PMC:4635215 / 816-1678
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4635215","sourcedb":"PMC","sourceid":"4635215","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4635215","text":"The Golgi complex plays a central role in processing and sorting of biosynthetic cargo in all eukaryotic cells. In mammals, the Golgi complex consists of sets of flattened cisternal membranes arranged in stacks with associated tubules and vesicles, which are usually collected at the microtubule organizing center (MTOC) in a ribbon structure (Klumperman, 2011). This structure is not essential for the known functions of the Golgi, and may suggest additional functions. Golgi structure is also quite dynamic; the organelle is disassembled at mitosis and then reassembled (Wang and Seemann, 2011). The organelle can also accommodate cargo of different shapes and sizes (Machamer, 2013). We previously hypothesized that mammalian Golgi organization may have evolved in part to sense and transduce specific stress signals to the nucleus (Hicks and Machamer, 2005).","tracks":[{"project":"TEST0","denotations":[{"id":"26594142-232-240-125939","span":{"begin":356,"end":360},"obj":"[\"21502307\"]"},{"id":"26594142-120-128-125940","span":{"begin":591,"end":595},"obj":"[\"21690214\"]"},{"id":"26594142-82-90-125941","span":{"begin":680,"end":684},"obj":"[\"23821163\"]"},{"id":"26594142-169-177-125942","span":{"begin":856,"end":860},"obj":"[\"15979510\"]"}],"attributes":[{"subj":"26594142-232-240-125939","pred":"source","obj":"TEST0"},{"subj":"26594142-120-128-125940","pred":"source","obj":"TEST0"},{"subj":"26594142-82-90-125941","pred":"source","obj":"TEST0"},{"subj":"26594142-169-177-125942","pred":"source","obj":"TEST0"}]},{"project":"0_colil","denotations":[{"id":"26594142-21502307-125939","span":{"begin":356,"end":360},"obj":"21502307"},{"id":"26594142-21690214-125940","span":{"begin":591,"end":595},"obj":"21690214"},{"id":"26594142-23821163-125941","span":{"begin":680,"end":684},"obj":"23821163"},{"id":"26594142-15979510-125942","span":{"begin":856,"end":860},"obj":"15979510"}],"attributes":[{"subj":"26594142-21502307-125939","pred":"source","obj":"0_colil"},{"subj":"26594142-21690214-125940","pred":"source","obj":"0_colil"},{"subj":"26594142-23821163-125941","pred":"source","obj":"0_colil"},{"subj":"26594142-15979510-125942","pred":"source","obj":"0_colil"}]},{"project":"2_test","denotations":[{"id":"26594142-21502307-38084411","span":{"begin":356,"end":360},"obj":"21502307"},{"id":"26594142-21690214-38084412","span":{"begin":591,"end":595},"obj":"21690214"},{"id":"26594142-23821163-38084413","span":{"begin":680,"end":684},"obj":"23821163"},{"id":"26594142-15979510-38084414","span":{"begin":856,"end":860},"obj":"15979510"}],"attributes":[{"subj":"26594142-21502307-38084411","pred":"source","obj":"2_test"},{"subj":"26594142-21690214-38084412","pred":"source","obj":"2_test"},{"subj":"26594142-23821163-38084413","pred":"source","obj":"2_test"},{"subj":"26594142-15979510-38084414","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"TEST0","color":"#93ec9a","default":true},{"id":"0_colil","color":"#ec93a5"},{"id":"2_test","color":"#93bfec"}]}]}}