PMC:5056896 / 7807-8422 JSONTXT

{"project":"2_test","denotations":[{"id":"27729841-26175662-44843559","span":{"begin":237,"end":239},"obj":"26175662"}],"text":"Molecular docking between miRNA-mRNA and AGO protein\nDocking between three dimensional structure of protein and ligand, may be a biomolecule like miRNA or a gene is an efficient computational method to inspect the molecular interaction [61]. Docking were performed between AGO protein and miRNA-mRNA duplexes (miR-106 and PTEN; miR-21 and TGFBR2; and miR-29b-2 and VEGFA) using PatchDock web server (http://bioinfo3d.cs.tau.ac.il/PatchDock/),algorithm ranked the docked complexes on the basis of highest geometrical shape complementary scores. The molecular interaction was studied using Discovery Studio 3.5 suite."}