PMC:7019868 / 5619-6464
Annnotations
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 99 | 115-119 | Species | denotes | PEDV | Tax:28295 |
| 100 | 387-394 | Chemical | denotes | iPEDVPT | |
| 101 | 460-467 | Chemical | denotes | iPEDVPT | |
| 102 | 536-543 | Chemical | denotes | iPEDVPT | |
| 103 | 544-547 | Chemical | denotes | P96 |
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T28 | 80-84 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T29 | 348-352 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T30 | 514-518 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T31 | 587-591 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T32 | 697-701 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T33 | 767-771 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
| T34 | 788-792 | Body_part | denotes | gene | http://purl.org/sig/ont/fma/fma74402 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T57 | 80-84 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T58 | 187-189 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
| T59 | 228-235 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | viruses |
| T60 | 348-352 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T61 | 373-378 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T62 | 424-425 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T63 | 471-476 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T64 | 514-518 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T65 | 587-591 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T66 | 659-661 | http://purl.obolibrary.org/obo/CLO_0001407 | denotes | 52 |
| T67 | 697-701 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T68 | 754-759 | http://purl.obolibrary.org/obo/NCBITaxon_10239 | denotes | virus |
| T69 | 767-771 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T70 | 788-792 | http://purl.obolibrary.org/obo/OGG_0000000002 | denotes | gene |
| T71 | 809-810 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T21 | 413-422 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | virulence |
| T22 | 413-422 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | virulence |
| T23 | 835-844 | http://purl.obolibrary.org/obo/GO_0016032 | denotes | virulence |
| T24 | 835-844 | http://purl.obolibrary.org/obo/GO_0009405 | denotes | virulence |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T35 | 0-236 | Sentence | denotes | In the present study, we utilized reverse genetics to examine the role of the S gene in the attenuation process of PEDV using the highly virulent and attenuated G2b PEDV Pintung (PEDVPT) 52 strains, the PEDVPT-P5 and PEDVPT-P96 viruses. |
| T36 | 237-312 | Sentence | denotes | Nonetheless, our findings were discordant with previous reported data [17]. |
| T37 | 313-423 | Sentence | denotes | We found that replacement of the S gene with the iPEDVPT-P5 virus enabled iPEDVPT-P96 to regain its virulence. |
| T38 | 424-548 | Sentence | denotes | A reciprocal approach revealed that iPEDVPT-P5 virus became partly attenuated after the S gene was exchanged to iPEDVPT-P96. |
| T39 | 549-669 | Sentence | denotes | Collectively, we concluded that the S gene is of critical importance to the attenuation process of the PEDVPT 52 strain. |
| T40 | 670-760 | Sentence | denotes | However, mutation in the S gene alone could not completely attenuate the iPEDVPT-P5 virus. |
| T41 | 761-845 | Sentence | denotes | Thus, gene(s) other than S gene could also play a role in determining the virulence. |