PMC:7029452 / 1304-3229 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7029452","sourcedb":"PMC","sourceid":"7029452","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7029452","text":"Background\nA novel coronavirus (severe acute respiratory syndrome coronavirus 2, SARS-CoV-2) causing a cluster of respiratory infections (coronavirus disease 2019, COVID-19) in Wuhan, China, was identified on 7 January 2020 [1]. Twenty-seven patients with pneumonia had initially been reported, with an epidemiological link to a live animal market that was closed and disinfected on 1 January [1]. From 20 January, the number of notifications of cases rose dramatically, and as at 12 February 2020, 45,179 cases of SARS-CoV-2 have been confirmed, including 1,116 deaths [2]. Most of the cases (n = 44,665) were reported in 31 provinces and autonomous regions of China and 514 cases were reported in 25 other countries in Asia, Australia, Europe and North America [2]. To date, the primary source of infection remains unknown and could still be active. Human-to-human transmission was observed early after the emergence of this new virus in China and abroad, including family clusters and healthcare settings. The current outbreak dynamics strongly indicate sustained human-to-human transmission.\nStrengthened surveillance of COVID-19 cases was implemented in France on 10 January 2020. The objective of the surveillance is to identify imported cases early and to prevent secondary transmission whether in the community or among healthcare workers (HCW). Investigations are carried out among contacts immediately upon illness onset and a follow-up procedure is initiated according to the evaluated level of infection risk.\nHere we describe the real-time implementation of this surveillance scheme for the first three imported cases of COVID-19 identified in France, who were confirmed on 24 January 2020 in persons with a recent stay in Wuhan. Two cases were diagnosed in Paris and one in Bordeaux. We present data until 12 February on the follow-up of the cases’ contacts initiated immediately upon confirmation of 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