Id |
Subject |
Object |
Predicate |
Lexical cue |
T355 |
0-8 |
NN |
denotes |
Ablation |
T356 |
35-41 |
VBZ |
denotes |
causes |
T357 |
9-11 |
IN |
denotes |
of |
T358 |
12-17 |
NN |
denotes |
Ptdsr |
T359 |
18-26 |
NN |
denotes |
function |
T360 |
27-29 |
IN |
denotes |
in |
T361 |
30-34 |
NNS |
denotes |
mice |
T362 |
42-51 |
JJ |
denotes |
perinatal |
T363 |
52-61 |
NN |
denotes |
lethality |
T364 |
61-63 |
, |
denotes |
, |
T365 |
63-69 |
NN |
denotes |
growth |
T366 |
70-81 |
NN |
denotes |
retardation |
T367 |
82-85 |
CC |
denotes |
and |
T368 |
86-87 |
DT |
denotes |
a |
T369 |
88-93 |
NN |
denotes |
delay |
T370 |
94-96 |
IN |
denotes |
in |
T371 |
97-105 |
JJ |
denotes |
terminal |
T372 |
106-121 |
NN |
denotes |
differentiation |
T373 |
122-124 |
IN |
denotes |
of |
T374 |
125-128 |
DT |
denotes |
the |
T375 |
129-135 |
NN |
denotes |
kidney |
T376 |
135-137 |
, |
denotes |
, |
T377 |
137-146 |
NN |
denotes |
intestine |
T378 |
146-148 |
, |
denotes |
, |
T379 |
148-153 |
NN |
denotes |
liver |
T380 |
154-157 |
CC |
denotes |
and |
T381 |
158-163 |
NNS |
denotes |
lungs |
T382 |
164-170 |
IN |
denotes |
during |
T383 |
171-184 |
NN |
denotes |
embryogenesis |
T384 |
184-185 |
. |
denotes |
. |
T385 |
185-339 |
sentence |
denotes |
Moreover, eye development can be severely disturbed, ranging from defects in retinal differentiation to complete unilateral or bilateral absence of eyes. |
T386 |
186-194 |
RB |
denotes |
Moreover |
T387 |
228-237 |
VBN |
denotes |
disturbed |
T388 |
194-196 |
, |
denotes |
, |
T389 |
196-199 |
NN |
denotes |
eye |
T390 |
200-211 |
NN |
denotes |
development |
T391 |
212-215 |
MD |
denotes |
can |
T392 |
216-218 |
VB |
denotes |
be |
T393 |
219-227 |
RB |
denotes |
severely |
T394 |
237-239 |
, |
denotes |
, |
T395 |
239-246 |
VBG |
denotes |
ranging |
T396 |
247-251 |
IN |
denotes |
from |
T397 |
252-259 |
NNS |
denotes |
defects |
T398 |
260-262 |
IN |
denotes |
in |
T399 |
263-270 |
JJ |
denotes |
retinal |
T400 |
271-286 |
NN |
denotes |
differentiation |
T401 |
287-289 |
IN |
denotes |
to |
T402 |
290-298 |
JJ |
denotes |
complete |
T403 |
323-330 |
NN |
denotes |
absence |
T404 |
299-309 |
JJ |
denotes |
unilateral |
T405 |
310-312 |
CC |
denotes |
or |
T406 |
313-322 |
JJ |
denotes |
bilateral |
T407 |
331-333 |
IN |
denotes |
of |
T408 |
334-338 |
NNS |
denotes |
eyes |
T409 |
338-339 |
. |
denotes |
. |
T410 |
339-469 |
sentence |
denotes |
Ptdsr -/- mice with anophthalmia develop novel lesions, with induction of ectopic retinal-pigmented epithelium in nasal cavities. |
T411 |
340-345 |
NN |
denotes |
Ptdsr |
T412 |
350-354 |
NNS |
denotes |
mice |
T413 |
346-347 |
SYM |
denotes |
- |
T414 |
347-348 |
HYPH |
denotes |
/ |
T415 |
348-349 |
SYM |
denotes |
- |
T416 |
373-380 |
VBP |
denotes |
develop |
T417 |
355-359 |
IN |
denotes |
with |
T418 |
360-372 |
NN |
denotes |
anophthalmia |
T419 |
381-386 |
JJ |
denotes |
novel |
T420 |
387-394 |
NNS |
denotes |
lesions |
T421 |
394-396 |
, |
denotes |
, |
T422 |
396-400 |
IN |
denotes |
with |
T423 |
401-410 |
NN |
denotes |
induction |
T424 |
411-413 |
IN |
denotes |
of |
T425 |
414-421 |
JJ |
denotes |
ectopic |
T426 |
440-450 |
NN |
denotes |
epithelium |
T427 |
422-429 |
RB |
denotes |
retinal |
T428 |
430-439 |
VBN |
denotes |
pigmented |
T429 |
429-430 |
HYPH |
denotes |
- |
T430 |
451-453 |
IN |
denotes |
in |
T431 |
454-459 |
JJ |
denotes |
nasal |
T432 |
460-468 |
NNS |
denotes |
cavities |
T433 |
468-469 |
. |
denotes |
. |
T434 |
469-793 |
sentence |
denotes |
A comprehensive investigation of apoptotic cell clearance in vivo and in vitro demonstrated that engulfment of apoptotic cells was normal in Ptdsr knockout mice, but Ptdsr-deficient macrophages were impaired in pro- and anti-inflammatory cytokine signaling after stimulation with apoptotic cells or with lipopolysaccharide. |
T435 |
470-471 |
DT |
denotes |
A |
T436 |
486-499 |
NN |
denotes |
investigation |
T437 |
472-485 |
JJ |
denotes |
comprehensive |
T438 |
549-561 |
VBD |
denotes |
demonstrated |
T439 |
500-502 |
IN |
denotes |
of |
T440 |
503-512 |
JJ |
denotes |
apoptotic |
T441 |
518-527 |
NN |
denotes |
clearance |
T442 |
513-517 |
NN |
denotes |
cell |
T443 |
528-530 |
FW |
denotes |
in |
T444 |
531-535 |
FW |
denotes |
vivo |
T445 |
536-539 |
CC |
denotes |
and |
T446 |
540-542 |
FW |
denotes |
in |
T447 |
543-548 |
FW |
denotes |
vitro |
T448 |
562-566 |
IN |
denotes |
that |
T449 |
597-600 |
VBD |
denotes |
was |
T450 |
567-577 |
NN |
denotes |
engulfment |
T451 |
578-580 |
IN |
denotes |
of |
T452 |
581-590 |
JJ |
denotes |
apoptotic |
T453 |
591-596 |
NNS |
denotes |
cells |
T454 |
601-607 |
JJ |
denotes |
normal |
T455 |
608-610 |
IN |
denotes |
in |
T456 |
611-616 |
NN |
denotes |
Ptdsr |
T457 |
626-630 |
NNS |
denotes |
mice |
T458 |
617-625 |
NN |
denotes |
knockout |
T459 |
630-632 |
, |
denotes |
, |
T460 |
632-635 |
CC |
denotes |
but |
T461 |
636-641 |
NN |
denotes |
Ptdsr |
T462 |
642-651 |
JJ |
denotes |
deficient |
T463 |
641-642 |
HYPH |
denotes |
- |
T464 |
652-663 |
NNS |
denotes |
macrophages |
T465 |
669-677 |
VBN |
denotes |
impaired |
T466 |
664-668 |
VBD |
denotes |
were |
T467 |
678-680 |
IN |
denotes |
in |
T468 |
681-684 |
AFX |
denotes |
pro |
T469 |
690-707 |
JJ |
denotes |
anti-inflammatory |
T470 |
684-685 |
HYPH |
denotes |
- |
T471 |
686-689 |
CC |
denotes |
and |
T472 |
717-726 |
NN |
denotes |
signaling |
T473 |
708-716 |
NN |
denotes |
cytokine |
T474 |
727-732 |
IN |
denotes |
after |
T475 |
733-744 |
NN |
denotes |
stimulation |
T476 |
745-749 |
IN |
denotes |
with |
T477 |
750-759 |
JJ |
denotes |
apoptotic |
T478 |
760-765 |
NNS |
denotes |
cells |
T479 |
766-768 |
CC |
denotes |
or |
T480 |
769-773 |
IN |
denotes |
with |
T481 |
774-792 |
NN |
denotes |
lipopolysaccharide |
T482 |
792-793 |
. |
denotes |
. |
R75 |
T355 |
T356 |
nsubj |
Ablation,causes |
R76 |
T357 |
T355 |
prep |
of,Ablation |
R77 |
T358 |
T359 |
compound |
Ptdsr,function |
R78 |
T359 |
T357 |
pobj |
function,of |
R79 |
T360 |
T355 |
prep |
in,Ablation |
R80 |
T361 |
T360 |
pobj |
mice,in |
R81 |
T362 |
T363 |
amod |
perinatal,lethality |
R82 |
T363 |
T356 |
dobj |
lethality,causes |
R83 |
T364 |
T363 |
punct |
", ",lethality |
R84 |
T365 |
T366 |
compound |
growth,retardation |
R85 |
T366 |
T363 |
conj |
retardation,lethality |
R86 |
T367 |
T366 |
cc |
and,retardation |
R87 |
T368 |
T369 |
det |
a,delay |
R88 |
T369 |
T366 |
conj |
delay,retardation |
R89 |
T370 |
T369 |
prep |
in,delay |
R90 |
T371 |
T372 |
amod |
terminal,differentiation |
R91 |
T372 |
T370 |
pobj |
differentiation,in |
R92 |
T373 |
T372 |
prep |
of,differentiation |
R93 |
T374 |
T375 |
det |
the,kidney |
R94 |
T375 |
T373 |
pobj |
kidney,of |
R95 |
T376 |
T375 |
punct |
", ",kidney |
R96 |
T377 |
T375 |
conj |
intestine,kidney |
R97 |
T378 |
T377 |
punct |
", ",intestine |
R98 |
T379 |
T377 |
conj |
liver,intestine |
R99 |
T380 |
T379 |
cc |
and,liver |
R100 |
T381 |
T379 |
conj |
lungs,liver |
R101 |
T382 |
T369 |
prep |
during,delay |
R102 |
T383 |
T382 |
pobj |
embryogenesis,during |
R103 |
T384 |
T356 |
punct |
.,causes |
R104 |
T386 |
T387 |
advmod |
Moreover,disturbed |
R105 |
T388 |
T387 |
punct |
", ",disturbed |
R106 |
T389 |
T390 |
compound |
eye,development |
R107 |
T390 |
T387 |
nsubjpass |
development,disturbed |
R108 |
T391 |
T387 |
aux |
can,disturbed |
R109 |
T392 |
T387 |
auxpass |
be,disturbed |
R110 |
T393 |
T387 |
advmod |
severely,disturbed |
R111 |
T394 |
T387 |
punct |
", ",disturbed |
R112 |
T395 |
T387 |
advcl |
ranging,disturbed |
R113 |
T396 |
T395 |
prep |
from,ranging |
R114 |
T397 |
T396 |
pobj |
defects,from |
R115 |
T398 |
T397 |
prep |
in,defects |
R116 |
T399 |
T400 |
amod |
retinal,differentiation |
R117 |
T400 |
T398 |
pobj |
differentiation,in |
R118 |
T401 |
T396 |
prep |
to,from |
R119 |
T402 |
T403 |
amod |
complete,absence |
R121 |
T404 |
T403 |
amod |
unilateral,absence |
R122 |
T405 |
T404 |
cc |
or,unilateral |
R123 |
T406 |
T404 |
conj |
bilateral,unilateral |
R124 |
T407 |
T403 |
prep |
of,absence |
R125 |
T408 |
T407 |
pobj |
eyes,of |
R126 |
T409 |
T387 |
punct |
.,disturbed |
R127 |
T411 |
T412 |
nmod |
Ptdsr,mice |
R129 |
T413 |
T411 |
punct |
-,Ptdsr |
R130 |
T414 |
T411 |
punct |
/,Ptdsr |
R131 |
T415 |
T411 |
punct |
-,Ptdsr |
R132 |
T417 |
T412 |
prep |
with,mice |
R133 |
T418 |
T417 |
pobj |
anophthalmia,with |
R134 |
T419 |
T420 |
amod |
novel,lesions |
R135 |
T420 |
T416 |
dobj |
lesions,develop |
R136 |
T421 |
T420 |
punct |
", ",lesions |
R137 |
T422 |
T420 |
prep |
with,lesions |
R138 |
T423 |
T422 |
pobj |
induction,with |
R139 |
T424 |
T423 |
prep |
of,induction |
R140 |
T425 |
T426 |
amod |
ectopic,epithelium |
R142 |
T427 |
T428 |
advmod |
retinal,pigmented |
R143 |
T428 |
T426 |
amod |
pigmented,epithelium |
R144 |
T429 |
T428 |
punct |
-,pigmented |
R145 |
T430 |
T423 |
prep |
in,induction |
R146 |
T431 |
T432 |
amod |
nasal,cavities |
R147 |
T432 |
T430 |
pobj |
cavities,in |
R148 |
T433 |
T416 |
punct |
.,develop |
R149 |
T435 |
T436 |
det |
A,investigation |
R150 |
T436 |
T438 |
nsubj |
investigation,demonstrated |
R151 |
T437 |
T436 |
amod |
comprehensive,investigation |
R152 |
T439 |
T436 |
prep |
of,investigation |
R153 |
T440 |
T441 |
amod |
apoptotic,clearance |
R154 |
T441 |
T439 |
pobj |
clearance,of |
R155 |
T442 |
T441 |
compound |
cell,clearance |
R156 |
T443 |
T444 |
advmod |
in,vivo |
R157 |
T444 |
T436 |
advmod |
vivo,investigation |
R158 |
T445 |
T444 |
cc |
and,vivo |
R159 |
T446 |
T447 |
advmod |
in,vitro |
R160 |
T447 |
T444 |
conj |
vitro,vivo |
R161 |
T448 |
T449 |
mark |
that,was |
R162 |
T449 |
T438 |
ccomp |
was,demonstrated |
R163 |
T450 |
T449 |
nsubj |
engulfment,was |
R164 |
T451 |
T450 |
prep |
of,engulfment |
R165 |
T452 |
T453 |
amod |
apoptotic,cells |
R166 |
T453 |
T451 |
pobj |
cells,of |
R167 |
T454 |
T449 |
acomp |
normal,was |
R168 |
T455 |
T449 |
prep |
in,was |
R169 |
T456 |
T457 |
compound |
Ptdsr,mice |
R170 |
T457 |
T455 |
pobj |
mice,in |
R171 |
T458 |
T457 |
compound |
knockout,mice |
R172 |
T459 |
T438 |
punct |
", ",demonstrated |
R173 |
T460 |
T438 |
cc |
but,demonstrated |
R174 |
T461 |
T462 |
npadvmod |
Ptdsr,deficient |
R175 |
T462 |
T464 |
amod |
deficient,macrophages |
R176 |
T463 |
T462 |
punct |
-,deficient |
R177 |
T464 |
T465 |
nsubjpass |
macrophages,impaired |
R178 |
T465 |
T438 |
conj |
impaired,demonstrated |
R179 |
T466 |
T465 |
auxpass |
were,impaired |
R180 |
T467 |
T465 |
prep |
in,impaired |
R181 |
T468 |
T469 |
advmod |
pro,anti-inflammatory |
R182 |
T469 |
T472 |
amod |
anti-inflammatory,signaling |
R183 |
T470 |
T469 |
punct |
-,anti-inflammatory |
R184 |
T471 |
T469 |
cc |
and,anti-inflammatory |
R185 |
T472 |
T467 |
pobj |
signaling,in |
R186 |
T473 |
T472 |
compound |
cytokine,signaling |
R187 |
T474 |
T465 |
prep |
after,impaired |
R188 |
T475 |
T474 |
pobj |
stimulation,after |
R189 |
T476 |
T475 |
prep |
with,stimulation |
R190 |
T477 |
T478 |
amod |
apoptotic,cells |
R191 |
T478 |
T476 |
pobj |
cells,with |
R192 |
T479 |
T476 |
cc |
or,with |
R193 |
T480 |
T476 |
conj |
with,with |
R194 |
T481 |
T480 |
pobj |
lipopolysaccharide,with |
R195 |
T482 |
T465 |
punct |
.,impaired |
R120 |
T403 |
T401 |
pobj |
absence,to |
R128 |
T412 |
T416 |
nsubj |
mice,develop |
R141 |
T426 |
T424 |
pobj |
epithelium,of |