PMC:6723065 / 10902-11570 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/6723065","sourcedb":"PMC","sourceid":"6723065","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6723065","text":"Effects of Memantine on sleep disturbances have been evaluated in a multicenter study, in which [45] patients with RBD were included. Memantine, a glutamatergic antagonist, might reduce these disorders, but its validity has been limited by the absence of PSG to support RBD diagnosis [52]. Sodium oxybate, an agent used to treat narcolepsy, has been documented to be effective as monotherapy or as add-on therapy in RBD in some cases [53,54]. The role of Cannabidiol (CBD) in PD with RBD has also been evaluated in a pilot study. CBD, used in doses ranging from 75 to 300 mg for six consecutive weeks, has shown up to 80% frequency decrease of sleep disturbances [55].","tracks":[{"project":"2_test","denotations":[{"id":"31434341-14638967-7278250","span":{"begin":97,"end":99},"obj":"14638967"},{"id":"31434341-20872929-7278251","span":{"begin":285,"end":287},"obj":"20872929"},{"id":"31434341-19483483-7278252","span":{"begin":435,"end":437},"obj":"19483483"},{"id":"31434341-28366329-7278253","span":{"begin":438,"end":440},"obj":"28366329"},{"id":"31434341-24845114-7278254","span":{"begin":664,"end":666},"obj":"24845114"}],"attributes":[{"subj":"31434341-14638967-7278250","pred":"source","obj":"2_test"},{"subj":"31434341-20872929-7278251","pred":"source","obj":"2_test"},{"subj":"31434341-19483483-7278252","pred":"source","obj":"2_test"},{"subj":"31434341-28366329-7278253","pred":"source","obj":"2_test"},{"subj":"31434341-24845114-7278254","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#93eca1","default":true}]}]}}