PMC:549712 / 541-1334
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/549712","sourcedb":"PMC","sourceid":"549712","source_url":"http://www.ncbi.nlm.nih.gov/pmc/549712","text":"Ablation of Ptdsr function in mice causes perinatal lethality, growth retardation and a delay in terminal differentiation of the kidney, intestine, liver and lungs during embryogenesis. Moreover, eye development can be severely disturbed, ranging from defects in retinal differentiation to complete unilateral or bilateral absence of eyes. Ptdsr -/- mice with anophthalmia develop novel lesions, with induction of ectopic retinal-pigmented epithelium in nasal cavities. A comprehensive investigation of apoptotic cell clearance in vivo and in vitro demonstrated that engulfment of apoptotic cells was normal in Ptdsr knockout mice, but Ptdsr-deficient macrophages were impaired in pro- and anti-inflammatory cytokine signaling after stimulation with apoptotic cells or with lipopolysaccharide.","tracks":[{"project":"craft-sa-dev","denotations":[{"id":"T355","span":{"begin":0,"end":8},"obj":"NN"},{"id":"T356","span":{"begin":35,"end":41},"obj":"VBZ"},{"id":"T357","span":{"begin":9,"end":11},"obj":"IN"},{"id":"T358","span":{"begin":12,"end":17},"obj":"NN"},{"id":"T359","span":{"begin":18,"end":26},"obj":"NN"},{"id":"T360","span":{"begin":27,"end":29},"obj":"IN"},{"id":"T361","span":{"begin":30,"end":34},"obj":"NNS"},{"id":"T362","span":{"begin":42,"end":51},"obj":"JJ"},{"id":"T363","span":{"begin":52,"end":61},"obj":"NN"},{"id":"T364","span":{"begin":61,"end":63},"obj":","},{"id":"T365","span":{"begin":63,"end":69},"obj":"NN"},{"id":"T366","span":{"begin":70,"end":81},"obj":"NN"},{"id":"T367","span":{"begin":82,"end":85},"obj":"CC"},{"id":"T368","span":{"begin":86,"end":87},"obj":"DT"},{"id":"T369","span":{"begin":88,"end":93},"obj":"NN"},{"id":"T370","span":{"begin":94,"end":96},"obj":"IN"},{"id":"T371","span":{"begin":97,"end":105},"obj":"JJ"},{"id":"T372","span":{"begin":106,"end":121},"obj":"NN"},{"id":"T373","span":{"begin":122,"end":124},"obj":"IN"},{"id":"T374","span":{"begin":125,"end":128},"obj":"DT"},{"id":"T375","span":{"begin":129,"end":135},"obj":"NN"},{"id":"T376","span":{"begin":135,"end":137},"obj":","},{"id":"T377","span":{"begin":137,"end":146},"obj":"NN"},{"id":"T378","span":{"begin":146,"end":148},"obj":","},{"id":"T379","span":{"begin":148,"end":153},"obj":"NN"},{"id":"T380","span":{"begin":154,"end":157},"obj":"CC"},{"id":"T381","span":{"begin":158,"end":163},"obj":"NNS"},{"id":"T382","span":{"begin":164,"end":170},"obj":"IN"},{"id":"T383","span":{"begin":171,"end":184},"obj":"NN"},{"id":"T384","span":{"begin":184,"end":185},"obj":"."},{"id":"T385","span":{"begin":185,"end":339},"obj":"sentence"},{"id":"T386","span":{"begin":186,"end":194},"obj":"RB"},{"id":"T387","span":{"begin":228,"end":237},"obj":"VBN"},{"id":"T388","span":{"begin":194,"end":196},"obj":","},{"id":"T389","span":{"begin":196,"end":199},"obj":"NN"},{"id":"T390","span":{"begin":200,"end":211},"obj":"NN"},{"id":"T391","span":{"begin":212,"end":215},"obj":"MD"},{"id":"T392","span":{"begin":216,"end":218},"obj":"VB"},{"id":"T393","span":{"begin":219,"end":227},"obj":"RB"},{"id":"T394","span":{"begin":237,"end":239},"obj":","},{"id":"T395","span":{"begin":239,"end":246},"obj":"VBG"},{"id":"T396","span":{"begin":247,"end":251},"obj":"IN"},{"id":"T397","span":{"begin":252,"end":259},"obj":"NNS"},{"id":"T398","span":{"begin":260,"end":262},"obj":"IN"},{"id":"T399","span":{"begin":263,"end":270},"obj":"JJ"},{"id":"T400","span":{"begin":271,"end":286},"obj":"NN"},{"id":"T401","span":{"begin":287,"end":289},"obj":"IN"},{"id":"T402","span":{"begin":290,"end":298},"obj":"JJ"},{"id":"T403","span":{"begin":323,"end":330},"obj":"NN"},{"id":"T404","span":{"begin":299,"end":309},"obj":"JJ"},{"id":"T405","span":{"begin":310,"end":312},"obj":"CC"},{"id":"T406","span":{"begin":313,"end":322},"obj":"JJ"},{"id":"T407","span":{"begin":331,"end":333},"obj":"IN"},{"id":"T408","span":{"begin":334,"end":338},"obj":"NNS"},{"id":"T409","span":{"begin":338,"end":339},"obj":"."},{"id":"T410","span":{"begin":339,"end":469},"obj":"sentence"},{"id":"T411","span":{"begin":340,"end":345},"obj":"NN"},{"id":"T412","span":{"begin":350,"end":354},"obj":"NNS"},{"id":"T413","span":{"begin":346,"end":347},"obj":"SYM"},{"id":"T414","span":{"begin":347,"end":348},"obj":"HYPH"},{"id":"T415","span":{"begin":348,"end":349},"obj":"SYM"},{"id":"T416","span":{"begin":373,"end":380},"obj":"VBP"},{"id":"T417","span":{"begin":355,"end":359},"obj":"IN"},{"id":"T418","span":{"begin":360,"end":372},"obj":"NN"},{"id":"T419","span":{"begin":381,"end":386},"obj":"JJ"},{"id":"T420","span":{"begin":387,"end":394},"obj":"NNS"},{"id":"T421","span":{"begin":394,"end":396},"obj":","},{"id":"T422","span":{"begin":396,"end":400},"obj":"IN"},{"id":"T423","span":{"begin":401,"end":410},"obj":"NN"},{"id":"T424","span":{"begin":411,"end":413},"obj":"IN"},{"id":"T425","span":{"begin":414,"end":421},"obj":"JJ"},{"id":"T426","span":{"begin":440,"end":450},"obj":"NN"},{"id":"T427","span":{"begin":422,"end":429},"obj":"RB"},{"id":"T428","span":{"begin":430,"end":439},"obj":"VBN"},{"id":"T429","span":{"begin":429,"end":430},"obj":"HYPH"},{"id":"T430","span":{"begin":451,"end":453},"obj":"IN"},{"id":"T431","span":{"begin":454,"end":459},"obj":"JJ"},{"id":"T432","span":{"begin":460,"end":468},"obj":"NNS"},{"id":"T433","span":{"begin":468,"end":469},"obj":"."},{"id":"T434","span":{"begin":469,"end":793},"obj":"sentence"},{"id":"T435","span":{"begin":470,"end":471},"obj":"DT"},{"id":"T436","span":{"begin":486,"end":499},"obj":"NN"},{"id":"T437","span":{"begin":472,"end":485},"obj":"JJ"},{"id":"T438","span":{"begin":549,"end":561},"obj":"VBD"},{"id":"T439","span":{"begin":500,"end":502},"obj":"IN"},{"id":"T440","span":{"begin":503,"end":512},"obj":"JJ"},{"id":"T441","span":{"begin":518,"end":527},"obj":"NN"},{"id":"T442","span":{"begin":513,"end":517},"obj":"NN"},{"id":"T443","span":{"begin":528,"end":530},"obj":"FW"},{"id":"T444","span":{"begin":531,"end":535},"obj":"FW"},{"id":"T445","span":{"begin":536,"end":539},"obj":"CC"},{"id":"T446","span":{"begin":540,"end":542},"obj":"FW"},{"id":"T447","span":{"begin":543,"end":548},"obj":"FW"},{"id":"T448","span":{"begin":562,"end":566},"obj":"IN"},{"id":"T449","span":{"begin":597,"end":600},"obj":"VBD"},{"id":"T450","span":{"begin":567,"end":577},"obj":"NN"},{"id":"T451","span":{"begin":578,"end":580},"obj":"IN"},{"id":"T452","span":{"begin":581,"end":590},"obj":"JJ"},{"id":"T453","span":{"begin":591,"end":596},"obj":"NNS"},{"id":"T454","span":{"begin":601,"end":607},"obj":"JJ"},{"id":"T455","span":{"begin":608,"end":610},"obj":"IN"},{"id":"T456","span":{"begin":611,"end":616},"obj":"NN"},{"id":"T457","span":{"begin":626,"end":630},"obj":"NNS"},{"id":"T458","span":{"begin":617,"end":625},"obj":"NN"},{"id":"T459","span":{"begin":630,"end":632},"obj":","},{"id":"T460","span":{"begin":632,"end":635},"obj":"CC"},{"id":"T461","span":{"begin":636,"end":641},"obj":"NN"},{"id":"T462","span":{"begin":642,"end":651},"obj":"JJ"},{"id":"T463","span":{"begin":641,"end":642},"obj":"HYPH"},{"id":"T464","span":{"begin":652,"end":663},"obj":"NNS"},{"id":"T465","span":{"begin":669,"end":677},"obj":"VBN"},{"id":"T466","span":{"begin":664,"end":668},"obj":"VBD"},{"id":"T467","span":{"begin":678,"end":680},"obj":"IN"},{"id":"T468","span":{"begin":681,"end":684},"obj":"AFX"},{"id":"T469","span":{"begin":690,"end":707},"obj":"JJ"},{"id":"T470","span":{"begin":684,"end":685},"obj":"HYPH"},{"id":"T471","span":{"begin":686,"end":689},"obj":"CC"},{"id":"T472","span":{"begin":717,"end":726},"obj":"NN"},{"id":"T473","span":{"begin":708,"end":716},"obj":"NN"},{"id":"T474","span":{"begin":727,"end":732},"obj":"IN"},{"id":"T475","span":{"begin":733,"end":744},"obj":"NN"},{"id":"T476","span":{"begin":745,"end":749},"obj":"IN"},{"id":"T477","span":{"begin":750,"end":759},"obj":"JJ"},{"id":"T478","span":{"begin":760,"end":765},"obj":"NNS"},{"id":"T479","span":{"begin":766,"end":768},"obj":"CC"},{"id":"T480","span":{"begin":769,"end":773},"obj":"IN"},{"id":"T481","span":{"begin":774,"end":792},"obj":"NN"},{"id":"T482","span":{"begin":792,"end":793},"obj":"."}],"relations":[{"id":"R75","pred":"nsubj","subj":"T355","obj":"T356"},{"id":"R76","pred":"prep","subj":"T357","obj":"T355"},{"id":"R77","pred":"compound","subj":"T358","obj":"T359"},{"id":"R78","pred":"pobj","subj":"T359","obj":"T357"},{"id":"R79","pred":"prep","subj":"T360","obj":"T355"},{"id":"R80","pred":"pobj","subj":"T361","obj":"T360"},{"id":"R81","pred":"amod","subj":"T362","obj":"T363"},{"id":"R82","pred":"dobj","subj":"T363","obj":"T356"},{"id":"R83","pred":"punct","subj":"T364","obj":"T363"},{"id":"R84","pred":"compound","subj":"T365","obj":"T366"},{"id":"R85","pred":"conj","subj":"T366","obj":"T363"},{"id":"R86","pred":"cc","subj":"T367","obj":"T366"},{"id":"R87","pred":"det","subj":"T368","obj":"T369"},{"id":"R88","pred":"conj","subj":"T369","obj":"T366"},{"id":"R89","pred":"prep","subj":"T370","obj":"T369"},{"id":"R90","pred":"amod","subj":"T371","obj":"T372"},{"id":"R91","pred":"pobj","subj":"T372","obj":"T370"},{"id":"R92","pred":"prep","subj":"T373","obj":"T372"},{"id":"R93","pred":"det","subj":"T374","obj":"T375"},{"id":"R94","pred":"pobj","subj":"T375","obj":"T373"},{"id":"R95","pred":"punct","subj":"T376","obj":"T375"},{"id":"R96","pred":"conj","subj":"T377","obj":"T375"},{"id":"R97","pred":"punct","subj":"T378","obj":"T377"},{"id":"R98","pred":"conj","subj":"T379","obj":"T377"},{"id":"R99","pred":"cc","subj":"T380","obj":"T379"},{"id":"R100","pred":"conj","subj":"T381","obj":"T379"},{"id":"R101","pred":"prep","subj":"T382","obj":"T369"},{"id":"R102","pred":"pobj","subj":"T383","obj":"T382"},{"id":"R103","pred":"punct","subj":"T384","obj":"T356"},{"id":"R104","pred":"advmod","subj":"T386","obj":"T387"},{"id":"R105","pred":"punct","subj":"T388","obj":"T387"},{"id":"R106","pred":"compound","subj":"T389","obj":"T390"},{"id":"R107","pred":"nsubjpass","subj":"T390","obj":"T387"},{"id":"R108","pred":"aux","subj":"T391","obj":"T387"},{"id":"R109","pred":"auxpass","subj":"T392","obj":"T387"},{"id":"R110","pred":"advmod","subj":"T393","obj":"T387"},{"id":"R111","pred":"punct","subj":"T394","obj":"T387"},{"id":"R112","pred":"advcl","subj":"T395","obj":"T387"},{"id":"R113","pred":"prep","subj":"T396","obj":"T395"},{"id":"R114","pred":"pobj","subj":"T397","obj":"T396"},{"id":"R115","pred":"prep","subj":"T398","obj":"T397"},{"id":"R116","pred":"amod","subj":"T399","obj":"T400"},{"id":"R117","pred":"pobj","subj":"T400","obj":"T398"},{"id":"R118","pred":"prep","subj":"T401","obj":"T396"},{"id":"R119","pred":"amod","subj":"T402","obj":"T403"},{"id":"R121","pred":"amod","subj":"T404","obj":"T403"},{"id":"R122","pred":"cc","subj":"T405","obj":"T404"},{"id":"R123","pred":"conj","subj":"T406","obj":"T404"},{"id":"R124","pred":"prep","subj":"T407","obj":"T403"},{"id":"R125","pred":"pobj","subj":"T408","obj":"T407"},{"id":"R126","pred":"punct","subj":"T409","obj":"T387"},{"id":"R127","pred":"nmod","subj":"T411","obj":"T412"},{"id":"R129","pred":"punct","subj":"T413","obj":"T411"},{"id":"R130","pred":"punct","subj":"T414","obj":"T411"},{"id":"R131","pred":"punct","subj":"T415","obj":"T411"},{"id":"R132","pred":"prep","subj":"T417","obj":"T412"},{"id":"R133","pred":"pobj","subj":"T418","obj":"T417"},{"id":"R134","pred":"amod","subj":"T419","obj":"T420"},{"id":"R135","pred":"dobj","subj":"T420","obj":"T416"},{"id":"R136","pred":"punct","subj":"T421","obj":"T420"},{"id":"R137","pred":"prep","subj":"T422","obj":"T420"},{"id":"R138","pred":"pobj","subj":"T423","obj":"T422"},{"id":"R139","pred":"prep","subj":"T424","obj":"T423"},{"id":"R140","pred":"amod","subj":"T425","obj":"T426"},{"id":"R142","pred":"advmod","subj":"T427","obj":"T428"},{"id":"R143","pred":"amod","subj":"T428","obj":"T426"},{"id":"R144","pred":"punct","subj":"T429","obj":"T428"},{"id":"R145","pred":"prep","subj":"T430","obj":"T423"},{"id":"R146","pred":"amod","subj":"T431","obj":"T432"},{"id":"R147","pred":"pobj","subj":"T432","obj":"T430"},{"id":"R148","pred":"punct","subj":"T433","obj":"T416"},{"id":"R149","pred":"det","subj":"T435","obj":"T436"},{"id":"R150","pred":"nsubj","subj":"T436","obj":"T438"},{"id":"R151","pred":"amod","subj":"T437","obj":"T436"},{"id":"R152","pred":"prep","subj":"T439","obj":"T436"},{"id":"R153","pred":"amod","subj":"T440","obj":"T441"},{"id":"R154","pred":"pobj","subj":"T441","obj":"T439"},{"id":"R155","pred":"compound","subj":"T442","obj":"T441"},{"id":"R156","pred":"advmod","subj":"T443","obj":"T444"},{"id":"R157","pred":"advmod","subj":"T444","obj":"T436"},{"id":"R158","pred":"cc","subj":"T445","obj":"T444"},{"id":"R159","pred":"advmod","subj":"T446","obj":"T447"},{"id":"R160","pred":"conj","subj":"T447","obj":"T444"},{"id":"R161","pred":"mark","subj":"T448","obj":"T449"},{"id":"R162","pred":"ccomp","subj":"T449","obj":"T438"},{"id":"R163","pred":"nsubj","subj":"T450","obj":"T449"},{"id":"R164","pred":"prep","subj":"T451","obj":"T450"},{"id":"R165","pred":"amod","subj":"T452","obj":"T453"},{"id":"R166","pred":"pobj","subj":"T453","obj":"T451"},{"id":"R167","pred":"acomp","subj":"T454","obj":"T449"},{"id":"R168","pred":"prep","subj":"T455","obj":"T449"},{"id":"R169","pred":"compound","subj":"T456","obj":"T457"},{"id":"R170","pred":"pobj","subj":"T457","obj":"T455"},{"id":"R171","pred":"compound","subj":"T458","obj":"T457"},{"id":"R172","pred":"punct","subj":"T459","obj":"T438"},{"id":"R173","pred":"cc","subj":"T460","obj":"T438"},{"id":"R174","pred":"npadvmod","subj":"T461","obj":"T462"},{"id":"R175","pred":"amod","subj":"T462","obj":"T464"},{"id":"R176","pred":"punct","subj":"T463","obj":"T462"},{"id":"R177","pred":"nsubjpass","subj":"T464","obj":"T465"},{"id":"R178","pred":"conj","subj":"T465","obj":"T438"},{"id":"R179","pred":"auxpass","subj":"T466","obj":"T465"},{"id":"R180","pred":"prep","subj":"T467","obj":"T465"},{"id":"R181","pred":"advmod","subj":"T468","obj":"T469"},{"id":"R182","pred":"amod","subj":"T469","obj":"T472"},{"id":"R183","pred":"punct","subj":"T470","obj":"T469"},{"id":"R184","pred":"cc","subj":"T471","obj":"T469"},{"id":"R185","pred":"pobj","subj":"T472","obj":"T467"},{"id":"R186","pred":"compound","subj":"T473","obj":"T472"},{"id":"R187","pred":"prep","subj":"T474","obj":"T465"},{"id":"R188","pred":"pobj","subj":"T475","obj":"T474"},{"id":"R189","pred":"prep","subj":"T476","obj":"T475"},{"id":"R190","pred":"amod","subj":"T477","obj":"T478"},{"id":"R191","pred":"pobj","subj":"T478","obj":"T476"},{"id":"R192","pred":"cc","subj":"T479","obj":"T476"},{"id":"R193","pred":"conj","subj":"T480","obj":"T476"},{"id":"R194","pred":"pobj","subj":"T481","obj":"T480"},{"id":"R195","pred":"punct","subj":"T482","obj":"T465"},{"id":"R120","pred":"pobj","subj":"T403","obj":"T401"},{"id":"R128","pred":"nsubj","subj":"T412","obj":"T416"},{"id":"R141","pred":"pobj","subj":"T426","obj":"T424"}],"attributes":[{"subj":"T355","pred":"source","obj":"craft-sa-dev"},{"subj":"T356","pred":"source","obj":"craft-sa-dev"},{"subj":"T357","pred":"source","obj":"craft-sa-dev"},{"subj":"T358","pred":"source","obj":"craft-sa-dev"},{"subj":"T359","pred":"source","obj":"craft-sa-dev"},{"subj":"T360","pred":"source","obj":"craft-sa-dev"},{"subj":"T361","pred":"source","obj":"craft-sa-dev"},{"subj":"T362","pred":"source","obj":"craft-sa-dev"},{"subj":"T363","pred":"source","obj":"craft-sa-dev"},{"subj":"T364","pred":"source","obj":"craft-sa-dev"},{"subj":"T365","pred":"source","obj":"craft-sa-dev"},{"subj":"T366","pred":"source","obj":"craft-sa-dev"},{"subj":"T367","pred":"source","obj":"craft-sa-dev"},{"subj":"T368","pred":"source","obj":"craft-sa-dev"},{"subj":"T369","pred":"source","obj":"craft-sa-dev"},{"subj":"T370","pred":"source","obj":"craft-sa-dev"},{"subj":"T371","pred":"source","obj":"craft-sa-dev"},{"subj":"T372","pred":"source","obj":"craft-sa-dev"},{"subj":"T373","pred":"source","obj":"craft-sa-dev"},{"subj":"T374","pred":"source","obj":"craft-sa-dev"},{"subj":"T375","pred":"source","obj":"craft-sa-dev"},{"subj":"T376","pred":"source","obj":"craft-sa-dev"},{"subj":"T377","pred":"source","obj":"craft-sa-dev"},{"subj":"T378","pred":"source","obj":"craft-sa-dev"},{"subj":"T379","pred":"source","obj":"craft-sa-dev"},{"subj":"T380","pred":"source","obj":"craft-sa-dev"},{"subj":"T381","pred":"source","obj":"craft-sa-dev"},{"subj":"T382","pred":"source","obj":"craft-sa-dev"},{"subj":"T383","pred":"source","obj":"craft-sa-dev"},{"subj":"T384","pred":"source","obj":"craft-sa-dev"},{"subj":"T385","pred":"source","obj":"craft-sa-dev"},{"subj":"T386","pred":"source","obj":"craft-sa-dev"},{"subj":"T387","pred":"source","obj":"craft-sa-dev"},{"subj":"T388","pred":"source","obj":"craft-sa-dev"},{"subj":"T389","pred":"source","obj":"craft-sa-dev"},{"subj":"T390","pred":"source","obj":"craft-sa-dev"},{"subj":"T391","pred":"source","obj":"craft-sa-dev"},{"subj":"T392","pred":"source","obj":"craft-sa-dev"},{"subj":"T393","pred":"source","obj":"craft-sa-dev"},{"subj":"T394","pred":"source","obj":"craft-sa-dev"},{"subj":"T395","pred":"source","obj":"craft-sa-dev"},{"subj":"T396","pred":"source","obj":"craft-sa-dev"},{"subj":"T397","pred":"source","obj":"craft-sa-dev"},{"subj":"T398","pred":"source","obj":"craft-sa-dev"},{"subj":"T399","pred":"source","obj":"craft-sa-dev"},{"subj":"T400","pred":"source","obj":"craft-sa-dev"},{"subj":"T401","pred":"source","obj":"craft-sa-dev"},{"subj":"T402","pred":"source","obj":"craft-sa-dev"},{"subj":"T403","pred":"source","obj":"craft-sa-dev"},{"subj":"T404","pred":"source","obj":"craft-sa-dev"},{"subj":"T405","pred":"source","obj":"craft-sa-dev"},{"subj":"T406","pred":"source","obj":"craft-sa-dev"},{"subj":"T407","pred":"source","obj":"craft-sa-dev"},{"subj":"T408","pred":"source","obj":"craft-sa-dev"},{"subj":"T409","pred":"source","obj":"craft-sa-dev"},{"subj":"T410","pred":"source","obj":"craft-sa-dev"},{"subj":"T411","pred":"source","obj":"craft-sa-dev"},{"subj":"T412","pred":"source","obj":"craft-sa-dev"},{"subj":"T413","pred":"source","obj":"craft-sa-dev"},{"subj":"T414","pred":"source","obj":"craft-sa-dev"},{"subj":"T415","pred":"source","obj":"craft-sa-dev"},{"subj":"T416","pred":"source","obj":"craft-sa-dev"},{"subj":"T417","pred":"source","obj":"craft-sa-dev"},{"subj":"T418","pred":"source","obj":"craft-sa-dev"},{"subj":"T419","pred":"source","obj":"craft-sa-dev"},{"subj":"T420","pred":"source","obj":"craft-sa-dev"},{"subj":"T421","pred":"source","obj":"craft-sa-dev"},{"subj":"T422","pred":"source","obj":"craft-sa-dev"},{"subj":"T423","pred":"source","obj":"craft-sa-dev"},{"subj":"T424","pred":"source","obj":"craft-sa-dev"},{"subj":"T425","pred":"source","obj":"craft-sa-dev"},{"subj":"T426","pred":"source","obj":"craft-sa-dev"},{"subj":"T427","pred":"source","obj":"craft-sa-dev"},{"subj":"T428","pred":"source","obj":"craft-sa-dev"},{"subj":"T429","pred":"source","obj":"craft-sa-dev"},{"subj":"T430","pred":"source","obj":"craft-sa-dev"},{"subj":"T431","pred":"source","obj":"craft-sa-dev"},{"subj":"T432","pred":"source","obj":"craft-sa-dev"},{"subj":"T433","pred":"source","obj":"craft-sa-dev"},{"subj":"T434","pred":"source","obj":"craft-sa-dev"},{"subj":"T435","pred":"source","obj":"craft-sa-dev"},{"subj":"T436","pred":"source","obj":"craft-sa-dev"},{"subj":"T437","pred":"source","obj":"craft-sa-dev"},{"subj":"T438","pred":"source","obj":"craft-sa-dev"},{"subj":"T439","pred":"source","obj":"craft-sa-dev"},{"subj":"T440","pred":"source","obj":"craft-sa-dev"},{"subj":"T441","pred":"source","obj":"craft-sa-dev"},{"subj":"T442","pred":"source","obj":"craft-sa-dev"},{"subj":"T443","pred":"source","obj":"craft-sa-dev"},{"subj":"T444","pred":"source","obj":"craft-sa-dev"},{"subj":"T445","pred":"source","obj":"craft-sa-dev"},{"subj":"T446","pred":"source","obj":"craft-sa-dev"},{"subj":"T447","pred":"source","obj":"craft-sa-dev"},{"subj":"T448","pred":"source","obj":"craft-sa-dev"},{"subj":"T449","pred":"source","obj":"craft-sa-dev"},{"subj":"T450","pred":"source","obj":"craft-sa-dev"},{"subj":"T451","pred":"source","obj":"craft-sa-dev"},{"subj":"T452","pred":"source","obj":"craft-sa-dev"},{"subj":"T453","pred":"source","obj":"craft-sa-dev"},{"subj":"T454","pred":"source","obj":"craft-sa-dev"},{"subj":"T455","pred":"source","obj":"craft-sa-dev"},{"subj":"T456","pred":"source","obj":"craft-sa-dev"},{"subj":"T457","pred":"source","obj":"craft-sa-dev"},{"subj":"T458","pred":"source","obj":"craft-sa-dev"},{"subj":"T459","pred":"source","obj":"craft-sa-dev"},{"subj":"T460","pred":"source","obj":"craft-sa-dev"},{"subj":"T461","pred":"source","obj":"craft-sa-dev"},{"subj":"T462","pred":"source","obj":"craft-sa-dev"},{"subj":"T463","pred":"source","obj":"craft-sa-dev"},{"subj":"T464","pred":"source","obj":"craft-sa-dev"},{"subj":"T465","pred":"source","obj":"craft-sa-dev"},{"subj":"T466","pred":"source","obj":"craft-sa-dev"},{"subj":"T467","pred":"source","obj":"craft-sa-dev"},{"subj":"T468","pred":"source","obj":"craft-sa-dev"},{"subj":"T469","pred":"source","obj":"craft-sa-dev"},{"subj":"T470","pred":"source","obj":"craft-sa-dev"},{"subj":"T471","pred":"source","obj":"craft-sa-dev"},{"subj":"T472","pred":"source","obj":"craft-sa-dev"},{"subj":"T473","pred":"source","obj":"craft-sa-dev"},{"subj":"T474","pred":"source","obj":"craft-sa-dev"},{"subj":"T475","pred":"source","obj":"craft-sa-dev"},{"subj":"T476","pred":"source","obj":"craft-sa-dev"},{"subj":"T477","pred":"source","obj":"craft-sa-dev"},{"subj":"T478","pred":"source","obj":"craft-sa-dev"},{"subj":"T479","pred":"source","obj":"craft-sa-dev"},{"subj":"T480","pred":"source","obj":"craft-sa-dev"},{"subj":"T481","pred":"source","obj":"craft-sa-dev"},{"subj":"T482","pred":"source","obj":"craft-sa-dev"}]},{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T202","span":{"begin":12,"end":17},"obj":"PR_EXT:000009218"},{"id":"T203","span":{"begin":30,"end":34},"obj":"NCBITaxon:10088"},{"id":"T204","span":{"begin":42,"end":51},"obj":"UBERON:0012101"},{"id":"T205","span":{"begin":46,"end":51},"obj":"GO:0007567"},{"id":"T206","span":{"begin":52,"end":61},"obj":"GO_EXT:fatality_or_lethality"},{"id":"T207","span":{"begin":63,"end":69},"obj":"GO_EXT:biological_growth_entity_or_process"},{"id":"T208","span":{"begin":106,"end":121},"obj":"GO_RO_EXT:developmental_differentiation_process"},{"id":"T209","span":{"begin":129,"end":135},"obj":"UBERON:0002113"},{"id":"T210","span":{"begin":137,"end":146},"obj":"UBERON:0000160"},{"id":"T211","span":{"begin":148,"end":153},"obj":"UBERON:0002107"},{"id":"T212","span":{"begin":158,"end":163},"obj":"UBERON:0002048"},{"id":"T213","span":{"begin":171,"end":184},"obj":"GO:0009790"},{"id":"T214","span":{"begin":196,"end":199},"obj":"UBERON:0000970"},{"id":"T215","span":{"begin":196,"end":211},"obj":"GO:0001654"},{"id":"T216","span":{"begin":263,"end":270},"obj":"UBERON:0000966"},{"id":"T217","span":{"begin":271,"end":286},"obj":"GO_RO_EXT:developmental_differentiation_process"},{"id":"T218","span":{"begin":334,"end":338},"obj":"UBERON:0000970"},{"id":"T219","span":{"begin":340,"end":345},"obj":"PR_EXT:000009218"},{"id":"T220","span":{"begin":346,"end":347},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T221","span":{"begin":348,"end":349},"obj":"SO_EXT:sequence_nullness_or_absence"},{"id":"T222","span":{"begin":350,"end":354},"obj":"NCBITaxon:10088"},{"id":"T223","span":{"begin":422,"end":450},"obj":"UBERON:0001782"},{"id":"T224","span":{"begin":430,"end":439},"obj":"CHEBI_EXT:26130"},{"id":"T225","span":{"begin":454,"end":468},"obj":"UBERON:0001707"},{"id":"T226","span":{"begin":503,"end":517},"obj":"CL:0000445"},{"id":"T227","span":{"begin":503,"end":527},"obj":"GO:0043277"},{"id":"T228","span":{"begin":513,"end":517},"obj":"CL_GO_EXT:cell"},{"id":"T229","span":{"begin":567,"end":596},"obj":"GO:0043652"},{"id":"T230","span":{"begin":581,"end":596},"obj":"CL:0000445"},{"id":"T231","span":{"begin":591,"end":596},"obj":"CL_GO_EXT:cell"},{"id":"T232","span":{"begin":611,"end":616},"obj":"PR_EXT:000009218"},{"id":"T233","span":{"begin":626,"end":630},"obj":"NCBITaxon:10088"},{"id":"T234","span":{"begin":636,"end":641},"obj":"PR_EXT:000009218"},{"id":"T235","span":{"begin":652,"end":663},"obj":"CL:0000235"},{"id":"T236","span":{"begin":695,"end":707},"obj":"GO_PATO_EXT:inflammatory_process_or_quality"},{"id":"T237","span":{"begin":708,"end":716},"obj":"GO_EXT:0005125"},{"id":"T238","span":{"begin":708,"end":726},"obj":"GO:0019221"},{"id":"T239","span":{"begin":750,"end":759},"obj":"GO_PATO_EXT:apoptotic_process_or_quality"},{"id":"T240","span":{"begin":750,"end":765},"obj":"CL:0000445"},{"id":"T241","span":{"begin":760,"end":765},"obj":"CL_GO_EXT:cell"},{"id":"T242","span":{"begin":774,"end":792},"obj":"CHEBI:16412"}],"attributes":[{"subj":"T202","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T203","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T204","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T205","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T206","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T207","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T208","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T209","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T210","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T211","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T212","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T213","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T214","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T215","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T216","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T217","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T218","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T219","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T220","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T221","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T222","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T223","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T224","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T225","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T226","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T227","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T228","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T229","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T230","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T231","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T232","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T233","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T234","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T235","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T236","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T237","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T238","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T239","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T240","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T241","pred":"source","obj":"craft-ca-core-ex-dev"},{"subj":"T242","pred":"source","obj":"craft-ca-core-ex-dev"}]},{"project":"craft-ca-core-dev","denotations":[{"id":"T123","span":{"begin":12,"end":17},"obj":"PR:000009218"},{"id":"T124","span":{"begin":30,"end":34},"obj":"NCBITaxon:10088"},{"id":"T125","span":{"begin":42,"end":51},"obj":"UBERON:0012101"},{"id":"T126","span":{"begin":46,"end":51},"obj":"GO:0007567"},{"id":"T127","span":{"begin":129,"end":135},"obj":"UBERON:0002113"},{"id":"T128","span":{"begin":137,"end":146},"obj":"UBERON:0000160"},{"id":"T129","span":{"begin":148,"end":153},"obj":"UBERON:0002107"},{"id":"T130","span":{"begin":158,"end":163},"obj":"UBERON:0002048"},{"id":"T131","span":{"begin":171,"end":184},"obj":"GO:0009790"},{"id":"T132","span":{"begin":196,"end":199},"obj":"UBERON:0000970"},{"id":"T133","span":{"begin":196,"end":211},"obj":"GO:0001654"},{"id":"T134","span":{"begin":263,"end":270},"obj":"UBERON:0000966"},{"id":"T135","span":{"begin":334,"end":338},"obj":"UBERON:0000970"},{"id":"T136","span":{"begin":340,"end":345},"obj":"PR:000009218"},{"id":"T137","span":{"begin":350,"end":354},"obj":"NCBITaxon:10088"},{"id":"T138","span":{"begin":422,"end":450},"obj":"UBERON:0001782"},{"id":"T139","span":{"begin":430,"end":439},"obj":"CHEBI:26130"},{"id":"T140","span":{"begin":454,"end":468},"obj":"UBERON:0001707"},{"id":"T141","span":{"begin":503,"end":517},"obj":"CL:0000445"},{"id":"T142","span":{"begin":503,"end":527},"obj":"GO:0043277"},{"id":"T143","span":{"begin":567,"end":596},"obj":"GO:0043652"},{"id":"T144","span":{"begin":581,"end":596},"obj":"CL:0000445"},{"id":"T145","span":{"begin":611,"end":616},"obj":"PR:000009218"},{"id":"T146","span":{"begin":626,"end":630},"obj":"NCBITaxon:10088"},{"id":"T147","span":{"begin":636,"end":641},"obj":"PR:000009218"},{"id":"T148","span":{"begin":652,"end":663},"obj":"CL:0000235"},{"id":"T149","span":{"begin":708,"end":726},"obj":"GO:0019221"},{"id":"T150","span":{"begin":750,"end":765},"obj":"CL:0000445"},{"id":"T151","span":{"begin":774,"end":792},"obj":"CHEBI:16412"}],"attributes":[{"subj":"T123","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T124","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T125","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T126","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T127","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T128","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T129","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T130","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T131","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T132","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T133","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T134","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T135","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T136","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T137","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T138","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T139","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T140","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T141","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T142","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T143","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T144","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T145","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T146","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T147","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T148","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T149","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T150","pred":"source","obj":"craft-ca-core-dev"},{"subj":"T151","pred":"source","obj":"craft-ca-core-dev"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"craft-sa-dev","color":"#93ec9c","default":true},{"id":"craft-ca-core-ex-dev","color":"#ec93a3"},{"id":"craft-ca-core-dev","color":"#93bdec"}]}]}}