PMC:6019327 / 525870-527170
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/6019327","sourcedb":"PMC","sourceid":"6019327","source_url":"https://www.ncbi.nlm.nih.gov/pmc/6019327","text":"There is a rich history of surgery for AF. Initial procedures were aimed at controlling the ventricular response rate. Later procedures were directed at converting AF to a normal sinus rhythm. Following experimental investigation, the Maze procedure was introduced for the surgical treatment of AF in 1987 by James Cox. This procedure was designed to interrupt macroreentrant circuits, thereby reducing the ability of the atrium to fibrillate. Fortuitously, the surgery also isolated all of the PVs and the posterior LA. In contrast to previous procedures, such as the corridor procedure and LA transection procedures, the Cox-Maze procedure successfully restored both AV synchrony and sinus rhythm and decreased the incidence of late stroke.1287 This effect was attributed to both AF control and amputation of the LAA. The surgery involved creating multiple strategically placed incisions across both the RA and LA. The surgical incisions were placed so that the sinus node could “direct” the propagation of the sinus impulse throughout both atria. It also allowed most of the atrial myocardium to be activated, resulting in preservation of atrial transport function in most patients.1288 The final iteration of this procedure, the Cox-Maze III, became the standard for the surgical treatment of AF.","tracks":[{"project":"2_test","denotations":[{"id":"28506916-10534688-29309711","span":{"begin":742,"end":746},"obj":"10534688"},{"id":"28506916-10534688-29309711","span":{"begin":742,"end":746},"obj":"10534688"},{"id":"28506916-7955267-29309712","span":{"begin":1185,"end":1189},"obj":"7955267"},{"id":"28506916-7955267-29309712","span":{"begin":1185,"end":1189},"obj":"7955267"},{"id":"T33757","span":{"begin":742,"end":746},"obj":"10534688"},{"id":"T45975","span":{"begin":742,"end":746},"obj":"10534688"},{"id":"T31423","span":{"begin":1185,"end":1189},"obj":"7955267"},{"id":"T50900","span":{"begin":1185,"end":1189},"obj":"7955267"},{"id":"T23517","span":{"begin":742,"end":746},"obj":"10534688"},{"id":"T74632","span":{"begin":742,"end":746},"obj":"10534688"},{"id":"T33803","span":{"begin":1185,"end":1189},"obj":"7955267"},{"id":"T74531","span":{"begin":1185,"end":1189},"obj":"7955267"}],"attributes":[{"subj":"28506916-10534688-29309711","pred":"source","obj":"2_test"},{"subj":"28506916-10534688-29309711","pred":"source","obj":"2_test"},{"subj":"28506916-7955267-29309712","pred":"source","obj":"2_test"},{"subj":"28506916-7955267-29309712","pred":"source","obj":"2_test"},{"subj":"T33757","pred":"source","obj":"2_test"},{"subj":"T45975","pred":"source","obj":"2_test"},{"subj":"T31423","pred":"source","obj":"2_test"},{"subj":"T50900","pred":"source","obj":"2_test"},{"subj":"T23517","pred":"source","obj":"2_test"},{"subj":"T74632","pred":"source","obj":"2_test"},{"subj":"T33803","pred":"source","obj":"2_test"},{"subj":"T74531","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#93beec","default":true}]}]}}