denotes | WHU02 1a A 10,778 10,778 1 T → A 323 SNP (transversion) 5.30 2.40E-32 |
T156 | 2874-2943 | Sentence | denotes | WHU02 1a T 11,366 11,366 1 A → T 250 SNP (transversion) 6.00 4.40E-31 |
T157 | 2944-3013 | Sentence | denotes | WHU02 1a T 11,562 11,562 1 C → T 397 SNP (transition) 13.60 1.30E-138 |
T158 | 3014-3083 | Sentence | denotes | WHU02 1b T 13,692 13,692 1 A → T 356 SNP (transversion) 7.00 1.60E-57 |
T159 | 3084-3151 | Sentence | denotes | WHU02 1b C 14,306 14,306 1 T → C 279 SNP (transition) 7.90 9.20E-50 |
T160 | 3152-3220 | Sentence | denotes | WHU02 1b A 14,315 14,315 1 G → A 244 SNP (transition) 10.70 6.90E-57 |
T161 | 3221-3294 | Sentence | denotes | WHU02 Other ORF A 26,504 26,504 1 G → A 63 SNP (transition) 6.30 1.50E-10 |