PMC:6218602 / 63662-64137 JSONTXT

{"project":"2_test","denotations":[{"id":"30425662-25867121-41865530","span":{"begin":466,"end":469},"obj":"25867121"},{"id":"30425662-23123071-41865530","span":{"begin":466,"end":469},"obj":"23123071"},{"id":"30425662-19759530-41865530","span":{"begin":466,"end":469},"obj":"19759530"},{"id":"30425662-22721950-41865530","span":{"begin":466,"end":469},"obj":"22721950"}],"text":"Surgical modalities that can precisely target particular regions of focal and well-localized dysconnectivity in the brain are currently being tested as a more circuit-specific approach to precision medicine in schizophrenia. Deep brain stimulation (DBS) has been a well-established targeted therapeutic approach that has been used to improve the treatment-resistant symptoms of Parkinson's disease, obsessive-compulsive disorder and treatment refractory depression (199–202)."}