PMC:4572492 / 55735-57033 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4572492","sourcedb":"PMC","sourceid":"4572492","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4572492","text":"Table 2 Apical Gene-Set and SLC9A3 Complex Association Analysis with CF Lung Disease Severity as Measured by SaKnorm in the Canadian Gene Modifier Study Discovery Sample and in the French Replication Sample\nLocation-only Test Scale-only Test JLS-Fisher Test\nApical Gene-Set (3,814 SNPs)\nCanadian Discovery Sample 0.0876 0.0222 0.0099\nFrench replication sample 0.2058 0.0077 0.0180\nSLC9A3 Gene-Based (10 SNPs)\nCanadian Discovery Sample \u003c0.0001 0.0238 0.0001\nFrench replication sample 0.0953 0.0415 0.0286\nApical Gene-Set Excluding SLC9A3 (3,804 SNPs)\nCanadian Discovery Sample 0.1319 0.0248 0.0161\nFrench replication sample 0.2139 0.0076 0.0182\nSLC9A3 Complex: SLC9A3, SLC9A3R1, SLC9A3R2, and EZR (38 SNPs)\nCanadian Discovery Sample \u003c0.0001 0.0016 \u003c0.0001\nFrench replication sample 0.2390 0.0245 0.0415\nApical Gene-Set Excluding the SLC9A3 Complex (3,776 SNPs)\nCanadian Discovery Sample 0.178 0.0329 0.0329\nFrench replication sample 0.2173 0.0099 0.0201\nIndividual location-only and scale-only tests and the joint location-scale Fisher (JLS-Fisher) test were performed in the full CGS (n = 1,409) and French (n = 1,232) samples using unrelated individuals (see Material and Methods and Results). p values reported were estimated from 10,000 permutation replicates.","divisions":[{"label":"label","span":{"begin":0,"end":7}},{"label":"caption","span":{"begin":9,"end":207}},{"label":"p","span":{"begin":9,"end":207}},{"label":"table","span":{"begin":208,"end":987}},{"label":"tr","span":{"begin":208,"end":262}},{"label":"th","span":{"begin":208,"end":227}},{"label":"th","span":{"begin":228,"end":244}},{"label":"th","span":{"begin":246,"end":262}},{"label":"tr","span":{"begin":263,"end":292}},{"label":"td","span":{"begin":263,"end":292}},{"label":"tr","span":{"begin":292,"end":341}},{"label":"td","span":{"begin":292,"end":317}},{"label":"td","span":{"begin":319,"end":325}},{"label":"td","span":{"begin":327,"end":333}},{"label":"td","span":{"begin":335,"end":341}},{"label":"tr","span":{"begin":342,"end":391}},{"label":"td","span":{"begin":342,"end":367}},{"label":"td","span":{"begin":369,"end":375}},{"label":"td","span":{"begin":377,"end":383}},{"label":"td","span":{"begin":385,"end":391}},{"label":"tr","span":{"begin":392,"end":420}},{"label":"td","span":{"begin":392,"end":420}},{"label":"tr","span":{"begin":420,"end":470}},{"label":"td","span":{"begin":420,"end":445}},{"label":"td","span":{"begin":447,"end":454}},{"label":"td","span":{"begin":456,"end":462}},{"label":"td","span":{"begin":464,"end":470}},{"label":"tr","span":{"begin":471,"end":520}},{"label":"td","span":{"begin":471,"end":496}},{"label":"td","span":{"begin":498,"end":504}},{"label":"td","span":{"begin":506,"end":512}},{"label":"td","span":{"begin":514,"end":520}},{"label":"tr","span":{"begin":521,"end":567}},{"label":"td","span":{"begin":521,"end":567}},{"label":"tr","span":{"begin":567,"end":616}},{"label":"td","span":{"begin":567,"end":592}},{"label":"td","span":{"begin":594,"end":600}},{"label":"td","span":{"begin":602,"end":608}},{"label":"td","span":{"begin":610,"end":616}},{"label":"tr","span":{"begin":617,"end":666}},{"label":"td","span":{"begin":617,"end":642}},{"label":"td","span":{"begin":644,"end":650}},{"label":"td","span":{"begin":652,"end":658}},{"label":"td","span":{"begin":660,"end":666}},{"label":"tr","span":{"begin":667,"end":729}},{"label":"td","span":{"begin":667,"end":729}},{"label":"tr","span":{"begin":729,"end":780}},{"label":"td","span":{"begin":729,"end":754}},{"label":"td","span":{"begin":756,"end":763}},{"label":"td","span":{"begin":765,"end":771}},{"label":"td","span":{"begin":773,"end":780}},{"label":"tr","span":{"begin":781,"end":830}},{"label":"td","span":{"begin":781,"end":806}},{"label":"td","span":{"begin":808,"end":814}},{"label":"td","span":{"begin":816,"end":822}},{"label":"td","span":{"begin":824,"end":830}},{"label":"tr","span":{"begin":831,"end":889}},{"label":"td","span":{"begin":831,"end":889}},{"label":"tr","span":{"begin":889,"end":937}},{"label":"td","span":{"begin":889,"end":914}},{"label":"td","span":{"begin":916,"end":921}},{"label":"td","span":{"begin":923,"end":929}},{"label":"td","span":{"begin":931,"end":937}},{"label":"tr","span":{"begin":938,"end":987}},{"label":"td","span":{"begin":938,"end":963}},{"label":"td","span":{"begin":965,"end":971}},{"label":"td","span":{"begin":973,"end":979}},{"label":"td","span":{"begin":981,"end":987}}],"tracks":[]}