PMC:6019327 / 408478-409361
Annnotations
2_test
{"project":"2_test","denotations":[{"id":"28506916-24610797-29309022","span":{"begin":212,"end":215},"obj":"24610797"},{"id":"28506916-24610797-29309022","span":{"begin":212,"end":215},"obj":"24610797"},{"id":"28506916-25281891-29309023","span":{"begin":216,"end":220},"obj":"25281891"},{"id":"28506916-25281891-29309023","span":{"begin":216,"end":220},"obj":"25281891"},{"id":"28506916-26286935-29309024","span":{"begin":221,"end":225},"obj":"26286935"},{"id":"28506916-26286935-29309024","span":{"begin":221,"end":225},"obj":"26286935"},{"id":"28506916-26757058-29309025","span":{"begin":226,"end":230},"obj":"26757058"},{"id":"28506916-26757058-29309025","span":{"begin":226,"end":230},"obj":"26757058"},{"id":"28506916-26976341-29309026","span":{"begin":231,"end":235},"obj":"26976341"},{"id":"28506916-26976341-29309026","span":{"begin":231,"end":235},"obj":"26976341"},{"id":"28506916-26936265-29309027","span":{"begin":236,"end":240},"obj":"26936265"},{"id":"28506916-26936265-29309027","span":{"begin":236,"end":240},"obj":"26936265"},{"id":"28506916-25582875-29309028","span":{"begin":591,"end":595},"obj":"25582875"},{"id":"28506916-25582875-29309028","span":{"begin":591,"end":595},"obj":"25582875"},{"id":"28506916-26936265-29309029","span":{"begin":733,"end":737},"obj":"26936265"},{"id":"28506916-26936265-29309029","span":{"begin":733,"end":737},"obj":"26936265"},{"id":"T86195","span":{"begin":212,"end":215},"obj":"24610797"},{"id":"T64925","span":{"begin":212,"end":215},"obj":"24610797"},{"id":"T45590","span":{"begin":216,"end":220},"obj":"25281891"},{"id":"T98720","span":{"begin":216,"end":220},"obj":"25281891"},{"id":"T28465","span":{"begin":221,"end":225},"obj":"26286935"},{"id":"T87220","span":{"begin":221,"end":225},"obj":"26286935"},{"id":"T1449","span":{"begin":226,"end":230},"obj":"26757058"},{"id":"T20914","span":{"begin":226,"end":230},"obj":"26757058"},{"id":"T73979","span":{"begin":231,"end":235},"obj":"26976341"},{"id":"T97322","span":{"begin":231,"end":235},"obj":"26976341"},{"id":"T2535","span":{"begin":236,"end":240},"obj":"26936265"},{"id":"T95929","span":{"begin":236,"end":240},"obj":"26936265"},{"id":"T43789","span":{"begin":591,"end":595},"obj":"25582875"},{"id":"T2550","span":{"begin":591,"end":595},"obj":"25582875"},{"id":"T69095","span":{"begin":733,"end":737},"obj":"26936265"},{"id":"T25190","span":{"begin":733,"end":737},"obj":"26936265"},{"id":"T35452","span":{"begin":212,"end":215},"obj":"24610797"},{"id":"T84015","span":{"begin":212,"end":215},"obj":"24610797"},{"id":"T23959","span":{"begin":216,"end":220},"obj":"25281891"},{"id":"T85735","span":{"begin":216,"end":220},"obj":"25281891"},{"id":"T97257","span":{"begin":221,"end":225},"obj":"26286935"},{"id":"T38276","span":{"begin":221,"end":225},"obj":"26286935"},{"id":"T16280","span":{"begin":226,"end":230},"obj":"26757058"},{"id":"T42916","span":{"begin":226,"end":230},"obj":"26757058"},{"id":"T14533","span":{"begin":231,"end":235},"obj":"26976341"},{"id":"T73623","span":{"begin":231,"end":235},"obj":"26976341"},{"id":"T14324","span":{"begin":236,"end":240},"obj":"26936265"},{"id":"T82901","span":{"begin":236,"end":240},"obj":"26936265"},{"id":"T98073","span":{"begin":591,"end":595},"obj":"25582875"},{"id":"T33186","span":{"begin":591,"end":595},"obj":"25582875"},{"id":"T96150","span":{"begin":733,"end":737},"obj":"26936265"},{"id":"T50766","span":{"begin":733,"end":737},"obj":"26936265"}],"text":"The role of cryoablation in patients with persistent AF is less well established. To date, data are predominantly derived from relatively small, noncontrolled trials and mostly reflect a single-center experience.486,1073,1074,1075,1076,1077 Overall, cryoablation appears to be associated with a favorable long-term outcome in patients with persistent AF, with arrhythmia-free survival ranging from 56% to 82%. In one non-randomized study, arrhythmia-free survival off AADs was similar when cryoablation was compared with RF ablation at 1-year follow-up after a single procedure (60% vs 50%).1078 Preliminary results from a single-center study demonstrated the feasibility of extra-PV CBA in patients with long-standing persistent AF.1077 Future prospective randomized trials are needed to more precisely define the role of CBA in patients with persistent and long-term persistent AF."}