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PMC:539297 / 24395-25311 JSONTXT

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craft-ca-core-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T4230 13-15 UBERON:0002037 denotes Cb
T4231 15-19 PR:000005591 denotes Cln3
T4232 20-28 CL:0000540 denotes neuronal
T4233 45-53 PR:000005591 denotes battenin
T4234 82-87 _FRAGMENT denotes early
T4235 97-106 GO:0005769 denotes endosomes
T4236 92-106 GO:0005770 denotes late endosomes
T4237 108-116 PR:000005591 denotes Battenin
T4238 146-148 UBERON:0002037 denotes Cb
T4239 148-152 PR:000005591 denotes Cln3
T4240 159-167 CL:0000540 denotes neuronal
T4241 259-268 GO:0005768 denotes endosomal
T4242 295-303 PR:000005591 denotes battenin
T4243 399-403 PR:000005591 denotes CLN3
T4244 404-412 PR:000005591 denotes battenin
T4245 478-492 GO:0005770 denotes late endosomes
T4246 497-506 GO:0005764 denotes lysosomes
T4247 514-522 CL:0000540 denotes neuronal
T4248 541-550 GO:0005764 denotes lysosomes
T4249 573-582 GO:0005768 denotes endosomes
T4250 593-600 CL:0000540 denotes neurons
T4251 635-643 PR:000005591 denotes battenin
T4252 667-676 GO:0031982 denotes vesicular
T4253 707-715 GO:0016020 denotes membrane
T4254 707-727 GO:0055085 denotes membrane trafficking
T4255 761-770 GO:0031982 denotes vesicular
T4256 761-780 GO:0016192 denotes vesicular transport
T4257 761-770 _FRAGMENT denotes vesicular
T4258 788-794 GO:0006906 denotes fusion
T4259 796-805 GO:0006897 denotes Endocytic
T4260 810-819 GO:0005764 denotes lysosomal
T4261 849-862 GO:0005739 denotes mitochondrial
T4262 849-872 GO:0000422 denotes mitochondrial autophagy
R2372 T4235 T4234 _lexicallyChainedTo endosomes,early
R2373 T4258 T4257 _lexicallyChainedTo fusion,vesicular

craft-sa-dev

Id Subject Object Predicate Lexical cue
T4843 0-2 IN denotes In
T4844 64-76 VBZ denotes co-localizes
T4845 3-7 JJ denotes wild
T4846 8-12 NN denotes type
T4847 7-8 HYPH denotes -
T4848 39-44 NNS denotes cells
T4849 13-19 NN denotes CbCln3
T4850 20-28 JJ denotes neuronal
T4904 443-451 VBN denotes reported
T4905 384-389 JJ denotes other
T4851 29-38 NN denotes precursor
T4852 45-53 NN denotes battenin
T4853 54-63 RB denotes primarily
T4854 77-81 IN denotes with
T4855 82-87 JJ denotes early
T4856 97-106 NNS denotes endosomes
T4857 88-91 CC denotes and
T4858 92-96 JJ denotes late
T4859 106-107 . denotes .
T4860 107-380 sentence denotes Battenin immunostaining in homozygous CbCln3Δex7/8 neuronal precursors is significantly reduced in abundance, but mutant signal also co-localizes with endosomal markers suggesting mutant battenin protein with C-terminal epitopes is trafficked similar to wild-type protein.
T4861 108-116 NN denotes Battenin
T4862 117-131 NN denotes immunostaining
T4863 196-203 VBN denotes reduced
T4864 132-134 IN denotes in
T4865 135-145 JJ denotes homozygous
T4866 168-178 NNS denotes precursors
T4867 146-156 NN denotes CbCln3Δex7
T4868 156-157 HYPH denotes /
T4869 157-158 CD denotes 8
T4870 159-167 JJ denotes neuronal
T4871 179-181 VBZ denotes is
T4872 182-195 RB denotes significantly
T4873 204-206 IN denotes in
T4874 207-216 NN denotes abundance
T4875 216-218 , denotes ,
T4876 218-221 CC denotes but
T4877 222-228 NN denotes mutant
T4878 229-235 NN denotes signal
T4879 241-253 VBZ denotes co-localizes
T4880 236-240 RB denotes also
T4881 254-258 IN denotes with
T4882 259-268 JJ denotes endosomal
T4883 269-276 NNS denotes markers
T4884 277-287 VBG denotes suggesting
T4885 288-294 NN denotes mutant
T4886 304-311 NN denotes protein
T4887 295-303 NN denotes battenin
T4888 340-350 VBN denotes trafficked
T4889 312-316 IN denotes with
T4890 317-318 NN denotes C
T4891 319-327 JJ denotes terminal
T4892 318-319 HYPH denotes -
T4893 328-336 NNS denotes epitopes
T4894 337-339 VBZ denotes is
T4895 351-358 JJ denotes similar
T4896 359-361 IN denotes to
T4897 362-366 JJ denotes wild
T4898 367-371 NN denotes type
T4899 366-367 HYPH denotes -
T4900 372-379 NN denotes protein
T4901 379-380 . denotes .
T4902 380-601 sentence denotes In other studies, CLN3/battenin protein localization has been reported to partially overlap with late endosomes and lysosomes in non-neuronal cells [7], and to lysosomes, synaptosomes [8] and endosomes [9,25] in neurons.
T4903 381-383 IN denotes In
T4906 390-397 NNS denotes studies
T4907 397-399 , denotes ,
T4908 399-403 NN denotes CLN3
T4909 421-433 NN denotes localization
T4910 403-404 HYPH denotes /
T4911 404-412 NN denotes battenin
T4912 413-420 NN denotes protein
T4913 434-437 VBZ denotes has
T4914 438-442 VBN denotes been
T4915 452-454 TO denotes to
T4916 465-472 VB denotes overlap
T4917 455-464 RB denotes partially
T4918 473-477 IN denotes with
T4919 478-482 JJ denotes late
T4920 483-492 NNS denotes endosomes
T4921 493-496 CC denotes and
T4922 497-506 NNS denotes lysosomes
T4923 507-509 IN denotes in
T4924 510-522 JJ denotes non-neuronal
T4925 523-528 NNS denotes cells
T4926 529-530 -LRB- denotes [
T4927 530-531 CD denotes 7
T4928 531-532 -RRB- denotes ]
T4929 532-534 , denotes ,
T4930 534-537 CC denotes and
T4931 538-540 IN denotes to
T4932 541-550 NNS denotes lysosomes
T4933 550-552 , denotes ,
T4934 552-564 NNS denotes synaptosomes
T4935 565-566 -LRB- denotes [
T4936 566-567 CD denotes 8
T4937 567-568 -RRB- denotes ]
T4938 569-572 CC denotes and
T4939 573-582 NNS denotes endosomes
T4940 583-584 -LRB- denotes [
T4941 586-588 CD denotes 25
T4942 584-585 CD denotes 9
T4943 585-586 , denotes ,
T4944 588-589 -RRB- denotes ]
T4971 761-770 JJ denotes vesicular
T4972 771-780 NN denotes transport
T4973 781-784 CC denotes and
T4974 784-785 HYPH denotes /
T4975 785-787 CC denotes or
T4976 788-794 NN denotes fusion
T4977 794-795 . denotes .
T4978 795-916 sentence denotes Endocytic and lysosomal-targeted pathways, including mitochondrial autophagy, are specifically implicated in this study.
T4979 796-805 JJ denotes Endocytic
T4980 820-828 VBN denotes targeted
T4981 806-809 CC denotes and
T4982 810-819 JJ denotes lysosomal
T4983 819-820 HYPH denotes -
T4984 829-837 NNS denotes pathways
T4985 891-901 VBN denotes implicated
T4986 837-839 , denotes ,
T4987 839-848 VBG denotes including
T4988 849-862 JJ denotes mitochondrial
T4989 863-872 NN denotes autophagy
T4990 872-874 , denotes ,
T4991 874-877 VBP denotes are
T4992 878-890 RB denotes specifically
T4993 902-904 IN denotes in
T4994 905-909 DT denotes this
T4995 910-915 NN denotes study
T4996 915-916 . denotes .
T4957 655-656 DT denotes a
T4958 657-663 NN denotes subset
T4959 664-666 IN denotes of
T4960 667-676 JJ denotes vesicular
T4961 677-689 NNS denotes compartments
T4962 690-697 VBG denotes linking
T4963 698-706 JJ denotes multiple
T4964 728-736 NNS denotes pathways
T4965 707-715 NN denotes membrane
T4966 716-727 NN denotes trafficking
T4967 736-738 , denotes ,
T4968 738-745 RB denotes perhaps
T4969 746-757 VBG denotes functioning
T4945 590-592 IN denotes in
T4946 593-600 NNS denotes neurons
T4947 600-601 . denotes .
T4948 601-795 sentence denotes These data jointly indicate that battenin resides in a subset of vesicular compartments linking multiple membrane trafficking pathways, perhaps functioning in vesicular transport and/or fusion.
T4949 602-607 DT denotes These
T4950 608-612 NNS denotes data
T4951 621-629 VBP denotes indicate
T4952 613-620 RB denotes jointly
T4953 630-634 IN denotes that
T4954 644-651 VBZ denotes resides
T4955 635-643 NN denotes battenin
T4956 652-654 IN denotes in
T4970 758-760 IN denotes in
R2780 T4843 T4844 prep In,co-localizes
R2781 T4845 T4846 amod wild,type
R2782 T4846 T4848 nmod type,cells
R2783 T4847 T4846 punct -,type
R2784 T4848 T4843 pobj cells,In
R2785 T4849 T4848 nmod CbCln3,cells
R2786 T4850 T4851 amod neuronal,precursor
R2787 T4851 T4848 compound precursor,cells
R2788 T4852 T4844 nsubj battenin,co-localizes
R2789 T4853 T4844 advmod primarily,co-localizes
R2790 T4854 T4844 prep with,co-localizes
R2791 T4855 T4856 amod early,endosomes
R2792 T4856 T4854 pobj endosomes,with
R2793 T4857 T4855 cc and,early
R2794 T4858 T4855 conj late,early
R2795 T4859 T4844 punct .,co-localizes
R2796 T4861 T4862 compound Battenin,immunostaining
R2797 T4862 T4863 nsubjpass immunostaining,reduced
R2798 T4864 T4862 prep in,immunostaining
R2799 T4865 T4866 amod homozygous,precursors
R2800 T4866 T4864 pobj precursors,in
R2801 T4867 T4866 nmod CbCln3Δex7,precursors
R2802 T4868 T4867 punct /,CbCln3Δex7
R2803 T4869 T4867 nummod 8,CbCln3Δex7
R2804 T4870 T4866 amod neuronal,precursors
R2805 T4871 T4863 auxpass is,reduced
R2806 T4872 T4863 advmod significantly,reduced
R2807 T4873 T4863 prep in,reduced
R2808 T4874 T4873 pobj abundance,in
R2809 T4875 T4863 punct ", ",reduced
R2810 T4876 T4863 cc but,reduced
R2811 T4877 T4878 compound mutant,signal
R2812 T4878 T4879 nsubj signal,co-localizes
R2813 T4879 T4863 conj co-localizes,reduced
R2814 T4880 T4879 advmod also,co-localizes
R2815 T4881 T4879 prep with,co-localizes
R2816 T4882 T4883 amod endosomal,markers
R2817 T4883 T4881 pobj markers,with
R2818 T4884 T4879 advcl suggesting,co-localizes
R2819 T4885 T4886 compound mutant,protein
R2820 T4886 T4888 nsubjpass protein,trafficked
R2821 T4887 T4886 compound battenin,protein
R2822 T4888 T4884 advcl trafficked,suggesting
R2823 T4889 T4886 prep with,protein
R2824 T4890 T4891 npadvmod C,terminal
R2825 T4891 T4893 amod terminal,epitopes
R2826 T4892 T4891 punct -,terminal
R2827 T4893 T4889 pobj epitopes,with
R2828 T4894 T4888 auxpass is,trafficked
R2829 T4895 T4888 advcl similar,trafficked
R2830 T4896 T4895 prep to,similar
R2831 T4897 T4898 amod wild,type
R2832 T4898 T4900 compound type,protein
R2833 T4899 T4898 punct -,type
R2834 T4900 T4896 pobj protein,to
R2835 T4901 T4879 punct .,co-localizes
R2836 T4903 T4904 prep In,reported
R2837 T4905 T4906 amod other,studies
R2838 T4906 T4903 pobj studies,In
R2839 T4907 T4904 punct ", ",reported
R2840 T4908 T4909 nmod CLN3,localization
R2841 T4909 T4904 nsubjpass localization,reported
R2842 T4910 T4908 punct /,CLN3
R2843 T4911 T4912 compound battenin,protein
R2844 T4912 T4908 appos protein,CLN3
R2845 T4913 T4904 aux has,reported
R2846 T4914 T4904 auxpass been,reported
R2847 T4915 T4916 aux to,overlap
R2848 T4916 T4904 xcomp overlap,reported
R2849 T4917 T4916 advmod partially,overlap
R2850 T4918 T4916 prep with,overlap
R2858 T4926 T4927 punct [,7
R2859 T4927 T4916 parataxis 7,overlap
R2860 T4928 T4927 punct ],7
R2861 T4929 T4916 punct ", ",overlap
R2862 T4930 T4916 cc and,overlap
R2863 T4931 T4916 conj to,overlap
R2864 T4932 T4931 pobj lysosomes,to
R2865 T4933 T4932 punct ", ",lysosomes
R2866 T4934 T4932 conj synaptosomes,lysosomes
R2867 T4935 T4936 punct [,8
R2868 T4936 T4934 parataxis 8,synaptosomes
R2869 T4937 T4936 punct ],8
R2870 T4938 T4934 cc and,synaptosomes
R2871 T4939 T4934 conj endosomes,synaptosomes
R2872 T4940 T4941 punct [,25
R2873 T4941 T4939 parataxis 25,endosomes
R2874 T4942 T4941 nummod 9,25
R2875 T4943 T4941 punct ",",25
R2876 T4944 T4941 punct ],25
R2877 T4945 T4931 prep in,to
R2878 T4946 T4945 pobj neurons,in
R2879 T4947 T4904 punct .,reported
R2880 T4949 T4950 det These,data
R2881 T4950 T4951 nsubj data,indicate
R2882 T4952 T4951 advmod jointly,indicate
R2883 T4953 T4954 mark that,resides
R2884 T4954 T4951 ccomp resides,indicate
R2885 T4955 T4954 nsubj battenin,resides
R2886 T4956 T4954 prep in,resides
R2887 T4957 T4958 det a,subset
R2888 T4958 T4956 pobj subset,in
R2889 T4959 T4958 prep of,subset
R2890 T4960 T4961 amod vesicular,compartments
R2891 T4961 T4959 pobj compartments,of
R2892 T4962 T4961 acl linking,compartments
R2893 T4963 T4964 amod multiple,pathways
R2894 T4964 T4962 dobj pathways,linking
R2895 T4965 T4966 compound membrane,trafficking
R2896 T4966 T4964 compound trafficking,pathways
R2897 T4967 T4954 punct ", ",resides
R2898 T4968 T4969 advmod perhaps,functioning
R2899 T4969 T4954 advcl functioning,resides
R2900 T4970 T4969 prep in,functioning
R2901 T4971 T4972 amod vesicular,transport
R2902 T4972 T4970 pobj transport,in
R2903 T4973 T4972 cc and,transport
R2904 T4974 T4973 punct /,and
R2905 T4975 T4973 cc or,and
R2906 T4976 T4972 conj fusion,transport
R2907 T4977 T4951 punct .,indicate
R2908 T4979 T4980 amod Endocytic,targeted
R2909 T4980 T4984 amod targeted,pathways
R2910 T4981 T4979 cc and,Endocytic
R2911 T4982 T4979 conj lysosomal,Endocytic
R2912 T4983 T4980 punct -,targeted
R2913 T4984 T4985 nsubjpass pathways,implicated
R2914 T4986 T4984 punct ", ",pathways
R2915 T4987 T4984 prep including,pathways
R2916 T4988 T4989 amod mitochondrial,autophagy
R2917 T4989 T4987 pobj autophagy,including
R2918 T4990 T4985 punct ", ",implicated
R2919 T4991 T4985 auxpass are,implicated
R2920 T4992 T4985 advmod specifically,implicated
R2921 T4993 T4985 prep in,implicated
R2922 T4994 T4995 det this,study
R2923 T4995 T4993 pobj study,in
R2924 T4996 T4985 punct .,implicated
R2851 T4919 T4920 amod late,endosomes
R2852 T4920 T4918 pobj endosomes,with
R2853 T4921 T4920 cc and,endosomes
R2854 T4922 T4920 conj lysosomes,endosomes
R2855 T4923 T4916 prep in,overlap
R2856 T4924 T4925 amod non-neuronal,cells
R2857 T4925 T4923 pobj cells,in

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the chain model. You can change it to the bag model.

Id Subject Object Predicate Lexical cue
T4365 3-12 SO_EXT:wild_type_entity_or_quality denotes wild-type
T4366 13-15 UBERON:0002037 denotes Cb
T4367 15-19 PR_EXT:000005591 denotes Cln3
T4368 20-28 CL:0000540 denotes neuronal
T4369 39-44 CL_GO_EXT:cell denotes cells
T4370 45-53 PR_EXT:000005591 denotes battenin
T4371 67-76 GO_PATO_EXT:biological_localization_process_or_quality denotes localizes
T4372 82-87 _FRAGMENT denotes early
T4373 97-106 GO:0005769 denotes endosomes
T4374 92-106 GO:0005770 denotes late endosomes
T4375 108-116 PR_EXT:000005591 denotes Battenin
T4376 146-148 UBERON:0002037 denotes Cb
T4377 148-152 PR_EXT:000005591 denotes Cln3
T4378 159-167 CL:0000540 denotes neuronal
T4379 222-228 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T4380 244-253 GO_PATO_EXT:biological_localization_process_or_quality denotes localizes
T4381 259-268 GO:0005768 denotes endosomal
T4382 269-276 CHEBI_SO_EXT:molecular_indicator_or_label_or_marker_or_tag denotes markers
T4383 288-294 SO_EXT:sequence_altered_entity_or_alteration_process denotes mutant
T4384 295-303 PR_EXT:000005591 denotes battenin
T4385 304-311 CHEBI_PR_EXT:protein denotes protein
T4386 317-327 CHEBI_SO_EXT:C_terminus_or_C_terminal_region denotes C-terminal
T4387 328-336 CHEBI_SO_EXT:epitope denotes epitopes
T4388 340-350 GO_EXT:biological_routing_or_transport denotes trafficked
T4389 362-371 SO_EXT:wild_type_entity_or_quality denotes wild-type
T4390 372-379 CHEBI_PR_EXT:protein denotes protein
T4391 399-403 PR_EXT:000005591 denotes CLN3
T4392 404-412 PR_EXT:000005591 denotes battenin
T4393 413-420 CHEBI_PR_EXT:protein denotes protein
T4394 421-433 GO_PATO_EXT:biological_localization_process_or_quality denotes localization
T4395 478-492 GO:0005770 denotes late endosomes
T4396 497-506 GO:0005764 denotes lysosomes
T4397 514-522 CL:0000540 denotes neuronal
T4398 523-528 CL_GO_EXT:cell denotes cells
T4399 541-550 GO:0005764 denotes lysosomes
T4400 573-582 GO:0005768 denotes endosomes
T4401 593-600 CL:0000540 denotes neurons
T4402 635-643 PR_EXT:000005591 denotes battenin
T4403 667-676 GO:0031982 denotes vesicular
T4404 707-715 GO:0016020 denotes membrane
T4405 707-727 GO:0055085 denotes membrane trafficking
T4406 761-770 GO:0031982 denotes vesicular
T4407 761-780 GO:0016192 denotes vesicular transport
T4408 761-770 _FRAGMENT denotes vesicular
T4409 788-794 GO:0006906 denotes fusion
T4410 796-805 GO:0006897 denotes Endocytic
T4411 810-819 GO:0005764 denotes lysosomal
T4412 820-828 GO_EXT:biological_routing_or_transport denotes targeted
T4413 849-862 GO:0005739 denotes mitochondrial
T4414 849-872 GO:0000422 denotes mitochondrial autophagy
R2380 T4373 T4372 _lexicallyChainedTo endosomes,early
R2381 T4409 T4408 _lexicallyChainedTo fusion,vesicular

2_test

Id Subject Object Predicate Lexical cue
15588329-14622109-12950157 530-531 14622109 denotes 7
15588329-11590129-12950158 566-567 11590129 denotes 8
15588329-14699076-12950159 584-585 14699076 denotes 9
15588329-15240864-12950160 586-588 15240864 denotes 25