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PMC:549712 / 26836-27854 JSONTXT

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craft-sa-dev

Id Subject Object Predicate Lexical cue
T8356 0-2 IN denotes In
T8357 89-97 VBN denotes proposed
T8358 3-11 NN denotes addition
T8359 12-14 IN denotes to
T8360 15-18 PRP$ denotes its
T8361 29-39 NN denotes importance
T8362 19-28 JJ denotes suggested
T8363 40-43 IN denotes for
T8364 44-56 NN denotes phagocytosis
T8365 57-59 IN denotes of
T8366 60-69 JJ denotes apoptotic
T8367 70-75 NNS denotes cells
T8368 75-77 , denotes ,
T8369 77-79 PRP denotes it
T8370 80-83 VBZ denotes has
T8371 84-88 VBN denotes been
T8372 98-102 IN denotes that
T8373 109-116 VBZ denotes fulfils
T8374 103-108 NN denotes Ptdsr
T8375 117-118 DT denotes a
T8376 134-138 NN denotes role
T8377 119-125 JJ denotes second
T8378 126-133 JJ denotes crucial
T8379 139-141 IN denotes in
T8380 142-152 VBG denotes regulating
T8381 153-156 CC denotes and
T8382 157-168 VBG denotes maintaining
T8383 169-170 DT denotes a
T8384 188-199 NN denotes environment
T8385 171-187 JJ denotes non-inflammatory
T8386 200-204 IN denotes upon
T8387 205-208 DT denotes the
T8388 209-220 NN denotes recognition
T8389 221-223 IN denotes of
T8390 224-233 JJ denotes apoptotic
T8391 234-239 NNS denotes cells
T8392 240-242 IN denotes by
T8393 243-254 NNS denotes macrophages
T8394 255-256 -LRB- denotes [
T8395 256-258 CD denotes 26
T8396 258-259 -RRB- denotes ]
T8397 259-260 . denotes .
T8398 260-395 sentence denotes We therefore tested whether Ptdsr -/- macrophages were able to release anti-inflammatory cytokines after ingestion of apoptotic cells.
T8399 261-263 PRP denotes We
T8400 274-280 VBD denotes tested
T8401 264-273 RB denotes therefore
T8402 281-288 IN denotes whether
T8403 311-315 VBD denotes were
T8404 289-294 NN denotes Ptdsr
T8405 299-310 NNS denotes macrophages
T8406 295-296 SYM denotes -
T8407 296-297 HYPH denotes /
T8408 297-298 SYM denotes -
T8409 316-320 JJ denotes able
T8410 321-323 TO denotes to
T8411 324-331 VB denotes release
T8412 332-349 JJ denotes anti-inflammatory
T8413 350-359 NNS denotes cytokines
T8414 360-365 IN denotes after
T8415 366-375 NN denotes ingestion
T8416 376-378 IN denotes of
T8417 379-388 JJ denotes apoptotic
T8418 389-394 NNS denotes cells
T8419 394-395 . denotes .
T8420 395-557 sentence denotes We examined levels of TGF-β1 and interleukin-10 (IL-10) after stimulation of FLDMs with lipopolysaccharide (LPS), with and without co-culture of apoptotic cells.
T8421 396-398 PRP denotes We
T8422 399-407 VBD denotes examined
T8423 408-414 NNS denotes levels
T8424 415-417 IN denotes of
T8425 418-421 NN denotes TGF
T8426 422-424 NN denotes β1
T8427 421-422 HYPH denotes -
T8428 425-428 CC denotes and
T8429 429-440 NN denotes interleukin
T8430 440-441 HYPH denotes -
T8431 441-443 CD denotes 10
T8432 444-445 -LRB- denotes (
T8433 445-447 NN denotes IL
T8434 447-448 HYPH denotes -
T8435 448-450 CD denotes 10
T8436 450-451 -RRB- denotes )
T8437 452-457 IN denotes after
T8438 458-469 NN denotes stimulation
T8439 470-472 IN denotes of
T8440 473-478 NNS denotes FLDMs
T8441 479-483 IN denotes with
T8442 484-502 NN denotes lipopolysaccharide
T8443 503-504 -LRB- denotes (
T8444 504-507 NN denotes LPS
T8445 507-508 -RRB- denotes )
T8446 508-510 , denotes ,
T8447 510-514 IN denotes with
T8448 515-518 CC denotes and
T8449 519-526 IN denotes without
T8450 527-537 NN denotes co-culture
T8451 538-540 IN denotes of
T8452 541-550 JJ denotes apoptotic
T8453 551-556 NNS denotes cells
T8454 556-557 . denotes .
T8455 557-820 sentence denotes Quantification of TGF-β1 and IL-10 levels after 22 hours of culture demonstrated that Ptdsr -/- macrophages were able to secrete these anti-inflammatory cytokines upon ingestion of apoptotic cells, although at a slightly lower level than wild-type (Figure 8a,b).
T8456 558-572 NN denotes Quantification
T8457 626-638 VBD denotes demonstrated
T8458 573-575 IN denotes of
T8459 576-579 NN denotes TGF
T8460 580-582 NN denotes β1
T8461 579-580 HYPH denotes -
T8462 593-599 NNS denotes levels
T8463 583-586 CC denotes and
T8464 587-589 NN denotes IL
T8465 589-590 HYPH denotes -
T8466 590-592 CD denotes 10
T8467 600-605 IN denotes after
T8468 606-608 CD denotes 22
T8469 609-614 NNS denotes hours
T8470 615-617 IN denotes of
T8471 618-625 NN denotes culture
T8472 639-643 IN denotes that
T8473 666-670 VBD denotes were
T8474 644-649 NN denotes Ptdsr
T8475 654-665 NNS denotes macrophages
T8476 650-651 SYM denotes -
T8477 651-652 HYPH denotes /
T8478 652-653 SYM denotes -
T8479 671-675 JJ denotes able
T8480 676-678 TO denotes to
T8481 679-686 VB denotes secrete
T8482 687-692 DT denotes these
T8483 711-720 NNS denotes cytokines
T8484 693-710 JJ denotes anti-inflammatory
T8485 721-725 IN denotes upon
T8486 726-735 NN denotes ingestion
T8487 736-738 IN denotes of
T8488 739-748 JJ denotes apoptotic
T8489 749-754 NNS denotes cells
T8490 754-756 , denotes ,
T8491 756-764 IN denotes although
T8492 765-767 IN denotes at
T8493 768-769 DT denotes a
T8494 785-790 NN denotes level
T8495 770-778 RB denotes slightly
T8496 779-784 JJR denotes lower
T8497 791-795 IN denotes than
T8498 796-800 JJ denotes wild
T8499 801-805 NN denotes type
T8500 800-801 HYPH denotes -
T8501 806-807 -LRB- denotes (
T8502 817-818 NN denotes b
T8503 807-813 NN denotes Figure
T8504 814-816 NN denotes 8a
T8505 816-817 , denotes ,
T8506 818-819 -RRB- denotes )
T8507 819-820 . denotes .
T8508 820-1018 sentence denotes This indicates that ablation of Ptdsr function does not compromise in general the ability of macrophages to release immune-suppressive cytokines after recognition and engulfment of apoptotic cells.
T8509 821-825 DT denotes This
T8510 826-835 VBZ denotes indicates
T8511 836-840 IN denotes that
T8512 877-887 VB denotes compromise
T8513 841-849 NN denotes ablation
T8514 850-852 IN denotes of
T8515 853-858 NN denotes Ptdsr
T8516 859-867 NN denotes function
T8517 868-872 VBZ denotes does
T8518 873-876 RB denotes not
T8519 888-890 IN denotes in
T8520 891-898 JJ denotes general
T8521 899-902 DT denotes the
T8522 903-910 NN denotes ability
T8523 911-913 IN denotes of
T8524 914-925 NNS denotes macrophages
T8525 926-928 TO denotes to
T8526 929-936 VB denotes release
T8527 937-943 NN denotes immune
T8528 944-955 JJ denotes suppressive
T8529 943-944 HYPH denotes -
T8530 956-965 NNS denotes cytokines
T8531 966-971 IN denotes after
T8532 972-983 NN denotes recognition
T8533 984-987 CC denotes and
T8534 988-998 NN denotes engulfment
T8535 999-1001 IN denotes of
T8536 1002-1011 JJ denotes apoptotic
T8537 1012-1017 NNS denotes cells
T8538 1017-1018 . denotes .
R4754 T8356 T8357 prep In,proposed
R4755 T8358 T8356 pobj addition,In
R4756 T8359 T8358 prep to,addition
R4757 T8360 T8361 poss its,importance
R4758 T8361 T8359 pobj importance,to
R4759 T8362 T8361 amod suggested,importance
R4760 T8363 T8361 prep for,importance
R4761 T8364 T8363 pobj phagocytosis,for
R4762 T8365 T8364 prep of,phagocytosis
R4763 T8366 T8367 amod apoptotic,cells
R4764 T8367 T8365 pobj cells,of
R4765 T8368 T8357 punct ", ",proposed
R4766 T8369 T8357 nsubjpass it,proposed
R4767 T8370 T8357 aux has,proposed
R4768 T8371 T8357 auxpass been,proposed
R4769 T8372 T8373 mark that,fulfils
R4770 T8373 T8357 ccomp fulfils,proposed
R4771 T8374 T8373 nsubj Ptdsr,fulfils
R4772 T8375 T8376 det a,role
R4773 T8376 T8373 dobj role,fulfils
R4774 T8377 T8376 amod second,role
R4775 T8378 T8376 amod crucial,role
R4776 T8379 T8376 prep in,role
R4777 T8380 T8379 pcomp regulating,in
R4778 T8381 T8380 cc and,regulating
R4779 T8382 T8380 conj maintaining,regulating
R4780 T8383 T8384 det a,environment
R4781 T8384 T8382 dobj environment,maintaining
R4782 T8385 T8384 amod non-inflammatory,environment
R4783 T8386 T8382 prep upon,maintaining
R4784 T8387 T8388 det the,recognition
R4785 T8388 T8386 pobj recognition,upon
R4786 T8389 T8388 prep of,recognition
R4787 T8390 T8391 amod apoptotic,cells
R4788 T8391 T8389 pobj cells,of
R4789 T8392 T8388 prep by,recognition
R4790 T8393 T8392 pobj macrophages,by
R4791 T8394 T8395 punct [,26
R4792 T8395 T8357 parataxis 26,proposed
R4793 T8396 T8395 punct ],26
R4794 T8397 T8357 punct .,proposed
R4795 T8399 T8400 nsubj We,tested
R4796 T8401 T8400 advmod therefore,tested
R4797 T8402 T8403 mark whether,were
R4798 T8403 T8400 ccomp were,tested
R4799 T8404 T8405 nmod Ptdsr,macrophages
R4800 T8405 T8403 nsubj macrophages,were
R4801 T8406 T8404 punct -,Ptdsr
R4802 T8407 T8404 punct /,Ptdsr
R4803 T8408 T8404 punct -,Ptdsr
R4804 T8409 T8403 acomp able,were
R4805 T8410 T8411 aux to,release
R4806 T8411 T8409 xcomp release,able
R4807 T8412 T8413 amod anti-inflammatory,cytokines
R4808 T8413 T8411 dobj cytokines,release
R4809 T8414 T8411 prep after,release
R4810 T8415 T8414 pobj ingestion,after
R4811 T8416 T8415 prep of,ingestion
R4812 T8417 T8418 amod apoptotic,cells
R4813 T8418 T8416 pobj cells,of
R4814 T8419 T8400 punct .,tested
R4815 T8421 T8422 nsubj We,examined
R4816 T8423 T8422 dobj levels,examined
R4817 T8424 T8423 prep of,levels
R4818 T8425 T8426 compound TGF,β1
R4819 T8426 T8424 pobj β1,of
R4820 T8427 T8426 punct -,β1
R4821 T8428 T8426 cc and,β1
R4822 T8429 T8426 conj interleukin,β1
R4823 T8430 T8429 punct -,interleukin
R4824 T8431 T8429 nummod 10,interleukin
R4825 T8432 T8433 punct (,IL
R4826 T8433 T8429 parataxis IL,interleukin
R4827 T8434 T8433 punct -,IL
R4828 T8435 T8433 nummod 10,IL
R4829 T8436 T8433 punct ),IL
R4830 T8437 T8422 prep after,examined
R4831 T8438 T8437 pobj stimulation,after
R4832 T8439 T8438 prep of,stimulation
R4833 T8440 T8439 pobj FLDMs,of
R4834 T8441 T8438 prep with,stimulation
R4835 T8442 T8441 pobj lipopolysaccharide,with
R4836 T8443 T8442 punct (,lipopolysaccharide
R4837 T8444 T8442 appos LPS,lipopolysaccharide
R4838 T8445 T8422 punct ),examined
R4839 T8446 T8422 punct ", ",examined
R4840 T8447 T8422 prep with,examined
R4841 T8448 T8447 cc and,with
R4842 T8449 T8447 conj without,with
R4843 T8450 T8449 pobj co-culture,without
R4844 T8451 T8450 prep of,co-culture
R4845 T8452 T8453 amod apoptotic,cells
R4846 T8453 T8451 pobj cells,of
R4847 T8454 T8422 punct .,examined
R4848 T8456 T8457 nsubj Quantification,demonstrated
R4849 T8458 T8456 prep of,Quantification
R4850 T8459 T8460 nmod TGF,β1
R4851 T8460 T8462 nmod β1,levels
R4852 T8461 T8460 punct -,β1
R4853 T8462 T8458 pobj levels,of
R4854 T8463 T8460 cc and,β1
R4855 T8464 T8460 conj IL,β1
R4856 T8465 T8464 punct -,IL
R4857 T8466 T8464 nummod 10,IL
R4858 T8467 T8456 prep after,Quantification
R4859 T8468 T8469 nummod 22,hours
R4860 T8469 T8467 pobj hours,after
R4861 T8470 T8469 prep of,hours
R4862 T8471 T8470 pobj culture,of
R4863 T8472 T8473 mark that,were
R4864 T8473 T8457 ccomp were,demonstrated
R4865 T8474 T8475 nmod Ptdsr,macrophages
R4866 T8475 T8473 nsubj macrophages,were
R4867 T8476 T8474 punct -,Ptdsr
R4868 T8477 T8474 punct /,Ptdsr
R4869 T8478 T8474 punct -,Ptdsr
R4870 T8479 T8473 acomp able,were
R4871 T8480 T8481 aux to,secrete
R4872 T8481 T8479 xcomp secrete,able
R4873 T8482 T8483 det these,cytokines
R4874 T8483 T8481 dobj cytokines,secrete
R4875 T8484 T8483 amod anti-inflammatory,cytokines
R4876 T8485 T8481 prep upon,secrete
R4877 T8486 T8485 pobj ingestion,upon
R4878 T8487 T8486 prep of,ingestion
R4879 T8488 T8489 amod apoptotic,cells
R4880 T8489 T8487 pobj cells,of
R4881 T8490 T8481 punct ", ",secrete
R4882 T8491 T8492 mark although,at
R4883 T8492 T8481 advcl at,secrete
R4884 T8493 T8494 det a,level
R4885 T8494 T8492 pobj level,at
R4886 T8495 T8496 advmod slightly,lower
R4887 T8496 T8494 amod lower,level
R4888 T8497 T8494 prep than,level
R4889 T8498 T8499 amod wild,type
R4890 T8499 T8497 pobj type,than
R4891 T8500 T8499 punct -,type
R4892 T8501 T8502 punct (,b
R4893 T8502 T8457 parataxis b,demonstrated
R4894 T8503 T8502 nmod Figure,b
R4895 T8504 T8502 nmod 8a,b
R4896 T8505 T8502 punct ",",b
R4897 T8506 T8502 punct ),b
R4898 T8507 T8457 punct .,demonstrated
R4899 T8509 T8510 nsubj This,indicates
R4900 T8511 T8512 mark that,compromise
R4901 T8512 T8510 ccomp compromise,indicates
R4902 T8513 T8512 nsubj ablation,compromise
R4903 T8514 T8513 prep of,ablation
R4904 T8515 T8516 compound Ptdsr,function
R4905 T8516 T8514 pobj function,of
R4906 T8517 T8512 aux does,compromise
R4907 T8518 T8512 neg not,compromise
R4908 T8519 T8512 prep in,compromise
R4909 T8520 T8519 amod general,in
R4910 T8521 T8522 det the,ability
R4911 T8522 T8512 dobj ability,compromise
R4912 T8523 T8522 prep of,ability
R4913 T8524 T8523 pobj macrophages,of
R4914 T8525 T8526 aux to,release
R4915 T8526 T8522 acl release,ability
R4916 T8527 T8528 npadvmod immune,suppressive
R4917 T8528 T8530 amod suppressive,cytokines
R4918 T8529 T8528 punct -,suppressive
R4919 T8530 T8526 dobj cytokines,release
R4920 T8531 T8526 prep after,release
R4921 T8532 T8531 pobj recognition,after
R4922 T8533 T8532 cc and,recognition
R4923 T8534 T8532 conj engulfment,recognition
R4924 T8535 T8532 prep of,recognition
R4925 T8536 T8537 amod apoptotic,cells
R4926 T8537 T8535 pobj cells,of
R4927 T8538 T8510 punct .,indicates

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T8196 44-75 GO:0043277 denotes phagocytosis of apoptotic cells
T8197 60-75 CL:0000445 denotes apoptotic cells
T8198 70-75 CL_GO_EXT:cell denotes cells
T8199 103-108 PR_EXT:000009218 denotes Ptdsr
T8200 142-152 GO:0065007 denotes regulating
T8201 175-187 GO_PATO_EXT:inflammatory_process_or_quality denotes inflammatory
T8202 224-233 GO_PATO_EXT:apoptotic_process_or_quality denotes apoptotic
T8203 224-239 CL:0000445 denotes apoptotic cells
T8204 234-239 CL_GO_EXT:cell denotes cells
T8205 243-254 CL:0000235 denotes macrophages
T8206 289-294 PR_EXT:000009218 denotes Ptdsr
T8207 295-296 SO_EXT:sequence_nullness_or_absence denotes -
T8208 297-298 SO_EXT:sequence_nullness_or_absence denotes -
T8209 299-310 CL:0000235 denotes macrophages
T8210 324-331 GO_EXT:biological_release denotes release
T8211 337-349 GO_PATO_EXT:inflammatory_process_or_quality denotes inflammatory
T8212 350-359 GO_EXT:0005125 denotes cytokines
T8213 366-394 GO:0043652 denotes ingestion of apoptotic cells
T8214 379-394 CL:0000445 denotes apoptotic cells
T8215 389-394 CL_GO_EXT:cell denotes cells
T8216 418-424 PR_EXT:000000182 denotes TGF-β1
T8217 429-443 PR_EXT:000001471 denotes interleukin-10
T8218 445-450 PR_EXT:000001471 denotes IL-10
T8219 484-502 CHEBI:16412 denotes lipopolysaccharide
T8220 504-507 CHEBI:16412 denotes LPS
T8221 541-550 GO_PATO_EXT:apoptotic_process_or_quality denotes apoptotic
T8222 541-556 CL:0000445 denotes apoptotic cells
T8223 551-556 CL_GO_EXT:cell denotes cells
T8224 576-582 PR_EXT:000000182 denotes TGF-β1
T8225 587-592 PR_EXT:000001471 denotes IL-10
T8226 644-649 PR_EXT:000009218 denotes Ptdsr
T8227 650-651 SO_EXT:sequence_nullness_or_absence denotes -
T8228 652-653 SO_EXT:sequence_nullness_or_absence denotes -
T8229 654-665 CL:0000235 denotes macrophages
T8230 679-686 GO:0046903 denotes secrete
T8231 698-710 GO_PATO_EXT:inflammatory_process_or_quality denotes inflammatory
T8232 711-720 GO_EXT:0005125 denotes cytokines
T8233 726-754 GO:0043652 denotes ingestion of apoptotic cells
T8234 739-754 CL:0000445 denotes apoptotic cells
T8235 749-754 CL_GO_EXT:cell denotes cells
T8236 796-805 SO_EXT:wild_type_entity_or_quality denotes wild-type
T8237 853-858 PR_EXT:000009218 denotes Ptdsr
T8238 914-925 CL:0000235 denotes macrophages
T8239 929-936 GO_EXT:biological_release denotes release
T8240 937-943 UBERON:0002405 denotes immune
T8241 956-965 GO_EXT:0005125 denotes cytokines
T8242 988-1017 GO:0043652 denotes engulfment of apoptotic cells
T8243 1002-1017 CL:0000445 denotes apoptotic cells
T8244 1012-1017 CL_GO_EXT:cell denotes cells

craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T8106 44-75 GO:0043277 denotes phagocytosis of apoptotic cells
T8107 60-75 CL:0000445 denotes apoptotic cells
T8108 103-108 PR:000009218 denotes Ptdsr
T8109 142-152 GO:0065007 denotes regulating
T8110 224-239 CL:0000445 denotes apoptotic cells
T8111 243-254 CL:0000235 denotes macrophages
T8112 289-294 PR:000009218 denotes Ptdsr
T8113 299-310 CL:0000235 denotes macrophages
T8114 366-394 GO:0043652 denotes ingestion of apoptotic cells
T8115 379-394 CL:0000445 denotes apoptotic cells
T8116 418-424 PR:000000182 denotes TGF-β1
T8117 429-443 PR:000001471 denotes interleukin-10
T8118 445-450 PR:000001471 denotes IL-10
T8119 484-502 CHEBI:16412 denotes lipopolysaccharide
T8120 504-507 CHEBI:16412 denotes LPS
T8121 541-556 CL:0000445 denotes apoptotic cells
T8122 576-582 PR:000000182 denotes TGF-β1
T8123 587-592 PR:000001471 denotes IL-10
T8124 644-649 PR:000009218 denotes Ptdsr
T8125 654-665 CL:0000235 denotes macrophages
T8126 679-686 GO:0046903 denotes secrete
T8127 726-754 GO:0043652 denotes ingestion of apoptotic cells
T8128 739-754 CL:0000445 denotes apoptotic cells
T8129 853-858 PR:000009218 denotes Ptdsr
T8130 914-925 CL:0000235 denotes macrophages
T8131 937-943 UBERON:0002405 denotes immune
T8132 988-1017 GO:0043652 denotes engulfment of apoptotic cells
T8133 1002-1017 CL:0000445 denotes apoptotic cells

2_test

Id Subject Object Predicate Lexical cue
15345036-10811223-55938511 256-258 10811223 denotes 26