PMC:7001239 / 7822-9030 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7001239","sourcedb":"PMC","sourceid":"7001239","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7001239","text":"Comparison with other emerging coronaviruses in the past allows to put into perspective the available information regarding the transmission patterns of 2019-nCoV. Figure 3 shows the combinations of R0 and k that are most likely at this stage of the epidemic. Our estimates of R0 and k are more similar to previous estimates focusing on early human-to-human transmission of SARS-CoV in Beijing and Singapore [7] than of Middle East respiratory syndrome-related coronavirus (MERS-CoV) [9]. The spread of MERS-CoV was characterised by small clusters of transmission following repeated instances of animal-to-human transmission events, mainly driven by the occurrence of superspreading events in hospital settings. MERS-CoV could however not sustain human-to-human transmission beyond a few generations [12]. Conversely, the international spread of SARS-CoV lasted for 9 months and was driven by sustained human-to-human transmission, with occasional superspreading events. It led to more than 8,000 cases around the world and required extensive efforts by public health authorities to be contained [13]. Our assessment of the early transmission of 2019-nCoV suggests that 2019-nCoV might follow a similar 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