PMC:6964229 / 10572-13279 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/6964229","sourcedb":"PMC","sourceid":"6964229","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6964229","text":"Baseline characteristics and mitral valve repair details\nBaseline characteristics of the whole study group are presented in Table 1. Median patient age was 66.5 (IQR 57.8–73.8) years and the majority of patients were male. The repair and procedure details are presented in Table 2. A full ring was used in all patients; the majority of patients (n = 456; 94.2%) underwent either a Physio I (n = 223; 46.1%) or Physio II (n = 233; 48.1%) ring (Edwards Lifesciences, Irvine, CA, USA) implantation. In 42 (8.7%) patients, a ring size 30 or smaller was implanted.\nTable 1: Baseline characteristics\nn = 484\nAge (years) 66.5 (57.8–73.8)\nGender (female) 171 (35.3)\nBody surface area (m2) 1.93 ± 0.22\nNYHA\n I 146 (30.2)\n II 243 (50.2)\n III–IV 95 (19.6)\nHypertension 221 (45.7)\nAtrial fibrillation 172 (35.5)\nRenal impairment (ml/min/1.73 m2)\n Moderate (CC 50–85) 226 (46.7)\n Severe (CC \u003c50) 41 (8.5)\nDiabetes mellitus 22 (4.5)\nChronic lung disease 42 (8.7)\nMitral annular calcification 49 (10.1)\nEchocardiographic characteristics\n LVEF ≤60% 134 (27.7)\n LVEDD (mm)a 54 ± 7\n LVESD (mm)a 33 ± 7\n LAD (mm)a 45.0 (40.0–49.0)\nEuroSCORE II 1.76 (0.99–3.24)\nDegenerative disease subtype\n Barlow’s disease 140 (28.9)\n Forme fruste Barlow’s disease 51 (10.5)\nSite of leaflet prolapse\n Posterior leaflet 299 (61.8)\n  Single scallop prolapse 234 (48.3)\n Anterior leaflet 41 (8.5)\n Bileaflet 144 (29.7)\nData are presented as n (%) and means ± SD or medians (IQR).\na Available for ≥95% of patients.\nCC: creatinine clearance; IQR: interquartile range; LAD: left atrial diameter; LVEDD: left ventricular end-diastolic diameter; LVEF: left ventricular ejection fraction; LVESD: left ventricular end-systolic diameter; NYHA: New York Heart Association; SD: standard deviation.\nTable 2: Mitral valve repair details\nn = 484\nMitral valve annulus\n Plication 102 (21.1)\nAnterior mitral valve leaflet repair (neochords) 125 (25.8)\nPosterior mitral valve leaflet\n Resection 321 (66.3)\n Leaflet sliding 222 (45.9)\n Neochords 206 (42.6)\n Chordal transfer 9 (1.9)\n Indentation closure 85 (17.6)\nCommissural repair 111 (22.9)\nAnnuloplasty ring type\n Physio I ring 223 (46.1)\n Physio II ring 233 (48.1)\n Other 28 (5.8)\nAnnuloplasty ring size\n 24 1 (0.2)\n 26 10 (2.1)\n 28 31 (6.4)\n 30 62 (12.8)\n 32 112 (23.1)\n 34 98 (20.3)\n 36 77 (15.9)\n 38 52 (10.7)\n 40 41 (8.5)\nIntraoperative mitral valve gradient (mmHg) 1.66 (1.16–2.40)\nConcomitant procedures\n Tricuspid valve repair 321 (51.4)\n Radiofrequency ablation for atrial fibrillation 148 (30.6)\n Coronary artery bypass surgery 96 (19.8)\n Aortic valve intervention 28 (5.8)\nData are presented as n (%) and medians (IQR).\nIQR: interquartile 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