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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7014672","sourcedb":"PMC","sourceid":"7014672","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7014672","text":"Using the duration of stay in Wuhan and the symptom onset date, we obtained a range of possible values for the incubation period of each case. We fitted three parametric forms for the incubation period distribution to these ranges: the Weibull distribution, the gamma distribution and the lognormal distribution. We used a Bayesian approach to fitting that allows for the use of prior knowledge to inform the analysis. We specified strictly positive flat prior probability distributions for the parameter values of the three distributions (Supplementary Material S2), which ensured our estimates are conservative. Because of the sufficient number of observations, the impact of the priors on the outcome was negligible. We used a uniform prior probability distribution over the exposure interval for the moment of infection for each case. We sampled from the posterior distribution using the rstan package [9] in R software version 3.6.0 (R Foundation, Vienna, Austria) (Supplementary Material S3).","tracks":[{"project":"LitCovid-PubTator","denotations":[{"id":"43","span":{"begin":814,"end":823},"obj":"Disease"}],"attributes":[{"id":"A43","pred":"tao:has_database_id","subj":"43","obj":"MESH:D007239"},{"subj":"43","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T16","span":{"begin":814,"end":823},"obj":"Disease"}],"attributes":[{"id":"A16","pred":"mondo_id","subj":"T16","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"subj":"T16","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T12","span":{"begin":76,"end":77},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T13","span":{"begin":321,"end":322},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T14","span":{"begin":563,"end":565},"obj":"http://purl.obolibrary.org/obo/CLO_0008922"},{"id":"T15","span":{"begin":563,"end":565},"obj":"http://purl.obolibrary.org/obo/CLO_0050052"},{"id":"T16","span":{"begin":728,"end":729},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T17","span":{"begin":859,"end":868},"obj":"http://purl.obolibrary.org/obo/UBERON_0001353"}],"attributes":[{"subj":"T12","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T13","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T14","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T15","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T16","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T17","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T2","span":{"begin":262,"end":267},"obj":"Chemical"},{"id":"T3","span":{"begin":563,"end":565},"obj":"Chemical"},{"id":"T4","span":{"begin":994,"end":996},"obj":"Chemical"}],"attributes":[{"id":"A2","pred":"chebi_id","subj":"T2","obj":"http://purl.obolibrary.org/obo/CHEBI_30212"},{"id":"A3","pred":"chebi_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/CHEBI_29387"},{"id":"A4","pred":"chebi_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/CHEBI_29388"},{"subj":"T2","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T27","span":{"begin":0,"end":142},"obj":"Sentence"},{"id":"T28","span":{"begin":143,"end":312},"obj":"Sentence"},{"id":"T29","span":{"begin":313,"end":418},"obj":"Sentence"},{"id":"T30","span":{"begin":419,"end":613},"obj":"Sentence"},{"id":"T31","span":{"begin":614,"end":719},"obj":"Sentence"},{"id":"T32","span":{"begin":720,"end":838},"obj":"Sentence"},{"id":"T33","span":{"begin":839,"end":998},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T27","pred":"source","obj":"LitCovid-sentences"},{"subj":"T28","pred":"source","obj":"LitCovid-sentences"},{"subj":"T29","pred":"source","obj":"LitCovid-sentences"},{"subj":"T30","pred":"source","obj":"LitCovid-sentences"},{"subj":"T31","pred":"source","obj":"LitCovid-sentences"},{"subj":"T32","pred":"source","obj":"LitCovid-sentences"},{"subj":"T33","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PubTator","color":"#93ecdf","default":true},{"id":"LitCovid-PD-MONDO","color":"#ecc593"},{"id":"LitCovid-PD-CLO","color":"#ab93ec"},{"id":"LitCovid-PD-CHEBI","color":"#95ec93"},{"id":"LitCovid-sentences","color":"#ec93af"}]}]}}