The association between antibiotic consumption and antibiotic-resistant organisms has been widely observed, mainly for other respiratory tract pathogens. For instance, Granizo et al. observed a clear association between previous use of macrolides and β-lactam with erythromycin-resistant pneumococci in Spain [26]. Also, Malotra et al. note that azithromycin and erythromycin use increases resistance of streptococci in healthy carriers [27]. We already knew of the relationship between antibiotic prescribing and bacterial resistance in primary care when antibiotics were prescribed for respiratory or urinary infection [2]. Other studies have also shown an association between previous consumption of antibiotics and S. aureus resistance. For example, in a recent randomised controlled trial, Australian children diagnosed with bronchiectasis assigned to intermittent azithromycin consumption showed higher macrolide-resistant S. aureus carriage than those assigned to placebo [28].