PMC:7025468 / 40047-40573 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7025468","sourcedb":"PMC","sourceid":"7025468","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7025468","text":"At day 1 of HIV-1 infection, we observed enhanced release of IL-1β, followed by increased IL-1β mRNA and miR-146a expression at day two. Decreased TRAF6 expression, a known miR-146a target, is associated with increased HIV-1 replication (47). We observed decreased TRAF6 expression upon infection with HIV-1 at the gene expression level. IRAK1 protein expression levels were also decreased following HIV-1 infection. These findings are consistent with previous reports that HIV-1 decreases IRAK1 and TRAF6 expression (47, 55).","tracks":[{"project":"TEST0","denotations":[{"id":"32117283-101-107-3683954","span":{"begin":238,"end":240},"obj":"[\"22140520\"]"},{"id":"32117283-101-107-3683955","span":{"begin":518,"end":520},"obj":"[\"22140520\"]"},{"id":"32117283-105-111-3683956","span":{"begin":522,"end":524},"obj":"[\"25472883\"]"}],"attributes":[{"subj":"32117283-101-107-3683954","pred":"source","obj":"TEST0"},{"subj":"32117283-101-107-3683955","pred":"source","obj":"TEST0"},{"subj":"32117283-105-111-3683956","pred":"source","obj":"TEST0"}]},{"project":"2_test","denotations":[{"id":"32117283-22140520-35221760","span":{"begin":238,"end":240},"obj":"22140520"},{"id":"32117283-22140520-35221761","span":{"begin":518,"end":520},"obj":"22140520"},{"id":"32117283-25472883-35221762","span":{"begin":522,"end":524},"obj":"25472883"}],"attributes":[{"subj":"32117283-22140520-35221760","pred":"source","obj":"2_test"},{"subj":"32117283-22140520-35221761","pred":"source","obj":"2_test"},{"subj":"32117283-25472883-35221762","pred":"source","obj":"2_test"}]},{"project":"MyTest","denotations":[{"id":"32117283-22140520-35221760","span":{"begin":238,"end":240},"obj":"22140520"},{"id":"32117283-22140520-35221761","span":{"begin":518,"end":520},"obj":"22140520"},{"id":"32117283-25472883-35221762","span":{"begin":522,"end":524},"obj":"25472883"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"attributes":[{"subj":"32117283-22140520-35221760","pred":"source","obj":"MyTest"},{"subj":"32117283-22140520-35221761","pred":"source","obj":"MyTest"},{"subj":"32117283-25472883-35221762","pred":"source","obj":"MyTest"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"TEST0","color":"#eceb93","default":true},{"id":"2_test","color":"#d193ec"},{"id":"MyTest","color":"#93ecb7"}]}]}}