PMC:7033706 / 5512-6146
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
135 | 302-306 | Gene | denotes | DPP4 | Gene:1803 |
136 | 47-50 | Species | denotes | CoV | Tax:11118 |
137 | 120-125 | Species | denotes | human | Tax:9606 |
138 | 126-139 | Species | denotes | coronaviruses | Tax:11118 |
139 | 151-159 | Species | denotes | SARS-CoV | Tax:694009 |
140 | 164-172 | Species | denotes | MERS-CoV | Tax:1335626 |
141 | 191-195 | Species | denotes | CoVs | Tax:11118 |
142 | 296-301 | Species | denotes | human | Tax:9606 |
143 | 307-322 | Species | denotes | transgenic mice | Tax:10090 |
144 | 577-586 | Species | denotes | 2019-nCoV | Tax:2697049 |
145 | 606-619 | Species | denotes | coronaviruses | Tax:11118 |
146 | 102-111 | Disease | denotes | infection | MESH:D007239 |
147 | 333-346 | Disease | denotes | CoV infection | MESH:D018352 |
148 | 417-436 | Disease | denotes | 2019-nCoV infection | MESH:C000657245 |
149 | 564-573 | Disease | denotes | infection | MESH:D007239 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T20 | 102-111 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T21 | 151-159 | Disease | denotes | SARS-CoV | http://purl.obolibrary.org/obo/MONDO_0005091 |
T22 | 337-346 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T23 | 417-436 | Disease | denotes | 2019-nCoV infection | http://purl.obolibrary.org/obo/MONDO_0100096 |
T24 | 427-436 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T25 | 564-573 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T77 | 41-42 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T78 | 43-46 | http://purl.obolibrary.org/obo/NCBITaxon_9596 | denotes | pan |
T79 | 73-80 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
T80 | 120-125 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T81 | 184-187 | http://purl.obolibrary.org/obo/NCBITaxon_9397 | denotes | bat |
T82 | 231-238 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
T83 | 276-283 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
T84 | 296-301 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T85 | 474-481 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
T86 | 485-486 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T38 | 58-67 | Chemical | denotes | inhibitor | http://purl.obolibrary.org/obo/CHEBI_35222 |
T39 | 73-80 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
T40 | 188-190 | Chemical | denotes | SL | http://purl.obolibrary.org/obo/CHEBI_74815 |
T41 | 212-223 | Chemical | denotes | application | http://purl.obolibrary.org/obo/CHEBI_33232 |
T42 | 231-238 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
T43 | 276-283 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
T44 | 474-481 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
T45 | 532-543 | Chemical | denotes | application | http://purl.obolibrary.org/obo/CHEBI_33232 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T31 | 0-200 | Sentence | denotes | We have recently designed and engineered a pan-CoV fusion inhibitor, EK1 peptide, which could inhibit infection of five human coronaviruses, including SARS-CoV and MERS-CoV, and three bat-SL-CoVs [7]. |
T32 | 201-437 | Sentence | denotes | Intranasal application of EK1 peptide before or after viral challenge, EK1 peptide can protect human DPP4-transgenic mice from MERS-CoV infection, suggesting its potential prophylactic and therapeutic effect against 2019-nCoV infection. |
T33 | 438-634 | Sentence | denotes | Once confirmed, we will develop EK1 peptide as a t prophylactic or therapeutic for intranasal application to prevent or treat infection by 2019-nCoV and other emerging coronaviruses in the future. |