PMC:539297 / 445-1018 JSONTXT

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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/539297","sourcedb":"PMC","sourceid":"539297","source_url":"http://www.ncbi.nlm.nih.gov/pmc/539297","text":" generated Cln3Δex7/8 knock-in mice, which replicate the common JNCL mutation, express mutant battenin and display JNCL-like pathology.\n\nResults\nTo elucidate the consequences of the common JNCL mutation in neuronal cells, we used P4 knock-in mouse cerebella to establish conditionally immortalized CbCln3 wild-type, heterozygous, and homozygous neuronal precursor cell lines, which can be differentiated into MAP-2 and NeuN-positive, neuron-like cells. 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