PMC:509410 / 16897-17181
Annnotations
craft-sa-dev
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We show that targeted expression of an activated form of PPARδ produces profound and coordinated increases in oxidation enzymes, mitochondrial biogenesis, and production of specialized type I fiber contractile proteins—the three hallmarks for muscle fiber type switching (Figure 6C)."}
craft-ca-core-ex-dev
{"project":"craft-ca-core-ex-dev","denotations":[{"id":"T3055","span":{"begin":23,"end":33},"obj":"GO:0010467"},{"id":"T3056","span":{"begin":58,"end":63},"obj":"PR_EXT:000013057"},{"id":"T3057","span":{"begin":111,"end":120},"obj":"MOP:0000568"},{"id":"T3058","span":{"begin":121,"end":128},"obj":"CHEBI_GO_SO_EXT:enzyme"},{"id":"T3059","span":{"begin":130,"end":143},"obj":"GO:0005739"},{"id":"T3060","span":{"begin":144,"end":154},"obj":"GO_EXT:biogenesis_or_biosynthesis"},{"id":"T3061","span":{"begin":160,"end":173},"obj":"_FRAGMENT"},{"id":"T3062","span":{"begin":211,"end":219},"obj":"GO:0006412"},{"id":"T3063","span":{"begin":186,"end":198},"obj":"CL:0002211"},{"id":"T3064","span":{"begin":199,"end":210},"obj":"GO:0006936"},{"id":"T3065","span":{"begin":211,"end":219},"obj":"CHEBI_PR_EXT:protein"},{"id":"T3066","span":{"begin":244,"end":250},"obj":"UBERON_EXT:muscle_structure_or_tissue"},{"id":"T3067","span":{"begin":244,"end":256},"obj":"CL:0000187"}],"relations":[{"id":"R2167","pred":"_lexicallyChainedTo","subj":"T3062","obj":"T3061"}],"text":" We show that targeted expression of an activated form of PPARδ produces profound and coordinated increases in oxidation enzymes, mitochondrial biogenesis, and production of specialized type I fiber contractile proteins—the three hallmarks for muscle fiber type switching (Figure 6C)."}
craft-ca-core-dev
{"project":"craft-ca-core-dev","denotations":[{"id":"T2972","span":{"begin":23,"end":33},"obj":"GO:0010467"},{"id":"T2973","span":{"begin":58,"end":63},"obj":"PR:000013057"},{"id":"T2974","span":{"begin":111,"end":120},"obj":"MOP:0000568"},{"id":"T2975","span":{"begin":130,"end":143},"obj":"GO:0005739"},{"id":"T2976","span":{"begin":160,"end":173},"obj":"_FRAGMENT"},{"id":"T2977","span":{"begin":211,"end":219},"obj":"GO:0006412"},{"id":"T2978","span":{"begin":186,"end":198},"obj":"CL:0002211"},{"id":"T2979","span":{"begin":199,"end":210},"obj":"GO:0006936"},{"id":"T2980","span":{"begin":244,"end":256},"obj":"CL:0000187"}],"relations":[{"id":"R2165","pred":"_lexicallyChainedTo","subj":"T2977","obj":"T2976"}],"text":" We show that targeted expression of an activated form of PPARδ produces profound and coordinated increases in oxidation enzymes, mitochondrial biogenesis, and production of specialized type I fiber contractile proteins—the three hallmarks for muscle fiber type switching (Figure 6C)."}