PMC:5917310 / 17986-18970 JSONTXT

{"project":"TEST0","denotations":[{"id":"29542385-127-133-13677","span":{"begin":310,"end":312},"obj":"[\"11062196\"]"},{"id":"29542385-102-108-13678","span":{"begin":438,"end":440},"obj":"[\"17292768\"]"},{"id":"29542385-179-184-13679","span":{"begin":622,"end":623},"obj":"[\"20483949\"]"},{"id":"29542385-235-241-13680","span":{"begin":980,"end":982},"obj":"[\"26363637\"]"}],"text":"The association between antibiotic consumption and antibiotic-resistant organisms has been widely observed, mainly for other respiratory tract pathogens. For instance, Granizo et al. observed a clear association between previous use of macrolides and β-lactam with erythromycin-resistant pneumococci in Spain [26]. Also, Malotra et al. note that azithromycin and erythromycin use increases resistance of streptococci in healthy carriers [27]. We already knew of the relationship between antibiotic prescribing and bacterial resistance in primary care when antibiotics were prescribed for respiratory or urinary infection [2]. Other studies have also shown an association between previous consumption of antibiotics and S. aureus resistance. For example, in a recent randomised controlled trial, Australian children diagnosed with bronchiectasis assigned to intermittent azithromycin consumption showed higher macrolide-resistant S. aureus carriage than those assigned to placebo [28]."}

{"project":"0_colil","denotations":[{"id":"29542385-11062196-13677","span":{"begin":310,"end":312},"obj":"11062196"},{"id":"29542385-17292768-13678","span":{"begin":438,"end":440},"obj":"17292768"},{"id":"29542385-20483949-13679","span":{"begin":622,"end":623},"obj":"20483949"},{"id":"29542385-26363637-13680","span":{"begin":980,"end":982},"obj":"26363637"}],"text":"The association between antibiotic consumption and antibiotic-resistant organisms has been widely observed, mainly for other respiratory tract pathogens. For instance, Granizo et al. observed a clear association between previous use of macrolides and β-lactam with erythromycin-resistant pneumococci in Spain [26]. Also, Malotra et al. note that azithromycin and erythromycin use increases resistance of streptococci in healthy carriers [27]. We already knew of the relationship between antibiotic prescribing and bacterial resistance in primary care when antibiotics were prescribed for respiratory or urinary infection [2]. Other studies have also shown an association between previous consumption of antibiotics and S. aureus resistance. For example, in a recent randomised controlled trial, Australian children diagnosed with bronchiectasis assigned to intermittent azithromycin consumption showed higher macrolide-resistant S. aureus carriage than those assigned to placebo [28]."}

{"project":"MyTest","denotations":[{"id":"29542385-11062196-29034987","span":{"begin":310,"end":312},"obj":"11062196"},{"id":"29542385-17292768-29034988","span":{"begin":438,"end":440},"obj":"17292768"},{"id":"29542385-20483949-29034989","span":{"begin":622,"end":623},"obj":"20483949"},{"id":"29542385-26363637-29034990","span":{"begin":980,"end":982},"obj":"26363637"}],"namespaces":[{"prefix":"_base","uri":"https://www.uniprot.org/uniprot/testbase"},{"prefix":"UniProtKB","uri":"https://www.uniprot.org/uniprot/"},{"prefix":"uniprot","uri":"https://www.uniprot.org/uniprotkb/"}],"text":"The association between antibiotic consumption and antibiotic-resistant organisms has been widely observed, mainly for other respiratory tract pathogens. For instance, Granizo et al. observed a clear association between previous use of macrolides and β-lactam with erythromycin-resistant pneumococci in Spain [26]. Also, Malotra et al. note that azithromycin and erythromycin use increases resistance of streptococci in healthy carriers [27]. We already knew of the relationship between antibiotic prescribing and bacterial resistance in primary care when antibiotics were prescribed for respiratory or urinary infection [2]. Other studies have also shown an association between previous consumption of antibiotics and S. aureus resistance. For example, in a recent randomised controlled trial, Australian children diagnosed with bronchiectasis assigned to intermittent azithromycin consumption showed higher macrolide-resistant S. aureus carriage than those assigned to placebo [28]."}

{"project":"2_test","denotations":[{"id":"29542385-11062196-29034987","span":{"begin":310,"end":312},"obj":"11062196"},{"id":"29542385-17292768-29034988","span":{"begin":438,"end":440},"obj":"17292768"},{"id":"29542385-20483949-29034989","span":{"begin":622,"end":623},"obj":"20483949"},{"id":"29542385-26363637-29034990","span":{"begin":980,"end":982},"obj":"26363637"}],"text":"The association between antibiotic consumption and antibiotic-resistant organisms has been widely observed, mainly for other respiratory tract pathogens. For instance, Granizo et al. observed a clear association between previous use of macrolides and β-lactam with erythromycin-resistant pneumococci in Spain [26]. Also, Malotra et al. note that azithromycin and erythromycin use increases resistance of streptococci in healthy carriers [27]. We already knew of the relationship between antibiotic prescribing and bacterial resistance in primary care when antibiotics were prescribed for respiratory or urinary infection [2]. Other studies have also shown an association between previous consumption of antibiotics and S. aureus resistance. For example, in a recent randomised controlled trial, Australian children diagnosed with bronchiectasis assigned to intermittent azithromycin consumption showed higher macrolide-resistant S. aureus carriage than those assigned to placebo [28]."}