PMC:7017962 / 2132-3456 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7017962","sourcedb":"PMC","sourceid":"7017962","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7017962","text":"As part of CDC’s Emergency Operations Center activation, CDC personnel assist state and local health departments with the evaluation of 2019-nCoV PUIs. Public health laboratories were not yet conducting 2019-nCoV testing during the period covered by this report, while awaiting Food and Drug Administration emergency use authorization for the test. (The authorization occurred on February 4*). Therefore, all testing was conducted at CDC. A call center was staffed by a team of physicians and nurses 24 hours per day. During January 17–31, criteria used to determine whether a person was considered to be a PUI included presence of fever and symptoms of lower respiratory tract illness (e.g., cough or difficulty breathing) in addition to epidemiologic risk. Epidemiologic risk factors included history of travel from Wuhan City, close contact with a patient with laboratory-confirmed 2019-nCoV infection, or close contact with an ill PUI. Given the evolving understanding of 2019-nCoV epidemiology, testing was recommended for some persons who did not strictly meet the PUI definition, based on clinical discretion. For clinical inquiries that resulted in 2019-nCoV testing, real-time reverse transcription polymerase chain reaction testing was conducted at CDC using methods developed specifically to detect 2019-nCoV 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