PMC:7029759 / 15167-33636
Annnotations
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
331 | 17-26 | Species | denotes | 2019-nCoV | Tax:2697049 |
334 | 88-97 | Species | denotes | 2019-nCoV | Tax:2697049 |
335 | 556-561 | Species | denotes | Ebola | Tax:1570291 |
350 | 1105-1136 | Gene | denotes | angiotensin-converting enzyme 2 | Gene:59272 |
351 | 1138-1142 | Gene | denotes | ACE2 | Gene:59272 |
352 | 1292-1296 | Gene | denotes | ACE2 | Gene:59272 |
353 | 1597-1601 | Gene | denotes | ACE2 | Gene:59272 |
354 | 1086-1095 | Species | denotes | 2019-nCoV | Tax:2697049 |
355 | 1213-1229 | Species | denotes | SARS coronavirus | Tax:694009 |
356 | 1271-1282 | Species | denotes | coronavirus | Tax:11118 |
357 | 1581-1590 | Species | denotes | 2019-nCoV | Tax:2697049 |
358 | 1709-1718 | Species | denotes | 2019-nCoV | Tax:2697049 |
359 | 1572-1576 | Disease | denotes | SARS | MESH:D045169 |
360 | 1679-1683 | Disease | denotes | SARS | MESH:D045169 |
361 | 1733-1737 | Disease | denotes | SARS | MESH:D045169 |
362 | 1856-1865 | Disease | denotes | infection | MESH:D007239 |
363 | 1869-1873 | Disease | denotes | SARS | MESH:D045169 |
365 | 1912-1916 | Gene | denotes | ACE2 | Gene:59272 |
371 | 2016-2020 | Gene | denotes | ACE2 | Gene:59272 |
372 | 2062-2066 | Gene | denotes | ACE2 | Gene:59272 |
373 | 1979-1987 | Species | denotes | patients | Tax:9606 |
374 | 2389-2404 | Species | denotes | influenza virus | Tax:11308 |
375 | 2519-2530 | Chemical | denotes | sialic acid | MESH:D019158 |
397 | 2626-2630 | Gene | denotes | ACE2 | Gene:59272 |
398 | 2771-2775 | Gene | denotes | ACE2 | Gene:59272 |
399 | 3021-3025 | Gene | denotes | ACE2 | Gene:59272 |
400 | 3268-3272 | Gene | denotes | ACE2 | Gene:59272 |
401 | 3315-3319 | Gene | denotes | ACE2 | Gene:59272 |
402 | 2705-2706 | Gene | denotes | S | Gene:43740568 |
403 | 2989-2997 | Species | denotes | patients | Tax:9606 |
404 | 3140-3149 | Species | denotes | 2019-nCoV | Tax:2697049 |
405 | 3227-3236 | Species | denotes | 2019-nCoV | Tax:2697049 |
406 | 3351-3362 | Species | denotes | coronavirus | Tax:11118 |
407 | 4287-4291 | Species | denotes | mice | Tax:10090 |
408 | 3346-3350 | Species | denotes | NL63 | Tax:277944 |
409 | 2700-2704 | Disease | denotes | SARS | MESH:D045169 |
410 | 2907-2911 | Disease | denotes | SARS | MESH:D045169 |
411 | 2962-2966 | Disease | denotes | SARS | MESH:D045169 |
412 | 3063-3072 | Disease | denotes | infection | MESH:D007239 |
413 | 3218-3222 | Disease | denotes | SARS | MESH:D045169 |
414 | 3337-3341 | Disease | denotes | SARS | MESH:D045169 |
415 | 4104-4108 | Disease | denotes | MERS | MESH:D018352 |
416 | 4114-4118 | Disease | denotes | MERS | MESH:D018352 |
417 | 4167-4182 | Disease | denotes | viral infection | MESH:D001102 |
419 | 4530-4539 | Species | denotes | 2019-nCoV | Tax:2697049 |
438 | 4586-4590 | Gene | denotes | ACE2 | Gene:59272 |
439 | 4719-4723 | Gene | denotes | ACE2 | Gene:59272 |
440 | 4978-4982 | Gene | denotes | ACE2 | Gene:59272 |
441 | 5077-5081 | Gene | denotes | scFv | Gene:652070 |
442 | 5113-5117 | Gene | denotes | ACE2 | Gene:59272 |
443 | 5300-5304 | Gene | denotes | ACE2 | Gene:59272 |
444 | 5361-5365 | Gene | denotes | ACE2 | Gene:59272 |
445 | 5263-5268 | Gene | denotes | spike | Gene:43740568 |
446 | 4902-4907 | Gene | denotes | spike | Gene:43740568 |
447 | 4662-4667 | Gene | denotes | spike | Gene:43740568 |
448 | 4640-4645 | Species | denotes | human | Tax:9606 |
449 | 4698-4709 | Species | denotes | coronavirus | Tax:11118 |
450 | 4929-4938 | Species | denotes | 2019-nCoV | Tax:2697049 |
451 | 5176-5187 | Species | denotes | coronavirus | Tax:11118 |
452 | 5218-5222 | Gene | denotes | ACE2 | Gene:59272 |
453 | 4727-4735 | Disease | denotes | infected | MESH:D007239 |
454 | 4836-4845 | Disease | denotes | infection | MESH:D007239 |
455 | 4921-4925 | Disease | denotes | SARS | MESH:D045169 |
468 | 5452-5456 | Gene | denotes | ACE2 | Gene:59272 |
469 | 5618-5622 | Gene | denotes | ACE2 | Gene:59272 |
470 | 5841-5845 | Gene | denotes | ACE2 | Gene:59272 |
471 | 6020-6024 | Gene | denotes | ACE2 | Gene:59272 |
472 | 6190-6194 | Gene | denotes | ACE2 | Gene:59272 |
473 | 6609-6613 | Gene | denotes | scFv | Gene:652070 |
474 | 6629-6633 | Gene | denotes | ACE2 | Gene:59272 |
475 | 6367-6376 | Species | denotes | mammalian | Tax:9606 |
476 | 6499-6507 | Species | denotes | patients | Tax:9606 |
477 | 5485-5504 | Disease | denotes | 2019-nCoV infection | MESH:C000657245 |
478 | 5563-5567 | Disease | denotes | SARS | MESH:D045169 |
479 | 6125-6137 | Disease | denotes | inflammation | MESH:D007249 |
503 | 7504-7508 | Gene | denotes | ACE2 | Gene:59272 |
504 | 7595-7599 | Gene | denotes | ACE2 | Gene:59272 |
505 | 7688-7692 | Gene | denotes | ACE2 | Gene:59272 |
506 | 7914-7918 | Gene | denotes | ACE2 | Gene:59272 |
507 | 8100-8104 | Gene | denotes | ACE2 | Gene:59272 |
508 | 8258-8262 | Gene | denotes | ACE2 | Gene:59272 |
509 | 8405-8409 | Gene | denotes | ACE2 | Gene:70008 |
510 | 8486-8490 | Gene | denotes | ACE2 | Gene:70008 |
511 | 8591-8595 | Gene | denotes | ACE2 | Gene:70008 |
512 | 7129-7138 | Species | denotes | 2019-nCoV | Tax:2697049 |
513 | 7298-7307 | Species | denotes | 2019-nCoV | Tax:2697049 |
514 | 8413-8419 | Species | denotes | murine | Tax:10090 |
515 | 8752-8760 | Species | denotes | patients | Tax:9606 |
516 | 6969-6973 | Disease | denotes | SARS | MESH:D045169 |
517 | 7044-7048 | Disease | denotes | SARS | MESH:D045169 |
518 | 7109-7118 | Disease | denotes | infection | MESH:D007239 |
519 | 7663-7672 | Disease | denotes | infection | MESH:D007239 |
520 | 8136-8145 | Disease | denotes | infection | MESH:D007239 |
521 | 8377-8381 | Disease | denotes | SARS | MESH:D045169 |
522 | 8476-8481 | Disease | denotes | edema | MESH:D004487 |
523 | 8537-8548 | Disease | denotes | lung injury | MESH:D055370 |
524 | 8653-8662 | Disease | denotes | infection | MESH:D007239 |
525 | 8704-8719 | Disease | denotes | viral infection | MESH:D001102 |
527 | 8812-8816 | Gene | denotes | ACE2 | Gene:59272 |
552 | 9081-9085 | Gene | denotes | ACE2 | Gene:59272 |
553 | 9280-9284 | Gene | denotes | ACE2 | Gene:59272 |
554 | 9404-9408 | Gene | denotes | ACE2 | Gene:59272 |
555 | 9565-9569 | Gene | denotes | ACE2 | Gene:59272 |
556 | 9587-9591 | Gene | denotes | ACE2 | Gene:59272 |
557 | 9665-9669 | Gene | denotes | ACE2 | Gene:59272 |
558 | 9737-9741 | Gene | denotes | ACE2 | Gene:59272 |
559 | 9963-9967 | Gene | denotes | ACE2 | Gene:59272 |
560 | 10021-10025 | Gene | denotes | ACE2 | Gene:59272 |
561 | 10177-10181 | Gene | denotes | ACE2 | Gene:59272 |
562 | 9422-9423 | Gene | denotes | S | Gene:43740568 |
563 | 9118-9119 | Gene | denotes | S | Gene:43740568 |
564 | 8946-8957 | Species | denotes | coronavirus | Tax:11118 |
565 | 9131-9140 | Species | denotes | 2019-nCoV | Tax:2697049 |
566 | 9212-9222 | Species | denotes | SARS virus | Tax:694009 |
567 | 9324-9334 | Species | denotes | SARS virus | Tax:694009 |
568 | 9530-9539 | Species | denotes | 2019-nCoV | Tax:2697049 |
569 | 9614-9622 | Species | denotes | patients | Tax:9606 |
570 | 10063-10079 | Species | denotes | SARS coronavirus | Tax:694009 |
571 | 10209-10218 | Species | denotes | 2019-nCoV | Tax:2697049 |
572 | 10247-10255 | Species | denotes | patients | Tax:9606 |
573 | 10002-10007 | Species | denotes | human | Tax:9606 |
574 | 9005-9013 | Disease | denotes | infected | MESH:D007239 |
575 | 9417-9421 | Disease | denotes | SARS | MESH:D045169 |
615 | 10290-10294 | Gene | denotes | ACE2 | Gene:59272 |
616 | 10347-10351 | Gene | denotes | ACE2 | Gene:59272 |
617 | 10653-10657 | Gene | denotes | ACE2 | Gene:59272 |
618 | 10679-10683 | Gene | denotes | ACE2 | Gene:59272 |
619 | 10796-10800 | Gene | denotes | ACE2 | Gene:59272 |
620 | 10872-10886 | Gene | denotes | angiotensin II | Gene:183 |
621 | 10981-10985 | Gene | denotes | ACE2 | Gene:59272 |
622 | 11145-11149 | Gene | denotes | ACE2 | Gene:59272 |
623 | 11411-11417 | Gene | denotes | Ang1-8 | Gene:284 |
624 | 11654-11658 | Gene | denotes | ACE2 | Gene:59272 |
625 | 10310-10311 | Gene | denotes | S | Gene:43740568 |
626 | 10300-10309 | Species | denotes | 2019-nCoV | Tax:2697049 |
627 | 10437-10445 | Species | denotes | patients | Tax:9606 |
628 | 11010-11037 | Species | denotes | respiratory syncytial virus | Tax:12814 |
629 | 11045-11049 | Species | denotes | H5N1 | Tax:102793 |
630 | 11139-11144 | Species | denotes | human | Tax:9606 |
631 | 11231-11239 | Species | denotes | patients | Tax:9606 |
632 | 11701-11710 | Species | denotes | 2019-nCoV | Tax:2697049 |
633 | 11711-11719 | Species | denotes | patients | Tax:9606 |
634 | 11050-11059 | Species | denotes | influenza | Tax:11320 |
635 | 11477-11488 | Species | denotes | respiratory | Tax:12814 |
636 | 11151-11157 | Chemical | denotes | rhACE2 | |
637 | 11270-11276 | Chemical | denotes | rhACE2 | |
638 | 11534-11540 | Chemical | denotes | rhACE2 | |
639 | 10397-10406 | Disease | denotes | pneumonia | MESH:D011014 |
640 | 10451-10455 | Disease | denotes | SARS | MESH:D045169 |
641 | 10460-10479 | Disease | denotes | 2019-nCoV infection | MESH:C000657245 |
642 | 10488-10497 | Disease | denotes | pneumonia | MESH:D011014 |
643 | 10525-10540 | Disease | denotes | pulmonary edema | MESH:D011654 |
644 | 10545-10580 | Disease | denotes | acute respiratory distress syndrome | MESH:D012128 |
645 | 10582-10586 | Disease | denotes | ARDS | MESH:D012128 |
646 | 10626-10630 | Disease | denotes | ARDS | MESH:D012128 |
647 | 10841-10852 | Disease | denotes | lung injury | MESH:D055370 |
648 | 11002-11006 | Disease | denotes | ARDS | MESH:D012128 |
649 | 11063-11072 | Disease | denotes | infection | MESH:D007239 |
650 | 11208-11212 | Disease | denotes | ARDS | MESH:D012128 |
651 | 11216-11230 | Disease | denotes | critically ill | MESH:D016638 |
652 | 11599-11603 | Disease | denotes | ARDS | MESH:D012128 |
653 | 11693-11697 | Disease | denotes | ARDS | MESH:D012128 |
763 | 15215-15224 | Species | denotes | 2019-nCoV | Tax:2697049 |
673 | 11814-11818 | Gene | denotes | ACE2 | Gene:59272 |
674 | 11913-11917 | Gene | denotes | ACE2 | Gene:59272 |
675 | 12047-12051 | Gene | denotes | ACE2 | Gene:59272 |
676 | 12126-12130 | Gene | denotes | ACE2 | Gene:59272 |
677 | 12318-12322 | Gene | denotes | ACE2 | Gene:59272 |
678 | 12398-12402 | Gene | denotes | ACE2 | Gene:59272 |
679 | 12501-12505 | Gene | denotes | ACE2 | Gene:59272 |
680 | 12569-12573 | Gene | denotes | ACE2 | Gene:59272 |
681 | 12468-12469 | Gene | denotes | S | Gene:43740568 |
682 | 12354-12355 | Gene | denotes | S | Gene:43740568 |
683 | 11746-11755 | Species | denotes | 2019-nCoV | Tax:2697049 |
684 | 11756-11764 | Species | denotes | patients | Tax:9606 |
685 | 11838-11843 | Species | denotes | human | Tax:9606 |
686 | 12344-12353 | Species | denotes | 2019-nCoV | Tax:2697049 |
687 | 12458-12467 | Species | denotes | 2019-nCoV | Tax:2697049 |
688 | 12606-12616 | Species | denotes | SARS virus | Tax:694009 |
689 | 12635-12644 | Species | denotes | 2019-nCoV | Tax:2697049 |
690 | 11967-11971 | Disease | denotes | SARS | MESH:D045169 |
691 | 12256-12267 | Disease | denotes | lung injury | MESH:D055370 |
694 | 12698-12702 | Gene | denotes | ACE2 | Gene:59272 |
695 | 12742-12763 | Species | denotes | 2019-nCoV coronavirus | Tax:2697049 |
705 | 12798-12802 | Gene | denotes | ACE2 | Gene:59272 |
706 | 12930-12934 | Gene | denotes | ACE2 | Gene:59272 |
707 | 12980-12984 | Gene | denotes | ACE2 | Gene:59272 |
708 | 13020-13024 | Gene | denotes | ACE2 | Gene:59272 |
709 | 13076-13080 | Gene | denotes | ACE2 | Gene:59272 |
710 | 12824-12829 | Species | denotes | human | Tax:9606 |
711 | 13070-13075 | Species | denotes | human | Tax:9606 |
712 | 13137-13142 | Species | denotes | human | Tax:9606 |
713 | 13253-13258 | Species | denotes | human | Tax:9606 |
745 | 13562-13566 | Gene | denotes | ACE2 | Gene:70008 |
746 | 13662-13666 | Gene | denotes | ACE2 | Gene:70008 |
747 | 13962-13966 | Gene | denotes | CD16 | Gene:2214 |
748 | 14339-14343 | Gene | denotes | ACE2 | Gene:59272 |
749 | 14812-14816 | Gene | denotes | ACE2 | Gene:59272 |
750 | 14859-14863 | Gene | denotes | ACE2 | Gene:59272 |
751 | 14946-14950 | Gene | denotes | ACE2 | Gene:59272 |
752 | 15132-15136 | Gene | denotes | ACE2 | Gene:59272 |
753 | 15296-15300 | Gene | denotes | ACE2 | Gene:59272 |
754 | 13515-13523 | Species | denotes | patients | Tax:9606 |
755 | 13625-13629 | Species | denotes | mice | Tax:10090 |
756 | 14157-14162 | Species | denotes | mouse | Tax:10090 |
757 | 14554-14563 | Species | denotes | 2019-nCoV | Tax:2697049 |
758 | 14739-14761 | Species | denotes | human coronavirus NL63 | Tax:277944 |
759 | 14806-14811 | Species | denotes | human | Tax:9606 |
760 | 14914-14923 | Species | denotes | 2019-nCoV | Tax:2697049 |
761 | 15072-15082 | Species | denotes | SARS virus | Tax:694009 |
762 | 15126-15131 | Species | denotes | human | Tax:9606 |
764 | 14797-14801 | Species | denotes | NL63 | Tax:277944 |
765 | 14835-14839 | Species | denotes | NL63 | Tax:277944 |
766 | 13506-13514 | Disease | denotes | infected | MESH:D007239 |
767 | 13714-13726 | Disease | denotes | hypertension | MESH:D006973 |
768 | 14003-14011 | Disease | denotes | infected | MESH:D007239 |
769 | 14152-14156 | Disease | denotes | SARS | MESH:D045169 |
770 | 14230-14234 | Disease | denotes | SARS | MESH:D045169 |
771 | 14482-14491 | Disease | denotes | infection | MESH:D007239 |
772 | 14713-14717 | Disease | denotes | SARS | MESH:D045169 |
773 | 14824-14828 | Disease | denotes | SARS | MESH:D045169 |
774 | 14881-14885 | Disease | denotes | SARS | MESH:D045169 |
775 | 15165-15174 | Disease | denotes | infection | MESH:D007239 |
800 | 15498-15501 | Gene | denotes | CD4 | Gene:920 |
801 | 15508-15511 | Gene | denotes | CD4 | Gene:920 |
802 | 15639-15651 | Gene | denotes | CD4 receptor | Gene:920 |
803 | 15675-15680 | Gene | denotes | gp120 | Gene:3700 |
804 | 15719-15722 | Gene | denotes | CD4 | Gene:920 |
805 | 15941-15944 | Gene | denotes | CD4 | Gene:920 |
806 | 16038-16042 | Gene | denotes | CCR5 | Gene:1234 |
807 | 15834-15842 | Species | denotes | patients | Tax:9606 |
808 | 16158-16173 | Species | denotes | rhesus macaques | Tax:9544 |
809 | 16196-16231 | Species | denotes | simian-human immunodeficiency virus | Tax:57667 |
810 | 16265-16274 | Species | denotes | 2019-nCoV | Tax:2697049 |
811 | 16454-16463 | Species | denotes | 2019-nCoV | Tax:2697049 |
812 | 16478-16487 | Species | denotes | 2019-nCoV | Tax:2697049 |
813 | 16556-16567 | Species | denotes | respiratory | Tax:12814 |
814 | 15569-15572 | Species | denotes | HIV | Tax:12721 |
815 | 15751-15754 | Species | denotes | HIV | Tax:12721 |
816 | 16134-16137 | Species | denotes | HIV | Tax:12721 |
817 | 16257-16260 | Species | denotes | HIV | Tax:12721 |
818 | 16388-16391 | Species | denotes | HIV | Tax:12721 |
819 | 16617-16620 | Species | denotes | HIV | Tax:12721 |
820 | 15699-15711 | Disease | denotes | infected HIV | MESH:D015658 |
821 | 15776-15785 | Disease | denotes | infection | MESH:D007239 |
822 | 16599-16608 | Disease | denotes | infection | MESH:D007239 |
823 | 16635-16652 | Disease | denotes | chronic infection | MESH:D007239 |
851 | 16730-16734 | Gene | denotes | ACE2 | Gene:59272 |
852 | 16795-16799 | Gene | denotes | ACE2 | Gene:59272 |
853 | 16952-16956 | Gene | denotes | ACE2 | Gene:59272 |
854 | 17091-17095 | Gene | denotes | ACE2 | Gene:59272 |
855 | 17261-17265 | Gene | denotes | ACE2 | Gene:59272 |
856 | 17355-17359 | Gene | denotes | ACE2 | Gene:59272 |
857 | 17587-17591 | Gene | denotes | ACE2 | Gene:59272 |
858 | 17697-17701 | Gene | denotes | ACE2 | Gene:59272 |
859 | 17821-17825 | Gene | denotes | ACE2 | Gene:59272 |
860 | 17925-17929 | Gene | denotes | ACE2 | Gene:59272 |
861 | 17991-17995 | Gene | denotes | ACE2 | Gene:59272 |
862 | 18158-18169 | Gene | denotes | Fc receptor | |
863 | 18171-18175 | Gene | denotes | CD16 | Gene:2214 |
864 | 18451-18455 | Gene | denotes | ACE2 | Gene:59272 |
865 | 17506-17507 | Gene | denotes | S | Gene:43740568 |
866 | 17134-17142 | Species | denotes | patients | Tax:9606 |
867 | 17170-17178 | Species | denotes | patients | Tax:9606 |
868 | 17237-17246 | Species | denotes | 2019-nCoV | Tax:2697049 |
869 | 17247-17255 | Species | denotes | patients | Tax:9606 |
870 | 17496-17505 | Species | denotes | 2019-nCoV | Tax:2697049 |
871 | 18131-18140 | Species | denotes | 2019-nCoV | Tax:2697049 |
872 | 17647-17656 | Chemical | denotes | histidine | MESH:D006639 |
873 | 17184-17195 | Disease | denotes | lung injury | MESH:D055370 |
874 | 17487-17491 | Disease | denotes | SARS | MESH:D045169 |
875 | 17791-17795 | Disease | denotes | SARS | MESH:D045169 |
876 | 17942-17953 | Disease | denotes | lung injury | MESH:D055370 |
877 | 18254-18258 | Disease | denotes | MERS | MESH:D018352 |
LitCovid_Glycan-Motif-Structure
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T1 | 2519-2530 | https://glytoucan.org/Structures/Glycans/G81533KY | denotes | sialic acid |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T569 | 10639-10644 | NCBITaxon:10239 | denotes | viral |
T568 | 10653-10657 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T567 | 10679-10683 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T566 | 10702-10712 | GO:0010467 | denotes | expression |
T565 | 10744-10753 | PG_1 | denotes | S protein |
T564 | 10796-10800 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T563 | 10841-10845 | UBERON:0002048 | denotes | lung |
T562 | 10872-10886 | PR:000036009;DG_37 | denotes | angiotensin II |
T561 | 10933-10947 | DG_37;PR:000001251 | denotes | angiotensin II |
T560 | 10948-10964 | PR:000001251 | denotes | type 1a receptor |
T559 | 10981-10985 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T558 | 11010-11021 | UBERON:0001004;NCBITaxon:12814 | denotes | respiratory |
T557 | 11022-11031 | NCBITaxon:12814 | denotes | syncytial |
T556 | 11032-11037 | NCBITaxon:10239 | denotes | virus |
T555 | 11139-11144 | SP_6;NCBITaxon:9606;PG_10 | denotes | human |
T554 | 11145-11149 | PG_10;PR:000003622 | denotes | ACE2 |
T553 | 11324-11345 | UBERON:0004535 | denotes | cardiovascular system |
T552 | 11411-11415 | PR:000004020 | denotes | Ang1 |
T551 | 11463-11473 | GO:0065007 | denotes | modulation |
T550 | 11477-11488 | UBERON:0001004 | denotes | respiratory |
T549 | 11627-11633 | NCBITaxon:33208 | denotes | animal |
T548 | 11654-11658 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T547 | 11701-11710 | SP_7 | denotes | 2019-nCoV |
T546 | 11746-11755 | SP_7 | denotes | 2019-nCoV |
T545 | 11786-11799 | GO:0005576 | denotes | extracellular |
T544 | 11800-11806 | SO:0000417 | denotes | domain |
T543 | 11814-11818 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T542 | 11838-11843 | SP_6;NCBITaxon:9606 | denotes | human |
T541 | 11844-11858 | GO:0019814 | denotes | immunoglobulin |
T540 | 11864-11870 | SO:0000417 | denotes | domain |
T539 | 11913-11917 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T538 | 11967-11971 | SP_10;PG_9 | denotes | SARS |
T537 | 11972-11973 | PG_9;PG_1 | denotes | S |
T536 | 11974-11981 | PG_1 | denotes | protein |
T535 | 12026-12032 | SO:0000417 | denotes | domain |
T534 | 12047-12051 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T533 | 12112-12125 | GO:0005576 | denotes | extracellular |
T532 | 12126-12130 | G_3;PG_10 | denotes | ACE2 |
T531 | 12131-12137 | SO:0000417 | denotes | domain |
T530 | 12160-12169 | PG_1 | denotes | S protein |
T529 | 12256-12260 | UBERON:0002048 | denotes | lung |
T528 | 12318-12322 | G_3;PG_10 | denotes | ACE2 |
T527 | 12323-12329 | SO:0000417 | denotes | domain |
T526 | 12344-12353 | SP_7 | denotes | 2019-nCoV |
T525 | 12354-12363 | PG_1 | denotes | S protein |
T524 | 12398-12402 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T523 | 12458-12467 | SP_7 | denotes | 2019-nCoV |
T522 | 12468-12477 | PG_1 | denotes | S protein |
T521 | 12501-12505 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T520 | 12569-12573 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T519 | 12582-12589 | SO:0000417 | denotes | domains |
T518 | 12606-12610 | SP_10;NCBITaxon:10633 | denotes | SARS |
T517 | 12611-12616 | NCBITaxon:10239 | denotes | virus |
T516 | 12635-12644 | SP_7 | denotes | 2019-nCoV |
T515 | 13351-13357 | SO:0000417 | denotes | domain |
T514 | 13396-13400 | CHEBI:23888;CHEBI:23888 | denotes | drug |
T513 | 13464-13468 | CHEBI:23888;CHEBI:23888 | denotes | drug |
T512 | 13562-13566 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T511 | 13625-13629 | NCBITaxon:10088 | denotes | mice |
T510 | 13662-13666 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T509 | 13799-13807 | CHEBI:35224;CHEBI:35224 | denotes | effector |
T508 | 13828-13834 | SO:0000417 | denotes | domain |
T507 | 13861-13869 | CHEBI:36357;CHEBI:36357 | denotes | molecule |
T506 | 13895-13904 | GO:0030425;CL:0000451 | denotes | dendritic |
T505 | 13905-13910 | CL:0000451 | denotes | cells |
T504 | 13912-13923 | CL:0000235 | denotes | macrophages |
T503 | 13929-13949 | CL:0000623 | denotes | natural killer cells |
T502 | 13962-13966 | PR:000001483 | denotes | CD16 |
T501 | 13984-13989 | NCBITaxon:10239 | denotes | viral |
T500 | 14079-14085 | UBERON:0002405;GO:0006955 | denotes | immune |
T499 | 14086-14094 | GO:0006955 | denotes | response |
T498 | 14118-14123 | NCBITaxon:10239 | denotes | virus |
T497 | 14152-14156 | SP_10 | denotes | SARS |
T496 | 14157-14162 | NCBITaxon:10088 | denotes | mouse |
T495 | 14187-14197 | GO:0042571 | denotes | antibodies |
T494 | 14230-14234 | SP_10 | denotes | SARS |
T493 | 14239-14252 | GO:0001775 | denotes | activation of |
T492 | 14253-14263 | GO:0006909;CL:0000234 | denotes | phagocytic |
T491 | 14264-14269 | CL:0000234 | denotes | cells |
T490 | 14282-14292 | GO:0042571 | denotes | antibodies |
T489 | 14310-14315 | NCBITaxon:10239 | denotes | virus |
T488 | 14339-14343 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T487 | 14429-14437 | GO:0042571 | denotes | antibody |
T486 | 14554-14563 | SP_7 | denotes | 2019-nCoV |
T485 | 14696-14709 | BV_19 | denotes | pathogenicity |
T484 | 14713-14717 | SP_10 | denotes | SARS |
T483 | 14739-14744 | SP_6;NCBITaxon:9606 | denotes | human |
T482 | 14745-14756 | NCBITaxon:11118 | denotes | coronavirus |
T481 | 14806-14811 | SP_6;NCBITaxon:9606;PG_10 | denotes | human |
T480 | 14812-14816 | PG_10;PR:000003622 | denotes | ACE2 |
T479 | 14824-14828 | SP_10 | denotes | SARS |
T478 | 14840-14849 | PG_1 | denotes | S protein |
T477 | 14859-14863 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T476 | 14881-14885 | SP_10;PG_9 | denotes | SARS |
T475 | 14886-14887 | PG_9;PG_1 | denotes | S |
T474 | 14888-14895 | PG_1 | denotes | protein |
T473 | 14914-14923 | SP_7 | denotes | 2019-nCoV |
T472 | 14946-14950 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T471 | 15030-15035 | NCBITaxon:10239 | denotes | virus |
T470 | 15072-15076 | SP_10;NCBITaxon:10633 | denotes | SARS |
T469 | 15077-15082 | NCBITaxon:10239 | denotes | virus |
T468 | 15126-15131 | SP_6;NCBITaxon:9606;PG_10 | denotes | human |
T467 | 15132-15136 | PG_10;PR:000003622 | denotes | ACE2 |
T466 | 15215-15224 | SP_7 | denotes | 2019-nCoV |
T465 | 15296-15300 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T464 | 15498-15501 | PR:000001004 | denotes | CD4 |
T463 | 15508-15511 | PR:000001004 | denotes | CD4 |
T462 | 15512-15515 | GO:0071735 | denotes | IgG |
T461 | 15624-15631 | SO:0000417 | denotes | domains |
T460 | 15639-15642 | PR:000001004 | denotes | CD4 |
T459 | 15675-15680 | PR:000003229 | denotes | gp120 |
T458 | 15688-15698 | GO:0009986 | denotes | surface of |
T457 | 15719-15722 | PR:000001004 | denotes | CD4 |
T456 | 15723-15726 | GO:0071735 | denotes | IgG |
T455 | 15941-15944 | PR:000001004 | denotes | CD4 |
T454 | 15945-15948 | GO:0071735 | denotes | IgG |
T453 | 16038-16042 | PR:000001201 | denotes | CCR5 |
T452 | 16138-16146 | SO:0001060 | denotes | isolates |
T451 | 16158-16164 | NCBITaxon:9654 | denotes | rhesus |
T450 | 16165-16173 | NCBITaxon:9539 | denotes | macaques |
T449 | 16196-16202 | NCBITaxon:10633 | denotes | simian |
T448 | 16202-16203 | NCBITaxon:57667 | denotes | - |
T447 | 16203-16208 | SP_6;NCBITaxon:9606 | denotes | human |
T446 | 16226-16231 | NCBITaxon:10633 | denotes | virus |
T445 | 16265-16274 | SP_7 | denotes | 2019-nCoV |
T444 | 16294-16301 | NCBITaxon:10239 | denotes | viruses |
T443 | 16454-16463 | SP_7 | denotes | 2019-nCoV |
T442 | 16478-16487 | SP_7 | denotes | 2019-nCoV |
T441 | 16556-16567 | NCBITaxon:11886;UBERON:0001004 | denotes | respiratory |
T440 | 16568-16573 | NCBITaxon:10239 | denotes | virus |
T439 | 16730-16734 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T438 | 16781-16794 | GO:0005576 | denotes | extracellular |
T437 | 16795-16799 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T436 | 16895-16901 | SO:0000417 | denotes | domain |
T435 | 16938-16951 | GO:0005576 | denotes | extracellular |
T434 | 16952-16956 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T433 | 16969-16977 | GO:0032941 | denotes | secreted |
T432 | 16981-16988 | UBERON:0000479 | denotes | tissues |
T431 | 17017-17030 | GO:0005576 | denotes | extracellular |
T430 | 17031-17037 | SO:0000417 | denotes | domain |
T429 | 17091-17095 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T428 | 17184-17188 | UBERON:0002048 | denotes | lung |
T427 | 17237-17246 | SP_7 | denotes | 2019-nCoV |
T426 | 17261-17265 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T425 | 17355-17359 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T424 | 17487-17491 | SP_10 | denotes | SARS |
T423 | 17496-17505 | SP_7 | denotes | 2019-nCoV |
T422 | 17506-17515 | PG_1 | denotes | S protein |
T421 | 17587-17591 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T404 | 1892-1898 | CHEBI:38867;CHEBI:38867 | denotes | agents |
T403 | 1912-1916 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T402 | 2016-2020 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T401 | 2062-2066 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T400 | 2157-2162 | CHEBI:52217;CHEBI:52217 | denotes | agent |
T399 | 2178-2183 | NCBITaxon:10239 | denotes | virus |
T398 | 2389-2398 | NCBITaxon:7719 | denotes | influenza |
T397 | 2399-2404 | NCBITaxon:10239 | denotes | virus |
T396 | 2452-2460 | GO:0042571 | denotes | antibody |
T395 | 2519-2530 | CHEBI:26667;CHEBI:26667 | denotes | sialic acid |
T394 | 2543-2550 | GO:0009986 | denotes | surface |
T393 | 2626-2630 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T392 | 2678-2684 | SO:0000417 | denotes | domain |
T391 | 2700-2704 | SP_10;PG_9 | denotes | SARS |
T390 | 2705-2706 | PG_9;PG_1 | denotes | S |
T389 | 2707-2714 | PG_1 | denotes | protein |
T388 | 2749-2755 | SO:0000417 | denotes | domain |
T387 | 2771-2775 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T386 | 2825-2831 | SO:0000417 | denotes | domain |
T385 | 2907-2911 | SP_10 | denotes | SARS |
T384 | 2962-2966 | SP_10 | denotes | SARS |
T383 | 3021-3025 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T382 | 3140-3149 | SP_7 | denotes | 2019-nCoV |
T381 | 3218-3222 | SP_10 | denotes | SARS |
T380 | 3227-3236 | SP_7 | denotes | 2019-nCoV |
T379 | 3252-3264 | SO:0000409 | denotes | binding site |
T378 | 3268-3272 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T377 | 3315-3319 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T376 | 3320-3333 | SO:0000409 | denotes | binding sites |
T375 | 3337-3341 | SP_10 | denotes | SARS |
T374 | 3351-3362 | NCBITaxon:11118 | denotes | coronavirus |
T373 | 3443-3453 | GO:0042571 | denotes | antibodies |
T372 | 3504-3511 | UBERON:0000479 | denotes | tissues |
T371 | 3540-3545 | NCBITaxon:10239;GO:0035376 | denotes | viral |
T370 | 3546-3551 | GO:0035376 | denotes | entry |
T369 | 3689-3697 | NCBITaxon:2 | denotes | bacteria |
T368 | 3760-3769 | NCBITaxon:2 | denotes | bacterial |
T367 | 4092-4098 | SO:0000417 | denotes | domain |
T366 | 4104-4108 | SP_9 | denotes | MERS |
T365 | 4114-4118 | SP_9 | denotes | MERS |
T364 | 4167-4172 | NCBITaxon:10239;GO:0006260 | denotes | viral |
T363 | 4233-4239 | UBERON:0002405;GO:0006955 | denotes | immune |
T362 | 4240-4248 | GO:0006955 | denotes | response |
T361 | 4271-4276 | NCBITaxon:10239 | denotes | viral |
T360 | 4277-4283 | SO:0000417 | denotes | domain |
T359 | 4287-4291 | NCBITaxon:10088 | denotes | mice |
T358 | 4398-4404 | SO:0000417 | denotes | domain |
T357 | 5424-5432 | GO:0042571 | denotes | antibody |
T356 | 5452-5456 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T355 | 5485-5494 | SP_7 | denotes | 2019-nCoV |
T354 | 5563-5567 | SP_10 | denotes | SARS |
T353 | 5578-5589 | GO:0006260 | denotes | replication |
T352 | 5618-5622 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T351 | 5623-5631 | GO:0042571 | denotes | antibody |
T350 | 5690-5700 | GO:0042571 | denotes | antibodies |
T349 | 5820-5825 | NCBITaxon:10239 | denotes | viral |
T348 | 5841-5845 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T347 | 5854-5862 | GO:0042571 | denotes | antibody |
T346 | 5927-5936 | PG_1 | denotes | S protein |
T345 | 6020-6024 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T344 | 6025-6033 | GO:0042571 | denotes | antibody |
T343 | 6048-6056 | CHEBI:35224;CHEBI:35224 | denotes | effector |
T342 | 6104-6110 | SO:0000417 | denotes | domain |
T341 | 6171-6178 | UBERON:0000479 | denotes | tissues |
T340 | 6179-6189 | GO:0010467 | denotes | expressing |
T339 | 6190-6194 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T338 | 6251-6257 | SO:0000417 | denotes | domain |
T337 | 6324-6330 | SO:0000417 | denotes | domain |
T336 | 6367-6376 | NCBITaxon:40674 | denotes | mammalian |
T335 | 6377-6392 | GO:0006412 | denotes | cell production |
T334 | 6491-6495 | CHEBI:23888;CHEBI:23888 | denotes | drug |
T333 | 6629-6633 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T332 | 6653-6660 | SO:0000417 | denotes | domains |
T331 | 6737-6745 | NCBITaxon:2 | denotes | bacteria |
T330 | 6814-6821 | UBERON:0000479 | denotes | tissues |
T329 | 6870-6879 | CHEBI:36357;CHEBI:36357 | denotes | molecules |
T328 | 6895-6901 | SO:0000417 | denotes | domain |
T327 | 6969-6973 | SP_10 | denotes | SARS |
T326 | 7021-7027 | UBERON:0002405;GO:0006955 | denotes | immune |
T325 | 7028-7036 | GO:0006955 | denotes | response |
T324 | 7044-7048 | SP_10 | denotes | SARS |
T323 | 7129-7138 | SP_7 | denotes | 2019-nCoV |
T322 | 7192-7198 | UBERON:0002405;GO:0006955 | denotes | immune |
T321 | 7199-7207 | GO:0006955 | denotes | response |
T320 | 7217-7224 | NCBITaxon:10239 | denotes | viruses |
T319 | 7298-7307 | SP_7 | denotes | 2019-nCoV |
T318 | 7321-7327 | UBERON:0002405;GO:0006955 | denotes | immune |
T317 | 7328-7336 | GO:0006955 | denotes | response |
T316 | 7504-7508 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T315 | 7548-7554 | UBERON:0000062 | denotes | organs |
T314 | 7595-7599 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T313 | 7688-7692 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T312 | 7735-7739 | UBERON:0002048 | denotes | lung |
T311 | 7744-7760 | UBERON:0001555 | denotes | gastrointestinal |
T310 | 7761-7767 | UBERON:0000062 | denotes | organs |
T309 | 7779-7787 | CL:0002139 | denotes | vascular |
T308 | 7788-7799 | CL:0002139;UBERON:0001986 | denotes | endothelial |
T307 | 7800-7805 | CL:0002139 | denotes | cells |
T306 | 7818-7825 | UBERON:0000479 | denotes | tissues |
T305 | 7914-7918 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T304 | 7935-7947 | GO:0009986 | denotes | cell surface |
T303 | 8100-8104 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T302 | 8153-8158 | UBERON:0000170 | denotes | lungs |
T301 | 8188-8193 | UBERON:0000170 | denotes | lungs |
T300 | 8258-8262 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T299 | 8299-8303 | UBERON:0002048 | denotes | lung |
T298 | 8377-8381 | SP_10 | denotes | SARS |
T297 | 8392-8398 | SO:0000417 | denotes | domain |
T296 | 8405-8409 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T295 | 8413-8419 | NCBITaxon:39107 | denotes | murine |
T294 | 8420-8424 | UBERON:0002048 | denotes | lung |
T293 | 8425-8431 | UBERON:0000479 | denotes | tissue |
T292 | 8467-8475 | UBERON:0003215 | denotes | alveolar |
T291 | 8486-8490 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T290 | 8537-8541 | UBERON:0002048 | denotes | lung |
T289 | 8591-8595 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T288 | 8704-8709 | NCBITaxon:10239 | denotes | viral |
T287 | 88-97 | SP_7 | denotes | 2019-nCoV |
T286 | 149-154 | NCBITaxon:10239 | denotes | virus |
T285 | 194-204 | GO:0042571 | denotes | antibodies |
T284 | 299-309 | GO:0042571 | denotes | antibodies |
T283 | 367-375 | GO:0042571 | denotes | antibody |
T282 | 432-435 | BV_22 | denotes | RNA |
T281 | 436-441 | BV_22;NCBITaxon:10239 | denotes | virus |
T280 | 480-488 | CHEBI:60004;CHEBI:60004 | denotes | cocktail |
T279 | 489-497 | GO:0042571 | denotes | antibody |
T278 | 728-733 | NCBITaxon:10239 | denotes | viral |
T277 | 734-746 | CHEBI:17089;BV_11;CHEBI:17089 | denotes | glycoprotein |
T276 | 832-837 | NCBITaxon:10239 | denotes | viral |
T275 | 862-874 | GO:0009986 | denotes | cell surface |
T274 | 897-902 | NCBITaxon:10239 | denotes | virus |
T273 | 1008-1013 | NCBITaxon:10239 | denotes | viral |
T272 | 1086-1095 | SP_7 | denotes | 2019-nCoV |
T271 | 1105-1136 | PG_10;PR:000003622 | denotes | angiotensin-converting enzyme 2 |
T270 | 1138-1142 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T269 | 1213-1217 | SP_10 | denotes | SARS |
T268 | 1218-1229 | NCBITaxon:11118 | denotes | coronavirus |
T267 | 1258-1265 | NCBITaxon:10239 | denotes | viruses |
T266 | 1271-1282 | NCBITaxon:11118 | denotes | coronavirus |
T265 | 1292-1296 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T264 | 1309-1318 | PG_1 | denotes | S protein |
T263 | 1346-1355 | GO:0061025 | denotes | fusion of |
T262 | 1360-1365 | NCBITaxon:10239;GO:0036338 | denotes | viral |
T261 | 1366-1374 | GO:0036338 | denotes | membrane |
T260 | 1379-1392 | GO:0005886 | denotes | cell membrane |
T259 | 1423-1426 | BV_22 | denotes | RNA |
T258 | 1427-1432 | BV_22;NCBITaxon:10239 | denotes | virus |
T257 | 1438-1447 | GO:0006260 | denotes | replicate |
T256 | 1452-1458 | SO:0001026 | denotes | genome |
T255 | 1521-1529 | GO:0046903 | denotes | secreted |
T254 | 1572-1576 | SP_10 | denotes | SARS |
T253 | 1581-1590 | SP_7 | denotes | 2019-nCoV |
T252 | 1597-1601 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T251 | 1679-1683 | SP_10 | denotes | SARS |
T250 | 1709-1718 | SP_7 | denotes | 2019-nCoV |
T249 | 1733-1737 | SP_10 | denotes | SARS |
T248 | 1869-1873 | SP_10 | denotes | SARS |
T757 | 12698-12702 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T756 | 12742-12751 | SP_7 | denotes | 2019-nCoV |
T755 | 12752-12763 | NCBITaxon:11118 | denotes | coronavirus |
T754 | 12774-12787 | GO:0005576 | denotes | extracellular |
T753 | 12788-12794 | SO:0000417 | denotes | domain |
T752 | 12798-12802 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T751 | 12824-12829 | SP_6;NCBITaxon:9606 | denotes | human |
T750 | 12830-12844 | GO:0019814 | denotes | immunoglobulin |
T749 | 12848-12854 | SO:0000417 | denotes | domain |
T748 | 12891-12897 | SO:0000417 | denotes | domain |
T747 | 12910-12922 | GO:0046983 | denotes | dimerization |
T746 | 12930-12934 | G_3;PG_10 | denotes | ACE2 |
T745 | 12935-12942 | SO:0000417 | denotes | domains |
T744 | 12980-12984 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T743 | 13020-13024 | G_3;PG_10 | denotes | ACE2 |
T742 | 13025-13031 | SO:0000417 | denotes | domain |
T741 | 13070-13075 | SP_6;NCBITaxon:9606;PG_10 | denotes | human |
T740 | 13076-13080 | PG_10;PR:000003622 | denotes | ACE2 |
T739 | 13137-13142 | SP_6;NCBITaxon:9606 | denotes | human |
T738 | 13143-13157 | GO:0019814 | denotes | immunoglobulin |
T737 | 13253-13258 | SP_6;NCBITaxon:9606 | denotes | human |
T736 | 13259-13271 | CHEBI:60816;CHEBI:60816 | denotes | immunoglobin |
T735 | 4495-4501 | CHEBI:52217;CHEBI:52217 | denotes | agents |
T734 | 4530-4539 | SP_7 | denotes | 2019-nCoV |
T733 | 4575-4585 | GO:0010467 | denotes | expressing |
T732 | 4586-4590 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T731 | 4599-4603 | UBERON:0002048 | denotes | lung |
T730 | 4608-4624 | UBERON:0001555 | denotes | gastrointestinal |
T729 | 4625-4632 | UBERON:0000479 | denotes | tissues |
T728 | 4640-4645 | SP_6;NCBITaxon:9606 | denotes | human |
T727 | 4683-4690 | GO:0009986 | denotes | surface |
T726 | 4698-4709 | NCBITaxon:11118 | denotes | coronavirus |
T725 | 4719-4723 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T724 | 4754-4764 | GO:0035376 | denotes | cell entry |
T723 | 4882-4888 | SO:0000417 | denotes | domain |
T722 | 4921-4925 | SP_10 | denotes | SARS |
T721 | 4929-4938 | SP_7 | denotes | 2019-nCoV |
T720 | 4978-4982 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T719 | 5033-5041 | GO:0042571 | denotes | antibody |
T718 | 5045-5051 | SO:0000984 | denotes | single |
T717 | 5058-5066 | GO:0042571 | denotes | antibody |
T716 | 5113-5117 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T715 | 5176-5187 | NCBITaxon:11118 | denotes | coronavirus |
T714 | 5218-5222 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T713 | 5223-5236 | GO:0005576 | denotes | extracellular |
T712 | 5237-5243 | SO:0000417 | denotes | domain |
T711 | 5284-5290 | SO:0000417 | denotes | domain |
T710 | 5300-5304 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T709 | 5361-5365 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T619 | 8812-8816 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T618 | 8900-8908 | GO:0042571 | denotes | antibody |
T617 | 8914-8922 | CHEBI:36357;CHEBI:36357 | denotes | molecule |
T616 | 8946-8957 | NCBITaxon:11118 | denotes | coronavirus |
T615 | 9081-9085 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T614 | 9118-9127 | PG_1 | denotes | S protein |
T613 | 9131-9140 | SP_7 | denotes | 2019-nCoV |
T612 | 9166-9171 | NCBITaxon:10239 | denotes | virus |
T611 | 9212-9216 | SP_10;NCBITaxon:10633 | denotes | SARS |
T610 | 9217-9222 | NCBITaxon:10239 | denotes | virus |
T609 | 9280-9284 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T608 | 9324-9328 | SP_10;NCBITaxon:10633 | denotes | SARS |
T607 | 9329-9334 | NCBITaxon:10239 | denotes | virus |
T606 | 9404-9408 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T605 | 9417-9421 | SP_10;PG_9 | denotes | SARS |
T604 | 9422-9423 | PG_9;PG_1 | denotes | S |
T603 | 9424-9431 | PG_1 | denotes | protein |
T602 | 9497-9507 | GO:0042571 | denotes | antibodies |
T601 | 9530-9539 | SP_7 | denotes | 2019-nCoV |
T600 | 9565-9569 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T599 | 9587-9591 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T598 | 9665-9669 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T597 | 9711-9725 | GO:0019814 | denotes | immunoglobulin |
T596 | 9729-9735 | SO:0000417 | denotes | domain |
T595 | 9737-9741 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T594 | 9769-9777 | UBERON:0000104 | denotes | lifespan |
T593 | 9797-9805 | CHEBI:36357;CHEBI:36357 | denotes | molecule |
T592 | 9829-9837 | CHEBI:35224;CHEBI:35224 | denotes | effector |
T591 | 9855-9868 | UBERON:0002405 | denotes | immune system |
T590 | 9881-9886 | NCBITaxon:10239 | denotes | virus |
T589 | 9911-9917 | NCBITaxon:33208 | denotes | animal |
T588 | 9963-9967 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T587 | 9968-9981 | GO:0005576 | denotes | extracellular |
T586 | 9982-9988 | SO:0000417 | denotes | domain |
T585 | 10002-10007 | SP_6;NCBITaxon:9606 | denotes | human |
T584 | 10013-10019 | SO:0000417 | denotes | domain |
T583 | 10021-10025 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T582 | 10063-10067 | SP_10 | denotes | SARS |
T581 | 10068-10079 | NCBITaxon:11118 | denotes | coronavirus |
T580 | 10177-10181 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T579 | 10209-10218 | SP_7 | denotes | 2019-nCoV |
T578 | 10290-10294 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T577 | 10300-10309 | SP_7 | denotes | 2019-nCoV |
T576 | 10310-10319 | PG_1 | denotes | S protein |
T575 | 10347-10351 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T574 | 10451-10455 | SP_10 | denotes | SARS |
T573 | 10460-10469 | SP_7 | denotes | 2019-nCoV |
T572 | 10525-10534 | UBERON:0002048 | denotes | pulmonary |
T571 | 10551-10562 | UBERON:0001004 | denotes | respiratory |
T570 | 10598-10605 | NCBITaxon:10239 | denotes | viruses |
T420 | 17697-17701 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T419 | 17702-17715 | GO:0005576 | denotes | extracellular |
T418 | 17716-17722 | SO:0000417 | denotes | domain |
T417 | 17791-17795 | PR:000014459;SP_10;PG_9 | denotes | SARS |
T416 | 17796-17797 | PG_9;PG_1;PR:000005292 | denotes | S |
T415 | 17798-17805 | PG_1;PR:000005292 | denotes | protein |
T414 | 17821-17825 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T413 | 17925-17929 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T412 | 17942-17946 | UBERON:0002048 | denotes | lung |
T411 | 17991-17995 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
T410 | 18088-18096 | GO:0042571 | denotes | antibody |
T409 | 18131-18140 | SP_7 | denotes | 2019-nCoV |
T408 | 18171-18175 | PR:000001483 | denotes | CD16 |
T407 | 18240-18250 | GO:0042571 | denotes | antibodies |
T406 | 18254-18258 | SP_9 | denotes | MERS |
T405 | 18451-18455 | G_3;PG_10;PR:000003622 | denotes | ACE2 |
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T71 | 169-174 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T72 | 229-233 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
T73 | 367-375 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T74 | 432-435 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T75 | 489-497 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T76 | 734-746 | Body_part | denotes | glycoprotein | http://purl.org/sig/ont/fma/fma62925 |
T77 | 847-854 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T78 | 862-874 | Body_part | denotes | cell surface | http://purl.org/sig/ont/fma/fma67653 |
T79 | 862-866 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T80 | 1026-1030 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T81 | 1162-1166 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T82 | 1311-1318 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T83 | 1379-1392 | Body_part | denotes | cell membrane | http://purl.org/sig/ont/fma/fma63841 |
T84 | 1379-1383 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T85 | 1423-1426 | Body_part | denotes | RNA | http://purl.org/sig/ont/fma/fma67095 |
T86 | 1452-1458 | Body_part | denotes | genome | http://purl.org/sig/ont/fma/fma84116 |
T87 | 1470-1474 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T88 | 1546-1551 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T89 | 2067-2074 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T90 | 2452-2460 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T91 | 2538-2550 | Body_part | denotes | cell surface | http://purl.org/sig/ont/fma/fma67653 |
T92 | 2538-2542 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T93 | 2707-2714 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T94 | 2837-2848 | Body_part | denotes | amino acids | http://purl.org/sig/ont/fma/fma82739 |
T95 | 2915-2919 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T96 | 3026-3034 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T97 | 3045-3050 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T98 | 3504-3511 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T99 | 3630-3637 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T100 | 3797-3805 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T101 | 3974-3981 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T102 | 4081-4091 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
T103 | 4190-4194 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T104 | 4350-4355 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T105 | 4555-4560 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T106 | 4569-4574 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T107 | 4599-4603 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T108 | 4625-4632 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T109 | 4640-4650 | Body_part | denotes | human body | http://purl.org/sig/ont/fma/fma305853 |
T110 | 4668-4675 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T111 | 4736-4741 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T112 | 4754-4758 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T113 | 4908-4915 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T114 | 5033-5041 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T115 | 5058-5066 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T116 | 5269-5276 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T117 | 5424-5432 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T118 | 5457-5464 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T119 | 5623-5631 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T120 | 5854-5862 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T121 | 5929-5936 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T122 | 6025-6033 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T123 | 6171-6178 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T124 | 6377-6381 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T125 | 6814-6821 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T126 | 6992-6996 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
T127 | 7049-7056 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T128 | 7526-7530 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
T129 | 7710-7714 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
T130 | 7735-7739 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T131 | 7788-7805 | Body_part | denotes | endothelial cells | http://purl.org/sig/ont/fma/fma66772 |
T132 | 7800-7805 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T133 | 7818-7825 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T134 | 7935-7947 | Body_part | denotes | cell surface | http://purl.org/sig/ont/fma/fma67653 |
T135 | 7935-7939 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T136 | 7995-8002 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T137 | 8153-8158 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
T138 | 8188-8193 | Body_part | denotes | lungs | http://purl.org/sig/ont/fma/fma68877 |
T139 | 8299-8303 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T140 | 8366-8373 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T141 | 8420-8424 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T142 | 8425-8431 | Body_part | denotes | tissue | http://purl.org/sig/ont/fma/fma9637 |
T143 | 8467-8475 | Body_part | denotes | alveolar | http://purl.org/sig/ont/fma/fma264783 |
T144 | 8537-8541 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T145 | 8900-8908 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T146 | 8988-8993 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T147 | 9120-9127 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T148 | 9350-9355 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T149 | 9424-9431 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T150 | 9711-9725 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
T151 | 9855-9868 | Body_part | denotes | immune system | http://purl.org/sig/ont/fma/fma9825 |
T152 | 10312-10319 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T153 | 10658-10665 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T154 | 10684-10691 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T155 | 10746-10753 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T156 | 10801-10808 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T157 | 10841-10845 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T158 | 10902-10910 | Body_part | denotes | hormones | http://purl.org/sig/ont/fma/fma12278 |
T159 | 11324-11345 | Body_part | denotes | cardiovascular system | http://purl.org/sig/ont/fma/fma7161 |
T160 | 11819-11826 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T161 | 11844-11860 | Body_part | denotes | immunoglobulin G | http://purl.org/sig/ont/fma/fma62872 |
T162 | 11918-11929 | Body_part | denotes | amino acids | http://purl.org/sig/ont/fma/fma82739 |
T163 | 11974-11981 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T164 | 12162-12169 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T165 | 12256-12260 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T166 | 12356-12363 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T167 | 12406-12414 | Body_part | denotes | proteins | http://purl.org/sig/ont/fma/fma67257 |
T168 | 12470-12477 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T169 | 12574-12581 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T170 | 12655-12660 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T171 | 12713-12720 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T172 | 12830-12844 | Body_part | denotes | immunoglobulin | http://purl.org/sig/ont/fma/fma62871 |
T173 | 12953-12963 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
T174 | 12995-13002 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T175 | 13044-13055 | Body_part | denotes | amino acids | http://purl.org/sig/ont/fma/fma82739 |
T176 | 13081-13088 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T177 | 13143-13159 | Body_part | denotes | immunoglobulin G | http://purl.org/sig/ont/fma/fma62872 |
T178 | 13895-13910 | Body_part | denotes | dendritic cells | http://purl.org/sig/ont/fma/fma273565 |
T179 | 13905-13910 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T180 | 13912-13923 | Body_part | denotes | macrophages | http://purl.org/sig/ont/fma/fma63261 |
T181 | 13929-13949 | Body_part | denotes | natural killer cells | http://purl.org/sig/ont/fma/fma63147 |
T182 | 13944-13949 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T183 | 14012-14017 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T184 | 14264-14269 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T185 | 14354-14361 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T186 | 14429-14437 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T187 | 14616-14623 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T188 | 14649-14653 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T189 | 14842-14849 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T190 | 14888-14895 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T191 | 15512-15515 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T192 | 15569-15572 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
T193 | 15592-15599 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T194 | 15708-15711 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
T195 | 15712-15717 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T196 | 15723-15726 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T197 | 15751-15754 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
T198 | 15791-15798 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T199 | 15945-15948 | Body_part | denotes | IgG | http://purl.org/sig/ont/fma/fma62872 |
T200 | 16134-16137 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
T201 | 16257-16260 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
T202 | 16318-16322 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T203 | 16388-16391 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
T204 | 16617-16620 | Body_part | denotes | HIV | http://purl.org/sig/ont/fma/fma278683 |
T205 | 16834-16838 | Body_part | denotes | body | http://purl.org/sig/ont/fma/fma256135 |
T206 | 16981-16988 | Body_part | denotes | tissues | http://purl.org/sig/ont/fma/fma9637 |
T207 | 17096-17103 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T208 | 17184-17188 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T209 | 17337-17347 | Body_part | denotes | amino acid | http://purl.org/sig/ont/fma/fma82739 |
T210 | 17508-17515 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T211 | 17608-17615 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T212 | 17647-17656 | Body_part | denotes | histidine | http://purl.org/sig/ont/fma/fma82755 |
T213 | 17798-17805 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T214 | 17905-17912 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T215 | 17942-17946 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
T216 | 18088-18096 | Body_part | denotes | antibody | http://purl.org/sig/ont/fma/fma62871 |
T217 | 18186-18191 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T8 | 4599-4603 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T9 | 7548-7554 | Body_part | denotes | organs | http://purl.obolibrary.org/obo/UBERON_0000062 |
T10 | 7735-7739 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T11 | 7761-7767 | Body_part | denotes | organs | http://purl.obolibrary.org/obo/UBERON_0000062 |
T12 | 8299-8303 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T13 | 8420-8424 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T14 | 8425-8431 | Body_part | denotes | tissue | http://purl.obolibrary.org/obo/UBERON_0000479 |
T15 | 8537-8541 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T16 | 9855-9868 | Body_part | denotes | immune system | http://purl.obolibrary.org/obo/UBERON_0002405 |
T17 | 10841-10845 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T18 | 11324-11345 | Body_part | denotes | cardiovascular system | http://purl.obolibrary.org/obo/UBERON_0004535 |
T19 | 12256-12260 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T20 | 17184-17188 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
T21 | 17942-17946 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid_AGAC
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
p4504s27 | 4438-4447 | NegReg | denotes | eliminate |
p4551s19 | 10692-10701 | NegReg | denotes | decreased |
p4551s20 | 10702-10712 | MPA | denotes | expression |
p4580s38 | 14864-14870 | MPA | denotes | levels |
p4588s25 | 16044-16053 | PosReg | denotes | enhancing |
p4588s26 | 16054-16062 | MPA | denotes | affinity |
p4596s33 | 17723-17732 | NegReg | denotes | abolished |
p4596s34 | 17733-17742 | Enzyme | denotes | peptidase |
p4596s35 | 17743-17751 | MPA | denotes | activity |
p4596s39 | 17766-17770 | MPA | denotes | high |
p4596s40 | 17771-17779 | MPA | denotes | affinity |
p4596s41 | 17780-17787 | Interaction | denotes | binding |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T42 | 556-561 | Disease | denotes | Ebola | http://purl.obolibrary.org/obo/MONDO_0005737 |
T43 | 1213-1217 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T44 | 1572-1576 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T45 | 1679-1683 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T46 | 1733-1737 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T47 | 1856-1865 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T48 | 1869-1873 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T49 | 2389-2398 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T50 | 2700-2704 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T51 | 2907-2911 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T52 | 2962-2966 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T53 | 3063-3072 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T54 | 3218-3222 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T55 | 3337-3341 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T56 | 4167-4182 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
T57 | 4173-4182 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T58 | 4836-4845 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T59 | 4921-4925 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T60 | 5485-5504 | Disease | denotes | 2019-nCoV infection | http://purl.obolibrary.org/obo/MONDO_0100096 |
T61 | 5495-5504 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T62 | 5563-5567 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T63 | 6125-6137 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
T64 | 6969-6973 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T65 | 7044-7048 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T66 | 7109-7118 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T67 | 7663-7672 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T68 | 8136-8145 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T69 | 8377-8381 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T70 | 8531-8548 | Disease | denotes | acute lung injury | http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796 |
T72 | 8542-8548 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T73 | 8653-8662 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T74 | 8704-8719 | Disease | denotes | viral infection | http://purl.obolibrary.org/obo/MONDO_0005108 |
T75 | 8710-8719 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T76 | 9212-9216 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T77 | 9324-9328 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T78 | 9417-9421 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T79 | 10026-10028 | Disease | denotes | NN | http://purl.obolibrary.org/obo/MONDO_0009747 |
T80 | 10063-10067 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T81 | 10397-10406 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T82 | 10451-10455 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T83 | 10460-10479 | Disease | denotes | 2019-nCoV infection | http://purl.obolibrary.org/obo/MONDO_0100096 |
T84 | 10470-10479 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T85 | 10488-10497 | Disease | denotes | pneumonia | http://purl.obolibrary.org/obo/MONDO_0005249 |
T86 | 10525-10540 | Disease | denotes | pulmonary edema | http://purl.obolibrary.org/obo/MONDO_0006932 |
T87 | 10545-10580 | Disease | denotes | acute respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0006502 |
T88 | 10551-10580 | Disease | denotes | respiratory distress syndrome | http://purl.obolibrary.org/obo/MONDO_0009971 |
T89 | 10582-10586 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T90 | 10626-10630 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T91 | 10835-10852 | Disease | denotes | acute lung injury | http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796 |
T93 | 10846-10852 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T94 | 11002-11006 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T95 | 11050-11059 | Disease | denotes | influenza | http://purl.obolibrary.org/obo/MONDO_0005812 |
T96 | 11063-11072 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T97 | 11208-11212 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T98 | 11599-11603 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T99 | 11693-11697 | Disease | denotes | ARDS | http://purl.obolibrary.org/obo/MONDO_0006502 |
T100 | 11967-11971 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T101 | 12261-12267 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T102 | 12606-12610 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T103 | 13714-13726 | Disease | denotes | hypertension | http://purl.obolibrary.org/obo/MONDO_0005044 |
T104 | 14152-14156 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T105 | 14230-14234 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T106 | 14482-14491 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T107 | 14713-14717 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T108 | 14824-14828 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T109 | 14881-14885 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T110 | 15072-15076 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T111 | 15165-15174 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T112 | 15776-15785 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T113 | 16209-16225 | Disease | denotes | immunodeficiency | http://purl.obolibrary.org/obo/MONDO_0021094 |
T114 | 16599-16608 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T115 | 16643-16652 | Disease | denotes | infection | http://purl.obolibrary.org/obo/MONDO_0005550 |
T116 | 17189-17195 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
T117 | 17487-17491 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T118 | 17791-17795 | Disease | denotes | SARS | http://purl.obolibrary.org/obo/MONDO_0005091 |
T119 | 17947-17953 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T125 | 149-154 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T126 | 169-174 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T127 | 344-345 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T128 | 389-390 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T129 | 436-441 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T130 | 478-479 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T131 | 775-776 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T132 | 862-866 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T133 | 897-902 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T134 | 1026-1030 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T135 | 1040-1041 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T136 | 1147-1148 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T137 | 1162-1166 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T138 | 1173-1175 | http://purl.obolibrary.org/obo/CLO_0053794 | denotes | 41 |
T139 | 1258-1265 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T140 | 1366-1374 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T141 | 1379-1383 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T142 | 1384-1392 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T143 | 1427-1432 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T144 | 1470-1474 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T145 | 1546-1551 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T146 | 2178-2183 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T147 | 2399-2404 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T148 | 2502-2509 | http://purl.obolibrary.org/obo/CLO_0009985 | denotes | focuses |
T149 | 2538-2542 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T150 | 2720-2723 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T151 | 2858-2861 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T152 | 2915-2919 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T153 | 3045-3050 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T154 | 3177-3178 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T155 | 3562-3564 | http://purl.obolibrary.org/obo/CLO_0053799 | denotes | 45 |
T156 | 3689-3697 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
T157 | 3824-3825 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T158 | 3892-3895 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T159 | 3923-3935 | http://purl.obolibrary.org/obo/OBI_0000245 | denotes | organization |
T160 | 4006-4008 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T161 | 4123-4125 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T162 | 4190-4194 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T163 | 4319-4321 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T164 | 4350-4355 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T165 | 4395-4397 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T166 | 4448-4450 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T167 | 4468-4470 | http://purl.obolibrary.org/obo/CLO_0001382 | denotes | 48 |
T168 | 4555-4560 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T169 | 4569-4574 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T170 | 4599-4603 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T171 | 4599-4603 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T172 | 4640-4645 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T173 | 4736-4741 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T174 | 4754-4758 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T175 | 5142-5143 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T176 | 5281-5283 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T177 | 5366-5368 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T178 | 5371-5372 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T179 | 5729-5738 | http://purl.obolibrary.org/obo/CLO_0036932 | denotes | hybridoma |
T180 | 5768-5769 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T181 | 5948-5949 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T182 | 6101-6103 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T183 | 6248-6250 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T184 | 6321-6323 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T185 | 6350-6351 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T186 | 6377-6381 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T187 | 6575-6576 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T188 | 6635-6636 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T189 | 6737-6745 | http://purl.obolibrary.org/obo/NCBITaxon_2 | denotes | bacteria |
T190 | 6892-6894 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T191 | 7217-7224 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T192 | 7397-7398 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T193 | 7419-7420 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T194 | 7440-7442 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
T195 | 7548-7554 | http://purl.obolibrary.org/obo/UBERON_0003103 | denotes | organs |
T196 | 7735-7739 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T197 | 7735-7739 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T198 | 7761-7767 | http://purl.obolibrary.org/obo/UBERON_0003103 | denotes | organs |
T199 | 7788-7805 | http://purl.obolibrary.org/obo/CL_0000115 | denotes | endothelial cells |
T200 | 7935-7939 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T201 | 8153-8158 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
T202 | 8188-8193 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lungs |
T203 | 8299-8303 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T204 | 8299-8303 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T205 | 8338-8339 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T206 | 8357-8358 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T207 | 8389-8391 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T208 | 8420-8424 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T209 | 8420-8424 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T210 | 8537-8541 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T211 | 8537-8541 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T212 | 8669-8670 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T213 | 8840-8841 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T214 | 8988-8993 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T215 | 9056-9057 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T216 | 9166-9171 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T217 | 9217-9222 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T218 | 9329-9334 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T219 | 9350-9355 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T220 | 9540-9543 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T221 | 9595-9596 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T222 | 9726-9728 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T223 | 9742-9744 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T224 | 9855-9868 | http://purl.obolibrary.org/obo/UBERON_0002405 | denotes | immune system |
T225 | 9881-9886 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T226 | 9898-9904 | http://purl.obolibrary.org/obo/UBERON_0000473 | denotes | tested |
T227 | 9911-9917 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animal |
T228 | 9925-9926 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T229 | 10002-10007 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T230 | 10095-10096 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T231 | 10182-10184 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T232 | 10298-10299 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T233 | 10424-10425 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T234 | 10598-10605 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T235 | 10809-10812 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T236 | 10841-10845 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T237 | 10841-10845 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T238 | 11032-11037 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T239 | 11139-11144 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T240 | 11241-11242 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T241 | 11324-11345 | http://purl.obolibrary.org/obo/UBERON_0004535 | denotes | cardiovascular system |
T242 | 11324-11345 | http://www.ebi.ac.uk/efo/EFO_0000791 | denotes | cardiovascular system |
T243 | 11350-11351 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T244 | 11418-11425 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
T245 | 11556-11559 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T246 | 11627-11633 | http://purl.obolibrary.org/obo/NCBITaxon_33208 | denotes | animal |
T247 | 11659-11661 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T248 | 11836-11837 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T249 | 11838-11843 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T250 | 11861-11863 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T251 | 11880-11882 | http://purl.obolibrary.org/obo/CLO_0001236 | denotes | 2A |
T252 | 11930-11932 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
T253 | 12087-12088 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T254 | 12188-12189 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T255 | 12224-12232 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T256 | 12256-12260 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T257 | 12256-12260 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T258 | 12403-12405 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T259 | 12611-12616 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T260 | 12655-12660 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T261 | 12703-12705 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T262 | 12724-12725 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T263 | 12767-12768 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T264 | 12824-12829 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T265 | 12845-12847 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T266 | 12888-12890 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T267 | 12946-12947 | http://purl.obolibrary.org/obo/CLO_0001021 | denotes | B |
T268 | 12985-12987 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T269 | 13056-13058 | http://purl.obolibrary.org/obo/CLO_0050510 | denotes | 18 |
T270 | 13070-13075 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T271 | 13137-13142 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T272 | 13227-13228 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
T273 | 13239-13245 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signal |
T274 | 13251-13252 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T275 | 13253-13258 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T276 | 13348-13350 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T277 | 13370-13371 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T278 | 13648-13649 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T279 | 13667-13669 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T280 | 13681-13682 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T281 | 13825-13827 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T282 | 13895-13910 | http://purl.obolibrary.org/obo/CL_0000451 | denotes | dendritic cells |
T283 | 13929-13949 | http://purl.obolibrary.org/obo/CL_0000623 | denotes | natural killer cells |
T284 | 14012-14017 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T285 | 14046-14056 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
T286 | 14118-14123 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T287 | 14150-14151 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T288 | 14157-14162 | http://purl.obolibrary.org/obo/CLO_0007836 | denotes | mouse |
T289 | 14175-14177 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T290 | 14239-14249 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
T291 | 14253-14263 | http://purl.obolibrary.org/obo/CL_0000234 | denotes | phagocytic |
T292 | 14264-14269 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T293 | 14310-14315 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T294 | 14344-14346 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T295 | 14402-14403 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T296 | 14462-14463 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T297 | 14649-14653 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
T298 | 14672-14675 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T299 | 14739-14744 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T300 | 14777-14778 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T301 | 14806-14811 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T302 | 15012-15013 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T303 | 15030-15035 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T304 | 15077-15082 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T305 | 15126-15131 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T306 | 15275-15280 | http://purl.obolibrary.org/obo/UBERON_0001456 | denotes | faced |
T307 | 15301-15303 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T308 | 15328-15329 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T309 | 15411-15412 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T310 | 15442-15443 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T311 | 15498-15501 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
T312 | 15502-15504 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T313 | 15508-15511 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
T314 | 15557-15558 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T315 | 15639-15642 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
T316 | 15712-15717 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T317 | 15719-15722 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
T318 | 15941-15944 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
T319 | 15992-15993 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T320 | 16000-16007 | http://purl.obolibrary.org/obo/PR_000018263 | denotes | peptide |
T321 | 16104-16112 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T322 | 16158-16173 | http://purl.obolibrary.org/obo/NCBITaxon_9544 | denotes | rhesus macaques |
T323 | 16203-16208 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
T324 | 16226-16231 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T325 | 16247-16249 | http://purl.obolibrary.org/obo/CLO_0054055 | denotes | 71 |
T326 | 16294-16301 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
T327 | 16318-16328 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell types |
T328 | 16427-16428 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T329 | 16568-16573 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
T330 | 16735-16737 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T331 | 16871-16872 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T332 | 16892-16894 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T333 | 17146-17147 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T334 | 17184-17188 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T335 | 17184-17188 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T336 | 17199-17200 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T337 | 17266-17268 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T338 | 17370-17378 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T339 | 17743-17751 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T340 | 17942-17946 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
T341 | 17942-17946 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
T342 | 18003-18011 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activity |
T343 | 18158-18160 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
T344 | 18186-18191 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
T345 | 18199-18202 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
T346 | 18456-18458 | http://purl.obolibrary.org/obo/CLO_0052676 | denotes | Fc |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T57 | 734-746 | Chemical | denotes | glycoprotein | http://purl.obolibrary.org/obo/CHEBI_17089 |
T58 | 847-854 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T59 | 1105-1116 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
T60 | 1311-1318 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T61 | 2067-2074 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T62 | 2519-2530 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
T63 | 2526-2530 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T64 | 2707-2714 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T65 | 2837-2848 | Chemical | denotes | amino acids | http://purl.obolibrary.org/obo/CHEBI_33709 |
T66 | 2837-2842 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T67 | 2843-2848 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
T68 | 3026-3034 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T69 | 3630-3637 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T70 | 3797-3805 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T71 | 3974-3981 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T72 | 4081-4091 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
T73 | 4081-4086 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T74 | 4087-4091 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T75 | 4668-4675 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T76 | 4908-4915 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T77 | 5269-5276 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T78 | 5457-5464 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T79 | 5929-5936 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T80 | 6048-6056 | Chemical | denotes | effector | http://purl.obolibrary.org/obo/CHEBI_35224 |
T81 | 6491-6495 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
T82 | 6870-6879 | Chemical | denotes | molecules | http://purl.obolibrary.org/obo/CHEBI_25367 |
T83 | 7049-7056 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T84 | 7995-8002 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T85 | 8366-8373 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T86 | 8914-8922 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
T87 | 9120-9127 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T88 | 9424-9431 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T89 | 9797-9805 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
T90 | 9829-9837 | Chemical | denotes | effector | http://purl.obolibrary.org/obo/CHEBI_35224 |
T91 | 10026-10028 | Chemical | denotes | NN | http://purl.obolibrary.org/obo/CHEBI_73406 |
T92 | 10312-10319 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T93 | 10658-10665 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T94 | 10684-10691 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T95 | 10746-10753 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T96 | 10801-10808 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T97 | 10872-10886 | Chemical | denotes | angiotensin II | http://purl.obolibrary.org/obo/CHEBI_2719|http://purl.obolibrary.org/obo/CHEBI_48432|http://purl.obolibrary.org/obo/CHEBI_58506 |
T100 | 10872-10883 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
T101 | 10884-10886 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
T102 | 10902-10910 | Chemical | denotes | hormones | http://purl.obolibrary.org/obo/CHEBI_24621 |
T103 | 10933-10947 | Chemical | denotes | angiotensin II | http://purl.obolibrary.org/obo/CHEBI_2719|http://purl.obolibrary.org/obo/CHEBI_48432|http://purl.obolibrary.org/obo/CHEBI_58506 |
T106 | 10933-10944 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
T107 | 10945-10947 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
T108 | 11358-11360 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
T109 | 11418-11425 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
T110 | 11819-11826 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T111 | 11918-11929 | Chemical | denotes | amino acids | http://purl.obolibrary.org/obo/CHEBI_33709 |
T112 | 11918-11923 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T113 | 11924-11929 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
T114 | 11974-11981 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T115 | 12162-12169 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T116 | 12356-12363 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T117 | 12406-12414 | Chemical | denotes | proteins | http://purl.obolibrary.org/obo/CHEBI_36080 |
T118 | 12470-12477 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T119 | 12574-12581 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T120 | 12713-12720 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T121 | 12953-12963 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
T122 | 12953-12958 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T123 | 12959-12963 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T124 | 12995-13002 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T125 | 13044-13055 | Chemical | denotes | amino acids | http://purl.obolibrary.org/obo/CHEBI_33709 |
T126 | 13044-13049 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T127 | 13050-13055 | Chemical | denotes | acids | http://purl.obolibrary.org/obo/CHEBI_37527 |
T128 | 13081-13088 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T129 | 13396-13400 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
T130 | 13464-13468 | Chemical | denotes | drug | http://purl.obolibrary.org/obo/CHEBI_23888 |
T131 | 13799-13807 | Chemical | denotes | effector | http://purl.obolibrary.org/obo/CHEBI_35224 |
T132 | 13861-13869 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
T133 | 14069-14078 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
T134 | 14354-14361 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T135 | 14616-14623 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T136 | 14842-14849 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T137 | 14888-14895 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T138 | 15454-15463 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
T139 | 15592-15599 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T140 | 15791-15798 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T141 | 16000-16007 | Chemical | denotes | peptide | http://purl.obolibrary.org/obo/CHEBI_16670 |
T142 | 17096-17103 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T143 | 17207-17209 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
T144 | 17337-17347 | Chemical | denotes | amino acid | http://purl.obolibrary.org/obo/CHEBI_33709 |
T145 | 17337-17342 | Chemical | denotes | amino | http://purl.obolibrary.org/obo/CHEBI_46882 |
T146 | 17343-17347 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T147 | 17508-17515 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T148 | 17608-17615 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T149 | 17647-17656 | Chemical | denotes | histidine | http://purl.obolibrary.org/obo/CHEBI_27570 |
T150 | 17798-17805 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T151 | 17905-17912 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10 | 4167-4182 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
T11 | 4233-4248 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
T12 | 6125-6137 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
T13 | 6419-6432 | http://purl.obolibrary.org/obo/GO_0070085 | denotes | glycosylation |
T14 | 7021-7036 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
T15 | 7192-7207 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
T16 | 7321-7336 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
T17 | 8704-8719 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | viral infection |
T18 | 13229-13238 | http://purl.obolibrary.org/obo/GO_0046903 | denotes | secretion |
T19 | 14079-14094 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
T20 | 17360-17378 | http://purl.obolibrary.org/obo/GO_0008233 | denotes | peptidase activity |
T21 | 17733-17751 | http://purl.obolibrary.org/obo/GO_0008233 | denotes | peptidase activity |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T94 | 0-36 | Sentence | denotes | Proposal for new 2019-nCoV therapies |
T95 | 37-237 | Sentence | denotes | The simplest and most direct approach to combating 2019-nCoV during the outbreak would be one to neutralize the virus from entering cells, the function that antibodies normally perform in the body 39. |
T96 | 238-477 | Sentence | denotes | For the reasons mentioned above when discussing neutralizing antibodies, it will be difficult to validate a broadly neutralizing antibody quickly, and a challenge to make sure that the mutating RNA virus will not escape its neutralization. |
T97 | 478-629 | Sentence | denotes | A cocktail antibody approach could be undertaken as was explored to treat the Ebola pandemic 40, but would add complexity to the manufacturing process. |
T98 | 630-756 | Sentence | denotes | However, there is another strategy to pursue in this scenario that does not rely on targeting the viral glycoprotein directly. |
T99 | 757-940 | Sentence | denotes | In this strategy, a neutralizing effect could be obtained by targeting the viral receptor protein on the cell surface, thereby blocking the virus from binding to it and gaining entry. |
T100 | 941-1039 | Sentence | denotes | Fortunately, scientists have already uncovered the identity of the viral receptor in cell culture. |
T101 | 1040-1248 | Sentence | denotes | A recent pre-print publication found that the 2019-nCoV uses the angiotensin-converting enzyme 2 (ACE2) as a receptor for cell entry 41, which is the same receptor that the SARS coronavirus uses for entry 42. |
T102 | 1249-1404 | Sentence | denotes | For both viruses, the coronavirus binds to ACE2 through its S protein on the virion, where after fusion of the viral membrane and cell membrane will occur. |
T103 | 1405-1552 | Sentence | denotes | Subsequently, the RNA virus will replicate its genome inside the cell, and ultimately make new virions that will be secreted to infect other cells. |
T104 | 1553-1719 | Sentence | denotes | The coincidence of SARS and 2019-nCoV using ACE2 receptor opens up the possibility of using the extensive research studied on SARS entry and applying it to 2019-nCoV. |
T105 | 1720-1881 | Sentence | denotes | Based on the SARS literature, several potential blocking strategies could be considered, which were shown to be effective in preventing infection in SARS models. |
T106 | 1883-1925 | Sentence | denotes | Blocking agents that bind to ACE2 receptor |
T107 | 1926-2021 | Sentence | denotes | The first strategy would consist of administering to patients an agent that would bind to ACE2. |
T108 | 2022-2163 | Sentence | denotes | The key advantage here is that the host ACE2 protein will not change, so there is no concern about escape from binding the therapeutic agent. |
T109 | 2164-2372 | Sentence | denotes | Moreover, the virus will not have the ability to mutate and bind an entirely new host receptor in the time frame of this outbreak; such functional relationships are established by evolution over long periods. |
T110 | 2373-2575 | Sentence | denotes | By analogy, the influenza virus changes the mutations on its surface to escape antibody neutralization every year, but it always focuses on using sialic acid on the cell surface as an entry receptor 43. |
T111 | 2576-2631 | Sentence | denotes | There are two known options for agents to bind to ACE2. |
T112 | 2632-2801 | Sentence | denotes | The first is using the small receptor-binding domain (RBD) from the SARS S protein that has been shown to be the key domain that binds the ACE2 receptor during entry 44. |
T113 | 2802-2931 | Sentence | denotes | Administration of this domain, 193 amino acids in size, has been shown to effectively block the entry of SARS in cell culture 44. |
T114 | 2932-3085 | Sentence | denotes | It is well within reason that SARS RBD could be given to patients, thereby binding their ACE2 proteins on target cells, preventing infection ( Figure 1). |
T115 | 3086-3195 | Sentence | denotes | There is also the potential for the equivalent RBD of 2019-nCoV to be produced and used as a therapy as well. |
T116 | 3196-3565 | Sentence | denotes | This strategy assumes SARS and 2019-nCoV share the same binding site on ACE2, which is highly likely given the similar ACE2 binding sites of SARS and NL63 coronavirus The small size of the therapy, similar in size in nanobody domains from camelid antibodies, would enhance the perfusion of the biologic into tissues to more effectively bind to viral entry receptors 45. |
T117 | 3566-3749 | Sentence | denotes | In regards to the outbreak situation that is ongoing, the small protein facilitates the rapid production of the therapy in bacteria potentially, which would help production yields 19. |
T118 | 3750-3950 | Sentence | denotes | Moreover, bacterial production would allow RBD proteins to be produced in a wide range of production facilities today in China, which already has numerous contract research organization operations 46. |
T119 | 3951-4109 | Sentence | denotes | Alternatively, the RBD protein could be attached to an Fc fragment for extended circulation, which was done for an equivalent 212 amino acid domain from MERS. |
T120 | 4110-4295 | Sentence | denotes | The MERS RBD-Fc fusion demonstrated the ability to block viral infection toward cell receptors, as well as to stimulate an immune response against that specific viral domain in mice 47. |
T121 | 4296-4471 | Sentence | denotes | Of note, since the RBD-Fc fusion would bind to normal cells, one would want to eliminate cytotoxic Fc domain functions through mutations that eliminate Fc receptor binding 48. |
T122 | 4472-4481 | Sentence | denotes | Figure 1. |
T123 | 4483-4561 | Sentence | denotes | Therapeutic agents that could be used to block 2019-nCoV from infecting cells. |
T124 | 4562-4651 | Sentence | denotes | Target cells expressing ACE2 include lung and gastrointestinal tissues in the human body. |
T125 | 4652-4765 | Sentence | denotes | The large spike protein on the surface of the coronavirus binds to ACE2 on infected cells, leading to cell entry. |
T126 | 4766-4846 | Sentence | denotes | Three proposed strategies would block this interaction would abrogate infection. |
T127 | 4847-5014 | Sentence | denotes | In the first, the receptor-binding domain (RBD) of the spike protein from SARS or 2019-nCoV would be administered, thereby binding ACE2 and saturating available sites. |
T128 | 5015-5141 | Sentence | denotes | Alternatively, an antibody or single chain antibody fragment (scFv) could be administered against ACE2 to accomplish the same. |
T129 | 5142-5277 | Sentence | denotes | A third strategy would target the coronavirus virions directly by using the ACE2 extracellular domain as bait to bind to spike protein. |
T130 | 5278-5370 | Sentence | denotes | An Fc domain fused to ACE2 would facilitate prolonged circulation of the biologic (ACE2-Fc). |
T131 | 5371-5517 | Sentence | denotes | A second, similar strategy would be to administer an antibody that would bind to ACE2 protein, thereby preventing 2019-nCoV infection ( Figure 1). |
T132 | 5518-5608 | Sentence | denotes | This strategy was shown to effectively block SARS entry and replication in experiments 42. |
T133 | 5609-5785 | Sentence | denotes | While no ACE2 antibody sequences are published in literature indexes, monoclonal antibodies do exist and the associated hybridoma sequences could be cloned in a matter of days. |
T134 | 5786-5937 | Sentence | denotes | There would be no concern for any viral escape from an ACE2 binding antibody, which is an advantage over neutralizing approaches against the S protein. |
T135 | 5938-6043 | Sentence | denotes | There are a couple of design considerations when thinking about how to employ the ACE2 antibody strategy. |
T136 | 6044-6195 | Sentence | denotes | Any effector functions would need to be removed from the Fc domain 49, such that inflammation would not be caused in different tissues expressing ACE2. |
T137 | 6196-6290 | Sentence | denotes | This would retain the long-half life endowed by the Fc domain without any of the side effects. |
T138 | 6291-6533 | Sentence | denotes | The downside of including the Fc domain is the need to use a more expensive mammalian cell production system to preserve proper glycosylation, which would decrease the turnaround time for getting the drug to patients in the outbreak scenario. |
T139 | 6534-6634 | Sentence | denotes | Alternatively, one could just administer a single chain variable fragment (scFv) that binds to ACE2. |
T140 | 6635-6709 | Sentence | denotes | A nanobody or VHH domains from camelids are another option as well 50, 51. |
T141 | 6710-6822 | Sentence | denotes | These could be produced in bacteria, and its small size would allow for rapid permeation into different tissues. |
T142 | 6823-6902 | Sentence | denotes | The downside is the shorter half-life of these molecules without the Fc domain. |
T143 | 6903-6954 | Sentence | denotes | There are several limitations to these two options. |
T144 | 6955-7239 | Sentence | denotes | Regarding the SARS RBD strategy, the body would likely develop an immune response to the SARS protein eventually, although the key intervention period of infection to combat 2019-nCoV would fall under this window of time, where after an immune response for both viruses would develop. |
T145 | 7240-7443 | Sentence | denotes | Alternatively, if one were to use the homologous RBD from 2019-nCoV itself, this immune response would likely be very advantageous since it could yield both a blocking effect and a vaccination effect 52. |
T146 | 7444-7673 | Sentence | denotes | For both strategies, the dose that would be needed to block ACE2 receptors in the body across different organs is unknown, and as is the percentage of ACE2 receptors that would need to be saturated in order to slow the infection. |
T147 | 7674-7883 | Sentence | denotes | The number of ACE2 receptors in the body, which are found in lung and gastrointestinal organs along with vascular endothelial cells among other tissues 53, could ultimately prove prohibitive for this strategy. |
T148 | 7884-8033 | Sentence | denotes | Moreover, the turnover of the ACE2 receptor on the cell surface would also influence how often the therapeutic protein would need to be administered. |
T149 | 8034-8211 | Sentence | denotes | To solve this issue, one could increase the concentration of anti-ACE2 therapy at the crucial site of infection in the lungs, via local administration to lungs via nebulization. |
T150 | 8212-8337 | Sentence | denotes | Lastly, there is the possibility that binding ACE2 directly could paradoxically worsen lung physiology and clinical symptoms. |
T151 | 8338-8552 | Sentence | denotes | A study found that a fusion protein of SARS RBD to Fc domain bound ACE2 in murine lung tissue after administration, exacerbating alveolar edema via ACE2 interaction, which normally counteracts acute lung injury 54. |
T152 | 8553-8720 | Sentence | denotes | This suggests that if one were use an ACE2 binding strategy, it would be best employed early during infection or as a prophylaxis to block the initial viral infection. |
T153 | 8721-8810 | Sentence | denotes | Ultimately, clinical trials in patients would need to investigate these potential issues. |
T154 | 8812-8839 | Sentence | denotes | ACE2 immunoadhesin strategy |
T155 | 8840-9014 | Sentence | denotes | A potentially more promising strategy would be to create an antibody-like molecule that would bind to the coronavirus itself, rather than shielding cells from being infected. |
T156 | 9015-9184 | Sentence | denotes | For this strategy, it is proposed to use a soluble version of the ACE2 receptor that would bind to the S protein of 2019-nCoV thereby neutralizing the virus ( Figure 1). |
T157 | 9185-9271 | Sentence | denotes | Again, the research on the SARS virus suggests this strategy is potentially promising. |
T158 | 9272-9370 | Sentence | denotes | Soluble ACE2 receptor was demonstrated to block the SARS virus from infecting cells in culture 42. |
T159 | 9371-9570 | Sentence | denotes | The reported affinity of soluble ACE2 for the SARS S protein was 1.70 nM, which is comparable to the affinities of monoclonal antibodies 55; it is likely that 2019-nCoV has similar affinity for ACE2. |
T160 | 9571-9887 | Sentence | denotes | In order to use ACE2 as a therapy to treat patients, it would be advisable to convert soluble ACE2 into an immunoadhesin format fused to an immunoglobulin Fc domain (ACE2-Fc), thereby extending the lifespan of the circulating molecule, while also recruiting effector functions of the immune system against the virus. |
T161 | 9888-10137 | Sentence | denotes | While not tested in an animal model, a previous study demonstrated that an ACE2 extracellular domain fused to the human IgG1 domain (ACE2-NN-Ig) was effective in neutralizing SARS coronavirus in vitro, with a 50% inhibitory concentration of 2 nM 56. |
T162 | 10138-10256 | Sentence | denotes | This study provides evidence then that ACE2-Fc could similarly inhibit 2019-nCoV in vitro and potentially in patients. |
T163 | 10257-10423 | Sentence | denotes | An additional advantage of using ACE2 as a 2019-nCoV S protein neutralizing agent is that ACE2 administration could also directly treat the pneumonia pathophysiology. |
T164 | 10424-10593 | Sentence | denotes | A portion of patients with SARS and 2019-nCoV infection develop pneumonia, which is characterized by pulmonary edema and acute respiratory distress syndrome (ARDS) 1, 2. |
T165 | 10594-10765 | Sentence | denotes | The viruses may, in part, cause ARDS through viral-induced ACE2 protein shedding and ACE2 protein decreased expression, both of which are mediated by S protein binding 54. |
T166 | 10766-10968 | Sentence | denotes | Administration of recombinant ACE2 protein has been shown to improve acute lung injury through decreasing angiotensin II levels and the hormones subsequent binding to angiotensin II type 1a receptor 57. |
T167 | 10969-11080 | Sentence | denotes | Recombinant ACE2 can also reduce ARDS in respiratory syncytial virus 58 and H5N1 influenza 59 infection models. |
T168 | 11081-11240 | Sentence | denotes | Based on these promising preclinical studies, recombinant human ACE2 (rhACE2) was moved into clinical trials in order to treat ARDS in critically ill patients. |
T169 | 11241-11349 | Sentence | denotes | A phase I trial demonstrated rhACE2 was well tolerated with no effects seen on the cardiovascular system 60. |
T170 | 11350-11503 | Sentence | denotes | A phase II trial demonstrated on-target efficacy in reducing Ang1-8 peptide levels, but did not show significant modulation of respiratory parameters 61. |
T171 | 11504-11720 | Sentence | denotes | It remains to be seen whether rhACE2 administration has the same clinical benefits in treating ARDS that have been seen in animal models, and whether ACE2-Fc administration could alleviate ARDS in 2019-nCoV patients. |
T172 | 11721-11884 | Sentence | denotes | The proposed therapy for 2019-nCoV patients would consist of the extracellular domain of the ACE2 protein fused to a human immunoglobulin G Fc domain ( Figure 2A). |
T173 | 11885-12071 | Sentence | denotes | Studies have shown that the ACE2 amino acids 18 – 615 appear to be sufficient for SARS S protein binding 62, which also covers the peptidase domain necessary for ACE2 enzymatic function. |
T174 | 12072-12268 | Sentence | denotes | It is possible a smaller portion of the extracellular ACE2 domain would be adequate for S protein binding, although a smaller version would lack enzyme activity beneficial in treating lung injury. |
T175 | 12269-12415 | Sentence | denotes | Further studies are needed to define the minimal ACE2 domain necessary for 2019-nCoV S protein binding to construct even smaller ACE2-Fc proteins. |
T176 | 12416-12661 | Sentence | denotes | While we do not know the structure of the 2019-nCoV S protein or how it binds to the ACE2 receptor yet, it is reasonable for now to assume that the same ACE2 protein domains utilized by the SARS virus are also bound by 2019-nCoV to infect cells. |
T177 | 12662-12671 | Sentence | denotes | Figure 2. |
T178 | 12673-12764 | Sentence | denotes | TherapeuticDesign of the ACE2-Fc fusion protein as a therapy against 2019-nCoV coronavirus. |
T179 | 12765-12883 | Sentence | denotes | ( A) The extracellular domain of ACE2 is appended onto the human immunoglobulin Fc domain, including the hinge region. |
T180 | 12884-13015 | Sentence | denotes | The Fc domain facilitates dimerization of two ACE2 domains. ( B) The amino acid sequence of the ACE2-Fc fusion protein is provided. |
T181 | 13016-13116 | Sentence | denotes | The ACE2 domain consists of amino acids 18–615 of the human ACE2 protein (blue; UniProtKB - Q9BYF1). |
T182 | 13117-13226 | Sentence | denotes | The sequence of the human immunoglobulin G isotype 1 constant region is provided (green; UniProtKB - P01857). |
T183 | 13227-13326 | Sentence | denotes | A secretion signal from a human immunoglobin heavy chain is provided (red; UniProtKB - A0A0C4DH39). |
T184 | 13327-13524 | Sentence | denotes | The advantage of the Fc domain is endowing a longer-half life of the drug, which could enable healthcare workers to potentially be given drug doses prophylactically before seeing infected patients. |
T185 | 13525-13730 | Sentence | denotes | Indeed, the half-life of recombinant ACE2 was extended from less than two hours to over one week in mice when formatted as a recombinant ACE2-Fc therapy in a study evaluating treatment for hypertension 63. |
T186 | 13731-14018 | Sentence | denotes | One difference from the prior blocking agent strategies is that the effector functions of the Fc domain could be retained in this molecule, allowing recruitment of dendritic cells, macrophages, and natural killer cells through the CD16 receptor against viral particles or infected cells. |
T187 | 14019-14325 | Sentence | denotes | This may facilitate faster activation of the host antiviral immune response and elimination of the virus, which was illustrated in a SARS mouse model where Fc engaging antibodies were more potent in eliminating SARS via activation of phagocytic cells compared to antibodies that neutralized virus alone 64. |
T188 | 14326-14660 | Sentence | denotes | Overall, the ACE2-Fc fusion protein would have many of the same benefits of a traditional neutralizing antibody that would be sought as a treatment for the infection, but represent one with maximal breadth and potency since the 2019-nCoV could not escape its neutralization, given the same protein is also its receptor for cell entry. |
T189 | 14661-14899 | Sentence | denotes | Indeed, it has been shown that the pathogenicity of SARS versus the more mild human coronavirus NL63 was related to a lower affinity of NL63 for human ACE2 versus SARS, with NL63 S protein reducing ACE2 levels less than SARS S protein 65. |
T190 | 14900-15036 | Sentence | denotes | Therefore, if 2019-nCoV were to try to escape ACE2 neutralization via decreasing affinity, it would mutate into a less pathogenic virus. |
T191 | 15037-15208 | Sentence | denotes | This is similar to the re-emergent SARS virus in 2003-2004, which had lower affinity for human ACE2 and resulted in less severe infection and no secondary transmission 66. |
T192 | 15209-15358 | Sentence | denotes | Thus, 2019-nCoV could be presented with an evolutionary trap when faced with potential ACE2-Fc therapy, leading toward a more benign clinical course. |
T193 | 15359-15587 | Sentence | denotes | To give some additional support to the potential of a receptor-immunoadhesin being a potential antiviral strategy, it should be noted that CD4-Fc or CD4-IgG was one of the early agents developed as a potential HIV medication 67. |
T194 | 15588-15718 | Sentence | denotes | The protein contained the first two domains of the CD4 receptor that are known to bind gp120 on the surface of infected HIV cells. |
T195 | 15719-15786 | Sentence | denotes | CD4-IgG was shown to neutralize HIV in vitro, preventing infection. |
T196 | 15787-15911 | Sentence | denotes | The protein was also safe when administered in patients, although only limited-to-mild clinical benefit was achieved 68, 69. |
T197 | 15912-16250 | Sentence | denotes | Updated enhanced versions of CD4-IgG have been developed that additionally have a small peptide derived from the co-receptor, CCR5, enhancing affinity and giving even more potent neutralizing activity, essentially 100% of HIV isolates and making rhesus macaques resistant to multiple simian-human immunodeficiency virus challenges 70, 71. |
T198 | 16251-16464 | Sentence | denotes | While HIV and 2019-nCoV are very different viruses, with different cell types, kinetics, and clinical courses, the previous results with HIV are encouraging that this could be a therapeutic strategy for 2019-nCoV. |
T199 | 16465-16697 | Sentence | denotes | If anything, 2019-nCoV is likely more amenable to this neutralizing therapy given that the respiratory virus will only cause an acute infection, unlike HIV, which causes chronic infection in hosts with different cellular reservoirs. |
T200 | 16698-16921 | Sentence | denotes | One potential limitation of the ACE2-Fc strategy is that the increase in levels of extracellular ACE2 could have unknown effects on the body, particularly when elevated for a prolonged time via Fc domain extended half-life. |
T201 | 16922-17068 | Sentence | denotes | Small levels of extracellular ACE2 are already secreted by tissues, so the circulation of this extracellular domain would not be unprecedented 72. |
T202 | 17069-17289 | Sentence | denotes | Moreover, recombinant ACE2 protein was well-tolerated by healthy patients in a phase I trial, and by patients with lung injury in a phase II trial, suggesting treating 2019-nCoV patients with ACE2-Fc will also tolerated. |
T203 | 17290-17516 | Sentence | denotes | If investigators are still concerned, critical amino acid(s) for ACE2 peptidase activity could be mutated to abolish the native function of this sequence, while retaining high affinity binding for SARS and 2019-nCoV S protein. |
T204 | 17517-17809 | Sentence | denotes | Indeed, this possibility was previously investigated in generating an ACE2 and IgG1 fusion protein, which showed that mutation of histidine residues at position 374 and 378 of the ACE2 extracellular domain abolished peptidase activity, but retained high affinity binding to SARS S protein 56. |
T205 | 17810-18029 | Sentence | denotes | Of course, ACE2 peptidase mutation would eliminate the beneficial effects from the recombinant protein delivery of ACE2 in treating lung injury, so it is recommended that retaining ACE2 enzyme activity be pursued first. |
T206 | 18030-18262 | Sentence | denotes | Another potential concern is that receptor binding via an antibody format could inadvertently direct 2019-nCoV toward infecting Fc receptor (CD16) positive cells, which has been shown in vitro for neutralizing antibodies in MERS 73. |
T207 | 18263-18365 | Sentence | denotes | It’s unclear what clinical significance this would have, and to what extent this would happen in vivo. |
T208 | 18366-18469 | Sentence | denotes | Ultimately, clinical trials will be needed to delineate any specific side effects of ACE2-Fc treatment. |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T12 | 8476-8481 | Phenotype | denotes | edema | http://purl.obolibrary.org/obo/HP_0000969 |
T13 | 8531-8548 | Phenotype | denotes | acute lung injury | http://www.orpha.net/ORDO/Orphanet_178320 |
T14 | 10397-10406 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T15 | 10488-10497 | Phenotype | denotes | pneumonia | http://purl.obolibrary.org/obo/HP_0002090 |
T16 | 10525-10540 | Phenotype | denotes | pulmonary edema | http://purl.obolibrary.org/obo/HP_0100598 |
T17 | 10551-10571 | Phenotype | denotes | respiratory distress | http://purl.obolibrary.org/obo/HP_0002098 |
T18 | 10835-10852 | Phenotype | denotes | acute lung injury | http://www.orpha.net/ORDO/Orphanet_178320 |
T19 | 13714-13726 | Phenotype | denotes | hypertension | http://purl.obolibrary.org/obo/HP_0000822 |
T20 | 15158-15174 | Phenotype | denotes | severe infection | http://purl.obolibrary.org/obo/HP_0032169 |
T21 | 16209-16225 | Phenotype | denotes | immunodeficiency | http://purl.obolibrary.org/obo/HP_0002721 |
T22 | 16635-16652 | Phenotype | denotes | chronic infection | http://purl.obolibrary.org/obo/HP_0031035 |